Journal of Imaging最新文献

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MediScan: A Framework of U-Health and Prognostic AI Assessment on Medical Imaging. meddiscan: u -健康和医学成像预后人工智能评估框架。
IF 2.7
Journal of Imaging Pub Date : 2024-12-13 DOI: 10.3390/jimaging10120322
Sibtain Syed, Rehan Ahmed, Arshad Iqbal, Naveed Ahmad, Mohammed Ali Alshara
{"title":"MediScan: A Framework of U-Health and Prognostic AI Assessment on Medical Imaging.","authors":"Sibtain Syed, Rehan Ahmed, Arshad Iqbal, Naveed Ahmad, Mohammed Ali Alshara","doi":"10.3390/jimaging10120322","DOIUrl":"10.3390/jimaging10120322","url":null,"abstract":"<p><p>With technological advancements, remarkable progress has been made with the convergence of health sciences and Artificial Intelligence (AI). Modern health systems are proposed to ease patient diagnostics. However, the challenge is to provide AI-based precautions to patients and doctors for more accurate risk assessment. The proposed healthcare system aims to integrate patients, doctors, laboratories, pharmacies, and administrative personnel use cases and their primary functions onto a single platform. The proposed framework can also process microscopic images, CT scans, X-rays, and MRI to classify malignancy and give doctors a set of AI precautions for patient risk assessment. The proposed framework incorporates various DCNN models for identifying different forms of tumors and fractures in the human body i.e., brain, bones, lungs, kidneys, and skin, and generating precautions with the help of the Fined-Tuned Large Language Model (LLM) i.e., Generative Pretrained Transformer 4 (GPT-4). With enough training data, DCNN can learn highly representative, data-driven, hierarchical image features. The GPT-4 model is selected for generating precautions due to its explanation, reasoning, memory, and accuracy on prior medical assessments and research studies. Classification models are evaluated by classification report (i.e., Recall, Precision, F1 Score, Support, Accuracy, and Macro and Weighted Average) and confusion matrix and have shown robust performance compared to the conventional schemes.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved Generalizability in Medical Computer Vision: Hyperbolic Deep Learning in Multi-Modality Neuroimaging. 医学计算机视觉的改进泛化:多模态神经成像中的双曲深度学习。
IF 2.7
Journal of Imaging Pub Date : 2024-12-12 DOI: 10.3390/jimaging10120319
Cyrus Ayubcha, Sulaiman Sajed, Chady Omara, Anna B Veldman, Shashi B Singh, Yashas Ullas Lokesha, Alex Liu, Mohammad Ali Aziz-Sultan, Timothy R Smith, Andrew Beam
{"title":"Improved Generalizability in Medical Computer Vision: Hyperbolic Deep Learning in Multi-Modality Neuroimaging.","authors":"Cyrus Ayubcha, Sulaiman Sajed, Chady Omara, Anna B Veldman, Shashi B Singh, Yashas Ullas Lokesha, Alex Liu, Mohammad Ali Aziz-Sultan, Timothy R Smith, Andrew Beam","doi":"10.3390/jimaging10120319","DOIUrl":"10.3390/jimaging10120319","url":null,"abstract":"<p><p>Deep learning has shown significant value in automating radiological diagnostics but can be limited by a lack of generalizability to external datasets. Leveraging the geometric principles of non-Euclidean space, certain geometric deep learning approaches may offer an alternative means of improving model generalizability. This study investigates the potential advantages of hyperbolic convolutional neural networks (HCNNs) over traditional convolutional neural networks (CNNs) in neuroimaging tasks. We conducted a comparative analysis of HCNNs and CNNs across various medical imaging modalities and diseases, with a focus on a compiled multi-modality neuroimaging dataset. The models were assessed for their performance parity, robustness to adversarial attacks, semantic organization of embedding spaces, and generalizability. Zero-shot evaluations were also performed with ischemic stroke non-contrast CT images. HCNNs matched CNNs' performance in less complex settings and demonstrated superior semantic organization and robustness to adversarial attacks. While HCNNs equaled CNNs in out-of-sample datasets identifying Alzheimer's disease, in zero-shot evaluations, HCNNs outperformed CNNs and radiologists. HCNNs deliver enhanced robustness and organization in neuroimaging data. This likely underlies why, while HCNNs perform similarly to CNNs with respect to in-sample tasks, they confer improved generalizability. Nevertheless, HCNNs encounter efficiency and performance challenges with larger, complex datasets. These limitations underline the need for further optimization of HCNN architectures. HCNNs present promising improvements in generalizability and resilience for medical imaging applications, particularly in neuroimaging. Despite facing challenges with larger datasets, HCNNs enhance performance under adversarial conditions and offer better semantic organization, suggesting valuable potential in generalizable deep learning models in medical imaging and neuroimaging diagnostics.