MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS最新文献_第2页

Successful Utilization of Poly-4-Hydroxybutyrate Mesh in High Risk, Complex Abdominal Wall Reconstructions with Photo-Microscopic Analysis. 聚4-羟基丁酸酯补片在高危、复杂腹壁重建中的成功应用及其显微分析。

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2021-09-30 DOI: 10.52106/2766-3213.1031

A. Fathi, Joshua Ladella, S. Pooya, D. Slater, J. Bilello

{"title":"Successful Utilization of Poly-4-Hydroxybutyrate Mesh in High Risk, Complex Abdominal Wall Reconstructions with Photo-Microscopic Analysis.","authors":"A. Fathi, Joshua Ladella, S. Pooya, D. Slater, J. Bilello","doi":"10.52106/2766-3213.1031","DOIUrl":"https://doi.org/10.52106/2766-3213.1031","url":null,"abstract":"Background: Biosynthetic resorbable mesh offers encouraging alternative for reinforcement in complex hernia repairs. This study evaluated outcomes of P4HB, absorbable polymer scaffold, in high-risk patients undergoing complex abdominal hernia repairs. Materials and Methods: This is a retrospective outcomes analysis of a prospectively kept database. Patient/wound characteristics, perioperative findings, short/mid-term outcomes of our cohort were analyzed. Endpoints included hernia recurrences, wound events and any complications. ACS NSQIP online risk calculator was used for each patient to obtain predicted outcomes as virtual matched control group. We also performed a full-thickness abdominal wall biopsy at 14-months post mesh implantation for histologic evaluation. Results: 28 patients with mean age 57 years and mean BMI 31 were analyzed. 21 patients (75%) had preexisting infections. 20 (71%) of patients had class I wounds per CDC classification at time of surgery. However, 19 of these 20 had wound or deep organ/space infections prior to surgery. Repair types included restoration of Linea Alba with retromuscular mesh placement in 23 patients (82%) with 22 of them requiring additional myofascial release. 5 patients (18%) had only mesh placement. Postoperatively, 11 patients (39%) had complications with zero hernia recurrence and zero mesh explantation at maximum of 42 months of follow up. Conclusion: P4HB can be successfully used in high-risk operative fields with no postoperative mesh explantation, despite serious complications such as infected hematomas. Histologic evaluation of the human tissue, 14-months post-implantation of P4HB confirms mesh presence with surrounding dense collagen scaffold formation and minimal inflammatory response.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128459156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Collateral Effects of COVID-19 on Non-Communicable Diseases Among Minority Populations COVID-19对少数民族非传染性疾病的附带影响

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2021-09-30 DOI: 10.52106/2766-3213.1028

H. O’Lawrence, L. Martinez, Christine Nguyen

引用次数: 0

A Study About Development of The Reticular Fibers Under the Nail in Human Embryos. 人胚胎指甲下网状纤维发育的研究。

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2021-09-30 DOI: 10.52106/2766-3213.1029

Y. Kishi, Naoshi Hashimoto

{"title":"A Study About Development of The Reticular Fibers Under the Nail in Human Embryos.","authors":"Y. Kishi, Naoshi Hashimoto","doi":"10.52106/2766-3213.1029","DOIUrl":"https://doi.org/10.52106/2766-3213.1029","url":null,"abstract":"This study demonstrates the formation of reticular fibers under fetus nail during the nail development. The seventy-one digits of human fetus had been kept in the buzan stein in the department of the second Anatomy since 1970. They were amputated to measure the length and checked the shape. Then paraffin fixation method was performed. While the nail was formed, we observed using H-E stein and PAM stein how the reticular fibers under the nail were produced. In the early stage of nail formation, the basal layer of the epidermis was positive in PAM stein from matrix and nail bed. Under the basal layer the reticular fibers also were dyed like an arched bridge from the tip of distal phalanx before the matrix primordium was formed. Within the period after the matrix proximordium was produced, the reticular fibers developed under the nail bed especially at the two parts. One part is between the distal phalanx and the matrix primordium. The other is between the tip of distal phalanx and the distal groove. These fibers became thick gradually. In our study, the nail bed and matrix were constantly positive in PAM stein during nail formation. It shows that the nail bed and matrix make the reticular fibers during the nail developmental stage. The ridged connection between the tip of the nail and the distal phalanx is made by the reticular fibers.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126707264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cryptococcus Pneumonia Masquerading as Primary Lung Cancer 伪装成原发性肺癌的肺炎隐球菌

