Obstetrics and Gynecology Science最新文献

{"title":"KSMFM factsheet on obstetric complications after myomectomy or adenomyomectomy: uterine rupture and placenta accreta spectrum.","authors":"Seung Yeon Pyeon, Hayan Kwon, Hyeon Ji Kim, Ho Yeon Kim, Ji-Hee Sung, Gi Su Lee, You Jung Han, Hyun-Joo Seol, Joong Shin Park","doi":"10.5468/ogs.26214","DOIUrl":"https://doi.org/10.5468/ogs.26214","url":null,"abstract":"<p><p>Over the past 20 years, as the number of women of reproductive age in Korea diagnosed with uterine leiomyoma and adenomyosis prior to pregnancy has increased, fertility-preserving uterine surgeries such as myomectomy and adenomyomectomy have also increased. Although these surgeries can preserve fertility, they can cause serious obstetric complications, such as uterine rupture and placenta accreta spectrum (PAS). The incidence of uterine rupture after myomectomy is reported to be 0.5-1.52%, whereas the incidence after adenomyomectomy is considerably higher, ranging from 3.2 to 12.5%. A key clinical characteristic is that rupture can occur before labor regardless of gestational age, making clinical prediction difficult. Furthermore, myomectomy and adenomyomectomy carry a high risk of PAS, which can lead to severe maternal and neonatal morbidity. Therefore, women of childbearing age should receive sufficient counseling before deciding on surgery and undergo thorough prenatal care throughout pregnancy.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal vitamin D status, deficiency prevention strategies, and perinatal health outcomes.","authors":"Jaeyoung Pae, Ji Young Kwon","doi":"10.5468/ogs.26149","DOIUrl":"https://doi.org/10.5468/ogs.26149","url":null,"abstract":"<p><p>Adequate maternal nutrition is vital for fetal development and maternal health. Although vitamin D is a widely utilized prenatal supplement, its clinical efficacy in improving major pregnancy outcomes remains a topic of debate. This study reviewed the physiological roles of vitamin D, evaluated the clinical impact of maternal supplementation on perinatal indices, and provided practical clinical recommendations within the context of regional public health challenges. Although observational data have consistently associated low maternal 25-hydroxyvitamin D levels with adverse outcomes, interventional evidence from randomized controlled trials (RCTs) regarding the preventive effects of vitamin D supplementation on major obstetric complications, including preeclampsia, gestational diabetes mellitus, and preterm birth, remains limited, highly variable, and condition-specific. A high prevalence of vitamin D deficiency has been reported among women of childbearing age in South Korea, highlighting the importance of maternal vitamin D status from a public health perspective. For pregnant women with confirmed or suspected deficiency, a daily regimen of 1,000-2,000 IU may help achieve adequate maternal vitamin D status, taking into account dietary intake, food fortification, and prenatal vitamin use. However, the existing evidence does not support universal vitamin D supplementation solely for the prevention of major obstetric complications. Future research should shift toward precision medicine by conducting large-scale RCTs stratified by maternal body mass index, genetic polymorphisms, and behavioral and environmental factors, including smoking and sunlight exposure.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum cathepsin B and D levels in pregnancy in Ngoerah Hospital: a cross sectional study.","authors":"Anak Agung Ngurah Jaya Kusuma, Endang Sri Widiyanti, I Nyoman Wande, Khanisyah Erza Gumilar, Fransiscus Ronaldo, I Gusti Agung Ari Wiweka Nanda","doi":"10.5468/ogs.26093","DOIUrl":"https://doi.org/10.5468/ogs.26093","url":null,"abstract":"<p><strong>Objective: </strong>Cathepsins are lysosomal proteases involved in extracellular matrix remodeling, angiogenesis, and immune regulation. Evidence on serum cathepsin B (Cat B) and cathepsin D (Cat D) levels during pregnancy remains limited and inconsistent, particularly in the Balinese population. This study compared serum Cat B and Cat D levels across pregnancy trimesters and in nonpregnant women.