Digital journal of ophthalmology : DJO最新文献_第3页

The crossroads of ocular inflammation and inherited retinal degenerations: a report of two cases. 眼炎症与遗传性视网膜变性的交叉：附两例报告。

Digital journal of ophthalmology : DJO Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2025.04.002

Kirk A J Stephenson, Shanil R Dhanji, Cheryl Y Gregory-Evans, Kevin Gregory-Evans, Kaivon Pakzad-Vaezi

{"title":"The crossroads of ocular inflammation and inherited retinal degenerations: a report of two cases.","authors":"Kirk A J Stephenson, Shanil R Dhanji, Cheryl Y Gregory-Evans, Kevin Gregory-Evans, Kaivon Pakzad-Vaezi","doi":"10.5693/djo.02.2025.04.002","DOIUrl":"10.5693/djo.02.2025.04.002","url":null,"abstract":"We describe the clinical and molecular diagnostic overlap between posterior uveitis and inherited retinal diseases (IRDs) in 2 cases of PRPF31 retinitis pigmentosa (RP) presenting with features of posterior uveitis. Both patients with PRPF31 retinopathy had typical inflammatory clinical features of anterior chamber (AC) cells, vitritis, retinal vasculitis, and cystoid macular edema (CME), which was resistant to carbonic anhydrase inhibitors, systemic steroids, and antimetabolites but eventually responded to intraocular fluocinolone implant. This improvement with local corticosteroids in these RP cases suggests an inflammatory component on top of retinal pigment epithelial pump dysfunction. Aggressive systemic anti-inflammatory/immunosuppressive treatment may cause ocular (eg, cataract, glaucoma) and/or systemic (eg, teratogenic effects, infection risk) morbidity; benefits and risks should be discussed with patients. Bilateral symmetrical reduced vision, nyctalopia, and pigmentary retinopathy in young patients suggests IRD, but significant inflammatory signs may be present and should be addressed. Genetic testing may be helpful in clarifying mixed IRD/uveitis phenotypes, although results must be interpreted cautiously.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 3","pages":"79-85"},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148353809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound biomicroscopy demonstrating pupillary block in near-total hyphema: a case report and implications for surgical planning. 超声生物显微镜显示近全前房积血瞳孔阻滞：一例报告和手术计划的意义。

Digital journal of ophthalmology : DJO Pub Date : 2025-09-28 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2025.01.002

Alexandra N Zdonczyk, Anna Fanghan Yang, Andrew R Lee

引用次数: 0

Effects of digital screen property modification on symptoms of digital eye strain. 数码屏幕属性改变对数码眼疲劳症状的影响。

Digital journal of ophthalmology : DJO Pub Date : 2025-09-28 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2024.04.001

Scott Massa, Sachi A Patil, Leela V Raju

{"title":"Effects of digital screen property modification on symptoms of digital eye strain.","authors":"Scott Massa, Sachi A Patil, Leela V Raju","doi":"10.5693/djo.01.2024.04.001","DOIUrl":"10.5693/djo.01.2024.04.001","url":null,"abstract":"Purpose: To evaluate whether use of digital screen color temperature-modulating software is associated with changes in severity of symptoms associated with digital eye strain.Methods: In this prospective, interventional study, participants were recruited at ophthalmology clinics and via email. Participants completed a pre-intervention survey regarding demographics, digital screen use patterns, and severity of eight digital eye strain symptoms on a five-point Likert scale. Participants were randomized to use color temperature modulating software, reduce digital screen brightness, or change no digital screen properties on their personal computers for 1 month, after which time participants completed a post-intervention survey on digital eye strain symptom severity and adherence to intervention use. Changes in symptom severity scores were assessed using paired t tests.Results: Pre-intervention and post-intervention questionnaires were completed by 47 participants. There was no significant difference in computer screen use times and baseline symptom severity across groups. Regarding usability, 19/19 participants (100%) in the color temperature modulation group and 16/17 (94%) in the brightness reduction group used the intervention half the time or more. In the brightness reduction group, there was a significant reduction in the eye fatigue severity score by 0.82 (P = 0.0007). There was no significant reduction in symptom severity in the color temperature modulation and control groups.Conclusions: In our study cohort, digital screen color temperature modulating software was associated with a high level of usability but was not associated with a reduction in digital eye strain symptom severity.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 3","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148353756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing tolerability and outcomes of cryopreserved and dehydrated amniotic membrane transplantations in the management of corneal disease. 比较冷冻和脱水羊膜移植治疗角膜疾病的耐受性和结果。

Digital journal of ophthalmology : DJO Pub Date : 2025-08-17 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2024.08.001

Ross Tyler Mellman, Hannah Z Weiss, Lama Al Abdul Razzak, Gabrielle Ferguson, Joshua Cohen

