CJC Open最新文献

{"title":"Smoking, Colchicine and Postoperative Outcomes in Thoracic Surgery: Post Hoc Analysis of the COP-AF Randomized Controlled Trial","authors":"Sandra Ofori MBBS, PhD ,&nbsp;Michael K. Wang MD ,&nbsp;Ekaterine Popova MD, PhD ,&nbsp;William F. McIntyre MD, PhD ,&nbsp;Matthew Chan MBBS, PhD ,&nbsp;Daniel I. Sessler MD ,&nbsp;Veronesi Giulia MD ,&nbsp;Mark Warwas MD ,&nbsp;Kumar Balasubramanian MSc ,&nbsp;Vikas Tandon MD ,&nbsp;Christain Finley MD, MPH ,&nbsp;Gonzalez Tallada Anna MD ,&nbsp;Juan Cata MD ,&nbsp;Sadeesh Srinathan MD ,&nbsp;Cara Reimer MD ,&nbsp;Sean McLean MD, FRCPC ,&nbsp;Juan Carlos Trujillo MD, PhD ,&nbsp;Edith Fleischmann MD ,&nbsp;Luca Voltolini MD ,&nbsp;Patricia Cruz MD ,&nbsp;David Conen MD, MPH","doi":"10.1016/j.cjco.2025.04.008","DOIUrl":"10.1016/j.cjco.2025.04.008","url":null,"abstract":"<div><h3>Background</h3><div>To determine, among patients who underwent major noncardiac thoracic surgery, the association between smoking and perioperative atrial fibrillation (AF) and myocardial injury after noncardiac surgery (MINS), and whether the effect of colchicine use on these outcomes varied by smoking status.</div></div><div><h3>Methods</h3><div>This study is a subgroup analysis of the Colchicine for the Prevention of Perioperative Atrial Fibrillation (COP-AF) randomized clinical trial. A total of 3209 participants who underwent major noncardiac thoracic surgery were randomized to receive colchicine, 0.5 mg twice daily, or identical placebo, for 10 days starting 2-4 hours before surgery. The co-primary outcomes were clinically significant perioperative AF and MINS during the 14-day follow-up.</div></div><div><h3>Results</h3><div>A total of 687 (21.4%) were current smokers, 1577 (49.1%) were former smokers, and 945 (29.5%) were never smokers. AF occurred in 7.7%, 7.6%, and 5.3%, and MINS occurred in 21.0%, 19.7%, and 17.6% of current, former, and never smokers, respectively. Compared to never smokers, the adjusted hazard ratio for AF was 1.72 (95% confidence interval [CI] 1.07-2.77, <em>P</em> = 0.02) in current smokers and 1.46 (95% CI 0.99-2.16, <em>P</em> = 0.06) in former smokers, and the adjusted hazard ratio for MINS was 1.16 (95% CI 0.87-1.54, <em>P</em> = 0.32) in current smokers and 1.02 (95% CI 0.81-1.28, <em>P</em> = 0.88) in former smokers. No interaction occurred between smoking status and colchicine allocation for AF (interaction <em>P,</em> 0.82) or MINS (interaction <em>P</em>, 0.08).</div></div><div><h3>Conclusions</h3><div>Current smoking was associated with a small but increased risk of perioperative AF but not MINS after thoracic surgery. The effect of colchicine use on either outcome was not modified by smoking status.</div></div><div><h3>Clinical Trial Registration</h3><div><span><span>NCT03310125</span><svg><path></path></svg></span></div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 7","pages":"Pages 860-870"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empowering Korean Immigrant Women Through Culturally Tailored Cardiovascular Health Education: An Educational Tool Creation","authors":"L. Moon,&nbsp;N. Tegg,&nbsp;C.M. Norris","doi":"10.1016/j.cjco.2025.04.052","DOIUrl":"10.1016/j.cjco.2025.04.052","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages S13-S14"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraception and Rheumatic Heart Disease in Ethiopia: A Tertiary Hospital Experience","authors":"A. Weldehana,&nbsp;S. Zewde,&nbsp;S. Negash,&nbsp;D. Andualem","doi":"10.1016/j.cjco.2025.04.022","DOIUrl":"10.1016/j.cjco.2025.04.022","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages S2-S3"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Pregnancy on the Progression of Aortic and Aortic Valve Disease in Patients With Bicuspid Aortic Valves","authors":"K. Abdoun ,&nbsp;M. Fortin ,&nbsp;L. Brunet ,&nbsp;M. Shen,&nbsp;É. Bédard,&nbsp;P. Chetaille,&nbsp;M.