Retina (Philadelphia, Pa.)最新文献

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SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES. 血管增殖性视网膜肿瘤对非侵入性治疗的手术效果。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-09-01 DOI: 10.1097/IAE.0000000000003520
Virginia Mares, Carlos E Veloso, Jose S Pulido, Marcio B Nehemy
{"title":"SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES.","authors":"Virginia Mares,&nbsp;Carlos E Veloso,&nbsp;Jose S Pulido,&nbsp;Marcio B Nehemy","doi":"10.1097/IAE.0000000000003520","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003520","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the outcomes of surgical treatment of refractory vasoproliferative retinal tumors (VPTs) and its complications.</p><p><strong>Methods: </strong>Clinical charts of all patients diagnosed with VPTs who underwent surgical treatment from 2005 to 2020 were reviewed. Clinical features, surgical techniques, and outcomes were evaluated.</p><p><strong>Results: </strong>From 25 eyes of 23 patients with VPTs, 17 (68%) eyes underwent surgical intervention to treat tumor activity and associated complications including epiretinal membrane (n = 10, 59%), retinal detachment (n = 8, 47%), and vitreous hemorrhage (n = 3, 18%). All eyes underwent pars plana vitrectomy with endolaser/cryotherapy to control tumor activity and to treat associated complications. Three cases required tumor resection. At the end of follow-up (mean 55.4 months, range 2-305 months), no eye presented tumor activity or retinal detachment after one or two surgeries. There was no epiretinal membrane recurrence. The mean baseline best-corrected visual acuity was 1.2 ± 0.7 logMAR, and the mean final best-corrected visual acuity was 0.7 ± 0.6 logMAR ( P < 0.05). The best-corrected visual acuity improved two or more lines in 12 (70.5%) eyes at the end of follow-up.</p><p><strong>Conclusion: </strong>In this series of patients with large active VPTs, surgical intervention allowed control of the tumor activity in all patients and provided overall satisfactory anatomic and functional outcomes.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1772-1779"},"PeriodicalIF":3.3,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40434776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PERIPHERAL CHOROIDAL THICKNESS DETERMINED BY WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY IN EYES WITH CENTRAL SEROUS CHORIORETINOPATHY. 中枢性浆液性脉络膜视网膜病变眼的宽视场光学相干断层扫描测定周围脉络膜厚度。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003478
Soichiro Nishihara, Ichiro Maruko, Takahiko Izumi, Taizo Kawano, Tomohiro Iida
{"title":"PERIPHERAL CHOROIDAL THICKNESS DETERMINED BY WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY IN EYES WITH CENTRAL SEROUS CHORIORETINOPATHY.","authors":"Soichiro Nishihara,&nbsp;Ichiro Maruko,&nbsp;Takahiko Izumi,&nbsp;Taizo Kawano,&nbsp;Tomohiro Iida","doi":"10.1097/IAE.0000000000003478","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003478","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the central and peripheral choroidal thickness in eyes with central serous chorioretinopathy (CSC) and to compare these thicknesses values with those of control normal eyes.</p><p><strong>Methods: </strong>Wide-field optical coherence tomographic images of 24 eyes of 19 patients with CSC and 14 normal eyes of 7 individuals were recorded. A 20-mm vertical scan through the fovea was obtained with the Xephilio optical coherence tomographic S1 (Canon, Japan), a wide-field optical coherence tomographic device. The subfoveal choroidal thickness and the thickness at 5 mm superior (S5) and inferior (I5), 7 mm superior (S7) and inferior (I7), 8.5 mm superior (S8) and inferior (I8), and 10 mm superior (S10) and inferior (I10) from the fovea in the CSC eyes and normal eyes were compared.</p><p><strong>Results: </strong>There was no significant difference in the age ( P = 0.8) or the refractive error ( P = 0.7) between the CSC and normal eyes. The choroidal thickness was significantly thicker in the eyes with CSC than that in the normal eyes at subfoveal choroidal thickness ( P < 0.01), S5 ( P = 0.01), and S7 ( P = 0.02). However, there was no significant difference in the choroidal thickness at the more peripheral points (all P > 0.1).</p><p><strong>Conclusion: </strong>The thickened choroid in CSC was observed at the fovea and the area just superior to the fovea. The pathogenesis of CSC may be associated with the choroidal thickening confined to the fovea and superior foveal area.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1450-1454"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40328096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
