Open Journal of Bioresources最新文献_第3页

The Northern Ireland Biobank: A Cancer Focused Repository of Science 北爱尔兰生物银行:一个以癌症为重点的科学资料库

Open Journal of Bioresources Pub Date : 2018-09-11 DOI: 10.5334/OJB.47

C. Lewis, S. McQuaid, Priscilla Clark, P. Murray, T. McGuigan, Christine Greene, Bronagh Coulter, K. Mills, J. James

引用次数: 25

Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study: A Large Multicenter Clinical Biobank with Standardized Collection and Storage 荷兰paressnoer研究所脑血管事故(CVA)研究:一个标准化收集和储存的大型多中心临床生物库

Open Journal of Bioresources Pub Date : 2018-07-19 DOI: 10.5334/OJB.41

H. J. V. Os, Y. Ruigrok, J. Manniën, E. Dijk, P. Koudstaal, G. Luijckx, P. Nederkoorn, R. Oostenbrugge, M. Visser, L. Kappelle, A. Algra, M. Wermer

{"title":"Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study: A Large Multicenter Clinical Biobank with Standardized Collection and Storage","authors":"H. J. V. Os, Y. Ruigrok, J. Manniën, E. Dijk, P. Koudstaal, G. Luijckx, P. Nederkoorn, R. Oostenbrugge, M. Visser, L. Kappelle, A. Algra, M. Wermer","doi":"10.5334/OJB.41","DOIUrl":"https://doi.org/10.5334/OJB.41","url":null,"abstract":"The Dutch Parelsnoer Institute-Cerebrovascular accident (CVA) Study is part of the Parelsnoer Institute (PSI), initiated in 2007 by the Netherlands Federation of University Medical Centers (NFU). PSI is a cooperation of all eight Dutch University Medical Centers (UMCs) and aims at building large prospectively collected datasets with uniformly and standardized storage of biomaterials for complex diseases. Currently, PSI covers 18 disease-specific cohorts called ‘Pearls’, and this number is still growing. One of these cohorts is the Stroke or CVA Pearl. For each of the cohorts, PSI offers the UMCs an infrastructure and standard procedures for storing the specific biomaterials in their certified biobanks. Clinical data are stored in a central database after being pseudonymized to ensure patient privacy. For the Parelsnoer Institute-CVA Study, blood for genetic analysis, serum and plasma are collected according to nationally agreed standards. Currently (November 2017) the Stroke Pearl has stored blood samples with prospectively obtained clinical data of around 6000 patients in all UMCs combined. Blood samples and data are available for all researchers with a methodologically valid research proposal. Funding statement: PSI was founded in 2007 with a five year grant from the Dutch Government. From 2011 until now PSI is funded and facilitated by the Netherlands Federation of University Medical Centers (NFU) and its member institutions, independent of external funds. Additional funds from governmental sources, industry sponsors and charity are used for the analysis on the existing data and the expansion of PSI with new diseases.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42232625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bimetra Biobank: A High Quality Biobank Facility to Stimulate Translational Biomedical Research Bimetra生物库:一个高质量的生物库设施，以促进转化生物医学研究

Open Journal of Bioresources Pub Date : 2018-04-23 DOI: 10.5334/OJB.37

V. T'joen, Sara Phlypo, S. Bekaert

引用次数: 5

Hospital-integrated Biobanking as a Service – The Interdisciplinary Bank of Biomaterials and Data Wuerzburg (ibdw) 医院综合生物银行服务——维尔茨堡生物材料和数据跨学科银行（ibdw）

Open Journal of Bioresources Pub Date : 2018-04-23 DOI: 10.5334/OJB.38

J. Geiger, S. Both, S. Kircher, Michael Neumann, A. Rosenwald, R. Jahns

引用次数: 15

Tumorbank@uza: A Collection of Tissue, Fluid Samples and Associated Data of Oncology Patients for the Use in Translational Research Tumorbank@uza：肿瘤患者的组织、液体样本和相关数据的收集，用于转化研究

Open Journal of Bioresources Pub Date : 2018-02-06 DOI: 10.5334/OJB.30

S. Goethals, A. D. Wilde, Katrien Lesage, E. Smits, P. Pauwels, M. Peeters

引用次数: 8

The Brisbane Breast Bank 布里斯班乳房银行

Open Journal of Bioresources Pub Date : 2018-02-06 DOI: 10.5334/OJB.33

A. Reed, J. Saunus, K. Ferguson, Colleen Niland, P. Simpson, S. Lakhani

引用次数: 13

The Radboud Biobank: A Central Facility for Disease-Based Biobanks to Optimise Use and Distribution of Biomaterial for Scientific Research in the Radboud University Medical Center, Nijmegen 内梅亨大学医学中心内梅亨生物库:基于疾病的生物库的中心设施，以优化生物材料的使用和分配，用于科学研究

Open Journal of Bioresources Pub Date : 2018-02-06 DOI: 10.5334/OJB.36

P. Manders, J. Lutomski, C. Smit, D. