Endocrinologia, Diabetes y Nutricion最新文献

LO QUE PUEDE APORTAR LA ATENCIÓN PRIMARIA EN EL CRIBADO DE DIABETES TIPO 1 初级保健在1型糖尿病病例中的作用

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-09-30 DOI: 10.1016/j.endinu.2026.501946

Miguel Ángel María Tablado

引用次数: 0

Cardiopatía carcinoide en tumores neuroendocrinos gastroenteropancreáticos: serie clínica y experiencia en práctica real 胃肠胰腺神经内分泌肿瘤的类癌性心脏病：临床系列和实际经验

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-04-08 DOI: 10.1016/j.endinu.2026.501802

Francisco Javier Albacete Zapata, Pedro Iglesias

引用次数: 0

Corrigendum to: Impacto de la semaglutida oral en la calidad de vida y parámetros metabólicos de los pacientes con diabetes mellitus tipo 2: un estudio observacional multicéntrico 更正：口服谷氨酸对2型糖尿病患者生活质量和代谢参数的影响：一项多中心观察研究

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-05-19 DOI: 10.1016/j.endinu.2026.501844

引用次数: 0

Frailty and diabetes: When glycaemic management is no longer the primary objective 虚弱和糖尿病：当血糖管理不再是首要目标时

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-09-09 DOI: 10.1016/j.endinu.2026.501908

Josep Franch-Nadal, Didac Mauricio, Giuseppe Maltese

引用次数: 0

Resumen ejecutivo del documento consenso OSEOSEEN sobre diagnóstico y manejo de las enfermedades óseas raras 关于罕见骨病诊断和管理的OSEOSEEN共识文件执行摘要

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-04-08 DOI: 10.1016/j.endinu.2026.501803

Beatriz García-Fontana, Cristina García-Fontana, María Dolores López Robles, Verónica Ávila-Rubio, Guillermo Martínez Díaz-Guerra, Pilar Rodríguez Ortega, Mariela Varsavsky, María Rosa Alhambra Expósito, Antonia García-Martín, María Cortés-Berdonces, Fernando Marín Díez, Isabel Huguet, Esteban Jódar-Gimeno, Manuel Muñoz-Torres

{"title":"Resumen ejecutivo del documento consenso OSEOSEEN sobre diagnóstico y manejo de las enfermedades óseas raras","authors":"Beatriz García-Fontana, Cristina García-Fontana, María Dolores López Robles, Verónica Ávila-Rubio, Guillermo Martínez Díaz-Guerra, Pilar Rodríguez Ortega, Mariela Varsavsky, María Rosa Alhambra Expósito, Antonia García-Martín, María Cortés-Berdonces, Fernando Marín Díez, Isabel Huguet, Esteban Jódar-Gimeno, Manuel Muñoz-Torres","doi":"10.1016/j.endinu.2026.501803","DOIUrl":"10.1016/j.endinu.2026.501803","url":null,"abstract":"<div><div>Rare bone diseases comprise a heterogeneous group of low-prevalence disorders affecting the development, remodeling, or structural integrity of bone tissue. Despite their individual rarity, their clinical, functional, and psychosocial impact is substantial, particularly due to the diagnostic delay that frequently accompanies these conditions. In order to provide a practical and up-to-date clinical tool to improve the identification, diagnostic approach, and management of these entities, an expert consensus document has been developed. The full and extended version is available in the consensus documents section of the manual of the Spanish Society of Endocrinology and Nutrition (SEEN).</div><div>This executive summary condenses the essential contents of the document, offering an overview of the diseases addressed, their main clinical and diagnostic features, and the recommended therapeutic strategies. It also includes a final table that comparatively summarizes the most relevant aspects of each entity.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"73 8","pages":"Article 501803"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth hormone therapy in Turner syndrome: Do cytogenetic subtypes influence outcomes? 生长激素治疗特纳综合征：细胞遗传学亚型影响预后吗？

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-06-09 DOI: 10.1016/j.endinu.2026.501821

