Research Ethics最新文献

Deficient epistemic virtues and prevalence of epistemic vices as precursors to transgressions in research misconduct 认识论美德的缺失和认识论恶习的盛行是研究不当行为中越轨行为的先兆

IF 1.7

Research Ethics Pub Date : 2024-01-04 DOI: 10.1177/17470161231221258

B. Tang

{"title":"Deficient epistemic virtues and prevalence of epistemic vices as precursors to transgressions in research misconduct","authors":"B. Tang","doi":"10.1177/17470161231221258","DOIUrl":"https://doi.org/10.1177/17470161231221258","url":null,"abstract":"Scientific research is supposed to acquire or generate knowledge, but such a purpose would be severely undermined by instances of research misconduct (RM) and questionable research practices (QRP). RM and QRP are often framed in terms of moral transgressions by individuals (bad apples) whose aberrant acts could be made conducive by shortcomings in regulatory measures of organizations or institutions (bad barrels). This notion presupposes, to an extent, that the erring parties know exactly what they are doing is wrong and morally culpable, but had nonetheless proceeded to commit wrongful acts. However, a confession of intent to deceived is often not readily admitted by perpetrators of RM. I posit that beyond the simplistic notion of conscious moral transgression, deficits in epistemic virtues and/or the prevalence of epistemic vices have important roles to play in initiating and driving RM/QRP. For the individual perpetrator, deficits in epistemic virtues could lead to or amplify errors in one’s desperate attempt to be accomplished or to excel, and pushes one across the ethical line or down the slippery slope of misconduct. Likewise, a lack of epistemic virtue within perpetrators’ institution or organization could make it conducive for deceitful acts and suppress indications and warning signs for the former. Furthermore, epistemic vices exhibited by reviewers, editors and journals could also promote RM/QRP. In this view, epistemic failings, rather than widespread moral deficiencies of individuals within the research ecosystem, may underlie the prevalence of RM/QRP.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"19 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139387379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 human challenge trials and randomized controlled trials: lessons for the next pandemic COVID-19 人类挑战试验和随机对照试验：下一次大流行的经验教训

IF 1.7

Research Ethics Pub Date : 2024-01-03 DOI: 10.1177/17470161231223594

Charles Weijer

{"title":"COVID-19 human challenge trials and randomized controlled trials: lessons for the next pandemic","authors":"Charles Weijer","doi":"10.1177/17470161231223594","DOIUrl":"https://doi.org/10.1177/17470161231223594","url":null,"abstract":"The COVID-19 pandemic touched off an unprecedented search for vaccines and treatments. Without question, the development of vaccines to prevent COVID-19 was an enormous scientific accomplishment. Further, the RECOVERY and Solidarity trials identified effective treatments for COVID-19. But all was not success. The urgent need for COVID-19 prevention and treatment fueled an embrace of risks—to research participants and to the reliability of the science itself—as allegedly necessary costs to speed scientific progress. Scientists and (even) ethicists supported overturning longstanding norms protecting healthy volunteers in human challenge trials to speed vaccine development, but these trials led to no vaccines. Physicians, with the approval of research ethics committees, designed hundreds of unblinded, single-center clinical trials at high risk of bias to speed the identification of new treatments. But these clinical trials led to no treatments. The lesson for future pandemics is that the acceptance of greater risks to participants or science does not reliably lead to progress. We are better served by science that upholds the highest ethical and methodological standards.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"142 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139387473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Needs and preferences of REB members in the development of a new TCPS 2 training program in Canada 在加拿大制定新的 TCPS 2 培训计划时 REB 成员的需求和偏好

IF 1.7

Research Ethics Pub Date : 2023-12-15 DOI: 10.1177/17470161231218173

Jiale Xie, Denise Stockley, Amber Hastings Truelove, Susan Marlin, Rachel Zand, Jennifer Payne, Miranda Miller, Eleftherios K. Soleas

引用次数: 0

Challenges facing Arab researchers in conducting and publishing scientific research: a qualitative interview study 阿拉伯研究人员在开展和发表科学研究方面面临的挑战：定性访谈研究

