Revista Colombiana de Reumatologia最新文献

{"title":"Síndrome de ASIA (autoinmune/inflamatorio inducido por los adyuvantes): revisión narrativa de la literatura","authors":"","doi":"10.1016/j.rcreu.2023.09.004","DOIUrl":"10.1016/j.rcreu.2023.09.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Adjuvant-induced autoimmune/inflammatory syndrome (ASIA) comprises a spectrum of clinical manifestations associated with exposure to diverse adjuvants that have in common the generation of non-specific autoantibodies and loss of immune tolerance.</p></div><div><h3>Objective</h3><p>This study aimed to develop a narrative review of the literature about the pathogenesis underlying ASIA syndrome, its differentiation from other defined autoimmune diseases, and prospects for future research in this field.</p></div><div><h3>Materials and methods</h3><p>A narrative review of the literature was conducted using Pubmed, Embase, and LILACS. All publications on the subject were included, with no time limit in English and Spanish. Finally, 25 articles published since 1990 were included, from which we reviewed the pathogenesis, diagnostic criteria, and its differentiation from other defined autoimmune processes.</p></div><div><h3>Results</h3><p>The appearance of ASIA syndrome seems to be linked to an individual's genetic predisposition (HLA-DRB1*01 or HLA-DRB4) and is the result of the interaction of external and endogenous factors that trigger autoimmune phenomena. In recent years, physicians have become more aware of the relationship between exposure to adjuvants and the development of underlying signs and symptoms that may correspond to ASIA syndrome. The current evidence supporting its existence is still contradictory. A timely diagnosis requires a multidisciplinary approach and could require immunosuppressive treatment in particular cases.</p></div><div><h3>Conclusions</h3><p>In recent years a relationship between exposure to adjuvants and the appearance of autoimmunity phenomena has been recognized. In clinical practice, physicians can find cases of ASIA syndrome. However, the evidence is still debated on the relationship between adjuvants and autoimmune clinical manifestations. ASIA syndrome classification criteria require validation in various populations before being applied to select patients for clinical studies. It is necessary to identify the risk factors for ASIA syndrome to understand its pathophysiology and make a timely diagnosis.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 380-389"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135509499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe de errores del artículo «Estado actual de la ecografía musculoesquelética en la reumatología colombiana» [Rev Colomb Reumatol. 2023;30(1):4-12]","authors":"Josué Guillermo López-Velandia ,&nbsp;Juliana Higuera-García ,&nbsp;Luis Javier Cajas-Santana","doi":"10.1016/j.rcreu.2024.04.002","DOIUrl":"10.1016/j.rcreu.2024.04.002","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Page 426"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0121812324000483/pdfft?md5=47775a58d756ee737b354a8d11cdf505&pid=1-s2.0-S0121812324000483-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe de errores del artículo «Guía de práctica clínica para la detección temprana, el diagnóstico, el tratamiento y el seguimiento de los pacientes con artritis reumatoide. Asociación Colombiana de Reumatología, 2022» [Rev Colomb Reumatol.2024;31(2):205-222]","authors":"Carlos Enrique Toro-Gutiérrez ,&nbsp;Álvaro Arbeláez-Cortés ,&nbsp;Andrés R. Fernández-Aldana ,&nbsp;Rossana A. Mejía-Romero ,&nbsp;Paul Méndez Patarroyo ,&nbsp;L. Gerardo Quintana ,&nbsp;Oscar O. Ruiz-Santacruz ,&nbsp;Pedro Santos-Moreno ,&nbsp;Daniel G. Fernández-Ávila","doi":"10.1016/j.rcreu.2024.04.005","DOIUrl":"10.1016/j.rcreu.2024.04.005","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 429-430"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0121812324000537/pdfft?md5=6a29da42e87d25d15e4387c25a6e4cbc&pid=1-s2.0-S0121812324000537-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis transitoria del embarazo: serie de casos","authors":"","doi":"10.1016/j.rcreu.2023.01.001","DOIUrl":"10.1016/j.rcreu.2023.01.001","url":null,"abstract":"<div><p>Transient osteoporosis of pregnancy is a pathology of low prevalence and difficult diagnosis that mainly affects pregnant women in the third trimester of pregnancy. It is characterized by mechanical joint pain, more frequent in the lower limbs, radiological osteopenia, and bone oedema on magnetic resonance imaging. A series of 4 cases is presented in pregnant women between 26 weeks of gestation and the early puerperium with symptoms of coxalgia and/or knee pain. The treatment was based on conservative measures: analgesics that are allowed during pregnancy and non-weight bearing on the joints, and the possibility of corticosteroid infiltration into the joint. Bisphosphonates can be added in the puerperium. All cases resolved within a maximum of 9 months, without subsequent sequelae.