Annals of Medicine & Surgery最新文献_第6页

Anisodamine for the prevention of contrast-induced nephropathy in patients with acute coronary syndrome: a pilot systematic review and meta-analysis of randomized controlled trials 用于预防急性冠状动脉综合征患者造影剂诱发肾病的茴香胺：随机对照试验的试验性系统回顾和荟萃分析

Annals of Medicine & Surgery Pub Date : 2024-05-21 DOI: 10.1097/ms9.0000000000002181

Hritvik Jain, Ramez M. Odat, Jyoti Jain, Debankur Dey, Ayham Mohammad Hussein, M. D. Marsool, Haania Shahbaz, Aniket Mathur, Himani Yadav, Siddhant Passey, Rukesh Yadav

{"title":"Anisodamine for the prevention of contrast-induced nephropathy in patients with acute coronary syndrome: a pilot systematic review and meta-analysis of randomized controlled trials","authors":"Hritvik Jain, Ramez M. Odat, Jyoti Jain, Debankur Dey, Ayham Mohammad Hussein, M. D. Marsool, Haania Shahbaz, Aniket Mathur, Himani Yadav, Siddhant Passey, Rukesh Yadav","doi":"10.1097/ms9.0000000000002181","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002181","url":null,"abstract":"\u0000 \u0000 Contrast-induced nephropathy (CIN) is a common post-procedural complication of percutaneous coronary intervention for acute myocardial infarction (AMI). Anisodamine hydrobromide is an alkaloid that has demonstrated efficacy in improving microcirculation. This meta-analysis aims to evaluate the reno-protective effects of Anisodamine in patients undergoing percutaneous coronary intervention (PCI) for AMI.\u0000 \u0000 \u0000 \u0000 PubMed, Embase, Cochrane Library, Scopus, and clinicaltrials.gov were searched from inception to January 2024 for randomized controlled trials (RCTs) comparing the efficacy of Anisodamine in preventing the development of CIN. Outcomes of interest included the incidence of CIN, serum creatinine levels, and estimated glomerular filtration rate (eGFR). A random-effects model was used for pooling standard mean differences (SMDs) and odds ratios (ORs) with a 95% confidence interval (CI). Statistical significance was considered at a P<0.05.\u0000 \u0000 \u0000 \u0000 3 RCTs involving 563 patients were included. Anisodamine was associated with a reduction in the incidence of CIN [OR: 0.44; 95% CI: 0.28, 0.69; P=0.0003], a reduction in serum creatinine levels at 48 [SMD: −6.78; 95% CI: −10.54,−3.02; P=0.0004] and 72 hours [SMD: −6.74; 95% CI: −13.33,−0.15; P=0.03], and a higher eGFR at 24 [SMD: 5.77; 95% CI: 0.39, 11.14; P=0.03], and 48 hours [SMD: 4.70; 95% CI: 2.03,7.38; P=0.0006]. The levels of serum creatinine at 24 hours and eGFR value at 72 hours were comparable between both groups.\u0000 \u0000 \u0000 \u0000 Anisodamine has demonstrated clinical efficacy in ameliorating the development of CIN post-PCI in AMI patients. Large, multi-centric RCTs are warranted to evaluate the robustness of these findings.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"70 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual initiation of an ocular form of musk-positive myasthenia gravis after magnesium administration: A rare case report 麝香阳性重症肌无力患者在服用镁后出现眼部症状的罕见病例：罕见病例报告

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002193

Ahmad Almohamed, S. Karaja, Ayham Qatza, Mais Halloum, Ghina hamsho, Wisal Katmeh, Waddah Kazkz