IF 1.7

Research Ethics Pub Date : 2023-12-13 DOI: 10.1177/17470161231214636

A. Elgamri, Zeinab Mohammed, Karima El-Rhazi, M. Shahrouri, Mamoun Ahram, Al-Mubarak Al-Abbas, Henry Silverman

{"title":"Challenges facing Arab researchers in conducting and publishing scientific research: a qualitative interview study","authors":"A. Elgamri, Zeinab Mohammed, Karima El-Rhazi, M. Shahrouri, Mamoun Ahram, Al-Mubarak Al-Abbas, Henry Silverman","doi":"10.1177/17470161231214636","DOIUrl":"https://doi.org/10.1177/17470161231214636","url":null,"abstract":"Arab researchers encounter formidable obstacles when conducting and publishing their scientific work. We conducted semi-structured interviews with 17 Arab researchers from various Arab Middle East countries to gain a comprehensive understanding of the difficulties they face in research and publication. We analyzed the transcripts using reflexive thematic analysis. Our findings revealed several key challenges. First, Arab researchers struggle to conduct high-quality research due to limited resources, inadequate funding, and a lack of a supportive research infrastructure. Furthermore, a shortage of teamwork and mentoring diminishes research productivity. Perverse promotion policies, heavy teaching loads, and low salaries force many researchers to seek external income sources, leaving them with insufficient time for research. Regarding publishing in high-impact journals, Arab researchers confront challenges existing of insufficient scientific writing skills, underrepresentation on editorial boards, and unconscious biases against researchers from economically challenged areas. Finally, achieving research integrity is closely tied to lack of access to essential resources. To address these issues, our participants proposed targeted interventions at the institutional and external levels. For example, universities can implement mentoring programs, offer workshops on scientific writing and publishing, and foster a supportive institutional culture for research. Addressing the underrepresentation of Arabic researchers on editorial boards is crucial for equity in global scientific publishing. In conclusion, acknowledging and addressing these challenges will empower Arab researchers, elevate research quality, and promote equitable global scientific collaboration. Our findings provide guidance for universities, governments, and international donors seeking to enhance research and publication practices in the Arab Middle East.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"9 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139005400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Passive data collection on Reddit: a practical approach Reddit 上的被动数据收集：实用方法

IF 1.7

Research Ethics Pub Date : 2023-11-28 DOI: 10.1177/17470161231210542

Tiago Rocha-Silva, Conceição Nogueira, Liliana Rodrigues

引用次数: 0

Plagiarism in Higher Education (PLAGiHE) within Sub-Saharan Africa: A systematic review of a decade (2012–2022) literature 撒哈拉以南非洲地区高等教育中的剽窃现象:对十年(2012-2022)文献的系统回顾

IF 1.7

Research Ethics Pub Date : 2023-08-21 DOI: 10.1177/17470161231189646

Dickson Okoree Mireku, Prosper Dzifa Dzamesi, Brandford Bervell

{"title":"Plagiarism in Higher Education (PLAGiHE) within Sub-Saharan Africa: A systematic review of a decade (2012–2022) literature","authors":"Dickson Okoree Mireku, Prosper Dzifa Dzamesi, Brandford Bervell","doi":"10.1177/17470161231189646","DOIUrl":"https://doi.org/10.1177/17470161231189646","url":null,"abstract":"The purpose of this study was to map the distribution of publications on plagiarism among higher educational institutions in sub-Saharan Africa (SSA). Studies reviewed were based on 171 plagiarism related publications within a decade (2012–2022). Findings revealed that most plagiarism related articles were published in 2016. Additionally, a majority of the studies (53) were from Nigeria and Ghana (23). Most of the articles focused on students’ and faculty’s awareness of plagiarism, and institutional prevention of plagiarism, but were rather marginal on challenges involved in preventing plagiarism, as well as effects of plagiarism. Dominant forms of plagiarism were self-plagiarism, branded plagiarism and commission plagiarism. However, major causes of plagiarism comprised easy access to digital information and resources; poor supervision of students; pressure on academics to publish for promotion; and insufficient skills development regarding ethical academic writing. Additionally, plagiarism preventive software and policies on plagiarism were the main ways of preventing plagiarism. Finally, in fighting plagiarism, higher educational institutions in SSA encountered challenges such as lack of well-trained academic experts to detect and report plagiarism cases; reluctance on the part of technical administrative staff to investigate works for traces of plagiarism; and low plagiarism detection skills from project supervisors. Based on the findings, recommendations are made to stakeholders for future research, policy and practice.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"13 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76173787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stakeholders’ experiences of ethical challenges in cluster randomized trials in a limited resource setting: a qualitative analysis 有限资源环境下聚类随机试验中利益相关者的伦理挑战经验:定性分析

