Chemical Synthesis最新文献_第3页

Immobilized enzymatic alcohol oxidation as a versatile reaction module for multienzyme cascades 作为多酶级联多功能反应模块的固定化酶解酒精氧化技术

Chemical Synthesis Pub Date : 2023-11-27 DOI: 10.20517/cs.2023.40

Kesheng Fu, Lele Dong, Pengbo Liu, Li-Yi Zhou, Guanhua Liu, Jing Gao, Bingjun Gao, Yunting Liu, Yanjun Jiang

{"title":"Immobilized enzymatic alcohol oxidation as a versatile reaction module for multienzyme cascades","authors":"Kesheng Fu, Lele Dong, Pengbo Liu, Li-Yi Zhou, Guanhua Liu, Jing Gao, Bingjun Gao, Yunting Liu, Yanjun Jiang","doi":"10.20517/cs.2023.40","DOIUrl":"https://doi.org/10.20517/cs.2023.40","url":null,"abstract":"Enzymatic alcohol oxidation (EAO) is highly attractive thanks to its efficiency, selectivity, and sustainability benefits, but it is often neglected as a catalytic tool for practical production due to the instability and non-reusability of enzymes. Herein, a non-enantioselective alcohol dehydrogenase engineered from Candida parapsilosis (Cps ADH) and a laccase from Trametes versicolor was immobilized on mesoporous silica nanoflowers (MSNs), fabricating Cps ADH@MSNs (41 U/gsupport) and laccase@MSNs (67 U/gsupport) for EAO, respectively. The structural and functional properties of the MSNs endowed the immobilized enzymes with higher stability than free enzymes, and the relative activity of the immobilized enzyme was 52% and 63%, respectively, after being reused five times. The immobilized enzymes exhibited high activity, selectivity, and complementary substrate specificity in alcohol oxidation. The optimized EAO, as a versatile cascade module, was coupled with several other enzymatic transformations for multi-enzymatic synthesis of high value-added chemicals. The chiral alcohols and amines were produced with 99% ee and 84% to 98% ee, respectively, and (R )-benzoin and 2-furoic acid were prepared with 91% yield, 99% ee and 86% yield, respectively, demonstrating the synthetic utility of the immobilized enzymes.","PeriodicalId":381136,"journal":{"name":"Chemical Synthesis","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proton exchange membrane fuel cells: application for value-added chemical productions 质子交换膜燃料电池：应用于增值化学品生产

Chemical Synthesis Pub Date : 2023-11-27 DOI: 10.20517/cs.2023.44

Xia Jiang, Rui Chen, Yanxin Chen, Canggui Lu

引用次数: 0

A comparative study between Monte Carlo entropic sampling method and local mean field investigations of thermal properties of spin-crossover nanoparticles based on Ising-like model 基于 Ising-like 模型的蒙特卡罗熵采样法与自旋交叉纳米粒子热特性的局部均值场研究对比研究

Chemical Synthesis Pub Date : 2023-11-18 DOI: 10.20517/cs.2023.23

J. Linares, C. Cazelles, Pierre Richard Dahoo, N. Belmouri, K. Boukheddaden

{"title":"A comparative study between Monte Carlo entropic sampling method and local mean field investigations of thermal properties of spin-crossover nanoparticles based on Ising-like model","authors":"J. Linares, C. Cazelles, Pierre Richard Dahoo, N. Belmouri, K. Boukheddaden","doi":"10.20517/cs.2023.23","DOIUrl":"https://doi.org/10.20517/cs.2023.23","url":null,"abstract":"The thermally induced transitions between low-spin (LS) and high-spin (HS) configurations of spin-crossover (SCO) nanoparticles are simulated, focusing on the effects of localized surface and bulk interactions on the average magnetization of 2D square lattices. The thermal behaviors and hysteresis cycles are investigated within the framework of the Ising model Hamiltonian and are conducted following two approaches: local mean field approximation (LMFA) and Monte Carlo entropic sampling (MCES) techniques. The results obtained by these two methods are compared for the two square lattice sizes, 6 $$ times $$ 6 and 7 $$ times $$ 7. Thus, when the bulk-surface interaction term is set to zero, the two approaches lead to identical values of the surface and bulk transition temperatures separated by a long intermediate plateau in both cases. Although hysteresis curves exhibit a similar shape, LMFA shows slightly larger widths $$ Delta T $$ than MCES. On increasing bulk-surface interaction term, the two methods lead to different shifts in equilibrium temperature values for both bulk and surface components, respectively, to lower and higher values by MCES. In general, it is found that LMFA shifts surface equilibrium temperature differently to lower values and enhances the hysteresis effect, particularly for surface molecules. On the other hand, for the 7 $$ times $$ 7 square lattice, the equilibrium temperatures are slightly higher by 1.5% and 3.2% for bulk and surface molecules, respectively, with a narrower hysteresis width in the surface. Moreover, with the MCES method, an abrupt transition instead of a hysteresis transition is calculated for surface molecules ($$ Delta T_{surf}^{MCES}=0 $$ K).","PeriodicalId":381136,"journal":{"name":"Chemical Synthesis","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139261857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual visible-light and NHC-catalyzed radical relay trifunctionalization of unactivated alkenes 未活化烯烃的可见光和 NHC 双催化自由基中继三官能化

Chemical Synthesis Pub Date : 2023-11-17 DOI: 10.20517/cs.2023.43

Jian-Quan Feng, Luning Li, Jingyi Wang, Aoting Ni, Zexuan Wei, Ding Du, Jie Feng

引用次数: 0

Strain engineering of two-dimensional materials for energy storage and conversion applications 用于能量存储和转换应用的二维材料应变工程

Chemical Synthesis Pub Date : 2023-11-03 DOI: 10.20517/cs.2023.34

Xing Peng, Long Chen, Yifan Liu, Chao Liu, Honglan Huang, Jinbo Fan, Pan Xiong, Junwu Zhu

引用次数: 0

The synthesis, characterization and application of the binol-cages of R-/S-enantiomers R-/ s对映体双醇笼的合成、表征及应用

Chemical Synthesis Pub Date : 2023-10-31 DOI: 10.20517/cs.2023.39

Tianyu Li, Luyao Ding, Yihong Kang, Xin-Qi Hao, Yujing Guo, Linlin Shi, Mao-Ping Song