Infektsionnye Bolezni最新文献

{"title":"Risk factors for the spread of infectious diseases in the Arctics","authors":"L. Kraeva, A. Panin, A. E. Goncharov, D. Vlasov, N. Goncharov, V. B. Sboychakov","doi":"10.20953/1729-9225-2021-2-113-118","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-2-113-118","url":null,"abstract":"In the conditions of further development of the Arctic it is especially important to preserve the health of the population permanently or temporarily located in this territory. In recent years significant changes have taken place in the biosphere of the Arctic region under the influence of natural and anthropogenic factors. The population morbidity is accounted for by a number of diseases. However, the infectious component and the factors contributing to its growth remain poorly understood. Objective. To study various biocenoses in the Arctic region as potential risk areas for the spread of infectious diseases among the population. Materials and methods. The material for microbiological studies was selected in 2018–2019 in the archipelagos of Svalbard and Severnaya Zemlya. A total of 139 samples from various samples of natural, anthropogenic and ornithogenic biocenoses were studied. Research methods: classical bacteriological, MALDI-TOF mass spectrometric analysis, statistical data analysis. Results. During the study of Arctic samples were isolated and identified 309 viable bacterial strains and representatives of 117 species of micromycetes. Of all the isolated strains, the most important are Escherichia coli, Yersinia intermedia, representatives of the genera Acinetobacter, Pseudomonas, Stenotrophomonas, Serratia, Enterobacter, Enterococcus, and Staphylococcus. Conclusion. The risk factors for the spread of infectious disease pathogens in the Arctic region were identified: an increase in the number and diversity of isolated microorganisms of medical significance in dynamics; identification of pathogens of infections associated with medical care and saprozoonoses among them. Key words: Arctic, Svalbard and Severnaya Zemlya archipelagos, infectious diseases, pathogens of medical care-related infections and saprozoonoses, polar microorganisms","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67724931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulation of influenza viruses in the epidemic season of 2018–2019 among people residing in Northern and Western Kazakhstan","authors":"T. Glebova, Almaty Kazakhstan Virology», N. Klivleyeva, A. Baimukhametova, N. Saktaganov, G. Lukmanova, N. Ongarbayeva, M. Shamenova, B. Baimakhanova","doi":"10.20953/1729-9225-2021-2-70-75","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-2-70-75","url":null,"abstract":"Objective. Detection of influenza viruses among the population on the territory of the Northern and Western Kazakhstan during the 2018–2019 epidemic season. Patients and methods. The study involved 835 patients with ARVI symptoms. Biological samples were screened in real-time polymerase chain reaction (RT-PCR), hemagglutination inhibition (HAI) assay, and enzyme-linked immunosorbent assay (ELISA). Hemagglutinating agents were isolated in 9-10-day-old developing chicken embryos. Identification of isolates was carried out in RT-PCR and HAI assay. Results. 936 clinical samples (835 nasopharyngeal swabs and 101 blood serums) were collected from patients in the Northern (North Kazakhstan and Pavlodar oblasts) and Western (West Kazakhstan oblast) regions during the 2018–2019 epidemic season. Primary screening of 835 nasopharyngeal swabs revealed the genetic material of influenza virus in 20.48%, influenza A virus in 20.36%, and influenza B virus in 0.12%. Subtyping of PCR positive samples for influenza type A virus showed the presence of the genetic material of influenza A/H1N1pdm09 virus in 14.01%, A/H3N2 virus in 4.91%. The virus subtype was not established in 1.66%. Virological examination of nasopharyngeal swabs led to obtaining 14 isolates, of which 13 were identified as influenza A/H1N1pdm09 viruses and 1 as influenza A/H3N2 virus. Serological studies of 101 blood serums in the HAI assay showed the presence of antihemagglutinins against influenza A/H1N1pdm09 virus in 28.71%, A/H3N2 virus in 30.69%, type B virus in 3.96% of the total number of samples. Antibodies simultaneously against two subtypes of influenza viruses (A and B) were detected in 12.87% of cases. In ELISA antibodies against influenza A/H1N1 virus were revealed in 24.75% of cases, A/H3N2 virus in 19.80%, type B virus in 14.85%. Antibodies simultaneously against two types of influenza viruses (A and B) were detected in 2.97% of blood serums. Conclusion. The results of virological and serological studies presented in the paper suggest circulation of influenza A/H1N1pdm09, A/H3N2, and type B viruses in the examined oblasts of Kazakhstan during the 2018–2019 season. Key words: virus, hemagglutinin, influenza, diagnosis, isolate, neuraminidase, circulation","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67725295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and epidemiological significance of diarrhea in children with COVID-19","authors":"L. N. Mazankovа, S. G. Gorbunov, E. Samitova, I. Osmanov, V. Akimkin, A. Ploskireva, А.N. Os’kin, A. Mishkin","doi":"10.20953/1729-9225-2021-3-30-36","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-3-30-36","url":null,"abstract":"Objective. To show the clinical and epidemiological significance of diarrhea and SARS-CoV-2 excretion in the feces of COVID-19 patients in children. Patients and methods. 