IF 1.7

Research Ethics Pub Date : 2023-08-15 DOI: 10.1177/17470161231191247

T. Mtande, C. Lombard, G. Nair, S. Rennie

{"title":"Stakeholders’ experiences of ethical challenges in cluster randomized trials in a limited resource setting: a qualitative analysis","authors":"T. Mtande, C. Lombard, G. Nair, S. Rennie","doi":"10.1177/17470161231191247","DOIUrl":"https://doi.org/10.1177/17470161231191247","url":null,"abstract":"Although the use of the cluster randomized trial (CRT) design to evaluate vaccines, public health interventions or health systems is increasing, the ethical issues posed by the design are not adequately addressed, especially in low- and middle-income country settings (LMICs). To help reveal ethical challenges, qualitative interviews were conducted with key stakeholders experienced in designing and conducting two selected CRTs in Malawi. The 18 interviewed stakeholders included investigators, clinicians, nurses, data management personnel and community workers who were invited to share their experiences related to implementation of CRTs. Data analysis revealed five major themes with ethical implications: (1) The moral obligation for health care providers to participate in health research and its compensation; (2) Suboptimal care services compromising the integrity of CRT; (3) Ensuring scientific validity and withholding care service; (4) Obtaining valid consent and permission for waiver of consent; and (5) Inadequate risk assessment for trial participation. Understanding key ethical issues posed by CRTs in Malawi could improve ethical review and research oversight of this particular study design.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"42 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82220035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Planning a ‘negligible risk’ national health service survey? Counting the cost and strategies for success: a short report 计划进行一项“可忽略风险”的全国卫生服务调查?计算成本和成功的策略:一个简短的报告

IF 1.7

Research Ethics Pub Date : 2023-07-31 DOI: 10.1177/17470161231189602

Laura Cooper, K. Johnston, Marie Williams

引用次数: 0

Defining institutional review board application quality: critical research gaps and future opportunities 定义机构审查委员会申请质量:关键的研究差距和未来的机会

IF 1.7

Research Ethics Pub Date : 2023-07-27 DOI: 10.1177/17470161231187099

Kimberley Serpico

{"title":"Defining institutional review board application quality: critical research gaps and future opportunities","authors":"Kimberley Serpico","doi":"10.1177/17470161231187099","DOIUrl":"https://doi.org/10.1177/17470161231187099","url":null,"abstract":"The quality of a research study application sends a distinct signal to the institutional review board (IRB) about the skills, capacities, preparation, communication, experience, and resources of its authors. However, efforts to research and define IRB application quality have been insufficient. Inattention to the quality of an IRB application is consequential because the application precedes IRB review, and perceptions of quality between the two may be interrelated and interdependent. Without a clear understanding of quality, IRBs do not know how to define quality and researchers do not know how to achieve quality. This position has not been systematically studied to date, and future research could provide much-needed empirical validation. This paper lays the conceptual groundwork for future investigation into what constitutes quality in an IRB application. It includes a landscape review of multidisciplinary research on quality, as well as a discussion of quality frameworks analogous to research with human participants that exist in the published literature. It also examines the background and significance of federal research regulations, regulatory burdens, researchers’ regulatory literacy, and the roles and responsibilities of IRB professionals within this ecosystem.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"374 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75122564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protected from harm, harmed by protection: ethical consequences of the exclusion of pregnant participants from clinical trials 保护免受伤害，被保护伤害:将怀孕参与者排除在临床试验之外的伦理后果

IF 1.7

Research Ethics Pub Date : 2023-07-25 DOI: 10.1177/17470161231189843

R. Zur

{"title":"Protected from harm, harmed by protection: ethical consequences of the exclusion of pregnant participants from clinical trials","authors":"R. Zur","doi":"10.1177/17470161231189843","DOIUrl":"https://doi.org/10.1177/17470161231189843","url":null,"abstract":"Pregnancy is a frequently applied exclusion criteria for many forms of research. Common justifications for this exclusion include the potential for teratogenicity, as well as the potential for physiologic changes in pregnancy to impact the research itself. The systematic exclusion of pregnant persons from clinical studies has created a significant gap in knowledge regarding medication safety and efficacy in pregnancy, which continues to cause significant harm to pregnant persons in need of medical therapy. To produce meaningful data and facilitate effective knowledge translation to the clinical setting, special consideration to the pharmacology of pregnancy, as well as to outcomes of concern for this population is essential. The exclusion of pregnant participants from research is not ethically justifiable, as it violates the principles of autonomy, justice and nonmaleficence. While the inclusion of pregnant patients in research presents it’s own challenges, with appropriate methodological, ethical, and clinical considerations, we may be able to narrow the knowledge gap and improve drug availability and safety for pregnant patients and their children.","PeriodicalId":38096,"journal":{"name":"Research Ethics","volume":"21 1","pages":"536 - 545"},"PeriodicalIF":1.7,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73739519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0