{"title":"An unusual initiation of an ocular form of musk-positive myasthenia gravis after magnesium administration: A rare case report","authors":"Ahmad Almohamed, S. Karaja, Ayham Qatza, Mais Halloum, Ghina hamsho, Wisal Katmeh, Waddah Kazkz","doi":"10.1097/ms9.0000000000002193","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002193","url":null,"abstract":"\u0000 \u0000 The primary clinical symptom in people with myasthenia gravis is muscle weakness that gets worse with activity and gets better with rest; often, the first symptoms are ocular ones, such as ptosis and double vision. On the other hand, individuals with anti-MuSK may present with unusual symptoms. Nonetheless, it is hypothesized that musk antibodies may be present when there are no antibodies present along with bulbar and respiratory symptoms.\u0000 \u0000 \u0000 \u0000 A 26-year-old pregnant patient was referred to the neurology department after experiencing tongue enlargement. A neuro ophthalmic assessment revealed ptosis with lateral diplopia in the right eye, bulbar palsy, facial weakness, weakness in the palate and pharyngeal reflex, dizziness, and hearing loss in her right ear. The patient was given magnesium sulfate for two days since pre-eclampsia was suspected; however, this treatment exacerbated the development of symptoms and was discontinued. Her myasthenia gravis symptoms gradually improved after starting medication nonetheless, bilateral weakness in the neck and limb flexion persisted. Following a few days of therapy, there were no indications of diplopia, swallowing was normal, and the muscular weakness was somewhat improved.\u0000 \u0000 \u0000 \u0000 The pasiont put on drug treatment for myasthenia gravis (predlon 60 mg daily, amioran 50 mg twice daily and mistenon)\u0000 \u0000 \u0000 \u0000 Treating severe myasthenia gravis patients with a customized approach aims to manage their symptoms and improve their quality of life. Reduce muscle weakness, eradicate circulating antibodies, and suppress the abnormal immunological response. Minimizing side effects while attaining ideal symptom control is the ultimate objective.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"32 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141118900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed infected hematoma in retrosternal area following total thyroidectomy: a case report 甲状腺全切除术后胸骨后延迟感染性血肿：病例报告

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002177

Hao Zhao, Xi-yuan Chen, Jing Wang, Tian-Xiong Li, Pu-Xi-Dan Huang, De-Xiao Du, Bu-He A-Min

{"title":"Delayed infected hematoma in retrosternal area following total thyroidectomy: a case report","authors":"Hao Zhao, Xi-yuan Chen, Jing Wang, Tian-Xiong Li, Pu-Xi-Dan Huang, De-Xiao Du, Bu-He A-Min","doi":"10.1097/ms9.0000000000002177","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002177","url":null,"abstract":"\u0000 \u0000 Postoperative neck hematoma (PNH), a rare complication following thyroidectomy, occurs in only 1.1%-3.15% of cases and can lead to life-threatening outcomes. More rarely, delayed PNHs with atypical clinical manifestations and positions have not yet been reported. Early identification and immediate medical intervention are of utmost importance in such cases.\u0000 \u0000 \u0000 \u0000 The authors represented a patient with thyroid cancer adherent to the trachea, who underwent post-thyroidectomy, experienced delayed PNH in the retrosternal region and was infected by respiratory pathogens. Meanwhile, the patient developed recurrent laryngeal nerve (RLN) paralysis after surgery. PNH was not identified in the clinical manifestations; instead, it was detected only through successive cervical ultrasound examinations.\u0000 \u0000 \u0000 \u0000 Although rare, PNH can lead to serious complications, especially delayed complications or those in atypical positions, without neck swelling. When simultaneously with RLN paralysis, the hematoma may be neglected. Therefore, early diagnosis and treatment are crucial.\u0000 \u0000 \u0000 \u0000 Clinicians should be vigilant of atypical PNH because neck swelling may be absent. Cervical ultrasonography is essential for diagnosis and can be performed multiple times. Cervical CT scans should be part of the routine procedure, while contrast-enhanced ultrasound can help detect active bleeding. Early postoperative antibiotics are recommended if the tumor is closely attached to the trachea.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"68 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141121440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute non peurperal uterine inversion caused by leiomyma associated with precancerous lesions: A case report 由伴有癌前病变的子宫白膜引起的急性非月经期子宫内翻：病例报告