</p><p><strong>Methods: </strong>This analytical cross-sectional study included 96 women, with 24 participants in each group: first trimester, second trimester, third trimester, and nonpregnant controls. Serum Cat B and Cat D levels were measured using enzyme-linked immunosorbent assay. Data were analyzed using one-way analysis of variance or the Kruskal-Wallis test, followed by post hoc analysis.</p><p><strong>Results: </strong>Baseline characteristics were comparable across groups. Serum Cat B levels were significantly higher in pregnant women than in nonpregnant controls (P=0.002). Post hoc analysis confirmed significantly higher Cat B levels in all trimesters than in nonpregnant women, with no significant differences among trimesters. Cat D levels were not normally distributed (P<0.001). Median Cat D levels were highest in the third trimester (P<0.001), whereas no significant differences were observed among the other three groups.</p><p><strong>Conclusion: </strong>Cat B levels were elevated throughout pregnancy without trimester-specific variation, whereas Cat D levels increased markedly in the third trimester. The trimester-related patterns observed in this study are consistent with previous findings; however, absolute Cat B and Cat D levels differed across populations. Further studies are warranted to clarify the mechanistic and endocrine associations of these biomarkers during pregnancy.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Placental caspase-3 expression in preeclampsia: a systematic review of observational evidence.","authors":"Graciella Angelica Lukas, Wisnu Prabowo, Annisa Aghnia Rahma, Maurilla Iascha Suhartono, Hidayat Fatahillah, Hikam Yanwar Pradana, Muhana Fawwazy Ilyas, Matthew Aldo Wijayanto","doi":"10.5468/ogs.25360","DOIUrl":"https://doi.org/10.5468/ogs.25360","url":null,"abstract":"<p><p>Preeclampsia is a pregnancy disorder that contributes substantially to maternal and fetal morbidity and mortality worldwide. Apoptosis has been implicated in its pathogenesis, particularly in placental dysfunction. Caspase-3, an executioner caspase, mediates the final stage of apoptotic signaling; however, its role in preeclampsia remains incompletely defined. This systematic review evaluated observational evidence on placental caspase-3 expression in preeclampsia. PubMed, Scopus, and ScienceDirect were systematically searched on June 21, 2024. Eligible studies were human observational studies that assessed caspase-3 expression in placental tissue from pregnancies complicated by preeclampsia. Risk of bias was evaluated using the Newcastle-Ottawa Scale and the Risk of Bias Assessment Tool for Nonrandomized Studies 2.0 (RoBANS 2.0; COMPANY, CITY, STATE, COUNTRY). Data were synthesized qualitatively because of substantial methodological heterogeneity. Twelve studies (n=736 pregnancies) were included. All assessed caspase-3 expression in placental tissue obtained after delivery. Most reported higher caspase-3 expression in preeclamptic placentas than in normotensive controls, particularly in early-onset and severe preeclampsia. However, the studies varied substantially in diagnostic subtypes, measurement methods (including immunohistochemistry scoring systems, Western blotting, and enzyme-linked immunosorbent assay), and control of confounding variables. Observational evidence consistently indicates increased placental caspase-3 expression in preeclampsia, supporting enhanced apoptotic activity in affected placentas. However, because measurements were performed after delivery and caspase-3 is a downstream executioner caspase, current evidence supports its use as a marker of established placental injury. Further mechanistic and longitudinal studies are needed.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-port robot-assisted repair of cesarean scar defect using the da Vinci SP system with near-infrared and simultaneous multi-image display for precise defect localization and excision.","authors":"Masafumi Nii, Hideaki Yajima, Shunichiro Tsuji, Satoshi Tanimura, Yusuke Sako, Kenta Yoshida, Mikiko Nishioka, Erina Takayama, Eiji Kondo, Tomoaki Ikeda","doi":"10.5468/ogs.26062","DOIUrl":"10.5468/ogs.26062","url":null,"abstract":"<p><strong>Objective: </strong>To present a detailed surgical video demonstrating the single-port (SP) robot-assisted repair of a cesarean scar defect (CSD) using the da Vinci SP system (Intuitive Surgical, Sunnyvale, CA, USA), with particular emphasis on hysteroscopic and near-infrared imaging guidance for accurate localization and excision of the defect.