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Evidence of chikungunya virus infection among febrile patients seeking healthcare in selected districts of Tanzania. 坦桑尼亚部分地区发热病人就医时感染基孔肯雅病毒的证据。
Infection Ecology and Epidemiology Pub Date : 2018-12-17 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1553460
Edson Kinimi, Mariana J Shayo, Bisimwa N Patrick, Samuel O Angwenyi, Christopher J Kasanga, Jacqueline Weyer, Petrus Jansen van Vuren, Janusz T Paweska, Leonard E G Mboera, Gerald Misinzo
{"title":"Evidence of chikungunya virus infection among febrile patients seeking healthcare in selected districts of Tanzania.","authors":"Edson Kinimi, Mariana J Shayo, Bisimwa N Patrick, Samuel O Angwenyi, Christopher J Kasanga, Jacqueline Weyer, Petrus Jansen van Vuren, Janusz T Paweska, Leonard E G Mboera, Gerald Misinzo","doi":"10.1080/20008686.2018.1553460","DOIUrl":"10.1080/20008686.2018.1553460","url":null,"abstract":"<p><p><b>Introduction</b>: Chikungunya virus (CHIKV) infection is an emerging mosquito-borne disease that has been associated with frequent epidemics in the world. However, there is a dearth of information on its magnitude and associated risk factors in Tanzania. <b>Objective</b>: A study was conducted to determine seroprevalence of CHIKV among febrile patients seeking medical care at health facilities in Karagwe, Sengerema, Kilombero and Kyela districts. <b>Methods</b>: Structured questionnaires were administered and 728 serum samples were collected between May and June, 2015 and tested for the presence of CHIKV-IgM and IgG-specific antibodies using Enzyme-linked immunosorbent assay. <b>Results and discussion</b>: The common clinical characteristics exhibited by outpatients were fever, headache and joint pains (100%, 70%, and 68.3% respectively). Out of 728 outpatients screened for CHIKV, 105 (14%) tested CHIKV IgG positive whilst 11 (1.5%) tested CHIKV IgM positive. Chikungunya seropositivity was significantly higher than previously reported in Tanzania. The most affected age group was 20-29 years. Our results indicate that CHIKV infection is prevalent and contributes to the burden of febrile illnesses in Tanzania. The seroprevalence varies between districts, reflecting variation in mosquito vector transmission dynamics in different parts of the country. <b>Abbreviations:</b> CHIKV: Chikungunya virus; EDTA: Ethylenediaminetetraacetic acid; ELISA: Enzyme-linked immunosorbent assay; IgG: Immunoglobulin G; IgM: Immunoglobulin M; NIMR: National Institute for Medical Research; RU: Relative Units; SACIDS: Southern African Centre for Infectious Disease Surveillance; USA: United States of America.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1553460"},"PeriodicalIF":0.0,"publicationDate":"2018-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37025040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The enzyme toilet rim block 'pCure' does not efficiently remove drug residues in a hospital setting - exemplifying the importance of on-site implementation testing. 酶马桶圈块“pure”不能有效地去除医院环境中的药物残留,这说明了现场实施测试的重要性。
Infection Ecology and Epidemiology Pub Date : 2018-12-06 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1553463
Sofia Svebrant, Therese Olsen, Jim Larsson, Patrik Öhagen, Hanna Söderström, Josef D Järhult
{"title":"The enzyme toilet rim block 'pCure' does not efficiently remove drug residues in a hospital setting - exemplifying the importance of on-site implementation testing.","authors":"Sofia Svebrant,&nbsp;Therese Olsen,&nbsp;Jim Larsson,&nbsp;Patrik Öhagen,&nbsp;Hanna Söderström,&nbsp;Josef D Järhult","doi":"10.1080/20008686.2018.1553463","DOIUrl":"https://doi.org/10.1080/20008686.2018.1553463","url":null,"abstract":"<p><p><b>Introduction:</b> Negative environmental effects of active pharmaceutical ingredients (APIs) are increasingly recognized, especially concerning antibiotics, and hospitals are important point sources. \"pCure\" is a toilet rim block containing API-degrading enzymes; the producing company claims positive in vitro results but no implementation studies have been performed. <b>Materials and methods:</b> In a university hospital setting, 16 weeks were randomized to installation or no installation of pCure in all 261 toilets connected to the same cesspit where sewage water was sampled daily. Ninety-six samples were analyzed for 102 APIs using liquid chromatography/tandem mass spectrometry. <b>Results and Discussion:</b> Fifty-one APIs were detected with a large variation in levels but no significant differences in the initial statistical analysis. More statistical testing of API level ratios (pCure installed/not installed) yielded some cases of significant decrease. Differences were small and not consistent when comparing means and medians. We cannot exclude a small pCure effect but clearly pCure has no effect of biological importance. <b>Conclusion:</b> pCure is not useful to reduce drug residue discharge in a hospital setting. In a bigger perspective, our study exemplifies that products claiming to reduce an environmental problem need to be tested in on-site implementation studies by independent researchers before reaching the market.