Ekologiya Cheloveka (Human Ecology)最新文献

{"title":"CORRECTIVE EFFECT OF DIHYDROQUERCETIN ON THE STATE OF OXIDATIVE METABOLISM IN YOUNG ATHLETES IN WINTER SPORTS UNDER CONDITIONS NORTHERN REGION","authors":"Vladimir Ivanovich Korchin, Tatyana Yakovlevna Korchina, Elena Petrovna Fedorova, Sergey Viktorovich Nehoroshev, Aleksandra Viktorovna Nehorosheva","doi":"10.17816/humeco321267","DOIUrl":"https://doi.org/10.17816/humeco321267","url":null,"abstract":"AIM: To study the effect of dihydroquercetin on the indicators of oxidative metabolism in young athletes engaged in the winter sports in the Khanty-Mansiysk Autonomous Okrug (KhMAO).
 MATERIAL AND METHODS: The indicators of oxidative metabolism were studied in a group of 56 male students (mean age 19.300.51 years) from the Khanty-Mansiysk boarding school of the Olympic reserve. These students were actively involved in winter sports such as cross-country skiing and biathlon. To assess the impact of the plant-derived antioxidant bioflavonoid Baikal dihydroquercetin (DHQ), the participants were administered a daily dose of 120 mg of DHQ for a period of 60 days. Measurements were taken before and after the exposure. Blood lipid peroxidation (LPO) products were studied, namely, lipid hydroperoxides (LHP) and products that react with 2-thiobarbituric acid products (PR-TBA). Additionally, we examined the indicators of the body's antioxidant defense system (ADS) through the assessment of total antioxidant activity (TAA) and thiol status (TS). To quantify the overall oxidative stress experienced by the participants, we calculated the oxidative stress coefficient (OSC) using the formula: OSC = LHP PR-TBA / TAA TS.
 RESULTS: The average levels of LPO values (HPL and PR-TBA) among KhMAO athletes have surpassed the upper limit of optimal values. On the other hand, the ADS parameters (TAA and TS) fall within the range of physiologically optimal values, albeit closer to the lower limit. Notably, athletes have exhibited an OSC increase that is nearly 3.5 times higher than the maximum allowable value. A quarter of the individuals examined displayed elevated HPL values, while more than 30% showed increased PR-TBA levels. A third of male athletes exhibited reduced ADS values compared to the physiologically optimal range. In total, 70.4% of skiers and biathletes in KhMAO have exceeded the OSC parameters. After two months of daily intake of 120 mg DHQ, the normalization of indicators of oxidative metabolism was observed. All parameters aligned with physiologically optimal values, except for OSC. We found a decrease in primary (LHP, 1.15 times) and secondary (PR-TBA, p=0.046) LPO indicators parallel to a significant increase in ADS indicators, specifically TAA (p=0.022) and TS (p=0.049). Conversely, there was a significant increase in ADS indicators, specifically TAA (p=0.022) and TS (p=0.049).
 Despite these positive changes, the OSC value, although significantly reduced (p 0.001) by 2.3 times compared to the initial value, remained above the upper limit of the physiological norm.
 CONCLUSION: The study demonstrated that young athletes engaged in winter sports experienced improved indicators of oxidative metabolism after a consistent two-month intake of the potent antioxidant DHQ. This led to the restoration of a balanced prooxidant-antioxidant state, enhanced overall well-being, and expedited recovery following intense physical exertion. Furtherm","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135648367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of air pollution (literature review)","authors":"Michail Pozdnyakov, Svyatoslav Mazilov, Svetlana V Raikova, Yury S Gusev, Natalia E Komleva, Anatoly N Mikerov","doi":"10.17816/humeco456406","DOIUrl":"https://doi.org/10.17816/humeco456406","url":null,"abstract":"This article provides a comprehensive overview of global practices in assessing atmospheric air quality in different countries. The review is based on scientific literature, regulatory frameworks, and methodological documents. It delves into the specificities of pollutant regulation in various countries, including Russia, and compares the standards established in each. Substantial differences in the approaches to the regulation of pollutants in the atmospheric have been identified between the countries.
