IJC Heart and Vasculature最新文献

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Long-term cardiovascular outcomes after percutaneous coronary intervention in patients with systemic sclerosis
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-04 DOI: 10.1016/j.ijcha.2025.101625
Kazutoshi Hirose , Hiroyuki Kiriyama , Shun Minatsuki , Yugo Nagae , Tatsuki Furusawa , Takashi Hiruma , Atsushi Kobayashi , Masataka Sato , Shinnosuke Sawano , Tatsuya Kamon , Hiroki Shinohara , Mizuki Miura , Akihito Saito , Satoshi Kodera , Junichi Ishida , Norifumi Takeda , Hiroyuki Morita , Issei Komuro , Norihiko Takeda
{"title":"Long-term cardiovascular outcomes after percutaneous coronary intervention in patients with systemic sclerosis","authors":"Kazutoshi Hirose ,&nbsp;Hiroyuki Kiriyama ,&nbsp;Shun Minatsuki ,&nbsp;Yugo Nagae ,&nbsp;Tatsuki Furusawa ,&nbsp;Takashi Hiruma ,&nbsp;Atsushi Kobayashi ,&nbsp;Masataka Sato ,&nbsp;Shinnosuke Sawano ,&nbsp;Tatsuya Kamon ,&nbsp;Hiroki Shinohara ,&nbsp;Mizuki Miura ,&nbsp;Akihito Saito ,&nbsp;Satoshi Kodera ,&nbsp;Junichi Ishida ,&nbsp;Norifumi Takeda ,&nbsp;Hiroyuki Morita ,&nbsp;Issei Komuro ,&nbsp;Norihiko Takeda","doi":"10.1016/j.ijcha.2025.101625","DOIUrl":"10.1016/j.ijcha.2025.101625","url":null,"abstract":"<div><h3>Background</h3><div>Recent data have shown that systemic sclerosis (SSc) is a significant risk factor for coronary artery disease (CAD) and poorer cardiovascular outcomes in the setting of acute coronary syndrome. However, the morphological characteristics of CAD and the long-term cardiovascular outcomes in patients with concurrent SSc and CAD remain unclear.</div></div><div><h3>Methods</h3><div>We retrospectively investigated 3,300 patients with CAD who underwent percutaneous coronary intervention (PCI) without prior myocardial infarction or coronary artery revascularization. Laboratory, echocardiographic and angiographic characteristics, and clinical outcomes were compared between patients with and without SSc according to a 1:3 propensity score-matching analysis adjusted for patient demographics and comorbidities. The primary outcome was a composite of cardiac death, myocardial infarction, and stroke, and the secondary outcome was a composite of the primary outcome and heart failure hospitalization.</div></div><div><h3>Results</h3><div>Among all 3,300 patients, 17 (0.5 %) had SSc. The patients were classified into an SSc group (n = 17) and non-SSc group (n = 51) by propensity score matching. There were no significant differences in laboratory or echocardiographic parameters between the two groups. However, CAD tended to be more complex in the SSc group because of the higher proportion of left main trunk lesions (p = 0.100) and higher SYNergy between PCI with TAXUS™ and Cardiac Surgery (SYNTAX) score (p = 0.030). During a median follow-up of 3.1 years, patients with SSc more frequently experienced primary and secondary outcomes than those without SSc (both log-rank p &lt; 0.02).</div></div><div><h3>Conclusions</h3><div>Among patients with CAD, long-term cardiovascular outcomes after PCI were poorer in those with than without SSc.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"57 ","pages":"Article 101625"},"PeriodicalIF":2.5,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter versus surgical aortic valve replacement in patients with aortic stenosis with a small aortic annulus: A meta-analysis with reconstructed time to event data 经导管与手术主动脉瓣置换术治疗伴有小主动脉环的主动脉狭窄患者:一项具有重建时间到事件数据的meta分析。
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2024.101578
