{"title":"Confocal spatial filtering for imaging with ballistic light in transillumination","authors":"M. Kempe, J. Wong, A. Z. Genack","doi":"10.1364/aoipm.1996.pmst25","DOIUrl":"https://doi.org/10.1364/aoipm.1996.pmst25","url":null,"abstract":"The detection of ballistic and diffuse light in confocal imaging in transillumination is investigated. We find an optimum pinhole size for detection of ballistic and suppression of diffuse light. The limits of confocal imaging with ballistic light are primarily determined by sample parameters. Spherical aberration introduced by the sample is a major limiting factor for high resolution imaging. In the aberration free case and for sample and illumination characteristics which are typical for biomedical imaging, the limits of ballistic light detection in confocal imaging are close to the noise limits of standard detectors.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"518 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116240262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Perelman, J. Wu, I. Itzkan, Y. Wang, R. Dasari, M. Feld
{"title":"Photon Paths in Turbid Media: Theory and Experimental Observation","authors":"L. Perelman, J. Wu, I. Itzkan, Y. Wang, R. Dasari, M. Feld","doi":"10.1364/aoipm.1994.trbsdi.153","DOIUrl":"https://doi.org/10.1364/aoipm.1994.trbsdi.153","url":null,"abstract":"We present a new approach to the problem of light propagation in turbid media based on the path integral formalism. The theory and experiments show that photons traveling in turbid media follow well-defined time-resolved path.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116343373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vivo Measurement of Reduced Scattering and Absorption Coefficients of Living Tissue using Time-Resolved Spectroscopy","authors":"Y. Yamashita, M. Oda, H. Naruse, M. Tamura","doi":"10.1364/aoipm.1996.opc387","DOIUrl":"https://doi.org/10.1364/aoipm.1996.opc387","url":null,"abstract":"Reduced scattering and absorption coefficients of piglet head were measured in-vivo by analyzing the observed temporal responses based on the diffusion theory. The reduced scattering and absorption coefficients in normoxic condition were around 1.3 and 0.013 [mm-1], respectively, at the wavelength of 760nm. When hypoxia was induced, the absorption coefficient was increasing, while the scattering coefficient was constant. It was suggested that in-vivo measurement of the optical parameters in piglet head was possible based on the photon diffusion theory.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"386 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123391281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterodyne Measurement of Wigner Phase Space Distributions in Turbid Media","authors":"A. Wax, J. Thomas","doi":"10.1364/aoipm.1996.cit238","DOIUrl":"https://doi.org/10.1364/aoipm.1996.cit238","url":null,"abstract":"We demonstrate a method for heterodyne detection of Wigner phase space distributions in turbid media, with a dynamic range of 13 orders of magnitude for 1 mW input and local oscillator beams.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127090503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frequency-Domain Optical Image Reconstruction: Initial Experimental Studies on Contrast and Resolution Limits","authors":"Huabei Jiang, K. Paulsen, U. Österberg","doi":"10.1364/aoipm.1996.mt152","DOIUrl":"https://doi.org/10.1364/aoipm.1996.mt152","url":null,"abstract":"Recent progress in near infrared frequency-domain optical image reconstruction based on laboratory data is reported. Particular attention is given to the important issues of imaging contrast and resolution.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127397648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Demos, H. Savage, A. Heerdt, S. Schantz, R. Alfano
{"title":"Polarization Imaging and Characterization of Human Breast Tissue.","authors":"S. Demos, H. Savage, A. Heerdt, S. Schantz, R. Alfano","doi":"10.1364/aoipm.1996.trit113","DOIUrl":"https://doi.org/10.1364/aoipm.1996.trit113","url":null,"abstract":"Laser pulses propagating in human breast tissue depolarize to different degree depending on the type of tissue and wavelength over a time domain of ≈100 ps. This feature allows for optical imaging and characterization of the different components composing the tissue.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128942308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phase Statistics in Random Media","authors":"P. Sebbah, O. Legrand, A. Z. Genack","doi":"10.1364/aoipm.1996.opc386","DOIUrl":"https://doi.org/10.1364/aoipm.1996.opc386","url":null,"abstract":"Because the ensemble average of the field transmitted through a random medium tends to zero as the sample length increases, studies of wave propagation in random media have focused upon the field amplitude or its square, the intensity, whose statistical properties have been extensively investigated. In this paper, we show that, beyond the random phase approximation, the phase remains a rich statistical quantity which is central to the understanding of wave transport in random systems. We define the cumulative phase φ and present measurements of the frequency dependence of its average, its probability distribution and the correlation function of the phase derivative for microwave radiation transmitted through random collections of polystyrene spheres. Static field measurements are made using a network analyzer. The phase and amplitude of the wave as a function of frequency is obtained for an ensemble of samples by rotating the sample after each spectrum is taken. The probability distribution is calculated using the phase measurement at each frequency for every configuration and is found to reduce to a single gaussian in terms of the variable (φ-)/σ, where σ = (var(φ))½. We show that this is a direct result of the rapid decay of the frequency correlation function of phase derivative found at any frequency. We compare the dwell time Δτ(ν), which is the time for a gaussian pulse with carrier frequency ν to traverse the sample, with phase derivative dφ/dω(ν), where ω = 2πν. We demonstrate theoretically and experimentally that these two quantities are identical if the frequency width of the gaussian pulse is narrow enough (Fig. 1). Finally we outline some of the ways in which φ reflects wave dynamics and relate the phase derivative with the density of states.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130539235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Origins of Tissue Optical Properties in the UVA, Visible, and NIR Regions","authors":"S. Jacques","doi":"10.1364/aoipm.1996.opc364","DOIUrl":"https://doi.org/10.1364/aoipm.1996.opc364","url":null,"abstract":"This paper describes the relationship between the ultrastructure of biological tissues and the observed macroscopic optical scattering properties. A summary of the tissue absorption spectrum is also presented. The scattering of soft tissues (liver, prostate, etc.) and fibrous tissues such as dermis are considered. The scattering of soft tissues is attribued to membranous structures and modeled as Mie scattering from spheres in the 0.2-2-μm diameter range, where membrane lipids occupy about 1-20% of the cellular volume and the refractive index mismatch is 1.46/1.35. The scattering of dermis is modeled as scattering from collagen fiber bundles in the 2.8-μm diameter range occupying 21% of the dermal volume and the refractive index mismatch is 1.38/1.35. The effects of a component of small-scale particle scattering in the Rayleigh limit is also considered. The models are compared with tissue values from the literature for the reduced scattering coefficient, μs(1-g), and the anisotropy, g. The models roughly match the absolute value and wavelength dependence of scattering in the 300-1100 nm wavelength range.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130566990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wave Automaton for Wave Propagation in Random Media","authors":"P. Sebbah, D. Sornette, C. Vanneste","doi":"10.1364/aoipm.1994.wpl.68","DOIUrl":"https://doi.org/10.1364/aoipm.1994.wpl.68","url":null,"abstract":"We present an original numerical approach for investigation of time-dependent wave propagation in random media. We review different results in 2D, including subdiffusive regime characterization, NDE in the multiple scattering regime and Anderson localization in presence of a nonlinear local gain.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123229158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Multichannel Approach To Coherent Optical Imaging Through Turbid Media","authors":"P. Gleyzes, H. Saint-Jalmes, A. Boccara","doi":"10.1364/aoipm.1996.cit234","DOIUrl":"https://doi.org/10.1364/aoipm.1996.cit234","url":null,"abstract":"We present two experimental set-ups used for imaging through scattering media : a Mach-Zehnder interferometer, working in transmission, and a Nomarski microscope, working in reflection. Both systems, equipped with an array of detectors, take advantage of multichannel lock-in detection schemes.","PeriodicalId":368664,"journal":{"name":"Advances in Optical Imaging and Photon Migration","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122173698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}