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 417-423"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46340134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applicability of the MASEI index in enthesis and its association with other indices/serological markers of activity in patients with spondyloarthritis","authors":"","doi":"10.1016/j.rcreu.2023.07.005","DOIUrl":"10.1016/j.rcreu.2023.07.005","url":null,"abstract":"<div><h3>Introduction</h3><p>The enthesis is one of the target organs in patients with spondyloarthritis (SpA), since inflammation of it, known as enthesitis, can be observed, which in many patients with spondyloarthritis could go unnoticed.</p></div><div><h3>Objective</h3><p><span><span>To find the relationship between the MASEI index (MAdrid Sonographic Enthesitis Index) in entheses and other indices/serological activity markers (such as </span>BASDAI, DAPSA or </span>ASDAS and ESR, CRP) in spondyloarthritis patients.</p></div><div><h3>Materials and methods</h3><p>Observational, descriptive, and cross-sectional study. Data were collected from patients with SpA who underwent musculoskeletal ultrasound using the MASEI index and who were treated in our clinics from May 2021 to September 2021. As appropriate, the variables evaluated were described using frequency and central tendency/dispersion measures. First, we tested the normality of all the variables using a Shapiro–Wilk test. Then we studied the correlation of parametric and non-parametric numerical variables, using Pearson's and Spearman's coefficients. We used the <em>T</em>-Student, Mann–Whitney <em>U</em>, and chi-square tests for the categorical variables.</p></div><div><h3>Results</h3><p>We analyzed 24 patients with SpA (with a mean age of 50.50<!--> <!-->±<!--> <!-->10.63 years), 8 women and 16 men. The variables have the following average levels: ASDAS 2.35 (±1.09); BASDAI (for those with axial involvement) 4.54 (±2.93); DAPSA (for psoriatic arthritis) 10.98 (±6.85), and total MASEI 19.88 (±14.77). We found a correlation between the total MASEI and the following variables: ASDAS (Pearson coefficient<!--> <!-->=<!--> <!-->.696), BASDAI (Spearman coefficient<!--> <!-->=<!--> <!-->.823), and DAPSA (Pearson coefficient<!--> <!-->=<!--> <!-->.823).</p></div><div><h3>Conclusion</h3><p>Patients with spondyloarthritis with more significant disease activity measured by ASDAS, BASDAI/DAPSA, and the serological markers of inflammation CRP and ESR present a higher total MASEI than patients who are controlled.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 349-355"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relación clínica entre la artritis reactiva y la infección por SARS-CoV-2: una revisión exploratoria","authors":"","doi":"10.1016/j.rcreu.2023.04.001","DOIUrl":"10.1016/j.rcreu.2023.04.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Reactive arthritis (ReA) is a monoarthritis or oligoarthritis that mainly affects the extremities, it can be related to bacterial or viral infections. Currently, COVID-19 has been linked to the development of arthropathies due to its inflammatory component.</p></div><div><h3>Objective</h3><p>A scoping review of the literature that describes the clinical characteristics of ReA in survivors of SARS-CoV-2 infection.</p></div><div><h3>Materials and methods</h3><p>A systematic review based on the guidelines for reporting systematic reviews adapted for Prisma-P exploratory reviews and steps proposed by Arksey and adjusted by Levan. Experimental and observational studies published in PubMed and Scopus, English and Spanish, which answered the research questions posed, were included.</p></div><div><h3>Results</h3><p>Twenty-five documents were included describing the main clinical manifestations of ReA in 27 patients with a history of SARS-CoV-2 infection. The time from the onset of symptoms or microbiological diagnosis of COVID-19 to the development of articular and/or extra-articular manifestations compatible with ReA ranged from 7 days to 120 days. The clinical joint manifestations described were arthralgia and oedema, predominantly in knee, ankle, elbow, interphalangeal, metatarsophalangeal, and metacarpophalangeal joints.</p></div><div><h3>Conclusions</h3><p>Arthralgias in the extremities are the main symptom of ReA in patients with a history of COVID-19, whose symptoms can present in a period of days to weeks from the onset of clinical symptoms or microbiological diagnosis of SARS-CoV-2 infection.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 390-398"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43486423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recaída en pacientes con vasculitis asociadas a ANCA: un estudio de cohorte en un centro de enfermedades reumatológicas en Colombia","authors":"","doi":"10.1016/j.rcreu.2023.12.005","DOIUrl":"10.1016/j.rcreu.2023.12.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Relapses are common in patients with ANCA-associated vasculitis (AAV), which results in a significant burden of morbidity, mortality, impact on quality of life, disability, and cost. However, evidence in the Colombian population is scarce.</p></div><div><h3>Objective</h3><p>The objective of this study was to estimate the relapse-free survival during the first year and describe clinical and serological variables of patients with AAV in a specialized centre for rheumatic diseases in Colombia.</p></div><div><h3>Materials and methods</h3><p>A retrospective follow-up study was conducted on a cohort based on medical records of patients over 18<!--> <!