Ahmed K. Awad , Zina Otmani , Mazen Negmeldin Aly Yassin , Ahmed Mazen Amin , Farouq Bahaa Alahmed , Zineddine Belabaci , Haya A. Hegazy , Unaiza Ahmad , Mohamed Abuelazm
{"title":"Transcatheter versus surgical aortic valve replacement in patients with aortic stenosis with a small aortic annulus: A meta-analysis with reconstructed time to event data","authors":"Ahmed K. Awad ,&nbsp;Zina Otmani ,&nbsp;Mazen Negmeldin Aly Yassin ,&nbsp;Ahmed Mazen Amin ,&nbsp;Farouq Bahaa Alahmed ,&nbsp;Zineddine Belabaci ,&nbsp;Haya A. Hegazy ,&nbsp;Unaiza Ahmad ,&nbsp;Mohamed Abuelazm","doi":"10.1016/j.ijcha.2024.101578","DOIUrl":"10.1016/j.ijcha.2024.101578","url":null,"abstract":"<div><h3>Background</h3><div>Aortic stenosis (AS) remains a prevalent and serious global health concern, exacerbated by an aging population worldwide. This valvular disease, when symptomatic and without appropriate intervention, severe AS can drastically reduce life expectancy. In our systematic review and <em>meta</em>-analysis, we aim to synthesize available evidence to guide clinical decision-making by comparing the performance of TAVR and SAVR, specifically in patients with severe AS and a small aortic annulus.</div></div><div><h3>Methods</h3><div>We searched PubMed, EMBASE, Cochrane, Web of Science, and Scopus from inception till May 2024. The risk ratio (RR) and mean difference (MD) with a 95 % confidence interval (CI) are provided as effect size estimates, with all analyses being conducted using RevMan 5.4.</div></div><div><h3>Results</h3><div>Eleven studies with 3,670 patients were included. TAVR significantly increased the risk of 2-year new permanent pacemaker implantation (PPI) (RR = 2.42; 95 % CI: [1.70–3.44], P &lt; 0.0001) and major vascular complications (RR = 3.73; 95 % CI: [1.98–6.99], P &lt; 0.0001) than SAVR. However, TAVR significantly decreased the risk of patient-prosthesis mismatch (PPM) (RR = 0.56; 95 % CI: [0.48–0.65], P &lt; 0.00001) and new-onset atrial fibrillation (AF) (RR = 0.31; 95 % CI: [0.23–0.41], P &lt; 0.00001). Also, SAVR reduced the risk of paravalvular leak (PVL) (RR = 3.35; 95 % CI: [1.79–6.27], P = 0.0002).</div></div><div><h3>Conclusion</h3><div>TAVR had a significantly reduced risk of PPM and new-onset AF but with increased PPI and vascular complications. Also, TAVR significantly improved EOA and iEOA. Furthermore, SAVR had less risk of PVL, and better LVEF improvement at predischarge. Therefore, TAVR and SAVR remain valid alternatives, and decisions should be based on anatomy of the annulus and aortic root,operative risk, and comorbidities.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101578"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial fibrillation does not equal atrial fibrillation: The important prognostic implications of new-onset atrial fibrillation 心房颤动不等于心房颤动:新发心房颤动的重要预后意义。
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2024.101572
Andreas Goette, Raffaele De Caterina, Joris R. de Groot, Dobromir Dobrev
{"title":"Atrial fibrillation does not equal atrial fibrillation: The important prognostic implications of new-onset atrial fibrillation","authors":"Andreas Goette,&nbsp;Raffaele De Caterina,&nbsp;Joris R. de Groot,&nbsp;Dobromir Dobrev","doi":"10.1016/j.ijcha.2024.101572","DOIUrl":"10.1016/j.ijcha.2024.101572","url":null,"abstract":"","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101572"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The inflammatory and nutritional status in patients with dilated cardiomyopathy: Different impact for distinct phenogroups?