{"title":"Comparing tolerability and outcomes of cryopreserved and dehydrated amniotic membrane transplantations in the management of corneal disease.","authors":"Ross Tyler Mellman, Hannah Z Weiss, Lama Al Abdul Razzak, Gabrielle Ferguson, Joshua Cohen","doi":"10.5693/djo.01.2024.08.001","DOIUrl":"10.5693/djo.01.2024.08.001","url":null,"abstract":"Purpose: To investigate the clinical outcomes of dehydrated versus cryopreserved amniotic membrane transplantation for corneal disease.Methods: Clinical data from 56 patients were analyzed retrospectively, including indications for treatment, number of amniotic membrane transplant (AMT) interventions, duration of therapy, use of adjunct medications, visual outcomes, and transplant tolerability. To analyze patient transplant tolerability, medical records were reviewed for relevant keywords at 1 week and 1 month after implantation.Results: A total of 71 AMTs of 56 patients were included. At both follow-up intervals, patients who received a cryopreserved amniotic membrane transplant (CAMT) reported more side effects than did patients who received a dehydrated amniotic membrane transplant (DAMT). Those in the CAMT group also reported greater improvement in vision and a greater feeling of wellness at both intervals compared with patients in the DAMT group. Patients in the DAMT were less likely to require repeat treatments and achieved a higher percent resolution of the primary indication.Conclusions: In our study cohort, cryopreserved amniotic membranes appear to provide greater patient satisfaction, whereas dehydrated membranes appear to provide better clinical outcomes, with less need for repeat treatment. Because of limitations in stratifying disease severity, it cannot be concluded without a prospective cohort trial that the need for repeat treatment is not due to more severe disease in the cryopreserved group.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 3","pages":"54-61"},"PeriodicalIF":0.0,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148353330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 62-year-old woman with periorbital and preseptal edema and erythema. 62岁女性，眼眶周围和鼻中隔水肿及红斑。

Digital journal of ophthalmology : DJO Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI: 10.5693/djo.03.2024.06.006

Ross Mellman, Ali A Mohamed, Fahad Bhullar, Jonathan Berger

引用次数: 0

Association of stage of diabetic retinopathy on intraocular pressure. 糖尿病视网膜病变分期与眼压的关系。

Digital journal of ophthalmology : DJO Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2025.01.001

Chevy Singh, Louis B Cantor

{"title":"Association of stage of diabetic retinopathy on intraocular pressure.","authors":"Chevy Singh, Louis B Cantor","doi":"10.5693/djo.01.2025.01.001","DOIUrl":"10.5693/djo.01.2025.01.001","url":null,"abstract":"Purpose: To determine whether stage of diabetic retinopathy (DR) is associated with increased intraocular pressure (IOP).Methods: The medical records of patients seen in the outpatient ophthalmology clinic at Sidney & Lois Eskenazi Community Hospital in Indianapolis, Indiana, from January 2022 to August 2023 were reviewed retrospectively. The highest IOP of those presenting without type 2 diabetes mellitus (T2DM), T2DM without DR, and varying severity of DR was recorded. Main outcome measures included median and average IOPs recorded from patients who presented without diabetes, diabetes without retinopathy, and mild, moderate, severe nonproliferative and proliferative diabetic retinopathy. Comparisons between groups generated P values, with ≤0.05 indicating statistical significance.Results: A total of 389 patients (759 eyes) were included. Mean patient age was 58. Male patients accounted for 286 eyes (37.7%); Hispanic patients, for 270 eyes (35.6%); patients identifying as black, for 261 eyes (34.4%); white patients, for 195 eyes (25.7%); and Asian patients, for 33 eyes (4.3%). Overall, analysis showed IOP increased between eyes without T2DM compared with mild nonproliferative DR (P = 0.0373), mild DR compared to moderate nonproliferative DR (P = 0.0117), and moderate DR compared with severe nonproliferative DR (P = 0.0001). The IOP observed between severe nonproliferative DR to proliferative DR (P = 0.5351) was not statistically significant.Conclusions: In our study cohort, there was a positive correlation between elevated IOP and more advanced stage of DR, indicating that patients with diabetes but no findings of DR on retinal examination seem to be at greater risk of elevated IOP than those with mild-to-moderate DR. These results suggest that IOP in patients with T2DM, with or without DR, should be closely monitored over time to prevent future IOP-related complications.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 2","pages":"36-45"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analyzing incoming page timestamps to estimate trainee sleep patterns. 分析传入页面的时间戳，以估计学员的睡眠模式。

Digital journal of ophthalmology : DJO Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2025.01.004