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11676359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-Level Feature Fusion in CNN-Based Human Action Recognition: A Case Study on EfficientNet-B7. 基于cnn的多层次特征融合人体动作识别——以高效网络b7为例
IF 2.7
Journal of Imaging Pub Date : 2024-12-12 DOI: 10.3390/jimaging10120320
Pitiwat Lueangwitchajaroen, Sitapa Watcharapinchai, Worawit Tepsan, Sorn Sooksatra
{"title":"Multi-Level Feature Fusion in CNN-Based Human Action Recognition: A Case Study on EfficientNet-B7.","authors":"Pitiwat Lueangwitchajaroen, Sitapa Watcharapinchai, Worawit Tepsan, Sorn Sooksatra","doi":"10.3390/jimaging10120320","DOIUrl":"10.3390/jimaging10120320","url":null,"abstract":"<p><p>Accurate human action recognition is becoming increasingly important across various fields, including healthcare and self-driving cars. A simple approach to enhance model performance is incorporating additional data modalities, such as depth frames, point clouds, and skeleton information, while previous studies have predominantly used late fusion techniques to combine these modalities, our research introduces a multi-level fusion approach that combines information at early, intermediate, and late stages together. Furthermore, recognizing the challenges of collecting multiple data types in real-world applications, our approach seeks to exploit multimodal techniques while relying solely on RGB frames as the single data source. In our work, we used RGB frames from the NTU RGB+D dataset as the sole data source. From these frames, we extracted 2D skeleton coordinates and optical flow frames using pre-trained models. We evaluated our multi-level fusion approach with EfficientNet-B7 as a case study, and our methods demonstrated significant improvement, achieving 91.5% in NTU RGB+D 60 dataset accuracy compared to single-modality and single-view models. Despite their simplicity, our methods are also comparable to other state-of-the-art approaches.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11677249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-Dimensional Bone-Image Synthesis with Generative Adversarial Networks. 基于生成对抗网络的三维骨图像合成。
IF 2.7
Journal of Imaging Pub Date : 2024-12-11 DOI: 10.3390/jimaging10120318
Christoph Angermann, Johannes Bereiter-Payr, Kerstin Stock, Gerald Degenhart, Markus Haltmeier
{"title":"Three-Dimensional Bone-Image Synthesis with Generative Adversarial Networks.","authors":"Christoph Angermann, Johannes Bereiter-Payr, Kerstin Stock, Gerald Degenhart, Markus Haltmeier","doi":"10.3390/jimaging10120318","DOIUrl":"10.3390/jimaging10120318","url":null,"abstract":"<p><p>Medical image processing has been highlighted as an area where deep-learning-based models have the greatest potential. However, in the medical field, in particular, problems of data availability and privacy are hampering research progress and, thus, rapid implementation in clinical routine. The generation of synthetic data not only ensures privacy but also allows the drawing of new patients with specific characteristics, enabling the development of data-driven models on a much larger scale. This work demonstrates that three-dimensional generative adversarial networks (GANs) can be efficiently trained to generate high-resolution medical volumes with finely detailed voxel-based architectures. In addition, GAN inversion is successfully implemented for the three-dimensional setting and used for extensive research on model interpretability and applications such as image morphing, attribute editing, and style mixing. The results are comprehensively validated on a database of three-dimensional HR-pQCT instances representing the bone micro-architecture of the distal radius.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11678923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Color Difference Models for Wide Color Gamut and High Dynamic Range. 大色域和高动态范围的色差模型评价。