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2025.101610
Tobias Lerchner , Anke Fender , Dobromir Dobrev , Tienush Rassaf , Lars Michel
{"title":"The inflammatory and nutritional status in patients with dilated cardiomyopathy: Different impact for distinct phenogroups?","authors":"Tobias Lerchner ,&nbsp;Anke Fender ,&nbsp;Dobromir Dobrev ,&nbsp;Tienush Rassaf ,&nbsp;Lars Michel","doi":"10.1016/j.ijcha.2025.101610","DOIUrl":"10.1016/j.ijcha.2025.101610","url":null,"abstract":"","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101610"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining D-dimer and LDL/HDL ratio to predict the absence of atrial fibrillation in patients with an Implantable Loop Recorder for embolic stroke of Undetermined source
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2025.101611
Kosuke Yoshikawa , Taku Asano , Yoshimi Onishi , Yuki Takai , Hiroto Sugiyama , Shuhei Arai , Toshihiko Gokan , Yuya Nakamura , Koichiro Inokuchi , Miwa Kikuchi , Tatsuya Onuki , Hitoshi Ezumi , Shinji Koba , Kaoru Tanno , Youichi Kobayashi , Toshiro Shinke
{"title":"Combining D-dimer and LDL/HDL ratio to predict the absence of atrial fibrillation in patients with an Implantable Loop Recorder for embolic stroke of Undetermined source","authors":"Kosuke Yoshikawa ,&nbsp;Taku Asano ,&nbsp;Yoshimi Onishi ,&nbsp;Yuki Takai ,&nbsp;Hiroto Sugiyama ,&nbsp;Shuhei Arai ,&nbsp;Toshihiko Gokan ,&nbsp;Yuya Nakamura ,&nbsp;Koichiro Inokuchi ,&nbsp;Miwa Kikuchi ,&nbsp;Tatsuya Onuki ,&nbsp;Hitoshi Ezumi ,&nbsp;Shinji Koba ,&nbsp;Kaoru Tanno ,&nbsp;Youichi Kobayashi ,&nbsp;Toshiro Shinke","doi":"10.1016/j.ijcha.2025.101611","DOIUrl":"10.1016/j.ijcha.2025.101611","url":null,"abstract":"<div><h3>Background and Objective</h3><div>Embolic stroke of undetermined source (ESUS) patients undergoing long-term rhythm monitoring with Implantable Loop Recorder (ILR) have an atrial fibrillation (AF) detection rate of approximately 12 % at 1 year and 30 % with extended follow-up over 3 years. However, research specifically focusing on the majority of patients in whom AF is not detected through implantable cardiac monitors remains limited. Abnormal lipid profiles may be associated with embolic risks from non-AF sources. This study aimed to develop a model to predict the absence of AF in patients with ESUS using multiple variables, including lipid profiles.</div></div><div><h3>Methods</h3><div>A retrospective, multicenter cohort study was conducted across four institutions, involving 99 ESUS patients. Patients were categorized based on AF detection via ILR. Patient characteristics, blood test results, and echocardiographic findings were assessed through univariate and multivariate logistic regression analyses. ROC curve analysis was performed to evaluate the biomarkers’ predictive accuracy.</div></div><div><h3>Results</h3><div>AF was detected in 30.3 % of patients over a median follow-up of 25.5 months. Multivariate analysis confirmed elevated D-dimer (OR: 2.77, p = 0.002), low LDL/HDL ratio (OR: 2.0, p = 0.01), and CHA2DS2-VASc score (OR: 1.4, p = 0.04) as independent predictors of AF detection. The CHA2DS2-VASc score was excluded due to multicollinearity, and patients with D-dimer &lt; 0.9 μg/ml and LDL/HDL ratio &gt; 1.98 had significantly lower AF detection rates (6.8 %, P &lt; 0.001; sensitivity 93.1 %, specificity 44.2 %).</div></div><div><h3>Conclusion</h3><div>Combining D-dimer and LDL/HDL ratios provides an effective and accessible method for predicting the absence of AF in patients with an ILR for ESUS.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101611"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic valve replacement in uncontrolled diabetes: a matter of causes – effect
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2025.101616
Luca Scorpiglione, Gino Duronio, Marco Zimarino