COMPARISON OF SURGEON MUSCULAR PROPERTIES BETWEEN STANDARD OPERATING MICROSCOPE AND DIGITALLY ASSISTED VITREORETINAL SURGERY SYSTEMS. 标准手术显微镜与数字辅助玻璃体视网膜手术系统外科医生肌肉特性的比较。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003482
Su Jin Park, Jong-Moon Hwang, Eugene Jae Jin Park, Jae Pil Shin, Dong Ho Park
{"title":"COMPARISON OF SURGEON MUSCULAR PROPERTIES BETWEEN STANDARD OPERATING MICROSCOPE AND DIGITALLY ASSISTED VITREORETINAL SURGERY SYSTEMS.","authors":"Su Jin Park,&nbsp;Jong-Moon Hwang,&nbsp;Eugene Jae Jin Park,&nbsp;Jae Pil Shin,&nbsp;Dong Ho Park","doi":"10.1097/IAE.0000000000003482","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003482","url":null,"abstract":"<p><strong>Purpose: </strong>To quantitatively analyze surgical ergonomics between standard operating microscope (SOM) and digitally assisted vitreoretinal surgery (DAVS) systems.</p><p><strong>Methods: </strong>The surgeon conducted procedures on 110 patients; 52 patients underwent a combined phacoemulsification and pars plana vitrectomy (Phaco-PPV group, 24 using SOM and 28 using DAVS), and 58 patients underwent phacoemulsification (Phaco group, 30 using SOM and 28 using DAVS). The surgeon's muscle tone and stiffness in the sternocleidomastoid and the two positions of the upper trapezius (UT), which are 2-cm intervals along the UT muscle fibers, UT1 and UT2, were measured at preoperative, intraoperative, and postoperative time points.</p><p><strong>Results: </strong>In the Phaco-PPV group using the SOM, intraoperative muscle tone and stiffness were higher than preoperative and postoperative values in the sternocleidomastoid ( P < 0.001, respectively), UT1 ( P < 0.001, respectively), and UT2 ( P < 0.001 and P < 0.01, respectively). In the Phaco group using the SOM, intraoperative muscle tone and stiffness were higher than pre- and postoperative values in the sternocleidomastoid ( P < 0.001, respectively) and UT1 ( P < 0.001 and P < 0.01, respectively). By contrast, when the surgeon used the DAVS, there were no differences in muscle properties at any measurement site or during any time point in the Phaco-PPV and Phaco groups ( P > 0.05).</p><p><strong>Conclusion: </strong>This study provides quantitative measurement of retina surgeon ergonomics, suggesting that compared with a SOM, the DAVS can reduce intraoperative muscle fatigue.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1583-1591"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40328097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Shifting Lens Forward by Suture Drainage of Anterior Chamber Prevents Lens Damage During Peripheral Vitrectomy. 外周玻璃体切除术中前房缝线引流前移晶状体可防止晶状体损伤。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000002513
Dongqing Zhu, Yan Liu, Rong Huang, Jing Zhang, Jibo Zhou
{"title":"Shifting Lens Forward by Suture Drainage of Anterior Chamber Prevents Lens Damage During Peripheral Vitrectomy.","authors":"Dongqing Zhu,&nbsp;Yan Liu,&nbsp;Rong Huang,&nbsp;Jing Zhang,&nbsp;Jibo Zhou","doi":"10.1097/IAE.0000000000002513","DOIUrl":"https://doi.org/10.1097/IAE.0000000000002513","url":null,"abstract":"Supplemental Digital Content is Available in the Text.","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1608-1611"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/IAE.0000000000002513","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40537330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IDIOPATHIC MULTIFOCAL CHOROIDITIS WITH SERPIGINOUS-LIKE PERIPAPILLARY CHORIORETINAL ATROPHY. 特发性多灶性脉络膜炎伴蛇形样乳头周围脉络膜视网膜萎缩。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003481
Kareem Moussa, Joseph B Alsberge, Marion R Munk, Robin A Vora, Parisa Emami-Naeini, Glenn Yiu, Emmett T Cunningham
