Endocrinologia, Diabetes y Nutricion最新文献

{"title":"Tiroides y reproducción asistida","authors":"Gemma Sesmilo","doi":"10.1016/j.endinu.2024.10.001","DOIUrl":"10.1016/j.endinu.2024.10.001","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 10","pages":"Pages 411-414"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the rs12654778 SNP of the β-2 adrenergic receptor and LDL cholesterol levels in the Chilean adult population","authors":"Carlos González-Contreras ,&nbsp;Miquel Martorell ,&nbsp;Natalia Ulloa ,&nbsp;Carolina Ochoa-Rosales ,&nbsp;Felipe Díaz-Toro ,&nbsp;Fanny Petermann-Rocha ,&nbsp;Carlos Celis-Morales ,&nbsp;Marcelo Villagran ,&nbsp;Lorena Mardones ,&nbsp;on behalf of the ELHOC Group (Epidemiology of Lifestyle and Health Outcomes in Chile)","doi":"10.1016/j.endinu.2024.06.005","DOIUrl":"10.1016/j.endinu.2024.06.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Various polymorphisms in the beta-2 adrenergic receptor (<em>ADRB2</em>) gene have been associated with cardiometabolic risk factors, such as hypertension, dyslipidemia, type 2 diabetes mellitus and obesity contributing to the physiopathology of these chronic conditions. However, the association of the single nucleotide polymorphism (SNP) rs12654778 at the <em>ADRB2</em> gene with metabolic changes has been poorly studied and there is no information on the Chilean adult population.</div></div><div><h3>Objective</h3><div>To investigate the association between the rs12654778 SNP at the <em>ADRB2</em> gene with cardiometabolic risk markers in a Chilean adult population.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study including 404 participants from the GENADIO study whom were genotyped for rs12654778 and categorized into GG, AG, and AA genotypes. Associations with cardiometabolic risk markers, such as blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, blood glucose and insulin were examined using multivariate regression analysis, while statistical models were adjusted for sociodemographic and lifestyle variables.</div></div><div><h3>Results</h3><div>Our findings indicate a significant association between the presence of the protective genotype (AA) of the rs12654778 polymorphism and lower low-density lipoprotein cholesterol levels corresponding to 8.75<!--> <!-->mg/dL per each copy of the protective allele (maximally adjusted model). No significant associations were seen for the remaining variables.</div></div><div><h3>Conclusion</h3><div>The AA genotype of the rs12654778 SNP at the <em>ADRB2</em> gene had a protective effect specifically against low-density lipoprotein cholesterol levels. This is the first study ever conducted in Chile on this SNP of <em>ADRB2</em> and one of the few conducted worldwide to establish an association between the rs12654778 SNP at the <em>ADRB2</em> gene and LDL cholesterol.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 9","pages":"Pages 397-404"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the economic situation and diabetes mellitus, metabolic control and the use of health services in a Spanish region","authors":"Roberto Sánchez Medina ,&nbsp;Alejandro de Arriba Fernández ,&nbsp;Ángela Gutiérrez Pérez ,&nbsp;José Luis Alonso Bilbao","doi":"10.1016/j.endinu.2024.08.004","DOIUrl":"10.1016/j.endinu.2024.08.004","url":null,"abstract":"<div><h3>Introduction</h3><div>The prevalence of diabetes mellitus (DM) has increased in low- and middle-income countries and in marginal areas of developed countries_. In Spain, it grew by 3.42% from 1993 to 2020. In the Canary Islands, the increase was even greater.</div></div><div><h3>Objectives</h3><div>The main one was to evaluate the possible relationship of the income level with DM, different markers of metabolic control and the use of Primary Care services, in Las Palmas de Gran Canaria (LPGC). Secondary ones are to determine the prevalence of DM in the city of LPGC, to describe the sociodemographic characteristics, the use of Primary Care services of the population with DM, the level of registry of variables related to metabolic control and the main process indicators and intermediate results of the metabolic control in the population with DM in the city of LPGC.</div></div><div><h3>Material and method</h3><div>All patients with DM over 14 years of age, living in LPGC as of 12/31/22 were included. Data were collected from the electronic medical records of the Canarian Primary Care Service, the National Institute of Statistics and the National Tax Agency.