 Furthermore, this study examines the methods for assessing air quality and instrumental control. It explores renowned mathematical models used for evaluating and predicting atmospheric air quality. Notably, the findings reveal striking similarities between data obtained through predictive modeling and field measurements. However, the utilization of an extensive network of measurement stations enables the acquisition of the most precise and up-to-date information on atmospheric pollutant concentrations.
 Moreover, this article offers an overview of online services available globally for real-time monitoring of atmospheric air quality. These platforms play a crucial role in providing immediate insights into the state of the air we breathe. Additionally, the article presents the methods employed for assessing the health risks associated with atmospheric pollutant levels and their impact on the population health.
 It has been established that the countries of Europe, the USA, and China have achieved significant success in the field of atmospheric air quality control. Residents in these countries have access to up-to-date information about the state of atmospheric air in real-time. However, in Russia, despite ongoing assessments of air quality, there is currently no public service available that provides comprehensive information on atmospheric air quality.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135648368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REPRODUCTIVE HEALTH OF UNDERAGE LIVING IN THE IRKUTSK REGION UNDER MODERN CONDITIONS","authors":"L Rychkova, Tatjana Astakhova, О Bugun, Е Khramova","doi":"10.17816/humeco109241","DOIUrl":"https://doi.org/10.17816/humeco109241","url":null,"abstract":"BACKGROUND: The reproductive potential of adolescent girls includes several parameters, such as general and gynecological morbidity, physical and sexual development, psychosocial readiness for partnership and motherhood. Therefore, it is crucial to consider these parameters when assessing the reproductive capacity of adolescent girls in different settings.
 AIM: To study the reproductive health and reproductive behavior of girls residing in Tofalaria.
 MATERIAL AND METHODS: A total of 194 girls participated in the study, with 58 of them being Tofalars. These girls were aged between 11 and 17 years old and resided in the Nizhneudinsk district of the Irkutsk region. The study involved analyzing medical records, conducting examinations by an obstetrician-gynecologist, collecting clinical samples from the urogenital tract for microscopy to detect transmitted infections, and performing colposcopy.
 RESULTS: The average age of onset of menarche among the study participants was between 11.5 and 12.0 years. Tofalar girls were more likely to experience menstrual cycle disorders such as oligomenorrhea and abnormal uterine bleeding. Additionally, delayed puberty was more commonly observed among Tofalar girls. Reproductive behavior of the Tofalar girls was characterized by early engagement in relationships, promiscuity, high prevalence of sexually transmitted infections, and high proportion of unplanned pregnancies.
 CONCLUSION: There is a need to develop and implement a long-term strategy on preserving the reproductive health of adolescents and young people in the Irkutsk region through consolidating the efforts of civil society institutions and governmental agencies at both regional and municipal levels.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135648369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polymorphism of folate metabolism genes in students studying in the subarctic region of Russia","authors":"Nadezda Vorobyeva, Alyona Vorobyeva, Alexandra Sergeevna Voronsova, Elizaveta Y Melnichuk","doi":"10.17816/humeco456493","DOIUrl":"https://doi.org/10.17816/humeco456493","url":null,"abstract":"AIM: analysis of epidemiology of the spread of polymorphism of folate metabolism genes in various ethnic groups Russians and Indians living in the Arctic region of Russia. METHODS: epidemiological, prospective, cross-sectional population study was performed on a sample of ethnic Indians and Russians, natives of the Arkhangelsk region.RESULTS: A questionnaire survey of participants and a molecular genetic study of genes determining folate metabolism were conducted by real-time PCR. During the study, the participants were divided into two groups a group of Russian ethnos and a group of Indian ethnos. A comparative analysis of the frequencies of the spread of polymorphism of folate metabolism genes in the two studied groups was carried out.