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2021-09-30 DOI: 10.52106/2766-3213.1030

Sweidan Aj, Bota Pg, L. J

引用次数: 0

A Modified Enhanced Recovery Pathway after Pancreaticoduodenectomy: Full Liquids on Discharge 胰十二指肠切除术后改良的增强恢复途径:排出充分液体

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-12-31 DOI: 10.2139/ssrn.3456887

George Younan, A. Jindal, M. Andrews, Danielle Eganhouse, T. Shaver

{"title":"A Modified Enhanced Recovery Pathway after Pancreaticoduodenectomy: Full Liquids on Discharge","authors":"George Younan, A. Jindal, M. Andrews, Danielle Eganhouse, T. Shaver","doi":"10.2139/ssrn.3456887","DOIUrl":"https://doi.org/10.2139/ssrn.3456887","url":null,"abstract":"Background: After success in many surgical disciplines, enhanced recovery after surgery pathways have been recently introduced to the care of patients after pancreatic surgery. The aim of this study is to share our improved outcomes with a modified pathway that allows patients to be discharged home on a full liquid diet. Methods: A modified enhanced recovery pathway was based on published guidelines but included new changes aiming to improve outcomes after pancreaticoduodenectomy in a total of 60 consecutive patients. Results: Patients included in this study had no significant differences in demographics and preoperative characteristics. By implementing a modified enhanced recovery protocol, we were able to improve post-operative parameters, including a decrease in the length of stay to a median of 5 days. Compliance rate with the program reached 88% and patients were able to maintain a similar weight compared to the regular pathway at 30 days. Time to adjuvant therapy was reduced without significantly increasing overall complications or readmission rates. Conclusion: A modified enhanced recovery pathway after pancreaticoduodenectomy successfully improved short-term outcomes and reduced hospital stay.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128263439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved Pancreaticoduodenectomy Outcomes after Starting a Specialized Community Hospital Pancreatic Surgery Program 社区医院胰外科项目实施后胰十二指肠切除术效果的改善

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-12-31 DOI: 10.52106/2766-3213.1011

George Younan, M. Andrews, U. Rangarajan, Danielle Eganhouse, R. Ahmed, T. Shaver

{"title":"Improved Pancreaticoduodenectomy Outcomes after Starting a Specialized Community Hospital Pancreatic Surgery Program","authors":"George Younan, M. Andrews, U. Rangarajan, Danielle Eganhouse, R. Ahmed, T. Shaver","doi":"10.52106/2766-3213.1011","DOIUrl":"https://doi.org/10.52106/2766-3213.1011","url":null,"abstract":"Background: Recent trends in centralization of pancreatic surgery happened as a response to improved outcomes in tertiary care institutions. The volume-outcome relationship is true for high volume hospitals and surgeons. Obstacles to patient travelling to high volume institutions and widespread quality care in community hospitals led to establishing a quality specialized pancreatic surgery program in the community. Methods: Two pancreatic surgery specialists relocated their program from a tertiary care center to a community hospital. Results of the first sixty-two pancreaticoduodenectomy and total pancreatectomy procedures were studied. Results: One hundred and seventeen pancreatic surgery cases were analyzed, sixty-two pancreaticoduodenectomy and total pancreatectomy cases were included. Patient demographics were not different in regard to the median age (67 vs. 62 years), gender (65 vs. 62% males), median BMI (26.2 vs. 26 kg/m2), or American Society of Anesthesiologists class, in between the two hospitals. There was a significant decrease in the operative time (350 vs. 281 minutes, p=0.0001), estimated blood loss (409 vs. 156 milliliters, p=0.003), and length of hospital stay (7.2 vs. 5.2 days, p=0.0001). Most patients were operated on for a diagnosis of malignancy (74.2%), and the R0 resection rate was better at the community hospital reaching 95.2%. Transfusions, delayed gastric emptying and leaks tended to be better at the community hospital but did not reach statistical significance. Conclusion: With dedicated institutional support and careful program design, complex procedures such as PD can be successfully relocated to the community where superior results can be achieved.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126580675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Pandemic and Yoga practice -New prescription for Stress Reduction? COVID-19大流行和瑜伽练习-减轻压力的新处方?

