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A case of renal primary neuroendocrine tumor (G3) in which 177Lu-PRRT was effective for disease control 177Lu-PRRT有效控制肾原发性神经内分泌肿瘤（G3） 1例
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-01 DOI: 10.1016/j.eucr.2025.103337
Saki Inaba , Toshiki Kijima , Mina Takaoka , Toshitaka Uematsu , Kohei Takei , Masahiro Yashi , Kazuyuki Ishida , Taku Aoki , Takao Kamai
{"title":"A case of renal primary neuroendocrine tumor (G3) in which 177Lu-PRRT was effective for disease control","authors":"Saki Inaba ,&nbsp;Toshiki Kijima ,&nbsp;Mina Takaoka ,&nbsp;Toshitaka Uematsu ,&nbsp;Kohei Takei ,&nbsp;Masahiro Yashi ,&nbsp;Kazuyuki Ishida ,&nbsp;Taku Aoki ,&nbsp;Takao Kamai","doi":"10.1016/j.eucr.2025.103337","DOIUrl":"10.1016/j.eucr.2025.103337","url":null,"abstract":"<div><div>Primary renal neuroendocrine tumor (NET) is extremely rare, with no established treatment for advanced cases. We report high-grade (G3) renal NET effectively treated with peptide receptor radionuclide therapy (PRRT). A 30-year-old man was diagnosed with primary renal NET G3 with liver metastases. After everolimus failure, he received 177Lu-DOTATATE (Lutathera®). Although the tumor continued growing after the first cycle, disease stabilized from the second cycle onwards. Stable disease was maintained for 12 months without severe adverse events, preserving quality of life. 177Lu-PRRT is a promising therapeutic option for high-grade, somatostatin receptor-positive renal NET when other treatments fail.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103337"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145898022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of complex renal stones in horseshoe kidney using real-time intrarenal pressure monitoring with artificial intelligence in retrograde intrarenal surgery: A case report 应用人工智能实时监测逆行肾内手术治疗马蹄肾复杂肾结石1例
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-02-03 DOI: 10.1016/j.eucr.2026.103366
Armand Achmadsyah , Favian Ariiq Rahmat , Nadhif Faza Ananda , Mukhlis Akmal Taher , Gerhard Reinaldi Situmorang , Widi Atmoko , Nur Rasyid , Ponco Birowo
{"title":"Management of complex renal stones in horseshoe kidney using real-time intrarenal pressure monitoring with artificial intelligence in retrograde intrarenal surgery: A case report","authors":"Armand Achmadsyah ,&nbsp;Favian Ariiq Rahmat ,&nbsp;Nadhif Faza Ananda ,&nbsp;Mukhlis Akmal Taher ,&nbsp;Gerhard Reinaldi Situmorang ,&nbsp;Widi Atmoko ,&nbsp;Nur Rasyid ,&nbsp;Ponco Birowo","doi":"10.1016/j.eucr.2026.103366","DOIUrl":"10.1016/j.eucr.2026.103366","url":null,"abstract":"<div><div>Retrograde intrarenal surgery (RIRS) in horseshoe kidneys is technically challenging due to altered anatomy and unstable intrarenal pressure (IRP). We report a case of a 45-year-old male with complex renal stones in a horseshoe kidney managed using artificial intelligence (AI)-assisted real-time IRP monitoring during RIRS. The AI system dynamically regulated irrigation and suction to maintain IRP within a safe range (∼30 mmHg), improving intraoperative visibility and procedural control. Stone clearance was achieved without complications. This case highlights the feasibility and potential safety benefits of AI-assisted IRP monitoring in anatomically complex kidneys.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103366"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146188679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Papillary urothelial tumor of low malignant potential in a pediatric patient: case associated with Poland syndrome 小儿患者低恶性潜能乳头状尿路上皮肿瘤：与波兰综合征相关的病例
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1016/j.eucr.2026.103348
Katherine Arias , Myriam Lili Ceballos , Juan Lukas Ordoñez , Edwin Abraham Medina , Manuel Duque