 CONCLUSION: russian participants were more likely to carry the unfavorable allele T polymorphism rs1801133 of the MTHFR gene in comparison with the group of ethnic Indians, which indicates an increased risk of folate metabolism disorders in the group of Russian participants.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135981544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF CARCINOGENIC RISK FROM EXPOSURE TO CHEMICALS FROM FOOD PRODUCTS BASED ON REGIONAL EXPOSURE FACTORS","authors":"O. Frolova","doi":"10.17816/humeco217681","DOIUrl":"https://doi.org/10.17816/humeco217681","url":null,"abstract":"BACKGROUND. At present, a lot of data has been accumulated indicating the risks of developing various toxic effects caused by exposure to chemicals that enter the human body with contaminated food. \u0000AIM. Evaluation of the carcinogenic risk to the health of the population of the Republic of Tatarstan associated with chemical contamination of food products based on regional exposure factors. \u0000METHODS. To assess the risk, the results of studies of food raw materials and food products for the period 2006-2019, carried out by the testing laboratory center of the FBUZ \"Center for Hygiene and Epidemiology in the Republic of Tatarstan (Tatarstan)\" were used. Calculations were made for the following groups of food raw materials and foodstuffs: meat and meat products; fish and fish products; milk and dairy products; bread and bakery products; sugar and confectionery; vegetables and melons (excluding potatoes); potato; fruits and berries; vegetable oils; eggs. \u0000RESULTS. As a result of the hazard identification, it was found that the following substances contained in food are of priority for the subsequent assessment of carcinogenic risk: hexachlorane, alpha-lindane, beta-lindane, lindane, heptachlor, cypermethrin, dichlorodiphenyltrichloroethane (DDT) and its metabolites, benzo(a) pyrene, derivatives of 2,4-dichlorophenoxyacetic acid (2,4-D), arsenic, cadmium, lead. It has been established that the total carcinogenic risk from exposure to the studied chemicals that contaminate food products ranges from alarming (7.9 10-4) to high (2.2 10-3 - 1.9 10-2) for various exposure schemes . \u0000CONCLUSION. The total carcinogenic risk is formed mainly as a result of contamination with pesticides: heptachlor, -lindane, -lindane, lindane and arsenic, which come mainly from vegetables, bread and bakery products, milk and dairy products.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86160381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF THE SELENIUM STATUS OF RESIDENTS OF MOLDOVA \u0000BY HAIR","authors":"M. Kapitalchuk, I. Kapitalchuk, N. Golubkina","doi":"10.17816/humeco217703","DOIUrl":"https://doi.org/10.17816/humeco217703","url":null,"abstract":"The purposeof the workwasto assess the selenium status of the hair of Moldovans. \u0000Methods Hair samples were collected from 301 respondents aged 1 to 94 years. The total sample was divided into two parts: female - 192 and male - 109 respondents. Determination of selenium content in hair was carried out by fluorimetric method. \u0000Results The concentrations of selenium in the hair of Moldovan residents in the initial variation series were148-5000g/kg, the interquartile interval was 25-75 centiles and the median (Me) for the total variation series 429-759 (Me=582), for female 406-742 (Me=538) and male 487-798 (Me=631) g/kg. In age groups, the Me value varied from 486 to 703 g/kg. In the samples converted to a normal distribution, the mean values ​​(M) and standard deviations (SD) were 545205 for the general group, 555202 for female, and 628202 g/kg for male. Differences in the average values ​​of selenium concentration in the hair of female and male are statistically significant. In age groups the value of M fluctuated in the range of 541-612 g/kg. \u0000Conclusions. Under the conditions of optimal selenium supply of Moldovan ecosystems, the interquartile range of 2575 centiles of the Se content in the hair of the inhabitants of this country turned out to be higher than that of the inhabitants of the selenium-deficient Orenburg region and the Crimea, at the same time, comparable to the Se content in the hair of the inhabitants of Western Kazakhstan. The average values ​​of Se in the hair of the inhabitants of Moldova are close to the average values ​​in the hair samples from the United States and Canada, where there is a high supply of selenium to the population.