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1553463"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1553463","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37035861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assessing the impact of bacteriophages in the treatment of Salmonella in broiler chickens. 评估噬菌体对肉鸡沙门氏菌治疗的影响。
Infection Ecology and Epidemiology Pub Date : 2018-10-30 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1539056
Nehal M Nabil, Maram M Tawakol, Heba M Hassan
{"title":"Assessing the impact of bacteriophages in the treatment of Salmonella in broiler chickens.","authors":"Nehal M Nabil,&nbsp;Maram M Tawakol,&nbsp;Heba M Hassan","doi":"10.1080/20008686.2018.1539056","DOIUrl":"https://doi.org/10.1080/20008686.2018.1539056","url":null,"abstract":"<p><p>Salmonellosis is one of the main bacterial infections affecting commercial poultry, causing losses to poultry production, and posing a public health concern. Samples from internal organs (liver, cecum and spleen) of one hundred diseased broiler chickens were collected and subjected to <i>Salmonella</i> isolation, identification and serotyping. <i>S. typhimurium</i> and <i>S. enteritidis</i> were selected from the isolated <i>Salmonella</i> to prepare bacteriophages from sewage water taken at broiler farms. An experimental infection of one day old specific pathogen free (SPF) chicks followed by treatment with the prepared bacteriophages isolated from both <i>Salmonella</i> was performed. Caecal samples from infected chicks were subjected at intervals to bacteriophage isolation and <i>Salmonella</i> quantitation. The effectiveness of bacteriophage treatments on <i>Salmonella</i> colonization in cecum of infected chicks increased after five successive doses. At 3 day post infection (dpi), cecal contents showed a marginal decrease in Salmonella loads with more reduction at 5 dpi. From 7 dpi to the end of the experiment at 15 dpi, all the chicks were cleared for both <i>Salmonella</i>. The findings of this study demonstrate that bacteriophage treatment is efficacious in reducing <i>S. typhimurium</i> and <i>S. enteritidis</i> colonization in broiler chickens within a short period and could be used as an alternative to antibiotics.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1539056"},"PeriodicalIF":0.0,"publicationDate":"2018-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1539056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36638850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Baseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by the in silico approach. 基因型1、2和3的丙型肝炎病毒基线达沙布韦耐药及ns5b -达沙布韦复合物的计算机模拟
Infection Ecology and Epidemiology Pub Date : 2018-10-05 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1528117
Dario Akaberi, Assar Bergfors, Midori Kjellin, Nader Kameli, Louise Lidemalm, Bhavya Kolli, Robert W Shafer, Navaneethan Palanisamy, Johan Lennerstrand
{"title":"Baseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by the <i>in silico</i> approach.","authors":"Dario Akaberi,&nbsp;Assar Bergfors,&nbsp;Midori Kjellin,&nbsp;Nader Kameli,&nbsp;Louise Lidemalm,&nbsp;Bhavya Kolli,&nbsp;Robert W Shafer,&nbsp;Navaneethan Palanisamy,&nbsp;Johan Lennerstrand","doi":"10.1080/20008686.2018.1528117","DOIUrl":"https://doi.org/10.1080/20008686.2018.1528117","url":null,"abstract":"<p><p><b>Background:</b> Current combination treatments with direct-acting antiviral agents (DAAs) can cure more than 95% of hepatitis C virus (HCV) infections. However, resistance-associated substitutions (RASs) may emerge and can also be present in treatment-naïve patients. <b>Methods, results and discussion:</b> In this study, a semi-pan-genotypic population sequencing method was developed and used to assess all NS5B amino acid variants between residue positions 310 and 564. Our method successfully sequenced more than 