{"title":"Aortic valve replacement in uncontrolled diabetes: a matter of causes – effect","authors":"Luca Scorpiglione,&nbsp;Gino Duronio,&nbsp;Marco Zimarino","doi":"10.1016/j.ijcha.2025.101616","DOIUrl":"10.1016/j.ijcha.2025.101616","url":null,"abstract":"","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101616"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of TIMI risk score combined with systemic immune-inflammation index and lipoprotein(a) in patients with ST-Segment elevation myocardial infarction after percutaneous coronary intervention
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2025.101599
Yuankun Gu , Yu Zhang , Deshan Yao , Hui Shen , Xin Pan , Kaizheng Gong
{"title":"Prognostic value of TIMI risk score combined with systemic immune-inflammation index and lipoprotein(a) in patients with ST-Segment elevation myocardial infarction after percutaneous coronary intervention","authors":"Yuankun Gu ,&nbsp;Yu Zhang ,&nbsp;Deshan Yao ,&nbsp;Hui Shen ,&nbsp;Xin Pan ,&nbsp;Kaizheng Gong","doi":"10.1016/j.ijcha.2025.101599","DOIUrl":"10.1016/j.ijcha.2025.101599","url":null,"abstract":"<div><h3>Background</h3><div>Thrombolysis in Myocardial Infarction (TIMI) risk score in patients with ST-segment elevation myocardial infarction (STEMI) is associated with major adverse cardiovascular events (MACE). This study aimed to develop a prediction model based on the TIMI risk score for MACE in STEMI patients after percutaneous coronary intervention (PCI).</div></div><div><h3>Methods</h3><div>We conducted a retrospective data analysis on 290 acute STEMI patients admitted to the Affiliated Hospital of Yangzhou University from January 2022 to June 2023 and met the inclusion criteria. The primary endpoint was the occurrence of MACE. Multivariate logistic regression was used to identify independent predictors that could predict the likelihood of MACE, and R software was utilized to construct and validate the prediction model.</div></div><div><h3>Results</h3><div>Systemic immune-inflammation index (SII), lipoprotein(a) [Lp(a)], and TIMI risk score were identified as independent risk factors for MACE in STEMI patients (p &lt; 0.05). A nomogram was constructed based on these factors. The area under the receiver operating characteristic curve values for the training and validation sets were 0.883 (95 % CI: 0.836–0.930) and 0.841 (95 % CI: 0.756–0.925), respectively. The calibration curves displayed a high consistency between prediction and observation in the training and validation sets. Additionally, decision curve analysis (DCA) demonstrated the clinical usefulness of the nomogram.</div></div><div><h3>Conclusions</h3><div>SII, Lp(a), and TIMI risk score are independent risk factors for MACE within one year in STEMI patients after PCI. Incorporating SII and Lp(a) into the TIMI risk score enhances the predictive value for adverse outcomes, thereby supporting healthcare professionals in clinical decision-making.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101599"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous echo contrast in the left atrial appendage is linked to a higher risk of thromboembolic events and mortality in patients with atrial fibrillation 心房颤动患者左心耳自发性回声造影与血栓栓塞事件和死亡率增高有关。
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2024.101590
Jan Traub , David Hettesheimer , Jule Pinter , Floran Sahiti , Georg Fette , Carsten Henneges , Caroline Morbach , Sebastian Herrmann , Frank Puppe , Anna Frey , Stefan Störk , Martin Christa