IF 2.7
Journal of Imaging Pub Date : 2024-12-10 DOI: 10.3390/jimaging10120317
Olga Basova, Sergey Gladilin, Vladislav Kokhan, Mikhalina Kharkevich, Anastasia Sarycheva, Ivan Konovalenko, Mikhail Chobanu, Ilya Nikolaev
{"title":"Evaluation of Color Difference Models for Wide Color Gamut and High Dynamic Range.","authors":"Olga Basova, Sergey Gladilin, Vladislav Kokhan, Mikhalina Kharkevich, Anastasia Sarycheva, Ivan Konovalenko, Mikhail Chobanu, Ilya Nikolaev","doi":"10.3390/jimaging10120317","DOIUrl":"10.3390/jimaging10120317","url":null,"abstract":"<p><p>Color difference models (CDMs) are essential for accurate color reproduction in image processing. While CDMs aim to reflect perceived color differences (CDs) from psychophysical data, they remain largely untested in wide color gamut (WCG) and high dynamic range (HDR) contexts, which are underrepresented in current datasets. This gap highlights the need to validate CDMs across WCG and HDR. Moreover, the non-geodesic structure of perceptual color space necessitates datasets covering CDs of various magnitudes, while most existing datasets emphasize only small and threshold CDs. To address this, we collected a new dataset encompassing a broad range of CDs in WCG and HDR contexts and developed a novel CDM fitted to these data. Benchmarking various CDMs using STRESS and significant error fractions on both new and established datasets reveals that CAM16-UCS with power correction is the most versatile model, delivering strong average performance across WCG colors up to 1611 cd/m<sup>2</sup>. However, even the best CDM fails to achieve the desired accuracy limits and yields significant errors. CAM16-UCS, though promising, requires further refinement, particularly in its power correction component to better capture the non-geodesic structure of perceptual color space.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11676281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System. PAS还是不PAS?胎盘增生谱系障碍的超声评估及一种新的诊断和预后评分系统的临床验证。
IF 2.7
Journal of Imaging Pub Date : 2024-12-10 DOI: 10.3390/jimaging10120315
Antonella Vimercati, Arianna Galante, Margherita Fanelli, Francesca Cirignaco, Amerigo Vitagliano, Pierpaolo Nicolì, Andrea Tinelli, Antonio Malvasi, Miriam Dellino, Gianluca Raffaello Damiani, Barbara Crescenza, Giorgio Maria Baldini, Ettore Cicinelli, Marco Cerbone
{"title":"PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System.","authors":"Antonella Vimercati, Arianna Galante, Margherita Fanelli, Francesca Cirignaco, Amerigo Vitagliano, Pierpaolo Nicolì, Andrea Tinelli, Antonio Malvasi, Miriam Dellino, Gianluca Raffaello Damiani, Barbara Crescenza, Giorgio Maria Baldini, Ettore Cicinelli, Marco Cerbone","doi":"10.3390/jimaging10120315","DOIUrl":"10.3390/jimaging10120315","url":null,"abstract":"<p><p>This study aimed to evaluate our center's experience in diagnosing and managing placenta accreta spectrum (PAS) in a high-risk population, focusing on prenatal ultrasound features associated with PAS severity and maternal outcomes. We conducted a retrospective analysis of 102 high-risk patients with confirmed placenta previa who delivered at our center between 2018 and 2023. Patients underwent transabdominal and transvaginal ultrasound scans, assessing typical sonographic features. Binary and multivariate logistic regression analyses were performed to identify sonographic markers predictive of PAS and relative complications. Key ultrasound features-retroplacental myometrial thinning (<1 mm), vascular lacunae, and retroplacental vascularization-were significantly associated with PAS and a higher risk of surgical complications. An exceedingly rare sign, the \"riddled cervix\" sign, was observed in only three patients with extensive cervical or parametrial involvement. Those patients had the worst surgical outcomes. This study highlights the utility of specific ultrasound features in stratifying PAS risk and guiding clinical and surgical management in high-risk pregnancies. The findings support integrating these markers into prenatal diagnostic protocols to improve patient outcomes and inform surgical planning.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11676445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward Closing the Loop in Image-to-Image Conversion in Radiotherapy: A Quality Control Tool to Predict Synthetic Computed Tomography Hounsfield Unit Accuracy. 放射治疗中图像到图像转换的闭环:预测合成计算机断层扫描霍斯菲尔德单元精度的质量控制工具。
