高血压糖尿病患者踝肱指数与颈股脉波速度的关系

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

IJC Heart and Vasculature Pub Date : 2025-07-28 DOI:10.1016/j.ijcha.2025.101761

Jinbo Liu , Xuechen Cui , Shantong Jiang , Jin Wang , Huan Wen , Kun Xiong , Hongwei Zhao , Na Zhao , Hongyu Wang

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引用次数: 0

摘要

踝肱指数（踝肱指数，ABI）用于外周动脉疾病的诊断。动脉硬度可通过颈-股脉波速度（CF-PWV）测量。本研究旨在探讨高血压合并糖尿病患者ABI与CF-PWV的关系。方法选取我院血管内科1577例患者（M/F 812/765）。ABI由VaseraVS-1000血管筛选系统（Fukuda Denshi, Tokyo, Japan）记录。CF-PWV用Complior仪记录。结果合并糖尿病的高血压患者scf - pwv显著高于无糖尿病的高血压患者(13.77±3.91 vs 11.83±3.26 m/s, p <；0.05)。合并糖尿病的高血压患者右ABI明显低于无糖尿病的高血压患者(1.062±0.163 vs 1.102±0.105,p <；0.05)。整个研究组右ABI与年龄、收缩压、CF-PWV、肌酐呈负相关(r = - 0.081, p = 0.001；r =−0.069,p <；0.001;R = - 0.178, p <；0.001;R = - 0.124, p <；分别为0.001)。多元线性回归发现，CF-PWV、体重指数（BMI）、性别、肌酐、总胆固醇、尿酸和糖尿病是所有患者RABI的独立相关因素(β = - 0.168, p <；0.001;β = 0.180, p <；0.001;β = - 0.189, p <；0.001;β = - 0.102, p = 0.008；β = 0.088, p = 0.004；β = - 0.100, p = 0.009;β = - 0.062, p = 0.043；分别)。CF-PWV、BMI、性别和HDL-C是所有患者左ABI的独立相关因素(β = - 0.170, p <；0.001;β = 0.172, p <；0.001;β = - 0.104, p = 0.001；β = 0.074, p = 0.023；分别)。结论高血压糖尿病患者sabi明显降低，CF-PWV升高。CF-PWV是ABI的独立相关因素，表明大动脉弹性越大，下肢动脉闭塞的概率越高。

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Relationship between ankle brachial index and carotid-femoral pulse wave velocity in hypertension patients with diabetes mellitus

Background

Ankle-brachial index (ABI) is used to diagnose peripheral artery disease. Arterial stiffness could be measured by carotid-femoral pulse wave velocity (CF-PWV). The study was to investigate relationship between ABI and CF-PWV in patients with hypertension and diabetes mellitus.

Methods

1577 patients (M/F 812/765) from Department of Vascular Medicine were enrolled. ABI was recorded by VaseraVS-1000 vascular screening system (Fukuda Denshi, Tokyo, Japan). CF-PWV was recorded by Complior apparatus.

Results

CF-PWV was significantly higher in hypertension patients with diabetes mellitus than hypertension patients without diabetes mellitus (13.77 ± 3.91 vs 11.83 ± 3.26 m/s, p < 0.05). Right ABI was significantly lower in hypertension patients with diabetes mellitus than hypertension patients without diabetes mellitus (1.062 ± 0.163 vs 1.102 ± 0.105, p < 0.05). Right ABI was negatively correlated with age, systolic blood pressure, CF-PWV and creatinine in entire study group (r = −0.081, p = 0.001; r = −0.069,p < 0.001; r = −0.178, p < 0.001; r = −0.124, p < 0.001, respectively). Multiple linear regressions found that CF-PWV, body mass index (BMI), gender, creatinine, total cholesterol, uric acid and diabetes mellitus were independent associating factors of RABI in all patients (β = −0.168, p < 0.001; β = 0.180, p < 0.001; β = −0.189, p < 0.001; β = −0.102, p = 0.008; β = 0.088, p = 0.004; β = −0.100, p = 0.009;β = −0.062, p = 0.043; respectively). CF-PWV, BMI, gender and HDL-C were independent associating factors of left ABI in all patients (β = −0.170, p < 0.001; β = 0.172, p < 0.001; β = −0.104, p = 0.001; β = 0.074, p = 0.023; respectively).

Conclusions

ABI was significantly lower in hypertension patients with diabetes mellitus, with higher level of CF-PWV. CF-PWV was an independent associating factor of ABI, indicating the greater the elasticity of the large arteries, the higher the probability of lower limb artery occlusion.

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来源期刊

IJC Heart and Vasculature Medicine-Cardiology and Cardiovascular Medicine

CiteScore

4.90

自引率

10.30%

发文量

216

审稿时长

56 days

期刊介绍： IJC Heart & Vasculature is an online-only, open-access journal dedicated to publishing original articles and reviews (also Editorials and Letters to the Editor) which report on structural and functional cardiovascular pathology, with an emphasis on imaging and disease pathophysiology. Articles must be authentic, educational, clinically relevant, and original in their content and scientific approach. IJC Heart & Vasculature requires the highest standards of scientific integrity in order to promote reliable, reproducible and verifiable research findings. All authors are advised to consult the Principles of Ethical Publishing in the International Journal of Cardiology before submitting a manuscript. Submission of a manuscript to this journal gives the publisher the right to publish that paper if it is accepted. Manuscripts may be edited to improve clarity and expression.