</div></div><div><h3>Results and conclusion</h3><div>The overall prevalence of DM was 11.39%. The mean age of participants was 67.06 years (SD<!--> <!-->=<!--> <!-->13.86), lower in men than in women. The groups with low or moderate income accounted for more than 40% of the prevalence each, while those with high income barely accounted for 10%. Higher income levels corresponded to lower use of health resources and registration of metabolic variables, while decreasing income levels were associated to higher prevalence of overweight/obesity, worse lipid and glycemic profiles and higher risk of diabetic foot. The middle-income group showed the highest prevalence of pathological/uncertain diabetic retinopathy, lower glomerular filtration and higher LDL levels.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 10","pages":"Pages 427-435"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIABETES MELLITUS (PÓSTERES)","authors":"","doi":"10.1016/S2530-0164(24)00186-1","DOIUrl":"10.1016/S2530-0164(24)00186-1","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 80-111"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"METABOLISMO ÓSEO Y FOSFOCÁLCICO (COMUNICACIONES ORALES)","authors":"","doi":"10.1016/S2530-0164(24)00180-0","DOIUrl":"10.1016/S2530-0164(24)00180-0","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 22-23"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of hypogonadism in men with and without chronic obstructive pulmonary disease: A cross-sectional study","authors":"Horacio Matías Castro ,&nbsp;Pablo Knoblovits ,&nbsp;Joaquin Maritano Furcada ,&nbsp;Eduardo Luis De Vito ,&nbsp;Sebastían Matias Suarez ,&nbsp;Pablo Rene Costanzo","doi":"10.1016/j.endinu.2024.05.010","DOIUrl":"10.1016/j.endinu.2024.05.010","url":null,"abstract":"<div><h3>Background</h3><div>Hypogonadism is a common finding of chronic obstructive pulmonary disease (COPD). However, the prevalence of hypogonadism in COPD varies among studies. The aim of this study was to determine and compare the prevalence of hypogonadism in men with and without COPD.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study with 134 patients with stable COPD and 70 age-matched men with non-COPD. Hypogonadism was defined by the presence of symptoms according to the Androgen Deficiency in Aging Males questionnaire, along with total testosterone deficiency (&lt;300<!--> <!-->ng/dL).</div></div><div><h3>Results</h3><div>Patients had a mean age of 68 years (SD, 6), a body mass index of 28<!--> <!-->kg/m² (SD, 6), and 17% were current smokers. The prevalence of hypogonadism was 41.8% in COPD men (<em>N</em> <!-->=<!--> <!-->56, 95%CI, 33–51) and 10.0% in non-COPD men (<em>N</em> <!-->=<!--> <!-->7, 95%CI, 4–20), with a prevalence ratio of 4.2 (95%CI, 2.0–8.7, <em>p</em> <!-->&lt;<!--> <!-->0.001). The prevalence of low total testosterone concentrations (&lt;300<!--> <!-->ng/dL) were significantly higher in COPD patients vs the control group (47.0% vs 15.7%, <em>p</em> <!-->=<!--> <!-->&lt;0.001). In the COPD group, 89.3% of patients had hypogonadotropic hypogonadism and 10.7%, hypergonadotropic hypogonadism. The prevalence of hypogonadism was higher in severe vs non-severe COPD patients (55.8% vs 35.2%; <em>p</em> <!-->=<!--> <!-->0.024).</div></div><div><h3>Conclusions</h3><div>The prevalence of hypogonadism was high and greater in COPD vs non-COPD men. This study suggests that COPD patients should be screened for hypogonadism.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 8","pages":"Pages 348-354"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OBESIDAD (COMUNICACIONES ORALES)","authors":"","doi":"10.1016/S2530-0164(24)00177-0","DOIUrl":"10.1016/S2530-0164(24)00177-0","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 18-21"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ENDOCRINOLOGÍA BÁSICA Y TRASLACIONAL (PÓSTERES)","authors":"","doi":"10.1016/S2530-0164(24)00182-4","DOIUrl":"10.1016/S2530-0164(24)00182-4","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 25-32"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SUPRARRENALES (COMUNICACIONES ORALES)","authors":"","doi":"10.1016/S2530-0164(24)00173-3","DOIUrl":"10.1016/S2530-0164(24)00173-3","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 4-5"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NEUROENDOCRINOLOGÍA (COMUNICACIONES ORALES)","authors":"","doi":"10.1016/S2530-0164(24)00172-1","DOIUrl":"10.1016/S2530-0164(24)00172-1","url":null,"abstract":"","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"71 ","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}