IF 2.7
Journal of Imaging Pub Date : 2024-12-10 DOI: 10.3390/jimaging10120316
Paolo Zaffino, Ciro Benito Raggio, Adrian Thummerer, Gabriel Guterres Marmitt, Johannes Albertus Langendijk, Anna Procopio, Carlo Cosentino, Joao Seco, Antje Christin Knopf, Stefan Both, Maria Francesca Spadea
{"title":"Toward Closing the Loop in Image-to-Image Conversion in Radiotherapy: A Quality Control Tool to Predict Synthetic Computed Tomography Hounsfield Unit Accuracy.","authors":"Paolo Zaffino, Ciro Benito Raggio, Adrian Thummerer, Gabriel Guterres Marmitt, Johannes Albertus Langendijk, Anna Procopio, Carlo Cosentino, Joao Seco, Antje Christin Knopf, Stefan Both, Maria Francesca Spadea","doi":"10.3390/jimaging10120316","DOIUrl":"10.3390/jimaging10120316","url":null,"abstract":"<p><p>In recent years, synthetic Computed Tomography (CT) images generated from Magnetic Resonance (MR) or Cone Beam Computed Tomography (CBCT) acquisitions have been shown to be comparable to real CT images in terms of dose computation for radiotherapy simulation. However, until now, there has been no independent strategy to assess the quality of each synthetic image in the absence of ground truth. In this work, we propose a Deep Learning (DL)-based framework to predict the accuracy of synthetic CT in terms of Mean Absolute Error (MAE) without the need for a ground truth (GT). The proposed algorithm generates a volumetric map as an output, informing clinicians of the predicted MAE slice-by-slice. A cascading multi-model architecture was used to deal with the complexity of the MAE prediction task. The workflow was trained and tested on two cohorts of head and neck cancer patients with different imaging modalities: 27 MR scans and 33 CBCT. The algorithm evaluation revealed an accurate HU prediction (a median absolute prediction deviation equal to 4 HU for CBCT-based synthetic CTs and 6 HU for MR-based synthetic CTs), with discrepancies that do not affect the clinical decisions made on the basis of the proposed estimation. The workflow exhibited no systematic error in MAE prediction. This work represents a proof of concept about the feasibility of synthetic CT evaluation in daily clinical practice, and it paves the way for future patient-specific quality assessment strategies.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11679912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Regularization Method for Landslide Thickness Estimation. 滑坡厚度估计的正则化方法。
IF 2.7
Journal of Imaging Pub Date : 2024-12-10 DOI: 10.3390/jimaging10120314
Lisa Borgatti, Davide Donati, Liwei Hu, Germana Landi, Fabiana Zama
{"title":"A Regularization Method for Landslide Thickness Estimation.","authors":"Lisa Borgatti, Davide Donati, Liwei Hu, Germana Landi, Fabiana Zama","doi":"10.3390/jimaging10120314","DOIUrl":"10.3390/jimaging10120314","url":null,"abstract":"<p><p>Accurate estimation of landslide depth is essential for practical hazard assessment and risk mitigation. This work addresses the problem of determining landslide depth from satellite-derived elevation data. Using the principle of mass conservation, this problem can be formulated as a linear inverse problem. To solve the inverse problem, we present a regularization approach that computes approximate solutions and regularization parameters using the Balancing Principle. Synthetic data were carefully designed and generated to evaluate the method under controlled conditions, allowing for precise validation of its performance. Through comprehensive testing with this synthetic dataset, we demonstrate the method's robustness across varying noise levels. When applied to real-world data from the Fels landslide in Alaska, the proposed method proved its practical value in reconstructing landslide thickness patterns. These reconstructions showed good agreement with existing geological interpretations, validating the method's effectiveness in real-world scenarios.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11678178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-Time Emotion Recognition for Improving the Teaching-Learning Process: A Scoping Review. 实时情绪识别改善教-学过程:范围检讨。
IF 2.7