</p><p><strong>Methods: </strong>This case report describes a patient with symptomatic CSD who underwent SP robot-assisted repair using the da Vinci SP system (Intuitive Surgical). Concurrent hysteroscopy was performed to delineate the isthmocele from the uterine cavity and to support intraoperative orientation. Near-infrared imaging was performed to visualize the defect on the abdominal side. Because near-infrared imaging alone may not sufficiently define the true excision margin, a simultaneous multi-image display was used to enable real-time correlation between the hysteroscopic and intra-abdominal views. The excision line was carefully determined on the basis of this combined visualization, followed by controlled resection of the fibrotic tissue and multilayer uterine reconstruction.</p><p><strong>Results: </strong>The video illustrates each procedural step, including SP access, bladder dissection, hysteroscopy-assisted identification of the defect, near-infrared-guided marking of the resection margin, precise excision, and secure multilayer uterine closure. The combined visualization approach facilitated clear intraoperative orientation and identification of the defect margin, allowing precise excision and repair of the CSD while maintaining cosmetic integrity.</p><p><strong>Conclusion: </strong>This video provides an educational demonstration of a feasible SP robot-assisted technique for CSD repair. The integration of hysteroscopy and near-infrared imaging with a simultaneous multi-image display may assist in intraoperative decision-making and support precise excision and reconstruction in minimally invasive CSD surgery.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"375-379"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal androgen concentration cut-off values for identifying abnormal insulin sensitivity in Korean women with polycystic ovary syndrome.","authors":"Seula Lee, Hyeonjun An, Soojin Oh, Sungwook Chun","doi":"10.5468/ogs.26004","DOIUrl":"10.5468/ogs.26004","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the relationship between serum androgen concentrations and validated insulin sensitivity indices in Korean women with polycystic ovary syndrome (PCOS) and established optimal androgen thresholds for identifying abnormal insulin sensitivity.</p><p><strong>Methods: </strong>A total of 180 Korean females aged 18-35 years with newly diagnosed PCOS were enrolled. Fasting-state insulin sensitivity assessment indices (ISAIs) were calculated and participants with abnormal levels according to at least one established ISAI criterion were classified as having abnormal insulin sensitivity. Spearman's correlation analysis assessed relationships between insulin sensitivity parameters and four androgens: total testosterone (TT), free testosterone (FT), dehydroepiandrosterone sulfate (DHEA-S), and 17α-hydroxyprogesterone (17-OHP). Receiver operating characteristic (ROC) curve analysis was used to define the most accurate androgen cutoff values for predicting abnormal insulin sensitivity.</p><p><strong>Results: </strong>Among the four androgens tested, TT, FT, and DHEA-S showed significant associations with most insulin resistance (IR) parameters, whereas 17-OHP showed no significant correlation. In the ROC curve analysis, only FT achieved moderately accurate predictive performance (area under the curve [AUC], 0.759), while TT, DHEA-S, and 17-OHP showed AUC values indicating less accurate predictions. The optimal FT cutoff to detect abnormal insulin sensitivity was 1.325 pg/mL (sensitivity, 77.8%; specificity, 64.0%).</p><p><strong>Conclusion: </strong>FT showed the strongest association with parameters related to insulin sensitivity and could serve as a complementary opportunistic indicator of IR in PCOS. Women with PCOS who had serum FT levels ≥1.325 pg/mL were identified as having abnormal insulin sensitivity.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"328-336"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148457053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of endometriosis on the outcomes of assisted reproductive technology in poor ovarian responders with previous implantation failures.","authors":"Soojin Oh, Seula Lee, Sungwook Chun, Tae Woo Park, Jae Hong Joo, Yun Hee Koo, Yong Chan Lee","doi":"10.5468/ogs.26164","DOIUrl":"10.5468/ogs.26164","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether endometriosis (EMS) adversely affects the embryological and clinical outcomes of assisted reproductive technology (ART) in poor ovarian responders (PORs) with repeated implantation failure undergoing spindle view-assisted intracytoplasmic sperm injection (SV-ICSI).