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002166

H. Barghash, Dania Basaleh, Haya Shahada, Maya Abbas, Hiba Al Ali, Haitham Abbassi

{"title":"Acute non peurperal uterine inversion caused by leiomyma associated with precancerous lesions: A case report","authors":"H. Barghash, Dania Basaleh, Haya Shahada, Maya Abbas, Hiba Al Ali, Haitham Abbassi","doi":"10.1097/ms9.0000000000002166","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002166","url":null,"abstract":"\u0000 \u0000 Acute non-puerperal uterine inversion (Acute NPUI) is a rare clinical entity that is usually associated with a polypoid uterine tumor, usually a leiomyoma, but its occurrence due to combined leiomyoma with precancerous lesions is quite exceptional.\u0000 \u0000 \u0000 \u0000 Here, the authors present the case of a 65-year-old woman who was diagnosed with acute NPUI as an unusual complication of prolapsed fibroid.\u0000 \u0000 \u0000 \u0000 On abdominal examination, palpation of the lower abdomen was very painful. On pelvic examination, a huge hemorrhagic mass was noticed, with necrotic areas protruding at a level 10 cm above the introitus. The cervix could not be palpated or visualized, and the uterus was difficult to appreciate on a bimanual examination due to tenderness. By transabdominal sonography, the uterus could not be clearly identified. Routine blood tests were completely normal, including hemoglobin concentrations. First of all, we manually replaced the inverted uterus in its normal position and then performed a total hysterectomy and a bilateral adnexectomy. Pathological findings demonstrated a leiomyoma with areas of complex hyperplasia with atypia!\u0000 \u0000 \u0000 \u0000 When we encounter a case of non-puerperal uterine inversion, we must consider fibroids as the most common cause, and we must act quickly so that the patient does not go into neurogenic shock and die. Although leiomyoma is the most common cause of NPUI, a pathological study should be performed in all cases.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141120623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spleen autotransplantation on liver vs. greater omentum for simultaneous injuries of liver and spleen: An experimental study 肝脏与大网膜脾脏自体移植治疗肝脾同时损伤：一项实验研究

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002198

Mohammad Eslamian, Erfan Sheikhbahaei, Behnam Sanei, Alireza Rahmati, M. Moslehi, Hamidreza Zefreh, Arshin Ghaedi, Alireza Firouzfar

{"title":"Spleen autotransplantation on liver vs. greater omentum for simultaneous injuries of liver and spleen: An experimental study","authors":"Mohammad Eslamian, Erfan Sheikhbahaei, Behnam Sanei, Alireza Rahmati, M. Moslehi, Hamidreza Zefreh, Arshin Ghaedi, Alireza Firouzfar","doi":"10.1097/ms9.0000000000002198","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002198","url":null,"abstract":"\u0000 \u0000 In a simulated situation of simultaneous spleen and liver trauma, we aimed to compare the outcomes of treating both injuries with spleen autotransplantation on the omentum alongside hepatorrhaphy vs. spleen autotransplantation as a patch on the liver parenchyma.\u0000 \u0000 \u0000 \u0000 A total of 24 rats were separated into two groups: the spleen autotransplantation on the omentum (SAO) and the liver (SAL). They underwent a uniform and simultaneous procedure involving full-thickness injuries to the left lobe of the liver and grade-four spleen injuries. We measured hemoglobin (Hb), white blood cell (WBC), complement (C3 and C4), and immunoglobulin G, M, and A (IgG, IgM, IgA) levels before and four weeks after the surgery. We utilized Technetium-99m scintigraphy to evaluate the post-transplant splenic graft functions four weeks after the surgery.\u0000 \u0000 \u0000 \u0000 The two groups had no significant difference in the hematologic and immunologic factors before surgery. However, both procedures significantly reduced Hb, C3, IgG, and IgA levels (all P<0.05). WBC counts significantly increased in the SAO group, whereas the IgM level decreased after the intervention (P<0.05). WBC was increased in the SAO group, while IgM and IgA were decreased in the SAO group. The Technetium uptake was similar between the two groups (P=0.3).\u0000 \u0000 \u0000 \u0000 In simultaneous spleen and liver injuries, the autotransplantation of splenic into the liver parenchyma appears to be a promising surgical approach for preserving spleen function and hepatorrhaphy at the same time instead of doing them separately.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"34 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141118778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transforming the management of chronic kidney disease-associated anemia using daprodustat 使用达泊司他：改变慢性肾病相关贫血的治疗方法

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002207

Ifrah Inbisat Raza, Shaheera Younus, Hiba Azhar, Hareer Fatima, Zainab Anwar, A. A. Farah, Hussain Sohail Rangwala

引用次数: 0

Gastric carcinoma of the fundic gland type developed 32 years after Helicobacter pylori eradication for duodenal ulcer: a case report 根除幽门螺杆菌治疗十二指肠溃疡 32 年后发生的胃底腺癌：病例报告

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002192

Daisuke Suto, Kiichi Sato, Masashi Yoshida, Hiroyoshi Ota, T. Otake, Yosuke Osawa, Yoshimasa Nakazato, H. Ohdaira, Yutaka Suzuki, Yutaka Kohgo