{"title":"IDIOPATHIC MULTIFOCAL CHOROIDITIS WITH SERPIGINOUS-LIKE PERIPAPILLARY CHORIORETINAL ATROPHY.","authors":"Kareem Moussa,&nbsp;Joseph B Alsberge,&nbsp;Marion R Munk,&nbsp;Robin A Vora,&nbsp;Parisa Emami-Naeini,&nbsp;Glenn Yiu,&nbsp;Emmett T Cunningham","doi":"10.1097/IAE.0000000000003481","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003481","url":null,"abstract":"<p><strong>Purpose: </strong>To report nine cases of multifocal choroiditis with serpiginous-like peripapillary chorioretinal atrophy.</p><p><strong>Methods: </strong>A retrospective observational case series of eyes with multifocal choroiditis with serpiginous-like peripapillary chorioretinal atrophy. Multimodal imaging findings were reviewed and presented.</p><p><strong>Results: </strong>Fifteen eyes of 9 patients (6 women and 3 men), with a mean age of 48.1 years (median, 46 years; range, 23-74 years), presented with multifocal choroiditis serpiginous-like peripapillary chorioretinal atrophy. All 15 eyes presented with serpiginoid peripapillary changes and had discrete patches of atrophy or punched-out scars in the posterior pole or periphery. Eleven eyes (73.3%) had cone-shaped retinal pigment epithelium elevations on optical coherence tomography, 10 eyes (66.7%) had mild vitritis, and 4 eyes (26.7%) had peripheral curvilinear streak lesions. Three eyes (20%) had choroidal neovascularization. All patients responded well to treatment with systemic immunosuppression, local corticosteroid injections, and/or intravitreal anti-vascular endothelial growth factor injections.</p><p><strong>Conclusion: </strong>Multifocal choroiditis may present with peripapillary chorioretinal changes resembling a serpiginous-like choroiditis in addition to the classic findings of patches of atrophy or punched-out scars in the posterior pole or periphery, cone-shaped retinal pigment epithelium elevated on optical coherence tomography and peripheral curvilinear streak lesions.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1574-1582"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40328093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
IMAGING THE VITREOUS WITH A NOVEL BOOSTED OPTICAL COHERENCE TOMOGRAPHY TECHNIQUE: Vitreous Degeneration and Cisterns. 用一种新的增强光学相干断层成像技术对玻璃体进行成像:玻璃体变性和玻璃体池。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003474
Richard F Spaide, Philippe Valmaggia, Peter M Maloca, Hendrik P N Scholl, Tilman P Otto, Sophie Caujolle
{"title":"IMAGING THE VITREOUS WITH A NOVEL BOOSTED OPTICAL COHERENCE TOMOGRAPHY TECHNIQUE: Vitreous Degeneration and Cisterns.","authors":"Richard F Spaide,&nbsp;Philippe Valmaggia,&nbsp;Peter M Maloca,&nbsp;Hendrik P N Scholl,&nbsp;Tilman P Otto,&nbsp;Sophie Caujolle","doi":"10.1097/IAE.0000000000003474","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003474","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the degenerative findings including cistern formation in the premacular vitreous using optical coherence tomography.</p><p><strong>Methods: </strong>A novel enhanced vitreous imaging method by which four A-scans at each position were averaged before the Fourier transform increased the image quality per frame so that subsequent image registration for averaging could occur. Analysis of B-scans and volume-rendered images of eyes in subjects of various ages was performed.</p><p><strong>Results: </strong>There were 43 eyes of 23 subjects ranging in age from 23 to 68 years. The texture in the vitreous images suggests specific orientations of the vitreous fibers in the macular region; there were fibers circumferential to the retina immediately anterior to the premacular bursa. The pattern of the vitreous fibers seemed less well-defined internal to the zone of circumferential fibers. In younger eyes, there were striations oriented in a roughly inferior to superior direction in this zone. In older eyes, there were striations in the same orientation but actually were alternating zones of vitreous synchysis and syneresis. In these same eyes, numerous cisterns appeared at various levels in the vitreous gel. With extensive vitreous condensation and synchysis, definition of the premacular bursa was lost.</p><p><strong>Conclusion: </strong>With this novel method of enhanced vitreous imaging, the vitreous seemed to have stereotypic patterns of degeneration. The formation of vitreous syneresis and synchysis may be related to organization architecture of the vitreous, including the pattern of vitreous collagen deposition, and the effects of eye motion through decades of time.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1433-1441"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40328098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
INTRAVITREAL ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO OCULAR HISTOPLASMOSIS: Ten-Year Follow-Up. 玻璃体内抗血管内皮生长因子治疗眼组织浆菌病继发脉络膜新生血管:10年随访。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003488
Nicholas E Dudenhoefer, Carl W Noble, Michael R Petersen, Robert E Foster, Christopher D Riemann, Robert A Sisk, Robert K Hutchins, Daniel M Miller
