Infectio最新文献

{"title":"Recipe ingredients for re emergent protozoa: climatic change, rain, zoonosis, mountain and food","authors":"J. Gómez‐Marín, Yimmi Pinto, F. Lora, H. Mantilla-Meluk","doi":"10.22354/24223794.1080","DOIUrl":"https://doi.org/10.22354/24223794.1080","url":null,"abstract":"1 Grupo de Investigación en Población Infantil (IPI), Hospital Universitario San Juan de Dios, Armenia, Quindío, Colombia 2 Grupo de Estudio en Parasitología Molecular (GEPAMOL), Centro de Investigaciones Biomédicas, Universidad del Quindío, Armenia, Quindío, Colombia 3 https://orcid.org/0000-0002-8842-091X 4 Grupo de Investigación en Ciencias Básicas y Educación, Universidad del Quindío, Armenia, Quindío, Colombia. https://orcid.org/0000-0003-00943044 0000-0003-0094-3044 5 Editor en Jefe, Revista Infectio. https://orcid.org/0000-0001-6472-3329 6 Centro de Estudios de Alta Montaña (CEAM), Colombia. Universidad del Quindío. http://orcid.org/0000-0001-8134-3694 Recibido: 18/07/2022; Aceptado: 19/07/2022","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42165726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidencia de fungemia en la unidad de recién nacidos del Hospital Universitario San Ignacio de Bogotá en el periodo comprendido desde el 01 de enero de 2008 hasta el 31 de diciembre de 2018","authors":"Maria Sánchez-Tordecilla, A. Bertolotto-Cepeda, Yaris Vargas-Vaca, L. P. Montaña-Jiménez, A. Bohórquez-Peñaranda","doi":"10.22354/24223794.1089","DOIUrl":"https://doi.org/10.22354/24223794.1089","url":null,"abstract":"Objetivo: determinar la incidencia de fungemia en neonatos del Hospital Universitario San Ignacio de Bogotá, y caracterizar a los que desarrollaron infección fúngica invasora, en el periodo entre 2008 y 2018. Material y método: estudio de casos y controles anidado a una cohorte retrospectiva, con información obtenida de las bases de datos de los departamentos de microbiología y estadística, así como las historias clínicas. Resultados: En el periodo de estudio se atendieron en total 12.905 neonatos; población en la cual se encontró una tasa de incidencia de 6,2 por 10.000 pacientes con una distribución equitativa por sexos y una mediana de edad gestacional de 36,5 semanas, siendo el principal agente causal la Candida albicans (50%). En los casos se reportó uso de antibiótico de amplio espectro en el 75%, de nutrición parenteral en el 100%, cirugía previa en el 75% (principalmente de tipo gastrointestinal 83,3%), uso de catéter venoso central en el 100% e inicio de alimentación trófica temprana en el 12,5%. Finalmente, no se documentó uso de corticoides postnatales en la muestra. Conclusiones: se encontró una baja incidencia de fungemia en el HUSI, lo que refuerza la no necesidad de implementar el uso de profilaxis antimicótica de forma estandarizada en nuestra institución. Entre los casos identificados, la patología quirúrgica gastrointestinal surgió como la condición clínica prevalente debido a los requerimientos de uso de nutrición parenteral por catéter venoso central.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43124082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological characteristics of whooping cough in Paraguay (2005-2019)","authors":"M. E. León, A. Kawabata, M. Nagai, Liliana Rojas, Nancy Melgarejo, Gustavo Chamorro","doi":"10.22354/24223794.1081","DOIUrl":"https://doi.org/10.22354/24223794.1081","url":null,"abstract":"Objective: To describe the epidemiological characteristics of whooping cough in Paraguay. Methods: 5327 samples of children and adults of all ages with suspected whooping cough and their contacts were included in this study. 745 samples were processed per microbiological culture and 4582 samples per microbiological culture and PCR. Results: The overall frequency of cases and their laboratory-confirmed contacts was 9.1%. A total of 361 cases and 123 close case contacts were detected as positive. Positive cases were more common in the < 2 months (70.6%), followed by the 2-6 month (11.9%). Conclusion: In Paraguay it is a public health problem that mainly affects children under 2 months, who have not yet received the vaccine. Knowing the epidemiology of whooping cough or pertussis helps us to know the burden of the disease as well as to measure the effectiveness and impact of vaccines.