Interdisciplinary topics in gerontology and geriatrics最新文献_第3页

Are HIV-Infected Older Adults Aging Differently? 感染艾滋病毒的老年人衰老不同吗?

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448539

Stephen E Karpiak, Richard Havlik

{"title":"Are HIV-Infected Older Adults Aging Differently?","authors":"Stephen E Karpiak, Richard Havlik","doi":"10.1159/000448539","DOIUrl":"https://doi.org/10.1159/000448539","url":null,"abstract":"With increasing success in treating HIV, infected persons are living longer, and a new challenge has emerged - the need to understand how HIV-infected adults are aging. What are the similarities with typical aging and what are the unique aspects that may have resulted from HIV infection, interacting with characteristic life style factors and other comorbid conditions? Are specific diseases and conditions (comorbidities), typically seen as part of the aging process, occurring at accelerated rates or with higher frequency (accentuated) in HIV-infected adults? At this juncture, conclusions should be tentative. Certainly, biological processes that correlate with aging occur earlier in the older adult HIV population. Clinical manifestations of these biological processes are age-associated illnesses occurring in greater numbers (multimorbidity), but they are not accelerated. Specifically cardiovascular disease, certain cancers, and renal disease are more common with other comorbidities less certain. Management of this elevated risk for developing multimorbidity is a major concern for patients and their health care teams. The medical system must respond to the evolving needs of this aging and growing older adult population who will dominate the epidemic. Adopting a more holistic approach to their health care management is needed to achieve optimal health and well-being in the HIV-infected older adult. Geriatric care principles best embody this approach.","PeriodicalId":37866,"journal":{"name":"Interdisciplinary topics in gerontology and geriatrics","volume":"42 ","pages":"11-27"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000448539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39980905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Multimorbidity and Burden of Disease. 多病和疾病负担。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448544

Todd T Brown, Giovanni Guaraldi

引用次数: 17

Stigma in an Aging Context. 衰老背景下的病耻感。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448560

Charles A Emlet

引用次数: 10

Biomarkers and Clinical Indices of Aging with HIV. 衰老伴HIV的生物标志物及临床指标。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448543

Kathleen V Fitch, Meghan Noonan Feldpausch, Sara E Dolan Looby

引用次数: 7

Application of Geriatric Principles and Care Models in HIV and Aging. 老年学原理与护理模式在艾滋病与老龄化中的应用

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448549

Aroonsiri Sangarlangkarn, Anchalee Avihingsanon, Jonathan S Appelbaum

{"title":"Application of Geriatric Principles and Care Models in HIV and Aging.","authors":"Aroonsiri Sangarlangkarn, Anchalee Avihingsanon, Jonathan S Appelbaum","doi":"10.1159/000448549","DOIUrl":"https://doi.org/10.1159/000448549","url":null,"abstract":"People aging with HIV present a unique challenge for providers. HIV-infected patients experience accentuated aging and multimorbidity, but are typically disconnected from geriatric care, which is limited by a shortage of geriatric providers worldwide. Consequently, HIV providers are tasked with managing multiple age-related illnesses, within service networks that are historically not designed to care for aging patients. While comfortable with the management of antiretroviral therapy, HIV providers may have limited training on how to recognize or manage geriatric syndromes, especially in the context of multimorbidity. The result is an emerging, vulnerable population, and the question is how to best care for them. As part of the answer, we offer examples of how providers can use geriatric principles to improve the care of aging HIV-infected patients. We begin by describing basic geriatric concepts and examples of care models, and subsequently use a patient case to illustrate their applications at the patient level. At the system level, we discuss how HIV service networks can use components of geriatric care models to meet the needs of aging HIV-infected patients. Lastly, we identify aging-specific guidelines and service integration as important areas for future endeavors.","PeriodicalId":37866,"journal":{"name":"Interdisciplinary topics in gerontology and geriatrics","volume":"42 ","pages":"119-133"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000448549","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39980998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Local and Global HIV Aging Demographics and Research. 本地和全球艾滋病毒老龄化人口统计和研究。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448532

Courtenay Sprague, Shelley M Brown

引用次数: 9

Mental Health, Psychosocial Challenges and Resilience in Older Adults Living with HIV. 老年艾滋病毒感染者的心理健康、社会心理挑战和复原力。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448564