</p><p><strong>Methods: </strong>This retrospective study included women aged 35-44 years who underwent ART with SV-ICSI at a single fertility center between January 2023 and December 2024. All participants fulfilled the Bologna criteria for POR and had experienced at least three previous failed embryo transfer cycles. Patients with laparoscopically confirmed EMS were assigned to the EMS group (n=36), whereas age-matched patients without a history or ultrasonographic evidence of EMS were selected as controls in a 1:3 ratio (n=108).</p><p><strong>Results: </strong>The baseline characteristics were comparable between the two groups. No significant differences were observed between the EMS and control groups in key embryological parameters including fertilization rate, cleavage rate, good-quality cleavage embryo rate, and blastocyst formation rate. Similarly, ART-related clinical outcomes did not differ significantly between the two groups, including implantation rate (13.0% vs. 11.7%), clinical pregnancy rate (19.4% vs. 18.5%), and clinical abortion rate (28.6% vs. 40.0%).</p><p><strong>Conclusion: </strong>In this retrospective cohort of patients with POR with repeated implantation failure, no statistically significant association was found between EMS and embryological or ART-related clinical outcomes. However, given the limited sample size and reliance on surrogate reproductive endpoints, these findings should be considered preliminary and hypothesis generating and require confirmation in larger prospective studies incorporating live birth outcomes.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"347-356"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of glycated hemoglobin levels for large for gestational age infants in women with pregestational diabetes according to body mass index.","authors":"Sujin Lee, Suyeon Park, Ji-Hee Sung, Hyun-Joo Seol, JoonHo Lee, Seung-Chul Kim, Sae-Kyoung Choi, Seung Mi Lee, Se Jin Lee, Han-Sung Hwang, Gi-Su Lee, Hyun-Soo Park, Soo-Jeong Lee, Geum Joon Cho, Subeen Hong, Hyun Sun Ko","doi":"10.5468/ogs.26123","DOIUrl":"10.5468/ogs.26123","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether pre-pregnancy body mass index (BMI) modifies the predictive ability of glycosylated hemoglobin (HbA1c) for large for gestational age (LGA) infants in women with pregestational diabetes.</p><p><strong>Methods: </strong>This multicenter retrospective cohort study included 402 women with pregestational diabetes from 17 University Hospitals in South Korea. Pregestational diabetes included early-diagnosed gestational diabetes, type 1 diabetes, and type 2 diabetes. Participants were categorized by pre-pregnancy BMI (<25 vs. ≥25 kg/m2). The primary outcome was LGA birth. Logistic regression was used to assess the association between trimester-specific HbA1c levels and LGA in each BMI group. Receiver operating characteristic (ROC) curve analysis evaluated predictive performance.</p><p><strong>Results: </strong>Among 402 women, 183 (45.5%) had a BMI <25 kg/m2 and 219 (54.5%) had a BMI ≥25 kg/m2. In the BMI <25 kg/m2 group, higher HbA1c levels in all trimesters were significantly associated with an increased risk of LGA, with the strongest association in the third trimester (odds ratio [OR], 2.28; 95% confidence interval [CI], 1.46-3.58). In women with BMI ≥25 kg/m2, only third-trimester HbA1c was significantly associated with LGA (OR, 1.455; 95% CI, 1.069-1.981). ROC analysis showed moderate discrimination for LGA prediction in women with BMI <25 kg/m2 (area under the curve [AUC], 0.70-0.82), but poor discrimination in those with BMI ≥25 kg/m2 (all AUCs ≤0.65).</p><p><strong>Conclusion: </strong>The predictive utility of HbA1c for LGA differed according to pre-pregnancy BMI and was greater in women with BMI <25 kg/m2 than in those with BMI ≥25 kg/m2.