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45083994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ergotamina y terapia antiretroviral: una combinación peligrosa. Reporte de caso","authors":"Juan M. Hernandez-Torres, Ayleen Rivera-Tenorio, Stephanya Moreno-Ortega, Álvaro Arbeláez-Cortés, Yany Magali Chamorro, Janier D. Segura-Cheng","doi":"10.22354/24223794.1098","DOIUrl":"https://doi.org/10.22354/24223794.1098","url":null,"abstract":"El ergotismo es una condición clínica rara caracterizada por vasoconstricción generalizada producida por la administración de medicamentos derivados del Ergot. Principalmente mediado por la interacción entre medicamentos, entre ellos figuran los antibióticos, anticonceptivos orales y antivirales. Se presenta el caso de un paciente de 28 años, con infección por virus de la inmunodeficiencia humana en manejo antirretroviral con inhibidores de la proteasa que consumió concomitantemente ergotamina con lo cual desarrollo dolor intenso, frialdad, parestesias y cianosis de los miembros inferiores asociado a una lesión ulcerada en el dorso del pie derecho, se consideró episodio de vasoespasmo secundario a ergotismo, dentro del diferencial toman relevancia las vasculitis. Presentó mejoría tras la suspensión de los medicamentos que estaban relacionados y el uso de vasodilatador. El propósito del caso es hacer énfasis en una interacción medicamentosa grave como lo es la de la ergotamina más inhibidores de la proteasa.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46728749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 screening in asymptomatic patients scheduled for surgery. What is the role of rt-PCR in elective procedures during the pandemic?","authors":"J. Cala-García, Isabel Virginia Hernández-Linares, Joan Sebastian Barrera-Guaca, Claudia Viviana Jaimes-Gonzalez, Andrés De Vivero, Luis Eduardo Cavelier-Castro, C. Pérez-Díaz","doi":"10.22354/24223794.1083","DOIUrl":"https://doi.org/10.22354/24223794.1083","url":null,"abstract":"Background: COVID-19 has changed medical practice nowadays. One of the biggest concerns has been establishing when invasive procedures such as surgery, GI endoscopy or bone marrow transplant are safe; and if it is necessary to consider screening for asymptomatic patients. Methods: We identified asymptomatic patients that were scheduled for invasive procedures from May 2020 to April 2021 at Clínica de Marly. Patients were asked to fill a questionnaire about GI and upper respiratory symptoms and contact with possible/confirmed cases of COVID- 19 in the last 15 days. Patients taken to emergency procedures, who had symptoms or contact with probable/confirmed cases in the last 15 days were excluded. rt-PCR was performed to screen COVID-19. Results: A total of 1837 patients were included. 104 rt-PCRs tested positive for SARS-CoV-2, leading to a 5.66% of identified asymptomatic patients. Patients were followed-up on the 30th day after the procedure. 1733 negative patients responded to our follow-up, in which only 1 death and 2 complications were detected. 102 positive patients were followed-up and no complications or deaths were reported. Conclusions: We found the presence of 5.66% of asymptomatic patients with positive rt-PCR for COVID-19. Safe screening will decide if these invasive interventions can be postponed, or, if the benefit outweighs the risks.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43334754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lysinebacillum Bacteriemia in an Adult Cancer patient","authors":"Samuel Martínez-Vernaza, J. Garzón-Herazo, Katherine García-Guzman, S. I. Cuervo-Maldonado","doi":"10.22354/24223794.1095","DOIUrl":"https://doi.org/10.22354/24223794.1095","url":null,"abstract":"Lysinibacillus is a genus of rod-shaped gram-positive bacteria most often found in soil and plantlife, however, it has been isolated from air and from the human intestinal microbiome as well. The genus Lysinibacillus is most often disregarded when isolated in the laboratory; nevertheless, it usually acts as an opportunist in immunocompromise hosts with various mortality rates. Here we present a case of bacteriemia due to Lysinibacillus in a patient whose clinical history and risk factors suggested otherwise. It is crucial to pay attention to the identification of this types of organisms, particularly, when they come from techniques such as spectroscopy. This in order to have a broader picture when addressing this type of patients.