A Study About Development of The Reticular Fibers Under the Nail in Human Embryos.

Y. Kishi, Naoshi Hashimoto
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Abstract

This study demonstrates the formation of reticular fibers under fetus nail during the nail development. The seventy-one digits of human fetus had been kept in the buzan stein in the department of the second Anatomy since 1970. They were amputated to measure the length and checked the shape. Then paraffin fixation method was performed. While the nail was formed, we observed using H-E stein and PAM stein how the reticular fibers under the nail were produced. In the early stage of nail formation, the basal layer of the epidermis was positive in PAM stein from matrix and nail bed. Under the basal layer the reticular fibers also were dyed like an arched bridge from the tip of distal phalanx before the matrix primordium was formed. Within the period after the matrix proximordium was produced, the reticular fibers developed under the nail bed especially at the two parts. One part is between the distal phalanx and the matrix primordium. The other is between the tip of distal phalanx and the distal groove. These fibers became thick gradually. In our study, the nail bed and matrix were constantly positive in PAM stein during nail formation. It shows that the nail bed and matrix make the reticular fibers during the nail developmental stage. The ridged connection between the tip of the nail and the distal phalanx is made by the reticular fibers.
人胚胎指甲下网状纤维发育的研究。
本研究证实了胎儿甲发育过程中甲下网状纤维的形成。1970年以来,人类胎儿的71根指骨一直保存在第二解剖科的藏宝箱中。他们被截肢来测量长度和检查形状。石蜡固定法。当钉形成时,我们使用H-E stein和PAM stein观察钉下网状纤维是如何产生的。甲形成初期,表皮基底层基质和甲床的PAM蛋白呈阳性。基底层下的网状纤维在基质原基形成前也从远端指骨尖端呈弓桥状染色。在近端基质形成后的一段时间内,甲床下的网状纤维开始发育,尤其是在甲床的两部分。一部分位于远端指骨和基质原基之间。另一个在远端指骨尖端与远端沟之间。这些纤维逐渐变粗了。在我们的研究中,甲床和基质在甲形成过程中持续呈阳性。说明甲床和甲基质在甲发育阶段形成网状纤维。甲尖和远端指骨之间的脊状连接是由网状纤维形成的。
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