Journal of Imaging Pub Date : 2024-12-09 DOI: 10.3390/jimaging10120313
Cèlia Llurba, Ramon Palau
{"title":"Real-Time Emotion Recognition for Improving the Teaching-Learning Process: A Scoping Review.","authors":"Cèlia Llurba, Ramon Palau","doi":"10.3390/jimaging10120313","DOIUrl":"10.3390/jimaging10120313","url":null,"abstract":"<p><p>Emotion recognition (ER) is gaining popularity in various fields, including education. The benefits of ER in the classroom for educational purposes, such as improving students' academic performance, are gradually becoming known. Thus, real-time ER is proving to be a valuable tool for teachers as well as for students. However, its feasibility in educational settings requires further exploration. This review offers learning experiences based on real-time ER with students to explore their potential in learning and in improving their academic achievement. The purpose is to present evidence of good implementation and suggestions for their successful application. The content analysis finds that most of the practices lead to significant improvements in terms of educational purposes. Nevertheless, the analysis identifies problems that might block the implementation of these practices in the classroom and in education; among the obstacles identified are the absence of privacy of the students and the support needs of the students. We conclude that artificial intelligence (AI) and ER are potential tools to approach the needs in ordinary classrooms, although reliable automatic recognition is still a challenge for researchers to achieve the best ER feature in real time, given the high input data variability.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11677434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative MRI Assessment of Post-Surgical Spinal Cord Injury Through Radiomic Analysis. 通过放射组学分析定量MRI评估术后脊髓损伤。
IF 2.7
Journal of Imaging Pub Date : 2024-12-08 DOI: 10.3390/jimaging10120312
Azadeh Sharafi, Andrew P Klein, Kevin M Koch
{"title":"Quantitative MRI Assessment of Post-Surgical Spinal Cord Injury Through Radiomic Analysis.","authors":"Azadeh Sharafi, Andrew P Klein, Kevin M Koch","doi":"10.3390/jimaging10120312","DOIUrl":"10.3390/jimaging10120312","url":null,"abstract":"<p><p>This study investigates radiomic efficacy in post-surgical traumatic spinal cord injury (SCI), overcoming MRI limitations from metal artifacts to enhance diagnosis, severity assessment, and lesion characterization or prognosis and therapy guidance. Traumatic spinal cord injury (SCI) causes severe neurological deficits. While MRI allows qualitative injury evaluation, standard imaging alone has limitations for precise SCI diagnosis, severity stratification, and pathology characterization, which are needed to guide prognosis and therapy. Radiomics enables quantitative tissue phenotyping by extracting a high-dimensional set of descriptive texture features from medical images. However, the efficacy of postoperative radiomic quantification in the presence of metal-induced MRI artifacts from spinal instrumentation has yet to be fully explored. A total of 50 healthy controls and 12 SCI patients post-stabilization surgery underwent 3D multi-spectral MRI. Automated spinal cord segmentation was followed by radiomic feature extraction. Supervised machine learning categorized SCI versus controls, injury severity, and lesion location relative to instrumentation. Radiomics differentiated SCI patients (Matthews correlation coefficient (MCC) 0.97; accuracy 1.0), categorized injury severity (MCC: 0.95; ACC: 0.98), and localized lesions (MCC: 0.85; ACC: 0.90). Combined T<sub>1</sub> and T<sub>2</sub> features outperformed individual modalities across tasks with gradient boosting models showing the highest efficacy. The radiomic framework achieved excellent performance, differentiating SCI from controls and accurately categorizing injury severity. The ability to reliably quantify SCI severity and localization could potentially inform diagnosis, prognosis, and guide therapy. Further research is warranted to validate radiomic SCI biomarkers and explore clinical integration.</p>","PeriodicalId":37035,"journal":{"name":"Journal of Imaging","volume":"10 12","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11678099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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