{"title":"INTRAVITREAL ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO OCULAR HISTOPLASMOSIS: Ten-Year Follow-Up.","authors":"Nicholas E Dudenhoefer,&nbsp;Carl W Noble,&nbsp;Michael R Petersen,&nbsp;Robert E Foster,&nbsp;Christopher D Riemann,&nbsp;Robert A Sisk,&nbsp;Robert K Hutchins,&nbsp;Daniel M Miller","doi":"10.1097/IAE.0000000000003488","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003488","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the long-term efficacy of intravitreal antivascular endothelial growth factor injections (IVI), alone or in combination with verteporfin photodynamic therapy (IVI/PDT), for management of choroidal neovascularization secondary to presumed ocular histoplasmosis syndrome (POHS).</p><p><strong>Methods: </strong>Retrospective, comparative, interventional case series analyzing 82 eyes in 74 patients treated with either IVI or IVI/PDT for presumed ocular histoplasmosis syndrome choroidal neovascularization from January 2006 to January 2021.</p><p><strong>Results: </strong>The average logarithm of the minimum angle of resolution VA in year 5 was 0.40 (20/50) and 0.52 (20/67) for IVI versus IVI/PDT groups, respectively ( P = 0.33), and in year 10 was 0.53 (20/58) and 0.64 (20/86), respectively ( P = 0.50). The average number of annual injections over the first 5 years of follow-up was 3.3 versus 1.7 for IVI versus IVI/PDT groups, respectively ( P < 0.001), and over 10 years was 3.3 versus 1.6, respectively ( P < 0.001). Treatment-free interval of 5 years was reached by 39% versus 60% in IVI versus IVI/PDT groups, respectively ( P = 0.95).</p><p><strong>Conclusion: </strong>Our study found both IVI and IVI/PDT to be effective in long-term management of presumed ocular histoplasmosis syndrome choroidal neovascularization, with a fewer number of annual injections and longer treatment-free interval in the combination group. However, given the limitations of a retrospective study, a prospective randomized study is necessary to determine whether the addition of PDT significantly decreases treatment burden.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1568-1573"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40647357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OCULAR FACTORS RELATED TO PREOPERATIVE ENLARGEMENT OF IDIOPATHIC MACULAR HOLE DIAMETER. 与术前特发性黄斑孔直径增大有关的眼部因素。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003490
Hiroto Terasaki, Toshifumi Yamashita, Ryoh Funatsu, Hideki Shiihara, Takehiro Yamashita, Taiji Sakamoto
{"title":"OCULAR FACTORS RELATED TO PREOPERATIVE ENLARGEMENT OF IDIOPATHIC MACULAR HOLE DIAMETER.","authors":"Hiroto Terasaki,&nbsp;Toshifumi Yamashita,&nbsp;Ryoh Funatsu,&nbsp;Hideki Shiihara,&nbsp;Takehiro Yamashita,&nbsp;Taiji Sakamoto","doi":"10.1097/IAE.0000000000003490","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003490","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the preoperative factors that are significantly correlated with an enlargement of an idiopathic macular hole (MH) during the one-month preoperative period.</p><p><strong>Methods: </strong>This was a retrospective cross-sectional study of patients with MH who had undergone vitrectomy in the Kagoshima University Hospital. The stage of the MH was determined by using spectral domain optical coherence tomography. Patients who had optical coherence tomography images at two time points more than 14 days apart before the vitrectomy were studied.</p><p><strong>Results: </strong>The MH participants were at Stage 2 in 44 eyes, at Stage 3 in 58 eyes, and at Stage 4 in 38 eyes. The rate of increase of the hole diameter was 26.0 ± 42.3% at Stage 2, 5.52 ± 15.5% at Stage 3, and 8.04 ± 18.7% at Stage 4. The rate of change at Stage 2 was significantly greater than that at Stage 3 and Stage 4 (both P < 0.01). In Stage 2, the MH diameter at the initial visit was significantly and negatively correlated with the rate of MH enlargement (r = -0.35, P = 0.021).</p><p><strong>Conclusion: </strong>Patients with Stage 2 MHs, especially eyes with small hole diameter, should be considered for early surgery.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1484-1490"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40647355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A SYSTEMATIC REVIEW OF DEEP LEARNING APPLICATIONS FOR OPTICAL COHERENCE TOMOGRAPHY IN AGE-RELATED MACULAR DEGENERATION. 深度学习在光学相干断层扫描中应用于老年性黄斑变性的系统综述。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003535
Samantha K Paul, Ian Pan, Warren M Sobol