Ingrid-Ioana Herșcovici, Monica Cristina Pânzaru, Georgiana Constantinescu, Letiția Leuștean, Maria-Christina Ungureanu, Cristina Preda, Cristina Rusu

{"title":"Growth hormone therapy in Turner syndrome: Do cytogenetic subtypes influence outcomes?","authors":"Ingrid-Ioana Herșcovici, Monica Cristina Pânzaru, Georgiana Constantinescu, Letiția Leuștean, Maria-Christina Ungureanu, Cristina Preda, Cristina Rusu","doi":"10.1016/j.endinu.2026.501821","DOIUrl":"10.1016/j.endinu.2026.501821","url":null,"abstract":"<div><div>Turner syndrome (TS) is a chromosomal disorder caused by complete or partial loss of one X chromosome, occurring in approximately 1 in 2500 live female births. Short stature, resulting from haploinsufficiency of the short stature homeobox-containing (SHOX) gene, absence of a pubertal growth spurt, and ovarian insufficiency are hallmark features. Recombinant human growth hormone (GH) therapy remains the mainstay of management, increasing adult height by approximately 5–8cm. This review examines how cytogenetic subtypes influence GH response, focusing on 45,X monosomy, mosaicism, and structural abnormalities such as isochromosome Xq and ring X. Patients with 45,X monosomy often show a favorable initial response but a more rapid decline in growth velocity, whereas mosaic patients maintain better long-term outcomes. Structural variants involving Xp loss exhibit similarly attenuated responses. Overall, differences between cytogenetic subtypes tend to diminish over time, with age at therapy initiation, treatment duration, and timing of pubertal induction exerting a greater influence on final height outcomes.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"73 8","pages":"Article 501821"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of pregnancy outcomes in women with type 1 vs type 2 diabetes mellitus: A 10-year retrospective study 1型与2型糖尿病妇女妊娠结局的比较分析：一项10年回顾性研究

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-04-20 DOI: 10.1016/j.endinu.2026.501805

Inês Meira, Juliana Gonçalves, João Menino, Ana Luísa Barbosa, Mafalda Costa, Helena Urbano Ferreira, Sílvia Monteiro, Cristina Gamboa, Gabriela Namora, Sandra Belo, Joana Queirós

{"title":"Comparative analysis of pregnancy outcomes in women with type 1 vs type 2 diabetes mellitus: A 10-year retrospective study","authors":"Inês Meira, Juliana Gonçalves, João Menino, Ana Luísa Barbosa, Mafalda Costa, Helena Urbano Ferreira, Sílvia Monteiro, Cristina Gamboa, Gabriela Namora, Sandra Belo, Joana Queirós","doi":"10.1016/j.endinu.2026.501805","DOIUrl":"10.1016/j.endinu.2026.501805","url":null,"abstract":"<div><h3>Background</h3><div>With the global rise in diabetes mellitus (DM), pregnancies in women with preexisting DM are becoming increasingly common and are associated with a higher risk of adverse outcomes. However, the relative impact of type 1 diabetes mellitus (T1DM) vs type 2 diabetes mellitus (T2DM) remains unclear.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included pregnant women with preexisting DM followed between 2014 and 2024. Demographic, clinical, biochemical, and obstetric data were compared according to DM type. Primary outcomes included maternal complications, fetal growth, and neonatal morbidity.</div></div><div><h3>Results</h3><div>Among 169 pregnancies, 114 (67.5%) involved T1DM and 55 (32.5%), T2DM. Compared with women with T2DM, those with T1DM were younger, had lower body mass index, longer diabetes duration, and a higher prevalence of diabetic retinopathy. They also had higher preconception HbA1c levels and greater gestational weight gain. T1DM was associated with higher odds of retinopathy progression, large-for-gestational-age neonates, and neonatal intensive care unit (NICU) admission, but lower odds of labor dystocia. Rates of miscarriage, preterm birth, hypertensive disorders of pregnancy, and cesarean delivery were similar between groups. Among women with T1DM, excessive gestational weight gain and higher late-pregnancy HbA1c levels were strongly associated with adverse neonatal outcomes.</div></div><div><h3>Conclusions</h3><div>Pregnancies complicated by T1DM showed a higher burden of adverse outcomes than those complicated by T2DM. Glycemic control and gestational weight gain emerged as key modifiable risk factors, underscoring the need for tailored management strategies.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"73 8","pages":"Article 501805"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parálisis del nervio peroneo, una inusual complicación tras cirugía bariátrica: experiencia de una serie de casos clínicos 腹膜神经麻痹，减肥手术后的一种不寻常的并发症：一系列临床病例的经验