90% of genotype (GT) 1a, 1b, 2b and 3a samples. By using the population sequencing method with a cut-off of 20%, we found the dasabuvir RASs A553V and C445F to be a baseline polymorphism of GT 2b (8 out of 8) and GT 3a (18 out of 18) sequences, respectively. In GT 1a and 1b treatment-naïve subjects (n=25), no high-fold resistance polymorphism/RASs were identified. We further predicted dasabuvir's binding pose with the NS5B polymerase using the <i>in silico</i> methods to elucidate the reasons associated with the resistance of clinically relevant RASs. Dasabuvir was docked at the palm-I site and was found to form hydrogen bonds with the residues S288, I447, Y448, N291 and D318. The RAS positions 316, 414, 448, 553 and 556 were found to constitute the dasabuvir binding pocket.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1528117"},"PeriodicalIF":0.0,"publicationDate":"2018-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1528117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36584841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia. 南乔治亚亚南极岛野生驯鹿(Rangifer t. tarandus)和海带鸥(Larus dominicanus)中罗氏耶尔森氏菌的出现。
Infection Ecology and Epidemiology Pub Date : 2018-09-11 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1517582
Jonas Bonnedahl, Charlotte Berg, Dan I Andersson, Robert Söderlund, Ivar Vågsholm, Björn Olsen
{"title":"Occurrence of <i>Yersinia rohdei</i> among feral reindeer (<i>Rangifer t. tarandus</i>) and kelp gulls (<i>Larus dominicanus</i>) on the Sub-Antarctic island South Georgia.","authors":"Jonas Bonnedahl,&nbsp;Charlotte Berg,&nbsp;Dan I Andersson,&nbsp;Robert Söderlund,&nbsp;Ivar Vågsholm,&nbsp;Björn Olsen","doi":"10.1080/20008686.2018.1517582","DOIUrl":"https://doi.org/10.1080/20008686.2018.1517582","url":null,"abstract":"<p><p><b>Introduction:</b> During a research expedition in 2012, faecal samples were collected from feral reindeer and kelp gulls on the main island of South Georgia in the Sub-Antarctic region of the Atlantic. The samples were analysed for bacteria of the genus Yersinia with the aim of identifying isolates to the species level. <b>Materials and Methods:</b> A total of 11 reindeer samples and 26 Kelp Gull samples were retrieved from the location of Stromness, kept refrigerated and cultivated for gram-negative bacteria. <b>Results:</b> Three of the samples showed growth of Yersinia rohdei, as confirmed by biochemical typing, MALDI-TOF and 16S rRNA sequencing. The isolates were indistinguishable from each other by 16S sequencing, and differed by a single base pair from the type strain of Y. rohdei. <b>Discussion:</b> The Yersinia genus contains well-known pathogens of significance to both human and veterinary medicine, but the public health and animal health relevance of Y. rohdei is unknown. Although it is clear that Y. rhodei is present in the south Georgian biotope, its importance and relevance for biological diversity is unknown, as is if this presence is merely a reflection of human activities.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1517582"},"PeriodicalIF":0.0,"publicationDate":"2018-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1517582","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37417937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prevalence of Leptospira spp. and Seoul hantavirus in brown rats (Rattus norvegicus) in four regions in the Netherlands, 2011-2015. 2011-2015年荷兰四个地区褐鼠(褐家鼠)钩端螺旋体属和首尔汉坦病毒的流行情况。
Infection Ecology and Epidemiology Pub Date : 2018-06-26 DOI: 10.1080/20008686.2018.1490135
Miriam Maas, Ankje De Vries, Chantal Reusken, Jan Buijs, Marga Goris, Rudy Hartskeerl, Ahmed Ahmed, Peter Van Tulden, Arno Swart, Roan Pijnacker, Miriam Koene, Åke Lundkvist, Paul Heyman, Barry Rockx, Joke Van Der Giessen
{"title":"Prevalence of <i>Leptospira</i> spp. and Seoul hantavirus in brown rats (<i>Rattus norvegicus</i>) in four regions in the Netherlands, 2011-2015.","authors":"Miriam Maas,&nbsp;Ankje De Vries,&nbsp;Chantal Reusken,&nbsp;Jan Buijs,&nbsp;Marga Goris,&nbsp;Rudy Hartskeerl,&nbsp;Ahmed Ahmed,&nbsp;Peter Van Tulden,&nbsp;Arno Swart,&nbsp;Roan Pijnacker,&nbsp;Miriam Koene,&nbsp;Åke Lundkvist,&nbsp;Paul Heyman,&nbsp;Barry Rockx,&nbsp;Joke Van Der Giessen","doi":"10.1080/20008686.2018.1490135","DOIUrl":"10.1080/20008686.2018.1490135","url":null,"abstract":"<p><strong>Background: </strong>  Brown rats (<i>Rattus norvegicus</i>) may carry pathogens that can be a risk for public health. Brown rats in the Netherlands were tested for the zoonotic pathogens <i>Leptospira</i> spp. and Seoul hantavirus (SEOV), in order to obtain insight in their prevalence.