{"title":"Papillary urothelial tumor of low malignant potential in a pediatric patient: case associated with Poland syndrome","authors":"Katherine Arias ,&nbsp;Myriam Lili Ceballos ,&nbsp;Juan Lukas Ordoñez ,&nbsp;Edwin Abraham Medina ,&nbsp;Manuel Duque","doi":"10.1016/j.eucr.2026.103348","DOIUrl":"10.1016/j.eucr.2026.103348","url":null,"abstract":"<div><div>Papillary urothelial tumor of low malignant potential is rare in pediatric patients, accounting for only 0.1–0.4 % of bladder tumors under 20 years of age. We present the case of a 14-year-old female with Poland syndrome and history of laryngeal, nasal, and colonic polyposis presented with intermittent gross hematuria, suprapubic pain, and urinary incontinence. Transurethral resection (TUR) identified a papillary urothelial neoplasm of low malignant potential. Genetic testing revealed an ARMC4 variant (primary ciliary dyskinesia), with no known association to PUNLMP. This case highlights the importance of a stepwise approach including early imaging, histologic confirmation, and endoscopic monitoring.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103348"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Combination of PKD and precocious puberty in a HNF1B mutated little girl 一个HNF1B突变小女孩罕见的PKD和性早熟组合
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.eucr.2026.103353
Ersilia Nigro , Rosamunda D'Arcangelo , Antonio Pisani , Gabriele Malgieri , Aurora Daniele
{"title":"Rare Combination of PKD and precocious puberty in a HNF1B mutated little girl","authors":"Ersilia Nigro ,&nbsp;Rosamunda D'Arcangelo ,&nbsp;Antonio Pisani ,&nbsp;Gabriele Malgieri ,&nbsp;Aurora Daniele","doi":"10.1016/j.eucr.2026.103353","DOIUrl":"10.1016/j.eucr.2026.103353","url":null,"abstract":"<div><div>Among the genes involved in ADKPD, HNF1B encodes a transcription factor implicated in kidneys morphogenesis. Here, we present the case of a little girl with multiple renal cysts diagnosed in utero; at 4 years the genetic testing by NGS revealed the rare pathogenic variant c.1462C &gt; T in the HNF1 gene; additionally, overweight and precocious puberty with appearance of pubic hair were suspected. At 7 years, she was obese with right breast bud, adipomastia and accelerated growth. Our experience highlights the diagnostic difficulties associated with an atypical PKD phenotype and underlines the importance of a holistic approach including diagnosis and early therapies.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103353"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From kidney to eye: The devastating consequences of delayed diagnosis 从肾脏到眼睛：延迟诊断的毁灭性后果。
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-02-09 DOI: 10.1016/j.eucr.2026.103370
Derrick Tsang, Antony Raharja, Antoine Safi, Konstantinos Kapriniotis, Simon Holden, Cordelia McKechnie
{"title":"From kidney to eye: The devastating consequences of delayed diagnosis","authors":"Derrick Tsang,&nbsp;Antony Raharja,&nbsp;Antoine Safi,&nbsp;Konstantinos Kapriniotis,&nbsp;Simon Holden,&nbsp;Cordelia McKechnie","doi":"10.1016/j.eucr.2026.103370","DOIUrl":"10.1016/j.eucr.2026.103370","url":null,"abstract":"<div><div>Sepsis workup, including urine cultures, should be routine in renal masses when imaging suggests malignancy. This is to avert vision-threatening consequences in older, immunocompromised patients as seen in this rare case where C. koserii renal abscess was misdiagnosed as a renal cell carcinoma and was complicated by endogenous endophthalmitis (EE), confirmed by urine culture and vitreous PCR. Despite intravitreal antibiotics and pars plana vitrectomy, vision loss was permanent. The renal abscess responded to systemic antibiotics eventually. C. koserii EE is rare and carries poor visual prognosis as shown in previous few cases reported.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103370"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A urologic manifestation of carney complex: Bilateral Sertoli tumors and scrotal myxoma in an adolescent male 卡尼综合征的泌尿学表现：一例青春期男性双侧支持瘤和阴囊黏液瘤。