{"title":"Spontaneous echo contrast in the left atrial appendage is linked to a higher risk of thromboembolic events and mortality in patients with atrial fibrillation","authors":"Jan Traub ,&nbsp;David Hettesheimer ,&nbsp;Jule Pinter ,&nbsp;Floran Sahiti ,&nbsp;Georg Fette ,&nbsp;Carsten Henneges ,&nbsp;Caroline Morbach ,&nbsp;Sebastian Herrmann ,&nbsp;Frank Puppe ,&nbsp;Anna Frey ,&nbsp;Stefan Störk ,&nbsp;Martin Christa","doi":"10.1016/j.ijcha.2024.101590","DOIUrl":"10.1016/j.ijcha.2024.101590","url":null,"abstract":"<div><h3>Background</h3><div>Cardioversion, a rhythm control treatment for atrial fibrillation (AF), requires ruling out cardiac embolic sources, often originating from the left atrial appendage (LAA). Transesophageal echocardiography (TEE) is used for LAA evaluation, but it is invasive and not widely available. This study aimed to identify cardiovascular risk factors linked to LAA abnormalities and predictors of thromboembolic events and all-cause mortality.</div></div><div><h3>Methods</h3><div>A single-center retrospective analysis included AF patients admitted to the University Hospital Würzburg between 2009 and 2018 undergoing TEE.</div></div><div><h3>Results</h3><div>Among 2400 AF patients (median age 72; 36 % women), 469 (20 %) had LAA abnormalities: 282 (60 %) had spontaneous echo contrast (SEC), 72 (15 %) had thrombus formation (THR), and 115 (25 %) had both. Predictors of LAA abnormalities included age (OR 1.04; p = 0.002), congestive heart failure (OR 1.70; p = 0.009), diabetes (OR 1.74; p = 0.007), stroke history (OR 3.36; p = 0.001), vascular disease (OR 1.57; p = 0.026), elevated alkaline phosphatase (OR 1.15; p = 0.003), prior VKA intake (OR 1.53; p = 0.002), and DOAC intake (OR 0.57; p = 0.038). SEC with or without THR independently predicted thromboembolic events (HR 1.74, p = 0.031 and HR 1.53, p = 0.006) and all-cause mortality (HR 1.77, p = 0.011 and HR 1.57, p = 0.002), adjusted for cardiovascular risk factors, anticoagulation, and laboratory data.</div></div><div><h3>Conclusions</h3><div>In AF patients undergoing TEE, SEC, often overlooked in cardioversion decisions, independently predicted thromboembolic events and mortality.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101590"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycemic control after aortic valve replacement: A retrospective study
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2024.101596
Yuval Avidan , Amir Aker , Ibrahim Naoum , Nili Stein , Sameer Kassem
{"title":"Glycemic control after aortic valve replacement: A retrospective study","authors":"Yuval Avidan ,&nbsp;Amir Aker ,&nbsp;Ibrahim Naoum ,&nbsp;Nili Stein ,&nbsp;Sameer Kassem","doi":"10.1016/j.ijcha.2024.101596","DOIUrl":"10.1016/j.ijcha.2024.101596","url":null,"abstract":"<div><h3>Background</h3><div>Aortic stenosis (AS) is treated through transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR), with diabetes being prevalent among these patients. Inflammation participates in the pathogenesis of AS, and emerging evidence suggests that TAVI may exert anti-inflammatory effects. Given the established link between diabetes and inflammation, we sought to evaluate the impact of aortic valve replacement (AVR) on glycemic control.</div></div><div><h3>Methods</h3><div>Data from 10,129 consecutive patients undergoing either TAVI or SAVR between January 2010 and January 2022 were analyzed. Of these, 3,783 with diabetes had available pre- and post-procedural glycated hemoglobin (HbA1c) measurements. Analysis of 1,284 individuals with HbA1c ≥ 7 % was conducted. Propensity-score matching produced two well-matched cohorts of 266 TAVI and SAVR patients, enabling comparison of periprocedural HbA1c.</div></div><div><h3>Results</h3><div>In the total cohort (n = 1,284), HbA1c decreased from 8.15 ± 1.12 to 7.88 ± 1.38 (p &lt; 0.001). After matching, the TAVI group showed a significant reduction from 8.31 ± 1.31 to 7.86 ± 1.56 (p &lt; 0.001), while a modest decrease from 8.33 ± 1.33 to 8.15 ± 1.61 (p = 0.046) was observed in SAVR group. The TAVI group showed a trend toward a greater percentage change in HbA1c (p = 0.051). Clinically meaningful improvement in HbA1c (≥ 0.3 %) was similar between TAVI (53.1 %) and SAVR (45.6 %) patients (OR = 1.34, 95 % CI 0.93–1.95).</div></div><div><h3>Conclusions</h3><div>Management of AS through either intervention improved post-procedural glycemia in patients with uncontrolled diabetes. The extent of glycemic improvement was more pronounced with TAVI. Further investigations through controlled and prospective studies could provide more conclusive insights into this matter.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101596"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in the application of cardiac magnetic resonance to predict recurrence of atrial fibrillation after catheter ablation: A systematic review and meta-analysis