-A. Clavel","doi":"10.1016/j.cjco.2025.04.032","DOIUrl":"10.1016/j.cjco.2025.04.032","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Page S6"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Determinants of Cardiovascular Health in Métis Women: The Role of Adverse Childhood and Discrimination Experiences, Social Support, and Physical Fitness","authors":"S. Johnson,&nbsp;S. Moore,&nbsp;G. Selinger,&nbsp;J. LaFleur,&nbsp;M. Fatima,&nbsp;H. Foulds","doi":"10.1016/j.cjco.2025.04.062","DOIUrl":"10.1016/j.cjco.2025.04.062","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Page S17"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Patient Care for Women’s Heart Health by Increasing Women’s Heart Health Education","authors":"Z. Koopman,&nbsp;M. Sergerie,&nbsp;N. Parast,&nbsp;B. Quinlan","doi":"10.1016/j.cjco.2025.04.058","DOIUrl":"10.1016/j.cjco.2025.04.058","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Page S16"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Provider Toolkit for the Post-Pregnancy Cardiovascular Assessment of Patients With a Hypertensive Disorder of Pregnancy","authors":"J. Rao,&nbsp;M. Shireen,&nbsp;I. Wirsig,&nbsp;T. Johannsen,&nbsp;N. Leung,&nbsp;L. Dubrofsky,&nbsp;D. Elman,&nbsp;K. Fleming","doi":"10.1016/j.cjco.2025.04.059","DOIUrl":"10.1016/j.cjco.2025.04.059","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Page S16"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Series of Unfortunate Events: A Unique Case of Eosinophilic Vasospasm, Recurrent Myocardial Infarction, and Allergy to Steroid and Naproxen","authors":"Sarah A. Miner BSc ,&nbsp;Laurie-Anne Boivin-Proulx MD, FRCPC ,&nbsp;Mary McCarthy NP ,&nbsp;Lynne E. Nield MD, FRCPC ,&nbsp;Steven E.S. Miner MD, FRCPC","doi":"10.1016/j.cjco.2025.03.023","DOIUrl":"10.1016/j.cjco.2025.03.023","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages 725-727"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intussusception of the Left Atrial Appendage: A Systematic Review","authors":"Riccardo Scagliola MD ,&nbsp;Giancarlo Passerone MD ,&nbsp;Manrico Balbi MD","doi":"10.1016/j.cjco.2025.04.002","DOIUrl":"10.1016/j.cjco.2025.04.002","url":null,"abstract":"<div><h3>Background</h3><div>Intussusception of the left atrial appendage (LAA) is an uncommon and often underrecognized finding; poor knowledge of this condition is still widespread in clinical practice. A systematic review was carried out to provide a comprehensive and updated overview on this condition.</div></div><div><h3>Methods</h3><div>A bibliographic search using major databases resulted in 25 case reports meeting the criteria. Included records reported data from patients aged &gt; 18 years with a diagnosis of LAA intussusception, determined either intraoperatively or incidentally by imaging tools, and findings on baseline demographics, clinical findings, imaging diagnostic workup, and management.</div></div><div><h3>Results</h3><div>For the 25 patients included, the median age was 54 years, with a predominance of female sex (53%). Most of intussuscepted LAA cases were disclosed intraoperatively (60%) or incidentally by imaging tools (20%) in the absence of associated clinical findings. All reported cases underwent transoesophageal echocardiography, and in most, LAA intussusception was confirmed by intraoperative inspection (44%) or further imaging (23%). In most cases, LAA intussusception was resolved interventionally (60%). In fewer subjects, LAA eversion occurred spontaneously (32%), and in the remaining cases, a conservative approach was adopted (8%).</div></div><div><h3>Conclusions</h3><div>This study presents the largest systematic review to date of an adult patient population with a diagnosis of intussuscepted LAA. Regardless of the various etiologies and clinical manifestations associated with LAA intussusception, physicians should be aware of the possibility of this rare entity, to provide timely recognition and thereby avoid misleading diagnoses and enable appropriate decision-making.</div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages 768-776"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural History of Cardiovascular Disease in Young Women: Cardiometabolic Risk, Atherosclerotic Cardiovascular Disease and Cardiac Function Is Exacerbated in Those With Polycystic Ovary Syndrome","authors":"X. Wu,&nbsp;Ghosh M,&nbsp;H. Becher,&nbsp;J. Windram,&nbsp;K. Nadeau,&nbsp;M. Cree,&nbsp;D. Vine","doi":"10.1016/j.cjco.2025.04.047","DOIUrl":"10.1016/j.cjco.2025.04.047","url":null,"abstract":"","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 6","pages":"Pages S11-S12"},"PeriodicalIF":2.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}