{"title":"A SYSTEMATIC REVIEW OF DEEP LEARNING APPLICATIONS FOR OPTICAL COHERENCE TOMOGRAPHY IN AGE-RELATED MACULAR DEGENERATION.","authors":"Samantha K Paul,&nbsp;Ian Pan,&nbsp;Warren M Sobol","doi":"10.1097/IAE.0000000000003535","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003535","url":null,"abstract":"<p><strong>Purpose: </strong>To survey the current literature regarding applications of deep learning to optical coherence tomography in age-related macular degeneration (AMD).</p><p><strong>Methods: </strong>A Preferred Reporting Items for Systematic Reviews and Meta-Analyses systematic review was conducted from January 1, 2000, to May 9, 2021, using PubMed and EMBASE databases. Original research investigations that applied deep learning to optical coherence tomography in patients with AMD or features of AMD (choroidal neovascularization, geographic atrophy, and drusen) were included. Summary statements, data set characteristics, and performance metrics were extracted from included articles for analysis.</p><p><strong>Results: </strong>We identified 95 articles for this review. The majority of articles fell into one of six categories: 1) classification of AMD or AMD biomarkers (n = 40); 2) segmentation of AMD biomarkers (n = 20); 3) segmentation of retinal layers or the choroid in patients with AMD (n = 7); 4) assessing treatment response and disease progression (n = 13); 5) predicting visual function (n = 6); and 6) determining the need for referral to a retina specialist (n = 3).</p><p><strong>Conclusion: </strong>Deep learning models generally achieved high performance, at times comparable with that of specialists. However, external validation and experimental parameters enabling reproducibility were often limited. Prospective studies that demonstrate generalizability and clinical utility of these models are needed.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1417-1424"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40624465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
DEEP LEARNING-BASED PREDICTION OF OUTCOMES FOLLOWING NONCOMPLICATED EPIRETINAL MEMBRANE SURGERY. 基于深度学习的非复杂视网膜前膜手术预后预测。
IF 3.3
Retina (Philadelphia, Pa.) Pub Date : 2022-08-01 DOI: 10.1097/IAE.0000000000003480
Soo Han Kim, Honggi Ahn, Sejung Yang, Sung Soo Kim, Jong Hyuck Lee
{"title":"DEEP LEARNING-BASED PREDICTION OF OUTCOMES FOLLOWING NONCOMPLICATED EPIRETINAL MEMBRANE SURGERY.","authors":"Soo Han Kim,&nbsp;Honggi Ahn,&nbsp;Sejung Yang,&nbsp;Sung Soo Kim,&nbsp;Jong Hyuck Lee","doi":"10.1097/IAE.0000000000003480","DOIUrl":"https://doi.org/10.1097/IAE.0000000000003480","url":null,"abstract":"<p><strong>Purpose: </strong>We used deep learning to predict the final central foveal thickness (CFT), changes in CFT, final best corrected visual acuity, and best corrected visual acuity changes following noncomplicated idiopathic epiretinal membrane surgery.</p><p><strong>Methods: </strong>Data of patients who underwent noncomplicated epiretinal membrane surgery at Severance Hospital from January 1, 2010, to December 31, 2018, were reviewed. Patient age, sex, hypertension and diabetes statuses, and preoperative optical coherence tomography scans were noted. For image analysis and model development, a pre-trained VGG16 was adopted. The mean absolute error and coefficient of determination (R 2 ) were used to evaluate the model performances. The study involved 688 eyes of 657 patients.</p><p><strong>Results: </strong>For final CFT, the mean absolute error was the lowest in the model that considered only clinical and demographic characteristics; the highest accuracy was achieved by the model that considered all clinical and surgical information. For CFT changes, models utilizing clinical and surgical information showed the best performance. However, our best model failed to predict the final best corrected visual acuity and best corrected visual acuity changes.</p><p><strong>Conclusion: </strong>A deep learning model predicted the final CFT and CFT changes in patients 1 year after epiretinal membrane surgery. Central foveal thickness prediction showed the best results when demographic factors, comorbid diseases, and surgical techniques were considered.</p>","PeriodicalId":377573,"journal":{"name":"Retina (Philadelphia, Pa.)","volume":" ","pages":"1465-1471"},"PeriodicalIF":3.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40647354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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