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-02-16 DOI: 10.1016/j.eucr.2026.103383
Evan Walter , Avery Wolfe , Zhongxin Yu , Adam Rensing
{"title":"A urologic manifestation of carney complex: Bilateral Sertoli tumors and scrotal myxoma in an adolescent male","authors":"Evan Walter ,&nbsp;Avery Wolfe ,&nbsp;Zhongxin Yu ,&nbsp;Adam Rensing","doi":"10.1016/j.eucr.2026.103383","DOIUrl":"10.1016/j.eucr.2026.103383","url":null,"abstract":"<div><div>Carney complex (CNC) is a rare tumor syndrome caused by mutations in the PRKAR1A gene, characterized by endocrine tumors, cardiac and cutaneous myxomas, pigmented lesions, and testicular tumors. One to two thirds of affected males develop large cell calcifying Sertoli cell tumors (LCCSCTs), with rare involvement of scrotal soft tissues. We present a case of CNC in an adolescent male with bilateral LCCSCTs and a very large scrotal myxoma, resulting in azoospermia and pain requiring surgical management. This report highlights the urologic manifestations of CNC and outlines appropriate evaluation, treatment, and surveillance strategies relevant to pediatric and adolescent urologic practice.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103383"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147327626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zinner syndrome: Late-Diagnosis in a 55-year-old male and favorable outcome after surgical excision - A case report and review of the literature 津纳综合征：一名55岁男性的晚期诊断和手术切除后的良好结果-一个病例报告和文献回顾
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2025-12-30 DOI: 10.1016/j.eucr.2025.103332
Kinh Luan Thai , Duy Dien Nguyen , Do La Quach , Nho Tinh Le , Le Quy Van Dinh , Minh Dinh Nguyen , Ryan Dobbs , Ho Trong Tan Truong , Tuan Thanh Nguyen , Xuan Thai Ngo
{"title":"Zinner syndrome: Late-Diagnosis in a 55-year-old male and favorable outcome after surgical excision - A case report and review of the literature","authors":"Kinh Luan Thai ,&nbsp;Duy Dien Nguyen ,&nbsp;Do La Quach ,&nbsp;Nho Tinh Le ,&nbsp;Le Quy Van Dinh ,&nbsp;Minh Dinh Nguyen ,&nbsp;Ryan Dobbs ,&nbsp;Ho Trong Tan Truong ,&nbsp;Tuan Thanh Nguyen ,&nbsp;Xuan Thai Ngo","doi":"10.1016/j.eucr.2025.103332","DOIUrl":"10.1016/j.eucr.2025.103332","url":null,"abstract":"<div><div>Zinner Syndrome (ZS) is a rare congenital anomaly defined by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. We report a 55-year-old male presenting with chronic perineal pain and LUTS. Imaging confirmed ZS (right renal agenesis, 3.3 × 3.8 cm seminal vesicle cyst). The patient underwent surgical excision, converting from laparoscopic to open due to dense adhesions. He achieved complete symptom resolution and remained stable at two-year follow-up. ZS should be considered in older males with non-specific LUTS. Surgery is effective, and advanced imaging is crucial for diagnosis.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103332"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145898041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Durable complete radiographic and biochemical response to olaparib in BRCA2-mutated metastatic castration-resistant prostate cancer: a long-term responder case 在brca2突变的转移性阉割抵抗性前列腺癌中，奥拉帕尼持久的完全放射学和生化反应：一个长期反应病例。
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-27 DOI: 10.1016/j.eucr.2026.103356
Fumihiro Ito, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Takashi Fujita