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-05-15 DOI: 10.1016/j.endinu.2026.501824

Laura Martínez Suero, Noelia Sánchez-Maroto García, Sara Mera Carreiro, Celia López Nevado, Miguel A. Rubio-Herrera

引用次数: 0

Diabetes atípica y lipodistrofia parcial familiar en portadores de variantes en COL3A1 y PAX4: descripción de una familia COL3A1和PAX4变异携带者中的非典型糖尿病和家族性部分脂质营养不良：家族描述

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-03-03 DOI: 10.1016/j.endinu.2026.501778

Gema Villa López, Clara Marijuan Sánchez, Elena García Fernández, Celestino Rodríguez Jiménez, Miguel León Sanz

引用次数: 0

Valor pronóstico de la bioimpedancia eléctrica en ancianos con riesgo nutricional ingresados en una unidad de convalecencia de un centro de atención intermedia 有营养风险的老年人在中级保健中心康复单位的电生物阻抗预测值

4区医学

Endocrinologia, Diabetes y Nutricion Pub Date : 2026-10-01 Epub Date: 2026-02-26 DOI: 10.1016/j.endinu.2026.501775

Jéssica Martínez Rodríguez, Mateu Serra-Prat, Elisabet Palomera Fanegas

{"title":"Valor pronóstico de la bioimpedancia eléctrica en ancianos con riesgo nutricional ingresados en una unidad de convalecencia de un centro de atención intermedia","authors":"Jéssica Martínez Rodríguez, Mateu Serra-Prat, Elisabet Palomera Fanegas","doi":"10.1016/j.endinu.2026.501775","DOIUrl":"10.1016/j.endinu.2026.501775","url":null,"abstract":"<div><h3>Background</h3><div>Bioelectrical impedance analysis (BIA) is a widely used technique in clinical practice, especially in the field of nutrition. Some of its parameters have been associated with an increased risk of malnutrition, sarcopenia, and mortality.</div></div><div><h3>Aim</h3><div>To evaluate the prognostic value of BIA parameters in elderly people at risk of malnutrition admitted to a convalescent unit.</div></div><div><h3>Methods</h3><div>We conducted an observational and prospective study of older adults at nutritional risk admitted to a convalescent unit, followed from admission to hospital discharge. All of them underwent BIA within the first week of admission. The main outcome measures were in-hospital complications, in-hospital mortality, and length of stay. Nutritional status (GLIM criteria), sarcopenia (EWGSOP2 criteria), and frailty (Frail-VIG criteria) were assessed as well.</div></div><div><h3>Results</h3><div>142 patients (62% men, mean age of 82.5 years (SD, 7.58) were recruited. A total of 57.7% exhibited complications during admission; the mean length of stay was 45.0 days (SD, 24.1), and the in-hospital mortality rate, 11.3%. In women, in-hospital complications and mortality were associated with a lower Phase Angle (PhA) and a higher total body water/fat free mass and extracellular water/intracellular water ratios. Survival was significantly lower when PhA on admission was <4.5° in men and <4.0° in women, as well as when the intracellular water/fat free mass ratio was <0.33 in both sexes.</div></div><div><h3>Conclusions</h3><div>PhA and an imbalance between extracellular and intracellular water are indicators of poor prognosis in elderly patients admitted to a convalescent unit.</div></div>","PeriodicalId":37725,"journal":{"name":"Endocrinologia, Diabetes y Nutricion","volume":"73 8","pages":"Article 501775"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149078514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0