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48195017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trauma, poisoning and envenomation caused by fish in Brazil: a review","authors":"M. M. Novelli, R. Feio, S. Montenegro, Ademir N Ribeiro-Júnior, R. Siqueira-Batista","doi":"10.22354/24223794.1093","DOIUrl":"https://doi.org/10.22354/24223794.1093","url":null,"abstract":"Injuries caused by traumatic, poisonous and venomous animal are relatively common in the medical practice of many regions, especially in tropical countries, such as Brazil. These include morbid events caused by a wide variety of fish. Although they are generally of low severity, restricted to local manifestations of the place where the venom/poison comes into contact with the skin or mucosa, these illnesses can evolve to more severe conditions which, in rarer cases, can lead to death. The potential severity in some cases, along with the recent increase in the number of notifications, in different areas of the country, demonstrate the need for a better understanding of these events. Based on these considerations, the present article aims to review the literature on the main characteristics of trauma, poisoning and envenomation by fish in Brazil, with emphasis on the causative animals and on the pathophysiological, clinical and therapeutic aspects of these morbid conditions","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48161741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caracterización transcriptómica de bacterias relacionadas con eubiosis y disbiosis en pacientes con y sin carcinoma escamocelular oral","authors":"Alveiro Erira, Fredy Gamboa, Ángel Cid-Arregui, Fabián Tobar-Tosse, D. García","doi":"10.22354/24223794.1092","DOIUrl":"https://doi.org/10.22354/24223794.1092","url":null,"abstract":"Objetivo. Caracterizar la expresión génica de 40 especies bacterianas compatibles con procesos de eubiosis y disbiosis en pacientes con y sin OSCC Material y Método. Se realizó un estudio descriptivo de corte transversal en muestras de placa y saliva de 10 pacientes con OSCC y 10 sin OSCC con géneros y edades similares, mínimo 4 dientes en boca. ARN total fue extraído y secuenciado mediante HiSeq™ 2500 de Illumina. Se analizaron secuencias con herramientas bioinformáticas (trimmomatic, SortMeRNA, BMTagger, RNA-Seq, bowtie2 y kraken2) y bases de datos (PATRIC, CARD, VICTORS). Resultados. El grupo de eubiosis S. macedonicus, S. lutetiensis, S. infantarius, S. parauberis, L. helveticus, T. intermedia, S. novella y E. asburiae expresaron 169 genes, y el grupo de disbiosis L. pneumophila, M. hominis, M. conjunctivae, G. vaginalis, C. canimorsus, P. stuartii expresaron 76 genes, la actividad transcripcional se relacionó con metabolismo de carbohidratos, nucleótidos, aminoácidos y energía, que a su vez se asoció con resistencia a antibióticos, factores de virulencia, blancos de medicamentos y transporte. Conclusión. La actividad transcripcional de S. macedonicus, S. infantarius, S. lutetiensis, S.pasteurianus, S. parauberis, C. violaceum y S. novella se asocia con procesos de eubiosis y T. intermedia y P. stuartii con procesos de disbiosis.