Recurrences of the infective endocarditis: clinical features and outcomes. Results from the Polish infective endocarditis registry (POL-ENDO)

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

IJC Heart and Vasculature Pub Date : 2025-07-28 DOI:10.1016/j.ijcha.2025.101743

Jakub W. Orzech , Karina Zatorska , Maciej Grabowski , Małgorzata Misztal-Ogonowska , Dagmara B. Orzech , Ilona Kowalik , Katarzyna Kurnicka , Magdalena Potapowicz-Krysztofiak , Edyta Płońska-Gościniak , Mariusz Gąsior , Tomasz Hryniewiecki

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引用次数: 0

Abstract

Background

Patients with prior infective endocarditis are associated with an increased risk of recurrence.

Aims

This study aimed to assess the clinical profile and treatment results of recurrent IE patients in Poland and compare them to European recurrent IE profile.

Methods

A prospective multicenter observational cohort study of recurrent IE and first-episode IE patients from 160 medical centers in Poland registered between August 2022 and August 2024 was conducted. Polish recurrent IE cases were compared with those recorded in the ESC-EORP EURO-ENDO registry.

Results

Of a total of 1758 IE patients, recurrent IE patients (n = 371) were younger than first-episode IE (n = 1387) patients [58.2 ± 16.6 vs. 62.6 ± 16.2, p < 0.001] and predominated in Poland [21.1 % vs. 8.6 %, p < 0.001]. Dental treatment predisposed to IE recurrence [12.8 % vs. 5.5 %, p < 0.001]. Prosthetic valve IE predominated among recurrent IE patients [33.1 % vs. 19.7 %, p < 0.001]. Fever > 38° was observed less often among recurrent IE cases [34.8 % vs. 54.1 %, p < 0.001]. Negative blood culture predominated among recurrent IE cases [43.3 % vs. 27.2 %, p < 0.001]. Polish recurrent IE patients were rarely operated than European counterparts [55.2 % vs. 64.8 %, p = 0.032]. The embolic surgery indications were less prominent in Poland [0.08 % vs. 20.2 %, p < 0.001].

Conclusions

The IE recurrence rate in Poland is greater. Dental treatment and valve prosthesis predispose to recurrence of IE. Fever > 38° is less often observed among recurrent IE. Surgical treatment is underutilized among Polish recurrent IE patients. Embolic and uncontrolled infection indications for surgery was underrated in Poland. The IE recurrence is not associated with increased in-hospital mortality.

查看原文本刊更多论文

感染性心内膜炎的复发：临床特征和结果。波兰感染性心内膜炎登记（POL-ENDO）结果

背景：既往患有感染性心内膜炎的患者与复发风险增加相关。目的：本研究旨在评估波兰IE复发患者的临床概况和治疗结果，并将其与欧洲IE复发概况进行比较。方法对波兰160个医疗中心于2022年8月至2024年8月登记的复发性IE和首发IE患者进行前瞻性多中心观察队列研究。将波兰复发性IE病例与ESC-EORP EURO-ENDO登记处记录的病例进行比较。结果在1758例IE患者中，复发IE患者（n = 371）比首发IE患者（n = 1387）年轻[58.2±16.6∶62.6±16.2,p <；0.001]在波兰占主导地位[21.1%对8.6%,p <；0.001]。牙科治疗易导致IE复发[12.8% vs. 5.5%, p <；0.001]。人工瓣膜IE在复发IE患者中占主导地位[33.1%比19.7%,p <；0.001]。热比;38°在IE复发病例中较少出现[34.8% vs. 54.1%, p <；0.001]。复发性IE患者以血培养阴性为主[43.3% vs. 27.2%, p <；0.001]。波兰复发性IE患者比欧洲同行很少接受手术治疗[55.2%比64.8%,p = 0.032]。栓塞手术指征在波兰不太突出[0.08%比20.2%,p <；0.001]。结论波兰的IE复发率较高。牙齿治疗和瓣膜修复易导致IE复发。热比;38°在复发性IE中较少观察到。波兰复发性IE患者未充分利用手术治疗。栓塞和无法控制的感染手术指征在波兰被低估。IE复发与住院死亡率增加无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IJC Heart and Vasculature Medicine-Cardiology and Cardiovascular Medicine

CiteScore

4.90

自引率

10.30%

发文量

216

审稿时长

56 days

期刊介绍： IJC Heart & Vasculature is an online-only, open-access journal dedicated to publishing original articles and reviews (also Editorials and Letters to the Editor) which report on structural and functional cardiovascular pathology, with an emphasis on imaging and disease pathophysiology. Articles must be authentic, educational, clinically relevant, and original in their content and scientific approach. IJC Heart & Vasculature requires the highest standards of scientific integrity in order to promote reliable, reproducible and verifiable research findings. All authors are advised to consult the Principles of Ethical Publishing in the International Journal of Cardiology before submitting a manuscript. Submission of a manuscript to this journal gives the publisher the right to publish that paper if it is accepted. Manuscripts may be edited to improve clarity and expression.