Muhammad Fajar , Ikhlas Arief Bramono , Fakhri Rahman , Farilaila Rayhani , Edward Usfie Harahap , Rachmat Budi Santoso
{"title":"前列腺癌伴阴茎同步转移性病变1例","authors":"Muhammad Fajar , Ikhlas Arief Bramono , Fakhri Rahman , Farilaila Rayhani , Edward Usfie Harahap , Rachmat Budi Santoso","doi":"10.1016/j.eucr.2025.103172","DOIUrl":null,"url":null,"abstract":"<div><div>Prostate cancer with penile metastasis is exceedingly rare. We report a synchronous metastatic hormone-sensitive prostate cancer presenting initially as a penile lesion in a 70-year-old male. Penile tumor excision confirmed prostate adenocarcinoma by immunohistochemistry. MRI revealed prostate enlargement without lymph node involvement; biopsy indicated Gleason Score 3 + 3 adenocarcinoma, and bone scan showed pubic bone metastasis. Initial PSA was significantly elevated (318 ng/ml). Androgen deprivation therapy led to progressive PSA decline and good clinical response. Aggressive surgical intervention for penile metastasis is discouraged due to limited benefits and potential deterioration in quality of life.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"62 ","pages":"Article 103172"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prostate cancer with synchronous metastatic penile lesion: A case report\",\"authors\":\"Muhammad Fajar , Ikhlas Arief Bramono , Fakhri Rahman , Farilaila Rayhani , Edward Usfie Harahap , Rachmat Budi Santoso\",\"doi\":\"10.1016/j.eucr.2025.103172\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Prostate cancer with penile metastasis is exceedingly rare. We report a synchronous metastatic hormone-sensitive prostate cancer presenting initially as a penile lesion in a 70-year-old male. Penile tumor excision confirmed prostate adenocarcinoma by immunohistochemistry. MRI revealed prostate enlargement without lymph node involvement; biopsy indicated Gleason Score 3 + 3 adenocarcinoma, and bone scan showed pubic bone metastasis. Initial PSA was significantly elevated (318 ng/ml). Androgen deprivation therapy led to progressive PSA decline and good clinical response. Aggressive surgical intervention for penile metastasis is discouraged due to limited benefits and potential deterioration in quality of life.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"62 \",\"pages\":\"Article 103172\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025002438\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025002438","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Prostate cancer with synchronous metastatic penile lesion: A case report
Prostate cancer with penile metastasis is exceedingly rare. We report a synchronous metastatic hormone-sensitive prostate cancer presenting initially as a penile lesion in a 70-year-old male. Penile tumor excision confirmed prostate adenocarcinoma by immunohistochemistry. MRI revealed prostate enlargement without lymph node involvement; biopsy indicated Gleason Score 3 + 3 adenocarcinoma, and bone scan showed pubic bone metastasis. Initial PSA was significantly elevated (318 ng/ml). Androgen deprivation therapy led to progressive PSA decline and good clinical response. Aggressive surgical intervention for penile metastasis is discouraged due to limited benefits and potential deterioration in quality of life.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