IF 2.5
IJC Heart and Vasculature Pub Date : 2025-02-01 DOI: 10.1016/j.ijcha.2025.101603
Cuncun Yu , zhenjuan Liu , shiyu Zhu
{"title":"Progress in the application of cardiac magnetic resonance to predict recurrence of atrial fibrillation after catheter ablation: A systematic review and meta-analysis","authors":"Cuncun Yu ,&nbsp;zhenjuan Liu ,&nbsp;shiyu Zhu","doi":"10.1016/j.ijcha.2025.101603","DOIUrl":"10.1016/j.ijcha.2025.101603","url":null,"abstract":"<div><h3>Background</h3><div>This systematic review and <em>meta</em>-analysis aimed to assess changes in left atrial structure and function at baseline and after catheter ablation and their association with atrial fibrillation recurrence using cardiac magnetic resonance imaging (MRI).</div></div><div><h3>Methods</h3><div>As of June 2024, a total of 3086 articles have been obtained through searching PubMed, Embase, and Cochrane databases. Standard mean differences and 95% confidence intervals were used to examine structural and functional changes of left atrium after catheter ablation and their relationship with recurrence of atrial fibrillation.</div></div><div><h3>Results</h3><div>A total of 13 prospective cohort studies were included in the analysis. Decreased left atrial emptying capacity is seen in the short term after catheter ablation, and structural changes in the left atrium are seen in the long term (EFActive: SMD, 1.23, 95 % CI, 1.10–2.36, p &lt; 0.05; EFTotal: SMD, 0.83, 95 % CI, 0.02–1.64, p &lt; 0.05; MinLAV: SMD, 0.30, 95 % CI, 0.01–0.59, p &lt; 0.05). Decrease in left atrial volume after catheter ablationis positively associated with the risk of recurrence of atrial fibrillation. (MaxLAV: SMD, 1.27, 95 % CI, 0.05, 2.49, p &lt; 0.05; MaxLAVi: SMD, 0.48, 95 % CI, 0.05,0.9, p &lt; 0.05;MinLAVi: SMD, 0.78, 95 % CI, 0.39,1.16, p &lt; 0.05). The larger the left atrial volume and the lower the emptying and strain function, the greater the likelihood of recurrence of atrial fibrillation following catheter ablation, (MaxLAV: SMD, 0.38, 95 % CI, 0.18,0.59, p &lt; 0.05;MinLAV: SMD, 0.83,95 % CI, 0.41,1.24, p &lt; 0.05; MaxLAVi: SMD, 0.35, 95 % CI, 0.21,0.50, p &lt; 0.05;MinLAVi: SMD, 0.62, 95 % CI, 0.47,0.78, p &lt; 0.05; EFPassive: SMD, −0.57, 95 % CI, −0.78, −0.37, p &lt; 0.05; EFActive: SMD, −0.62, 95 % CI, −1.08, −0.15, P &lt; 0.05; EFTotal: SMD, −0.70, 95 % CI, −0.97, −0.44, P &lt; 0.05; ℇCT: SMD, −0.61, 95 % CI, −0.90, −0.32, p &lt; 0.05; PLAS: SMD, −1.22, 95 % CI, −1.87, −0.57, p &lt; 0.05; ℇR: SMD, −0.50, 95 % CI, −0.79, −0.21, p &lt; 0.05; PLAS: SMD, −1.22, 95 % CI, −1.87, −0.57, p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Short-term left atrial functional impairment can be observed after catheter ablation, while long-term reduction in left atrial volume can be seen. Changes in left atrial volume are likely to lead to the recurrence of atrial fibrillation, while alterations in left atrial function help maintain sinus rhythm. Larger left atrial volume and lower emptying and strain function at baseline assessment by cardiac magnetic resonance are more likely to lead to recurrence of atrial fibrillation after catheter ablation, which may be useful to identify those for whom catheter ablation has reduced success or for whom more aggressive ablation or medications may be useful.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"56 ","pages":"Article 101603"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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