{"title":"Durable complete radiographic and biochemical response to olaparib in BRCA2-mutated metastatic castration-resistant prostate cancer: a long-term responder case","authors":"Fumihiro Ito,&nbsp;Koki Kobayashi,&nbsp;Gaku Hayashi,&nbsp;Shunsuke Kamijo,&nbsp;Takashi Fujita","doi":"10.1016/j.eucr.2026.103356","DOIUrl":"10.1016/j.eucr.2026.103356","url":null,"abstract":"<div><div>Poly(ADP-ribose) polymerase inhibitors are an important option for metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair gene alterations, although durable complete responses remain rare. We report a 72-year-old man with BRCA2-mutated mCRPC who achieved a sustained complete response to olaparib monotherapy. After progression on androgen deprivation therapy, abiraterone, enzalutamide, and docetaxel, genomic profiling identified a pathogenic BRCA2 alteration. Olaparib induced an undetectable prostate-specific antigen within three months, maintained for over 27 months, with complete resolution of bone metastases. This case highlights the potential for durable responses to olaparib and the importance of early genomic testing.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103356"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive non-functioning Adrenocortical carcinoma presenting as acute abdomen without rupture: A case report 大块无功能的肾上腺皮质癌表现为急性腹部而无破裂：1例报告
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1016/j.eucr.2026.103350
Shady H.Y.B. Girgis , Ihab H.Y. Barsoum , Shady Elia Anis , Mostafa Elgamal , Hany Yassa
{"title":"Massive non-functioning Adrenocortical carcinoma presenting as acute abdomen without rupture: A case report","authors":"Shady H.Y.B. Girgis ,&nbsp;Ihab H.Y. Barsoum ,&nbsp;Shady Elia Anis ,&nbsp;Mostafa Elgamal ,&nbsp;Hany Yassa","doi":"10.1016/j.eucr.2026.103350","DOIUrl":"10.1016/j.eucr.2026.103350","url":null,"abstract":"<div><div>Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with diverse clinical presentations. Acute abdomen is an exceptionally uncommon manifestation, typically reflecting tumor rupture. We report a 39-year-old male presenting with acute abdominal pain and a palpable left upper-quadrant mass. Imaging demonstrated a massive adrenal tumor (17.8 × 15.1 × 20.2cm). En-bloc resection with negative margins was achieved without rupture while preserving adjacent organs. Histopathology confirmed ACC. The patient remains disease-free 36 months postoperatively without adjuvant therapy. Acute abdomen can be the presenting symptom of ACC even without tumor rupture. Timely intervention can prevent possible impending rupture, enabling complete resection and favorable oncological outcomes.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103350"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prostatic development and verumontanum in a 46,XX karyotype : An embryological paradox redefining diagnostic algorithm for testicular DSD 46，xx核型的前列腺发育和睾丸：一个重新定义睾丸DSD诊断算法的胚胎学悖论
IF 0.4
Urology Case Reports Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.eucr.2026.103339
Rifqi Yanda Muhammad , Joko Pitoyo
{"title":"Prostatic development and verumontanum in a 46,XX karyotype : An embryological paradox redefining diagnostic algorithm for testicular DSD","authors":"Rifqi Yanda Muhammad ,&nbsp;Joko Pitoyo","doi":"10.1016/j.eucr.2026.103339","DOIUrl":"10.1016/j.eucr.2026.103339","url":null,"abstract":"<div><div>Evaluation of 46,XX Disorders of Sex Development (DSD) with severe virilization often yields inconclusive results. We report a case where alternative diagnostics resolved a significant phenotype-karyotype discordance. A 2-year-old with a 46,XX karyotype and penoscrotal hypospadias was evaluated. Diagnostic urethroscopy revealed definitive prostatic tissue and a verumontanum. These findings provided anatomical evidence of Wolffian differentiation, distinct from Müllerian persistence, and incompatible with Congenital Adrenal Hyperplasia (CAH). Identifying the prostate established the diagnosis of 46,XX Testicular DSD, shifting management from gonadectomy to hypospadias repair. Urethroscopy is indispensable for resolving diagnostic discrepancies missed by standard protocols.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103339"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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