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-12-31 DOI: 10.52106/2766-3213.1012

Vini Vijayan, N. Sukesh, D. Asokan, A. Premkumar, S. Sukumaran

{"title":"COVID-19 Pandemic and Yoga practice -New prescription for Stress Reduction?","authors":"Vini Vijayan, N. Sukesh, D. Asokan, A. Premkumar, S. Sukumaran","doi":"10.52106/2766-3213.1012","DOIUrl":"https://doi.org/10.52106/2766-3213.1012","url":null,"abstract":"The emergence of COVID 19 pandemic since December 31 2019, and isolation of novel SARS-CoV-2 changed the world. Since then, cases have spread all over the globe including 213 Countries/ territories. As the coronavirus spreads throughout the world, so has the ramifications of its spread impacted every aspect of our daily lives. While the physical, economic and social consequences of this pandemic have been enormous, its toll on the mental health and stress level of the general public is especially significant and should be addressed. Mandatory stay at home orders, social distancing measures, the closure of schools, parks, visitation in nursing homes, while necessary to contain the spread, may additionally lead to declining mental health. The latest statistics show that a whopping 264 million individuals worldwide suffer from clinical depression. We propose the use of some simple Yoga practices to cope with this stressful situation and also to address the immune boosting effect of this practice. Proper practice of Yoga assists in mental clarity as well as emotional and physical control. It also helps with stress relief and increases one’s awareness of the physical body rhythms. In this article we address simple Yoga and how to practice it with illustrations. We discuss the available literature regarding Yoga and its benefit in stress and immune-boosting.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"19 S1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121926684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and Sickle Cell Disease in PICU: Case Report COVID-19与PICU中的镰状细胞病:1例报告

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-12-30 DOI: 10.52106/2766-3213.1015

LetÃcia de Paula Tonial, B. Miranda, Joelmy Robert Beleza da Silva, Claudia Moreira de Sousa, Valeria Cabral Neves Luszcynski, A. Koliski, M. Rodrigues

{"title":"COVID-19 and Sickle Cell Disease in PICU: Case Report","authors":"LetÃcia de Paula Tonial, B. Miranda, Joelmy Robert Beleza da Silva, Claudia Moreira de Sousa, Valeria Cabral Neves Luszcynski, A. Koliski, M. Rodrigues","doi":"10.52106/2766-3213.1015","DOIUrl":"https://doi.org/10.52106/2766-3213.1015","url":null,"abstract":"Sars-Cov 2 viral infection can cause an intense inflammatory reaction, hypoxemia and acute respiratory failure. The disease spreads more easily in chronic comorbidities, such as sickle cell anemia and overweight. Among the various professionals involved in the recovery of patients with Covid-19, the role of the physiotherapist stands out, not only for acting in the management of the disease but also for preventing and rehabilitating the respiratory deficiencies and the functional limitations caused by it. The present report aims to elucidate the multidisciplinary work carried out in the patient with overweight and sickle cell anemia during the period of hospitalization in the Pediatric Intensive Care Unit by Covid-19. This is an observational, longitudinal single-arm case report. The patient’s medical data collection was carried out retrospectively through record, including anamnesis reports, physical examination, and multi-professional procedures used from admission to discharge, including anamnesis reports, physical examination, and multi-professional procedures used from admission to discharge. The present study is a rare case of pediatric Covid-19 with severe signs and symptoms. The treatment performed by the multidisciplinary team resulted in a favorable outcome since the beginning of hospitalization. Physiotherapy, including early mobilization and rehabilitation may help prevent or mitigate sequelae related to bed rest, thus improving physical function and outcomes and reducing length of stay by increasing ventilator free-days.","PeriodicalId":375458,"journal":{"name":"MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129477132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrocephalus Revealed by Relapsing Bilateral Fourth Cranial Nerve Palsy 复发性双侧第四脑神经麻痹提示脑积水

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-12-30 DOI: 10.52106/2766-3213.1016

Loïc Moens, A. Boschi, T. Duprez, J. Ribeiro-Vaz

引用次数: 0

Practice Recommendations for the Physiotherapy in a Pediatric Intensive Care Unit: COVID-19 小儿重症监护病房物理治疗的实践建议:COVID-19

MEDICAL AND CLINICAL RESEARCH: OPEN ACCESS Pub Date : 2020-06-30 DOI: 10.52106/2766-3213.1004

C. G. Ribas, V. Neves, E. F. D. Souza, A. Koliski, J. Carreiro

引用次数: 1