{"title":"Gastric carcinoma of the fundic gland type developed 32 years after Helicobacter pylori eradication for duodenal ulcer: a case report","authors":"Daisuke Suto, Kiichi Sato, Masashi Yoshida, Hiroyoshi Ota, T. Otake, Yosuke Osawa, Yoshimasa Nakazato, H. Ohdaira, Yutaka Suzuki, Yutaka Kohgo","doi":"10.1097/ms9.0000000000002192","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002192","url":null,"abstract":"\u0000 \u0000 Gastric cancer has been reported to occur with mild to moderate mucosal atrophy, particularly after the eradication of Helicobacter pylori (HP) more than 10 years previously. However, no conclusion has been reached on how many years of esophagogastroduodenoscopy should be performed after HP eradication.\u0000 \u0000 \u0000 \u0000 This was a case of gastric carcinoma of the fundic gland type (GCFGT) 32 years after the eradication of HP, which is the longest post-eradication period reported. A 62-year-old male patient was diagnosed with GCFGT after HP eradication and regular esophagogastroduodenoscopy, which revealed a white raised lesion on the anterior wall of the upper part of the body. Endoscopic submucosal dissection was performed for GCFGT, and the vertical and horizontal margins were negative.\u0000 \u0000 \u0000 \u0000 In this case, HP was eradicated in 1990, and GCFGT developed 32 years later. To the best of our knowledge, this is the longest case in which gastric cancer appeared after HP eradication. HP eradication therapy for a duodenal ulcer was first reported in 1990, supporting that this is the longest case.\u0000 \u0000 \u0000 \u0000 This is the first case of gastric cancer more than 20 years after the eradication of HP. The endoscopic findings of this case are typical of GCFGT and may be useful when encountering such cases in the future. Therefore, the risk of gastric cancer should be considered for an extended period even after the eradication of HP, and regular esophagogastroduodenoscopy is recommended even after the eradication of HP.\u0000","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"19 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141120105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new Era in meningitis prevention: implications of Nigeria’s 5-in-1 vaccine rollout 脑膜炎预防的新时代：尼日利亚推广五合一疫苗的意义

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002199

Ayush Anand, Amogh Verma, N. Woldehana, Prakasini Satapathy, Rakesh Kumar Sharma, Divya Sharma, Mithhil Arora, M. Khatib, Shilpa Gaidhane, Q. Zahiruddin, Sarvesh Rustagi

引用次数: 0

Leniolisib: A drug providing a promising avenue for the treatment of activated phosphoinositide 3-kinase δ syndrome (APDS) 莱尼利西布为治疗活化磷酸肌酸 3-激酶δ综合征（APDS）提供前景广阔的药物

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002189

Anoshia Ali, Amsal Qureshi, Anum Fatima Shigri, A. Alvi, Abdullah Malikzai

引用次数: 0

Adverse events associated with chimeric antigen receptor T-Cell therapy in ophthalmology: a narrative review 与眼科嵌合抗原受体 T 细胞疗法相关的不良事件：叙述性综述

Annals of Medicine & Surgery Pub Date : 2024-05-20 DOI: 10.1097/ms9.0000000000002188

Sara Sarwar, Unood Riaz, Abraish Ali, Sejal Jain Kailash

{"title":"Adverse events associated with chimeric antigen receptor T-Cell therapy in ophthalmology: a narrative review","authors":"Sara Sarwar, Unood Riaz, Abraish Ali, Sejal Jain Kailash","doi":"10.1097/ms9.0000000000002188","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002188","url":null,"abstract":"Chimeric antigen receptors are synthetically produced receptors engineered to engage with target cells with high specificity. These cells are created by inserting an artificial T-cell receptor into an immunoglobulin’s antigen-binding region, allowing the cells to combine and target specific antigens. The use of chimeric antigen receptor (CAR) T-cell therapy has been a remarkable achievement in the field of immunotherapy, particularly in the treatment of ophthalmic tumors like retinoblastoma and uveal melanoma. However, there are some documented side effects, such as cytokine release syndrome (CRS) and immunological effector cell-associated neurotoxicity syndrome (ICANS). Additionally, ocular side effects such as blurred vision, vision impairment, and intraocular infections are also concerning and require further evaluation. This review highlights the advances made in chimeric antigen receptor (CAR) immunotherapy, including its structure and manufacture, as well as relevant clinical discoveries and associated adverse effects. By identifying the gaps in current research, this analysis provides insights into potential strategies and solutions for addressing some of the most severe side effects.","PeriodicalId":373451,"journal":{"name":"Annals of Medicine & Surgery","volume":"29 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141120593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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Annals of Medicine & Surgery最新文献