Perry N Halkitis, Kristen D Krause, Dorice L Vieira

{"title":"Mental Health, Psychosocial Challenges and Resilience in Older Adults Living with HIV.","authors":"Perry N Halkitis, Kristen D Krause, Dorice L Vieira","doi":"10.1159/000448564","DOIUrl":"https://doi.org/10.1159/000448564","url":null,"abstract":"In addition to physical health challenges, older people living with HIV/AIDS (PLWHA) experience mental health burdens and challenges to their social well-being that diminish their overall health. These health states are synergistic and are driven by HIV and HIV treatments, the aging process itself, and psychosocial and structural conditions of their lives. However, resilience, which we understand as both a trait and a process, may serve to buffer the effects that HIV/HIV treatments, aging, and social/structural conditions may have on the overall well-being of the individual. In this chapter, we examine the extant literate on the mental health and psychosocial challenges experienced by older PLWHA as elements of the total health of the individual. We also provide a contextualization and conceptualization for understanding the significant role that resilience may play in empowering individuals to enact processes which buffer health from the stressors. In this perspective, the health of older PLWHA must be viewed through a lens of power and strength rather than one of deficit. We conclude by outlining a theoretical paradigm for the role of resilience in the health of older HIV-positive adults, which may serve as a guide to clinicians, public health practitioners, and researchers working with this population.","PeriodicalId":37866,"journal":{"name":"Interdisciplinary topics in gerontology and geriatrics","volume":"42 ","pages":"187-203"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000448564","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39981478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 60

Polypharmacy, Using New Treatments to Customize Care for Aging Patients and Adherence Present and Future. 多药，使用新疗法定制老年患者护理和依从性现在和未来。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448545

Leonard H Alberts

引用次数: 2

Cellular Senescence, Immunosenescence and HIV. 细胞衰老、免疫衰老与HIV。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448542

Tamàs Fülöp, Georges Herbein, Andrea Cossarizza, Jacek M Witkowski, Eric Frost, Gilles Dupuis, Graham Pawelec, Anis Larbi

{"title":"Cellular Senescence, Immunosenescence and HIV.","authors":"Tamàs Fülöp, Georges Herbein, Andrea Cossarizza, Jacek M Witkowski, Eric Frost, Gilles Dupuis, Graham Pawelec, Anis Larbi","doi":"10.1159/000448542","DOIUrl":"https://doi.org/10.1159/000448542","url":null,"abstract":"Aging is a complex biological process that leads to several physiological changes. Among these changes, the most striking are those involving the innate and adaptive parts of the immune system. Furthermore, these changes are associated with a low-grade inflammation called inflamm-aging, which is the result of several lifelong antigenic stimulations, including chronic viral infections such as cytomegalovirus. Immunosenescence, concomitantly with inflamm-aging, is considered as the leading cause of age-related diseases including cardiovascular, neurodegenerative and metabolic diseases, and cancer. HIV infection, once considered a unique deadly infectious disease, has now become a chronic disease with efficacious highly active antiretroviral therapy. This signifies that the treatment transforms HIV infection from a chronic infection to a chronic inflammatory disease. Most people with HIV infection become aged, and older adults have been contracting HIV infection. Thus, there is a great interest to study HIV infection in relation to immunosenescence and inflamm-aging to determine whether immunosenescence contributes to HIV infection, or if HIV is causing immunosenescence and, as such, represents a premature immunosenescence and accelerated aging. Although there are many similarities in the immune and inflammatory changes and the occurrence of age-related chronic diseases between normal aging and HIV infection, the interaction between these processes is not well understood, and consequently the concept that HIV infection is an accelerated aging model is questioned. Future studies are needed to effectively answer this question for the better care of HIV-infected elderly patients.","PeriodicalId":37866,"journal":{"name":"Interdisciplinary topics in gerontology and geriatrics","volume":"42 ","pages":"28-46"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000448542","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39981059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Remediating HIV-Associated Neurocognitive Disorders via Cognitive Training: A Perspective on Neurocognitive Aging. 通过认知训练矫正 HIV 相关神经认知障碍：神经认知老化透视》。

Interdisciplinary topics in gerontology and geriatrics Pub Date : 2017-01-01 Epub Date: 2016-11-22 DOI: 10.1159/000448562

David E Vance, Shameka L Cody, Linda Moneyham

引用次数: 0