</p><p><strong>Methods and results: </strong>  Cross-sectional studies were performed at four locations from 2011 to 2015. The rats were tested for <i>Leptospira</i> spp. using real-time PCR and/or culture resulting in a prevalence ranging between 33-57%. Testing for SEOV was done through an adapted human Seoul hantavirus ELISA and real-time RT-PCR. Although at several locations the ELISA indicated presence of SEOV antibodies, none could be confirmed by focus reduction neutralization testing.</p><p><strong>Conclusion: </strong>  The results indicate a widespread presence of <i>Leptospira</i> spp. in brown rats in the Netherlands, including areas with a low leptospirosis incidence in humans. No evidence for circulation of SEOV was found in this study.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1490135"},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1490135","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36275872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Viral metagenomics reveals the presence of highly divergent quaranjavirus in Rhipicephalus ticks from Mozambique. 病毒宏基因组学显示在莫桑比克鼻头蜱中存在高度分化的夸兰病毒。
Infection Ecology and Epidemiology Pub Date : 2018-05-28 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1478585
Harindranath Cholleti, Juliette Hayer, Fernando Chanisso Mulandane, Kerstin Falk, Jose Fafetine, Mikael Berg, Anne-Lie Blomström
{"title":"Viral metagenomics reveals the presence of highly divergent quaranjavirus in <i>Rhipicephalus</i> ticks from Mozambique.","authors":"Harindranath Cholleti,&nbsp;Juliette Hayer,&nbsp;Fernando Chanisso Mulandane,&nbsp;Kerstin Falk,&nbsp;Jose Fafetine,&nbsp;Mikael Berg,&nbsp;Anne-Lie Blomström","doi":"10.1080/20008686.2018.1478585","DOIUrl":"https://doi.org/10.1080/20008686.2018.1478585","url":null,"abstract":"<p><p><b>Background:</b> Ticks are primary vectors for many well-known disease-causing agents that affect human and animal populations globally such as tick-borne encephalitis, Crimean-Congo hemorrhagic fever and African swine fever. In this study, viral metagenomics was used to identify what viruses are present in <i>Rhipicephalus</i> spp. ticks collected in the Zambezi Valley of Mozambique. <b>Methods:</b> The RNA was amplified with sequence-independent single primer amplification (SISPA) and high-throughput sequencing was performed on the Ion Torrent platform. The generated sequences were subjected to quality check and classfied by BLAST. CodonCode aligner and SeqMan were used to assemble the sequences. <b>Results:</b> The majority of viral sequences showed closest sequence identity to the <i>Orthomyxoviridae</i> family, although viruses similar to the <i>Parvoviridae</i> and <i>Coronaviridae</i> were also identified. Nearly complete sequences of five orthomyxoviral segments (HA, NP, PB1, PB2, and PA) were obtained and these showed an amino acid identity of 32-52% to known quaranjaviruses. The sequences were most closely related to the Wellfleet Bay virus, detected and isolated from common eider during a mortality event in the USA. <b>Conclusions:</b> In summary, this study has identified a highly divergent virus with in the <i>Orthomyxoviridae</i> family associated with <i>Rhipicephalus</i> ticks from Mozambique. Further genetic and biological studies are needed in order to investigate potential pathogenesis of the identified orthomyxovirus.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1478585"},"PeriodicalIF":0.0,"publicationDate":"2018-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1478585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36192439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Detection of Influenza A viruses at migratory bird stopover sites in Michigan, USA. 在美国密西根州候鸟停留地点检测甲型流感病毒。
Infection Ecology and Epidemiology Pub Date : 2018-05-18 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1474709
Todd M Lickfett, Erica Clark, Thomas M Gehring, Elizabeth W Alm