42 case histories of children with COVID-19 hospitalized and examined by PCR for SARS-CoV-2 RNA in nasal and oropharyngeal swabs, as well as in feces were ana-lyzed. Design: retrospective analysis of patient medical records. Results. It was shown that watery diarrhea was observed in 2.4% of children with verified COVID-19, vomiting and abdominal pain – in 4.8%. In the blood test, lymphocytosis prevailed. In all the examined patients, SARS-CoV-2 RNA was detected not only in nasal and oropharyngeal swabs, but also in feces, while in 4.8% of children, the virus was excreted in feces for a longer time than in the respiratory tract. In the epidemiological history of 100% of patients, there was no indication of contact with a patient with acute diarrhea. Conclusion. These facts indicate that, despite the infrequently registered diarrhea in COVID-19 in childhood, the detection of SARS-CoV-2 RNA in the feces of a significant number of such patients may have important clinical and epidemiological significance, contributing to the fecaloral transmission of this infection, which requires additional study due to the small number and incon-sistency of currently known data. Key words: diarrhea, COVID-19, SARS-CoV-2, children","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67726156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Favorable outcome of progressive multifocal leukoencephalopathy in an HIV-infected patient","authors":"E. A. Samotolkina, A. Pokrovskaya, E. S. Samotolkina, D. Popova, Moscow Russian Federation Human Wellbeing","doi":"10.20953/1729-9225-2021-1-131-134","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-1-131-134","url":null,"abstract":"In this article, we report a case of progressive multifocal leukoencephalopathy in an HIV-infected patient receiving antiretroviral therapy. The case is interesting because of its favorable outcome despite severe clinical manifestations of the disease. Key words: HIV infection, case report, progressive multifocal leukoencephalopathy","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67724028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemic process of COVID-19 in the Russian Federation: interim results. 2nd report","authors":"N. Pshenichnaya, G. Zhuravlev, A. A. Erovichenkov, V. Akimkin","doi":"10.20953/1729-9225-2021-1-10-15","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-1-10-15","url":null,"abstract":"Objective. To perform an interim analysis of epidemiological parameters of COVID-19 related to contacts and secondary cases of infection in the Russian Federation. Materials and methods. We analyzed 190,856 primary COVID-19 cases and 146,996 people who had been in contact with them. We used some data of monitoring performed by the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing in January–June 2020. We characterized the foci of infection and people who had contacts with primary COVID-19 cases and secondary cases of infection. Results. Just over half (50.02%) of study participants who had contacts with COVID-19 contacted with primary patients with mild disease, whereas 45.40% of individuals contacted with patients with moderate disease and 4.58% of individuals had contacts with patients with severe disease. Patients with mild COVID-19 interacted with more people, which resulted in a greater number of secondary cases of infection. The highest proportion of both primary COVID-19 patients and people who had contact with COVID-19 was observed in the age group of 41–64 years (44.42% and 44.51%, respectively). Approximately one third of COVID-19 patients and people who had contact with COVID-19 were 18 to 40 years old (30.20% and 34.21% respectively). The proportions of children aged 0–6 years and 7–17 years among COVID-19 patients were 2.70% and 4.02%, respectively; the same proportions among those who had contact with COVID-19 cases were 1.94 and 3.13%, respectively. Household contacts were the most common ways of COVID-19 transmission in all age groups. Patients aged between 40 and 64 years played the most significant role in the transmission of this infection in different foci. Individuals from this age group comprised 42.02% of patients infected in social institutions, 43.40% of those who had household contacts, and 47.70% of those infected at work. Conclusion. Patients with mild and moderate disease aged 18 to 64 years had the highest number of contacts and, therefore, caused the highest number of secondary cases of infection. Household contacts played the most important role in COVID-19 transmission in all age groups. Among people aged 18 to 64 years, COVID-19 transmission at work was also important. In all foci of infection, the majority of patients were in the age group of 40–64 years. Our findings can be used to optimize