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79589224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response of the cardiovascular system to heart rate variability biofeedback in adolescents with different autonomic nervous tone living in northern and southern regions","authors":"D. Demin","doi":"10.17816/humeco321968","DOIUrl":"https://doi.org/10.17816/humeco321968","url":null,"abstract":"BACKGROUND: The reactions of the cardiovascular system of adolescents during self-regulation depend on the state of their initial autonomic tone and region of residence. \u0000AIM: Was to investigate the dynamics of cardiovascular system indices during heart rate variability biofeedback (HRVBF) one-time training in adolescents with different initial autonomic regulation of heart rhythm, taking into account their residence in the northern and southern regions. \u0000MATERIALS AND METHODS: Schoolchildren aged 1617 years, residents of the North-West (n=55), North-East (n=55) and South (n=55) regions of the Russian Federation were examined. Heart rate variability (HRV) and blood pressure (BP) were recorded. Participants were divided into the following groups according to their baseline autonomic regulation of cardiac rhythm: vagotonics, normotonics and sympathotonics. Normotonics and sympathotonics additionally had a one-time HRVBF session due to increase parasympathetic influences on heart rhythm. \u0000RESULTS: The northwestern/northeastern/southern samples revealed 29.1/7.3/16.4% vagotonics; 41.8/47.3/49.1% normotonics; and 29.1/45.4/34.5% sympathotonics. Significantly higher BP levels were detected in sympathotonics in the northeastern region compared to vagotonics and normotonics in this region, as well as sympathotonics in the northwestern and southern regions. HRVBF training was successful in all of its participants, HRV parameters responded significantly more strongly in sympathotonics of the northwest region, while their BP and baroreflex levels were relatively stable. Sympathotonics of the northeastern and southern regions were characterized by preservation of elevated HR after HRVBF, accompanied by a distinct vascular response (significant decrease in BP) and a pronounced baroreflex response. \u0000CONCLUSION: Sympathicotonia and increased vascular response to HRVBF are characteristic of adolescents of the North-West region, who are mostly descendants of immigrants from Southern regions. The descendants of the natives of the northwestern region apparently possess more perfect hereditary mechanisms of cardiovascular system adaptation to the conditions of living in the Arctic.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"141 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75218638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTRACELLULAR LEVEL OF HIF-1α IS AN INFORMATIVE INDICATOR OF THE DELAYED IMPACT OF COVID-19 ON THE METABOLISM OF PERIPHERAL BLOOD LYMPHOCYTES","authors":"O. Zubatkina, L. Dobrodeeva, S. Kruglov","doi":"10.17816/humeco409527","DOIUrl":"https://doi.org/10.17816/humeco409527","url":null,"abstract":"BACKGROUND: COVID-19 infection induces metabolic changes that play a critical role in both SARS-CoV-2 replication and regulation of the immune response. HIF-1, one of the effectors of the PI-3K/Akt/mTOR signal transmission pathway, promotes reprogramming of metabolism through the enhancement of aerobic glycolysis \u0000AIM: To reveal the informativity of the intracellular level of HIF-1 as an indicator of changes in the metabolism of peripheral blood lymphocytes after a COVID-19 infection. \u0000MATERIALS AND METHODS: 59 volunteers were examined, 38 of them did not have a history of COVID-19 and 21 people had the disease 2-8 months before the start of the survey. The presence of IgG antibodies to SARS-CoV-2 was determined in the serum of the blood taken for analysis. The absolute content of lymphocytes was measured in whole blood, and the concentration of HIF-1 was determined in the lymphocyte lysate by enzyme immunoassay. The obtained data was statistically processed using the IBM SPSS software package (version 26). The mean values (M) and standard deviation (SD) were calculated, the normality of distribution was assessed by the Kolmogorov-Smirnov test, the Student's t-test and the level of statistical significance p0.05 were used to compare the means. ROC analysis with the construction of a characteristic curve for the classifier HIF-1 was conducted. \u0000RESULTS: It was found that the content of HIF-1 in peripheral blood lymphocytes in patients after COVID-19 infection is statistically significantly lower compared with those who have not been ill and remains so for 5 months after the disease. The model with the HIF-1 classifier has a high predictive power regarding the likelihood of changes in lymphocyte metabolism after COVID-19 infection. The intracellular content of HIF-1 equal to 1,25 ng/106 cells corresponds to the optimal cut-off threshold. \u0000CONCLUSION: The intracellular level of HIF-1 can be used to assess the likelihood of a delayed impact of COVID-19 on the metabolism of peripheral blood lymphocytes and to monitor metabolic changes.