Isdin Oke, Steven D Ness, Crandall E Peeler

{"title":"Analyzing incoming page timestamps to estimate trainee sleep patterns.","authors":"Isdin Oke, Steven D Ness, Crandall E Peeler","doi":"10.5693/djo.01.2025.01.004","DOIUrl":"10.5693/djo.01.2025.01.004","url":null,"abstract":"Purpose: Sleep deprivation is highly prevalent among surgical trainees and associated with decreased clinical performance. The goal of this study was to demonstrate a method of analyzing incoming page timestamps to estimate the sleep patterns of trainees during a home-call shift.Methods: This was a retrospective study of all incoming pages to an Ophthalmology Service at a single tertiary care hospital from January 1, 2019, to December 31, 2019. The time and date of each incoming communication was recorded. The Kaplan-Meier estimator was used to determine the cumulative probability of receiving a page over the course of an at-home call shift.Results: The mean number (± standard deviation) of incoming communications received during an overnight home-call shift (5 p.m.-8 a.m.) was 3.5 ± 2.5 (range, 0-15). The median time to first page was 1.4 hours (IQR, 0.4-4.0 hours). There was a significant difference between the number of pages received on weekdays compared to weekends (4.0 ± 2.5 vs 2.3 ± 2.1; P < 0.001). The cumulative probability of receiving a page during a shift was 91.5% (95% CI, 88.1%-95.6%). The probability of a 9-, 8-, 7-, or 6-hour interval without receiving an incoming page was 63.7%, 71.7%, 80.8%, and 87.6%, respectively.Discussion: Analyzing timestamps may serve as a valuable tool for training programs to design home-call schedules that optimize the sleep patterns of trainees and ensure that fatigue does not negatively impact the quality of education and patient care.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 2","pages":"46-49"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Focal choroidal excavation and choroidal neovascular membrane following sildenafil intake. 摄入西地那非后的局灶性脉络膜挖掘和脉络膜新生血管膜。

Digital journal of ophthalmology : DJO Pub Date : 2025-06-08 eCollection Date: 2025-01-01 DOI: 10.5693/djo.03.2024.10.002

Aashul Chawla, Sundaramoorthy Sathishkumar, Dhanashree Ratra

{"title":"Focal choroidal excavation and choroidal neovascular membrane following sildenafil intake.","authors":"Aashul Chawla, Sundaramoorthy Sathishkumar, Dhanashree Ratra","doi":"10.5693/djo.03.2024.10.002","DOIUrl":"10.5693/djo.03.2024.10.002","url":null,"abstract":"Sildenafil citrate is widely abused as a recreational drug. The ocular side effects of this drug are often overlooked, because they tend to be mild and transient. Commonly reported side effects include light sensitivity and dyschromatopsia resulting in impairment of blue-green discrimination. We present a rare occurrence of a focal choroidal excavation (FCE) in a healthy 34-year-old Asian Indian man after sildenafil intake. Sudden diminution of vision was noted a day after taking 50 mg/day sildenafil for 3 consecutive days. An FCE was seen on the optical coherence tomography in the left eye, with visual acuity of 20/30. Choroidal and outer retinal layers were disturbed superior to the fovea. Color vision disturbance was also noted. A choroidal neovascular membrane developed after 8 months, which was treated with ranibizumab injection. Final visual acuity was 20/80, due to macular scarring in the left eye. Sildenafil has been shown to cause choroidal thickening. We hypothesize that the sudden turgescence of the choroid might have led to the FCE.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 2","pages":"50-53"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Periorbital skin hypopigmentation associated with the use of topical glaucoma medications. 眼窝周围皮肤色素沉着与局部青光眼药物的使用有关。

Digital journal of ophthalmology : DJO Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2024.05.001

Sam Karimaghaei, Jeff Yee, Abdelrahman M Elhusseiny

引用次数: 0

Designing a workshop for a temporal artery biopsy simulation. 设计一个模拟颞动脉活检的工作坊。

Digital journal of ophthalmology : DJO Pub Date : 2025-03-19 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2024.07.001

Shahzaib Rehan, Patrick Watts, Ian Williams, Paul Hennessy, Caomhnad O'Flaherty Farrell, Anjana Haridas

{"title":"Designing a workshop for a temporal artery biopsy simulation.","authors":"Shahzaib Rehan, Patrick Watts, Ian Williams, Paul Hennessy, Caomhnad O'Flaherty Farrell, Anjana Haridas","doi":"10.5693/djo.01.2024.07.001","DOIUrl":"https://doi.org/10.5693/djo.01.2024.07.001","url":null,"abstract":"Purpose: To evaluate a wet-lab session designed to teach temporal artery biopsy (TAB) using simulation.Methods: The Welsh Institute for Minimal Access Therapy Team (WIMAT) developed two simulation models using pig ureter for the temporal artery. The session consisted of consultant-led teaching on TAB surgical approaches, mapping the temporal artery with a Doppler device, and practical demonstrations with videos. Trainees performed two biopsies using the models under consultant supervision. Participants completed questionnaires to evaluate their pre- and post-session knowledge, understanding, and learning experiences. Three key areas of comparison were mapping the temporal artery, using an ultrasound doppler device, and performing a TAB.Results: Seven specialist trainees (ST1-5) and 3 staff grade surgeons, supervised by 3 consultants, participated. Paired t test sampling showed statistically significant improvements in mapping the temporal artery (P = 0.0076), using an ultrasound Doppler device (P = 0.0002), and performing a TAB (P = 0.0002). Identified barriers included lack of knowledge, limited prior procedures, concern about damaging the facial nerve, and lack of senior support/supervision, which contributed to trainees' apprehension about performing TAB.Conclusions: This innovative teaching event offers a blueprint for medical training programs to improve TAB training. Modern surgical education benefits from wet labs with expert supervision.","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"31 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0