the preventive measures for COVID-19. Key words: epidemic process, age groups, severity, contacts, COVID-19, Russia, household contacts","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"313 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67724109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of single-nucleotide polymorphisms associated with an increased risk of immune reconstitution inflammatory syndrome in patients with tuberculosis and HIV","authors":"A. Bukharina, Moscow Russian Federation Human Wellbeing, K. Mironov, V. Zimina","doi":"10.20953/1729-9225-2021-1-97-104","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-1-97-104","url":null,"abstract":"Tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) is the development or progression of tuberculosis associated with restoration of active immune response to mycobacteria following the initiation of antiretroviral therapy in HIVinfected patients. The incidence of TB-IRIS is 18% with mortality reaching 2%. Investigation of TB-IRIS in Russia is very important, since the prevalence of TB coinfection is common among HIV-infected patients; in addition to that, HIV is often detected at late stages characterized by severe immunosuppression, which increases the risk of TB-IRIS. This review focuses on single-nucleotide polymorphisms and some other genetic factors associated with an increased risk of TB-IRIS. Key words: antiretroviral therapy, HIV infection, genetic predisposition, single-nucleotide polymorphisms, TB-IRIS, tuberculosis, gene expression","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67724724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and laboratory characteristics of patients with chronic hepatitis C and severe interferon system suppression","authors":"Z. Ponezheva, I. Mannanova, V. Makashova, A. A. Erovichenkov, S. Shabalina, A. Gorelov","doi":"10.20953/1729-9225-2021-2-60-64","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-2-60-64","url":null,"abstract":"Objective. To identify specific clinical and laboratory characteristics of patients with chronic hepatitis C (CHC) and severe interferon (IFN) system suppression. Patients and methods. This study was conducted at the Clinical Department of Infectious Pathology, Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. We enrolled and examined 76 patients with confirmed CHC aged 18 to 80 years who had been followed up for at least 3 years. We analyzed the level of IFN-producing T-lymphocytes, IFN status, serum levels of IFN-α, -γ and -λ depending on viral and biochemical activity, and genotype. In addition to that, we evaluated the association between the IFN system parameters and age, duration of infection, genotype, viral load, and stage of liver fibrosis. The control group comprised 30 healthy individuals who had no complaints and no clinical or laboratory changes at the time of examination. Results. We identified 3 grades of IFN system suppression: grade 1–moderate (in 21% of patients), grade 2–mild (inadequate) (in 47% of patients), and grade 3–severe (in 32% of patients). We analyzed clinical and laboratory characteristics of patients with grade 3 IFN system suppression and evaluated the IFN system depending on age, duration of infection, genotype, viral and biochemical activity. We found that severe IFN system suppression correlated with duration of infection, stage of liver fibrosis with a tendency to increased levels of T-lymphocytes expressing receptors for IFN-α and IFN-γ (CD118+, CD119+). Key words: chronic hepatitis C, genotype, interferon status","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67725614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serotonin adipate in intensive therapy of patients with severe COVID-19","authors":"M. V. Bykov, D.V. Chernyshyov, E. Lazareva, S. V. Krasnova, N. A. Tsvetkova, Z. Ponezheva, V. Akimkin, V. Maleev","doi":"10.20953/1729-9225-2021-3-139-145","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-3-139-145","url":null,"abstract":"In this article, we discuss the history of discovery of serotonin deficiency and therapy for it. We described the experience of using serotonin adipate as a part of comprehensive intensive therapy for severe COVID-19. We also describe treatment outcome of a 52-year-old female patient treated in the intensive care unit of the Clinical Hospital for Infectious Diseases No 2 with a diagnosis of community-acquired polysegmental pneumonia, confirmed COVID-19, and functional intestinal obstruction. Her condition was complicated by infectious and toxic dilated cardiomyopathy of mixed origin (caused by both coronavirus itself and substrates of enterogenic endotoxicosis) and hemodynamic instability manifesting itself with arterial hypotension that required micro-injections of norepinephrine. The comprehensive treatment aimed to eliminate growing endotoxicosis caused by intestinal insufficiency, so we had to adjust her intensive therapy by adding serotonin adipate to the treatment scheme. Good treatment outcome of this patient was ensured by an improved strategy of intensive therapy that included a drug restoring and stimulating functions of smooth