{"title":"Detection of Influenza A viruses at migratory bird stopover sites in Michigan, USA.","authors":"Todd M Lickfett,&nbsp;Erica Clark,&nbsp;Thomas M Gehring,&nbsp;Elizabeth W Alm","doi":"10.1080/20008686.2018.1474709","DOIUrl":"https://doi.org/10.1080/20008686.2018.1474709","url":null,"abstract":"<p><p><b>Introduction:</b> Influenza A viruses have the potential to cause devastating illness in humans and domestic poultry. Wild birds are the natural reservoirs of Influenza A viruses and migratory birds are implicated in their global dissemination. High concentrations of this virus are excreted in the faeces of infected birds and faecal contamination of shared aquatic habitats can lead to indirect transmission among birds via the faecal-oral route. The role of migratory birds in the spread of avian influenza has led to large-scale surveillance efforts of circulating avian influenza viruses through direct sampling of live and dead wild birds. Environmental monitoring of bird habitats using molecular detection methods may provide additional information on the persistence of influenza virus at migratory stopover sites distributed across large spatial scales. <b>Materials and methods:</b> In the current study, faecal and water samples were collected at migratory stopover sites and evaluated for Influenza A by real-time quantitative reverse transcriptase PCR. <b>Results and Discussion:</b> This study found that Influenza A was detected at 53% of the evaluated stopover sites, and 7% and 4.8% of the faecal and water samples, respectively, tested positive for Influenza A virus. <b>Conclusion:</b> Environmental monitoring detected Influenza A at stopover sites used by migratory birds.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1474709"},"PeriodicalIF":0.0,"publicationDate":"2018-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1474709","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36135405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
A longitudinal ecological study of seasonal influenza deaths in relation to climate conditions in the United States from 1999 through 2011. 1999年至2011年美国季节性流感死亡与气候条件的纵向生态学研究
Infection Ecology and Epidemiology Pub Date : 2018-05-16 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1474708
David A Geier, Janet K Kern, Mark R Geier
{"title":"A longitudinal ecological study of seasonal influenza deaths in relation to climate conditions in the United States from 1999 through 2011.","authors":"David A Geier,&nbsp;Janet K Kern,&nbsp;Mark R Geier","doi":"10.1080/20008686.2018.1474708","DOIUrl":"https://doi.org/10.1080/20008686.2018.1474708","url":null,"abstract":"<p><p><b>Introduction:</b> Influenza is an acute respiratory disease with significant annual global morbidity/mortality. Influenza transmission occurs in distinct seasonal patterns suggesting an importance of climate conditions on disease pathogenesis. This hypothesis-testing study evaluated microenvironment conditions within different demographic/geographical groups on seasonal influenza deaths in the United States. <b>Materials and methods:</b>The United States Centers for Disease Control and Prevention (CDC) Wonder online computer interface was utilized to integrate and analyze potential correlations in data generated from 1999 through 2011 for climate conditions of mean daily sunlight (KJ/m<sup>2</sup>), mean daily maximum air temperature (<sup>o</sup>C), mean daily minimum air temperature (<sup>o</sup>C), and mean daily precipitation (mm) from the North America Land Data Assimilation System (NLDAS) database and on influenza mortality (ICD-10 codes:J09, J10, or J11) from the Underlying Cause of Death database. <b>Results and discussion:</b>Significant inverse correlations between the climate conditions of temperature, sunlight, and precipitation and seasonal influenza death rate were observed. Similar effects were observed among males and females, but when the data were separated by race and urbanization status significant differences were observed. <b>Conclusion:</b> This study highlights key factors that can help shape public health policy to deal with seasonal influenza in the United States and beyond.</p>","PeriodicalId":37446,"journal":{"name":"Infection Ecology and Epidemiology","volume":" ","pages":"1474708"},"PeriodicalIF":0.0,"publicationDate":"2018-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20008686.2018.1474708","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36135404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Seroprevalence of hantaviruses and Leptospira in muskrat and coypu trappers in the Netherlands, 2016. 2016年荷兰麝鼠和河狸鼠捕鼠者汉坦病毒和钩端螺旋体血清阳性率
Infection Ecology and Epidemiology Pub Date : 2018-05-16 eCollection Date: 2018-01-01 DOI: 10.1080/20008686.2018.1474707
Ingrid H M Friesema, Jacinta Bakker, Miriam Maas, Marga G A Goris, Joke W B van der Giessen, Barry H G Rockx
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引用次数: 4
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