特发性多灶性脉络膜炎伴蛇形样乳头周围脉络膜视网膜萎缩。

Kareem Moussa, Joseph B Alsberge, Marion R Munk, Robin A Vora, Parisa Emami-Naeini, Glenn Yiu, Emmett T Cunningham
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引用次数: 3

摘要

目的:报告9例多局灶性脉络膜炎合并蛇形样乳头周围脉络膜视网膜萎缩。方法:回顾性观察多灶性脉络膜炎伴蛇形样乳头周围脉络膜视网膜萎缩的病例。本文回顾并介绍了多模态影像学结果。结果:9例患者15只眼(女6例,男3例),平均年龄48.1岁(中位46岁;范围,23-74岁),表现为多灶性脉络膜炎,蛇形样乳头周围脉络膜视网膜萎缩。所有15只眼均表现为蛇形样乳头周围改变,并在后极或外周有离散斑块的萎缩或穿孔疤痕。光学相干断层扫描显示锥形视网膜色素上皮升高11眼(73.3%),轻度玻璃体炎10眼(66.7%),周围曲线条纹病变4眼(26.7%)。3眼(20%)有脉络膜新生血管。所有患者对全身免疫抑制、局部皮质类固醇注射和/或玻璃体内注射抗血管内皮生长因子治疗反应良好。结论:多灶性脉络膜炎除了典型的后极或外周斑块萎缩或穿孔疤痕,光学相干断层扫描显示锥形视网膜色素上皮升高和周围曲线条纹病变外,还可能表现为类似蛇形脉络膜样脉络膜炎的乳头周围脉络膜病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
IDIOPATHIC MULTIFOCAL CHOROIDITIS WITH SERPIGINOUS-LIKE PERIPAPILLARY CHORIORETINAL ATROPHY.

Purpose: To report nine cases of multifocal choroiditis with serpiginous-like peripapillary chorioretinal atrophy.

Methods: A retrospective observational case series of eyes with multifocal choroiditis with serpiginous-like peripapillary chorioretinal atrophy. Multimodal imaging findings were reviewed and presented.

Results: Fifteen eyes of 9 patients (6 women and 3 men), with a mean age of 48.1 years (median, 46 years; range, 23-74 years), presented with multifocal choroiditis serpiginous-like peripapillary chorioretinal atrophy. All 15 eyes presented with serpiginoid peripapillary changes and had discrete patches of atrophy or punched-out scars in the posterior pole or periphery. Eleven eyes (73.3%) had cone-shaped retinal pigment epithelium elevations on optical coherence tomography, 10 eyes (66.7%) had mild vitritis, and 4 eyes (26.7%) had peripheral curvilinear streak lesions. Three eyes (20%) had choroidal neovascularization. All patients responded well to treatment with systemic immunosuppression, local corticosteroid injections, and/or intravitreal anti-vascular endothelial growth factor injections.

Conclusion: Multifocal choroiditis may present with peripapillary chorioretinal changes resembling a serpiginous-like choroiditis in addition to the classic findings of patches of atrophy or punched-out scars in the posterior pole or periphery, cone-shaped retinal pigment epithelium elevated on optical coherence tomography and peripheral curvilinear streak lesions.

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