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"305-316"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual effects of anti-Müllerian hormone on ovarian response and fertilization in assisted reproductive technology cycles: a retrospective cohort study.","authors":"Hyo-Jin Park, Jae-Hong Joo, Yun Hee Koo, Yong-Chan Lee, Jaewon Lee, Kwang-Yong Kim, Deog-Bon Koo","doi":"10.5468/ogs.26089","DOIUrl":"10.5468/ogs.26089","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the dual effects of anti-Müllerian hormone (AMH) on ovarian response, fertilization outcomes, and clinical pregnancy in assisted reproductive technology (ART) cycles.</p><p><strong>Methods: </strong>This retrospective cohort study screened 6,312 in vitro fertilization or intracytoplasmic sperm injection cycles performed between 2018 and 2023. After excluding cycles with missing AMH or body mass index (BMI) values, non-ART cycles, and extreme BMI values (<18 or ≥45 kg/m2), 4,399 cycles were included. AMH level, age, and BMI were evaluated as independent variables. Ovarian response (retrieved oocyte count) and normally fertilized embryos (two pronuclei) were analyzed using multivariable linear regression and clinical pregnancy was evaluated using logistic regression.</p><p><strong>Results: </strong>AMH level showed a strong positive association with ovarian response (β=2.348; P<0.001), whereas age showed a significant negative association. After adjusting for age, BMI, fertilization method, and retrieved oocytes, AMH level showed a small but significant negative association with fertilized embryo count (β=-0.044; P=0.027). In the subgroup analysis, cycles with AMH ≥10 ng/mL showed higher oocyte yield but lower fertilization (0.561 vs. 0.694; P<0.001) and clinical pregnancy rates (5.7% vs. 23.10%; P<0.001) than those with AMH <10 ng/mL. Increasing age and AMH levels were independently associated with reduced odds of clinical pregnancy.</p><p><strong>Conclusion: </strong>AMH may reflect ovarian reserve quantity rather than optimal reproductive potential, showing a positive association with oocyte yield, but a negative association with fertilization and clinical pregnancy outcomes in ART cycles.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"337-346"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal anxiety and depression screening and psychiatric care linkage in a regional Korean obstetric setting.","authors":"Rina Kim, Soon Sup Shim, Hye Sim Kang","doi":"10.5468/ogs.26124","DOIUrl":"10.5468/ogs.26124","url":null,"abstract":"<p><strong>Objective: </strong>Real-world data on perinatal mental health screening and psychiatric care linkage in regional obstetric populations are limited. This study evaluated screening positivity rates for anxiety and depression during pregnancy and the post-partum period and assessed psychiatric service utilization in a regional Korean obstetric setting.</p><p><strong>Methods: </strong>Pregnant and postpartum women who visited an obstetric clinic between December 2021 and January 2023 were examined in this retrospective, single-center study. Anxiety and depression were evaluated using the Korean versions of the Beck Anxiety Inventory and Edinburgh Postnatal Depression Scale (EPDS). Screening assessments were categorized according to the gestational stage (first, second, and third trimesters) and postpartum period.</p><p><strong>Results: </strong>Of the 445 women included in this study, 235 underwent at least one screening assessment during pregnancy. Among them, 33.2% and 17.9% screened positive for anxiety and depression, respectively, at least once. All 445 women completed the postpartum screening, and 23.6% and 22.9% screened positive for anxiety and depression, respectively. In the exploratory multivariable analysis, neonatal birth weight <1.5 kg remained associated with positive postpartum EPDS screening results. Among the women referred for psychiatric evaluation, only 10.6% attended an initial psychiatric consultation.</p><p><strong>Conclusion: </strong>Positive anxiety and depression screening results were identified during routine perinatal care, whereas psychiatric service utilization remained low. These findings highlight the gap between anxiety and depression screening and psychiatric care linkage, supporting the need for integrated perinatal mental health referral systems.</p>","PeriodicalId":37602,"journal":{"name":"Obstetrics and Gynecology Science","volume":" ","pages":"317-327"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}