-->years old with confirmed diagnosis of AAV by the treating rheumatologist and who had achieved remission. Information on AAV relapse and clinical, immunoserological, and treatment-related characteristics was extracted. The relapse-free survival function during the first year was estimated.</p></div><div><h3>Results</h3><p>A total of 56 patients were included, 69.9% of whom were women, with a median age of 60 (IQR<!--> <!-->=<!--> <!-->48-63). According to the clinical phenotype, 64.3% were classified as granulomatosis with polyangiitis (GPA), 23.2% as microscopic polyangiitis (MPA), and 12.5% as eosinophilic granulomatosis with polyangiitis (EGPA). According to the European Vasculitis Study Group (EUVAS) classification, 39.3% had generalized AAV at debut, 23.2% had localized AAV, 21.4% had severe renal AAV, and 16.1% had systemic AAV. The median Five Factor Score (FFS) was<!--> <!-->1 (IQR<!--> <!-->=<!--> <!-->0-2). The cumulative relapse-free survival at one year was 82.2%.</p></div><div><h3>Conclusions</h3><p>The relapse-free survival observed in this cohort was similar to other reports in clinical studies and AAV registries.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 318-326"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139966703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe de errores del artículo «Diagnóstico de sarcoidosis a partir de compromiso ocular. Reporte de caso» [Rev Colomb Reumatol. 2024;31(1):88-92]","authors":"Juan Camilo Cadavid Usuga ,&nbsp;Mónica Ortiz Pérez ,&nbsp;Marcos Restrepo Arango ,&nbsp;Ana María Montufar Pantoja","doi":"10.1016/j.rcreu.2024.04.003","DOIUrl":"10.1016/j.rcreu.2024.04.003","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Page 427"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0121812324000513/pdfft?md5=38aedd7b99f619d7e814df8d2b7828c3&pid=1-s2.0-S0121812324000513-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse alveolar hemorrhage secondary to anti-synthetase syndrome","authors":"","doi":"10.1016/j.rcreu.2023.11.006","DOIUrl":"10.1016/j.rcreu.2023.11.006","url":null,"abstract":"<div><h3>Introduction</h3><p>Alveolar hemorrhage syndrome can be secondary to multiple autoimmune disorders. The objective is to describe three diffuse alveolar hemorrhage (DAH) cases secondary to anti-synthetase syndrome (ASSD).</p></div><div><h3>Presentation of the case</h3><p>Three cases of ADH secondary to ASSD are described: one positive to anti-PL7, another positive to anti-PL12, and the last patient with double positivity to anti-Jo1 and anti-OJ. The patients presented improvement after receiving immunosuppressive treatment.</p></div><div><h3>Discussion</h3><p>The evolution with therapeutic response and resolution of DAH supports the conclusion that ASSD is a potentially treatable cause of DAH and should be considered within the differential diagnosis in diagnosing DAH.</p></div><div><h3>Conclusion</h3><p>The described cases contribute to the knowledge of DAH, where ASSD should be considered in diagnosing DAH.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 412-416"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desenlaces con el uso de rituximab en pacientes con nefritis lúpica refractaria en una cohorte colombiana","authors":"Julián Barbosa-Arana ,&nbsp;Juan David López-López ,&nbsp;Sebastián Guerra-Zarama ,&nbsp;Santiago Monsalve-Yepes ,&nbsp;María Fernanda Saavedra-Chacón ,&nbsp;José David Serna-Giraldo ,&nbsp;Juan Camilo Díaz-Coronado ,&nbsp;Diego Fernando Rojas-Gualdron ,&nbsp;Deicy Hernandez-Parra ,&nbsp;Sebastián Herrera","doi":"10.1016/j.rcreu.2022.07.006","DOIUrl":"10.1016/j.rcreu.2022.07.006","url":null,"abstract":"<div><h3>Introduction/Objective</h3><p>To describe the safety and response to treatment with rituximab (RTX), estimating its impact on the health state utility (HSU) of patients with refractory lupus nephritis (LN) treated in referral centres in several cities in Colombia.</p></div><div><h3>Materials and methods</h3><p>A registry-based follow-up study. Patients aged between 16 and 75<!--> <!-->years, who were refractory to first-line management and had ISN/RPS class III-IV (±<!--> <!-->V) LN, were included. Our primary outcome was total or partial response to treatment; secondary outcomes were HSU measured with the EQ-5D-3L, and safety of treatment with RTX. The impact analysis of response to RTX on HSU were performed by mean difference estimated by robust regression.</p></div><div><h3>Results</h3><p>Forty-six patients (44 women) were included, with a median age of 34<!--> <!-->years (IQR<!--> <!-->=<!--> <!-->13), the median SDI was<!--> <!-->1 (IQR<!--> <!-->=<!--> <!-->1) and the median activity measured by SLEDAI was 4.5 (IQR<!--> <!-->=<!--> <!-->5.9). Response to RTX was observed in 27 (58.7%) patients. Adjusted for SLEDAI and co-interventions, the patients who responded to RTX obtained a higher mean HSU by 0.162 (95%<!--> <!-->CI: 0.006-0.317). Which is equivalent to 1.9 (95%<!--> <!-->CI: 0.2-3.8) more months lived in ideal health conditions for each year with refractory LN. In 54.3% of the patients, RTX had adequate safety.</p></div><div><h3>Conclusion</h3><p>From the patient's perspective, the response to treatment with RTX in patients with refractory LN implies a significant impact on their quality of life.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 2","pages":"Pages 143-149"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47304851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}