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46479639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Active surveillance of adult healthcareassociated infections in intensive care units: resistance and molecular profile in an upper middle-income country","authors":"M. Ochoa-Díaz, Eduardo Santero-Santurino, Amando Flores-Diaz, Eva Camacho-Fernández, María Paulina Osorio-Cortina, Doris Gómez-Camargo","doi":"10.22354/24223794.1077","DOIUrl":"https://doi.org/10.22354/24223794.1077","url":null,"abstract":"Objective: This study aimed to characterize epidemiological and molecular profile of Healthcare-associated infections [HAI] in 21 intensive care units (ICU) in a city in Colombia. Methods: Descriptive study of prevalence. Adult patients were screened in 21 ICUs for HAIs: VAP, CLABSI; CAUTI and/or SSI. Microbiological and genotypic identification was performed. Results: Prevalence of HAIs was 41.4% (CI 36.9-45.9).VAP 15.8% (CI 12.7-19.4); CLABSI, 13.5% (CI 10.6-16.9); CAUTI, 7.7% (CI 5.5-10.5); and SSI, 4.4% (CI 2.7-6.6). Gram-negative bacteria (71.7%) predominated (P. aeruginosa (19.1%), K. pneumoniae (13.4%) and E. coli (13%)). Pseudomonas spp. 20-30% were resistant to carbapenems and greater than 10% to aztreonam, 3rd- and 4th-generation cephalosporins, and Beta-lactamase inhibitors. In VAP and CLABSI, 30% of Staphylococcus aureus were resistant to oxacillin. In CAUTI, Staphylococcus epidermidis exhibited 100% resistance. In P. aeruginosa resistance gene were blaTEM, blaSHV, and blaCTX-M (15- 32%), KPC (5.7%), and oxacillinases blaOXA-48 (1.8%) and blaOXA-1-40-30 (20-50%). In E. coli, genes qnrB, qnrS and qnrD were identified. In CLABSI, ermC-type (16.7%), aph[2’]’If (7.7%) and ant[4’]-Ia (7.7%) were identified in Staphylococcus aureus. Conclusions: VAP and CLABSI predominate in ICUs evaluated in Colombia due to resistant gram-negative bacteria by ESBL-type resistance genes plasmids, efflux pumps hindering the therapeutic approach.","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48840094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Section 2. Colombian consensus for prophylaxis, treatment and prevention of invasive aspergillosis in adult and pediatric patients","authors":"J. Oñate, Pilar Rivas-Pinedo, C. Saavedra-Trujillo, G. Camacho-Moreno, S. I. Cuervo-Maldonado, L. Enciso‐Olivera, B. Patiño-Escobar, J. P. Osorio-Lombana, I. Berrio, C. Álvarez-Moreno, J. C. Gómez-Rincón, S. Restrepo-Gualteros, Ximena Castañeda-Luquerna, F. Guevara, Jorge I. Marín-Uribe, J. Patiño-Niño, J. F. García-Goez, Adriana M Celis, Franco E Montúfar, Eduardo López-Medina, Dinno Fernández-Chico, Hugo Fernández-Suarez, Christian Pallares G","doi":"10.22354/24223794.1064","DOIUrl":"https://doi.org/10.22354/24223794.1064","url":null,"abstract":"The invasive aspergillosis (IA) continues to be an important cause of morbidity and mortality, difficult to manage in severely immunocompromised patients, however, with its appearance in a heterogeneous group of patients (e.g., critical ICU patients, patients with human immunodeficiency virus [HIV/AIDS], etc.), who were not classically considered high risk, as well as more chronic forms of aspergillosis, (including those with a propensity for invasion), which have been better defined, different antifungal treatment modalities have been established for Aspergillus-associated infections according to the specific patient’s condition. The understanding of the different risk factors for the development of IFI/IA, which are constantly evolving, and which include, among others, the underlying malignancy, the associated condition and treatment, the presence of comorbidities, environmental exposure, and the presence of certain genetic polymorphisms in the patient, allows for a more precise risk stratification, which together with the use of diagnostic algorithms, would allow the characterization of patients who would benefit from the different early intervention strategies, and the optimization of management protocols. The evaluation of the clinical manifestations of the patient is an essential step, as it involves the site of infection, the severity and dynamic nature of immunosuppression, and the characteristics of the etiological agent involved, which with the use of imaging modalities (with an increasingly important role in diagnosis), and of novel and accessible diagnostic tools, useful for the detection and follow-up of the disease, allow the early recognition of the infection, the selection of an early antifungal treatment, the use of more effective antifungal drugs and the development of local clinical practice guidelines","PeriodicalId":38132,"journal":{"name":"Infectio","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45996746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}