muscles. Later, the patient was transferred to the specialized department, recovered, and discharged from hospital. Key words: intensive care, COVID-19, serotonin adipate","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67725915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucellosis in Omsk region in 2008–2018","authors":"A. Nurpeysova, Yu. A. Pnevskiy, A. Ivanchikov, V.Yu. Pleshkov, D.I. Aleksandrova, E. Lyapina","doi":"10.20953/1729-9225-2021-2-95-100","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-2-95-100","url":null,"abstract":"Omsk region is part of the Siberian Federal district (SFD), for many years the situation on brucellosis in the region is characterized as unstable. The objective of the study was to analyze the clinical and epidemiological situation of brucellosis in Omsk and Omsk region in 2008–2018 and to identify the relationship between the incidence of brucellosis in humans and the location of enterprises for processing animal products. Material and methods. We have conducted an analysis of 407 of official records in epidemiologi-epidemiological situation in the Omsk region for the period 2008–2018 and the data portal, participants of the market of dairy (http://milknet.ru) and cold (http://meatinfo.ru) products. Results. Indicators of the incidence of brucellosis in the region exceeded significantly those in the Siberian Federal district and Russia in general. The peak of brucellosis incidence in Omsk region was in 2008–2010. The risk groups were people of working age (40–59 years). The connection of the disease with the profession was established in 44 patients with brucellosis. The prevalence of chronic brucellosis in 41 (45.0%) patients and residual brucellosis in 12 (13.0%) patients over other clinical variants was revealed. Epizootological situation of brucellosis in Omsk region was characterized as unstable. During the analyzed period, 22 unfavorable points on brucellosis of farm animals were registered. Most of the problem areas (20 out of 22) were identified in private households. The number of cases of brucellosis is comparable with the number of enterprises for processing raw materials of animal origin. Conclusion. To improve the effectiveness of measures taken to combat brucellosis in the region, strict monitoring of compliance with sanitary and anti-epidemic measures in enterprises of all forms of ownership and real programs to support private owners of the animals. Key words: brucellosis, Omsk region, epidemic situation, epizootic situation","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67725439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and mechanisms underlying the development of organ pathology in patients with chronic brucellosis","authors":"E. Lyapina, A. Shuldyakov, A. V. Sofina, G. Kozhevnikova, A. Nurpeisova, A. Danilov, A. V. Anashchenko, A. Evdokimov, E. Zubareva, Y. Linkova, A. N. Smagina, E.G. Gladilina","doi":"10.20953/1729-9225-2021-3-67-77","DOIUrl":"https://doi.org/10.20953/1729-9225-2021-3-67-77","url":null,"abstract":"Objective. To analyze specific characteristics and mechanisms underlying the development of organ pathology in patients with chronic brucellosis (CB). Patients and methods. This study included more than 500 patients with CB treated in Saratov hospitals in 2003–2018. In addition to standard examination, all study participants have undergone the assessment of their lipid peroxidation/antioxidant defense system, levels of major cytokines, markers of endotoxicosis (ET), and tissue-specific autoreactive antibodies. Results and discussion. The vast majority of patients (98.2%) had their musculoskeletal system affected; lesions to the autonomic nervous system and peripheral nervous system were observed in 97.5% and 88.8% of patients, respectively; almost half of males (45%) had their reproductive organs affected; approximately one-third of participants (26.7–32.9%) had cardiovascular disorders with myocardial lesions. The severity of systemic inflammation, ET, and autoimmune reactions depended on the CB activity and determined the development of organ pathology. We found that vascular and mechanical factors were important for the development of lesions to the peripheral nervous system and reproductive organs in men. Patients, in whom the diagnosis of CB was verified 2 years following onset of symptoms, were more likely to develop exacerbations, had more organs and systems affected, and had higher risk of disability. Conclusion. Comprehensive examination revealed multiple organ lesions in all CB patients, associated not only with damage caused by the pathogen at the site of specific inflammation, but also with the involvement of vascular and mechanical factors, as well as the consequences of systemic inflammatory response, ET, and autoimmune reactions. Late diagnosis was associated with more severe clinical manifestations of CB. Key words: brucellosis, clinical manifestations of chronic brucellosis, systemic inflammation, endotoxicosis","PeriodicalId":37794,"journal":{"name":"Infektsionnye Bolezni","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67725847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}