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85091064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat waves, cold spells and excess mortality among population of four cities of the Arctic macroregion","authors":"B. Revich, D. Shaposhnikov","doi":"10.17816/humeco111013","DOIUrl":"https://doi.org/10.17816/humeco111013","url":null,"abstract":"Background: Сlimate warming in Russia is most pronounced in the Arctic macroregion, where it is accompanied by an increase in the frequency and duration of heat waves. This new significant risk factor for population health of the of the largest cities has not yet been sufficiently studied. For the scientific substantiation of plans for adaptation to these phenomen, parameters of such impacts in territories with different types of climate are needed. \u0000Aim: Assessment of excess age-specific mortality during heat waves and cold spells among the urban populations of Arctic macroregion; analysis of differences in the results that might be related to the local climate type from marine to continental. \u0000Methods: A Poisson generalized linear regression of daily mortality counts was used to calculate relative mortality risks during the periods of extreme heat and cold. This model accounted for possibly lagged effects, seasonal and weekly regularity, and long-term trends in mortality. Pearson 2 statistics was used to test the group differences between the heat-related and cold-related effects, as well as site-specific and age-specific differences. \u0000Results: Statistical significance of obtained effect estimates tends to be greater in continental climate than in marine climate. The age group 65 years was more susceptible to the effects of extreme heat and cold than the middle-age group. Cold spells were more harmful to the health of the residents of Murmansk, Archangelsk and Magadan than heat waves, and heat waves were more dangerous in Yakutsk. The greatest values of relative risks were obtained in the age group 65 years: 1,69 (95% CI: 1,342,13) for cerebrovascular disease mortality in Yakutsk during heat waves, and 1,54 (95% CI: 1,182,01) for respiratory disease mortality in Archangelsk during cold spells. \u0000Conclusion: The obtained results can be used by the public health authorities in prevention of additional deaths among the subarctic populations during heat waves and cold spells. \u0000Keywords: Extreme temperature events; heat waves, circumpolar regions; artic, public health; climate change; mortality rates; preventive medicine.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82741365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of short-term speleotherapy exposure on the bioelectric activity of a healthy brain","authors":"V. Semiletova, E. V. Dorohov, Yaroslava V. Bulgakova","doi":"10.17816/humeco192536","DOIUrl":"https://doi.org/10.17816/humeco192536","url":null,"abstract":"BACKGROUND: Speleotherapy is a non-drug therapeutic approach that involves spending time in underground caves or mines with health promotion purpose. However, adaptation mechanisms of the human body and the effects of speleotherapy in healthy brain remain largely unknown. \u0000AIM: To study changes in the functional state of the brain of a healthy person in terms of EEG activity parameters under the speleotherapy exposure. \u0000MATERIALS AND METODS: The study involved a group of 25 student volunteers who were informed about the studys purpose, agreed to participate in the experiment and sighen the informed consent. In the experimental group, EEG registration was carried out before and after a 2-hour speleotherapeutic exposure using the Encephalan-EEGR-19/26 electroencephalograph-recorder. In the control group, EEG was taken before and after a 2-hour rest in a switched off speleological chamber. EEG rhythm ratio indices were calculated as ratios of the power of alpha/theta, alpha/beta1, and (theta + alpha)/beta1 rthythms. Data analysis was carried out using MS Excel and IBM SPSS Statistics v. 26.0 software. \u0000RESULTS: Significant changes in the EEG alpha/theta index in P4, T6 and O2 leads were observed in the experimental group, but not in the control group. The alpha/theta index appeared to be the most sensitive to speleotherapy. No other significant differences between the groups were found. \u0000CONCLUSION: There were no significant differences in the alpha/beta1 and (theta + alpha)/beta1 indices in the subjects undergoing the speleotherapy procedure, while there were significant changes in these indices in O2 derivation in the control group. The alpha/theta index is the most sensitive indicator for assessing the effect of speleotherapy on the healthy human brain.","PeriodicalId":38121,"journal":{"name":"Ekologiya Cheloveka (Human Ecology)","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81900589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}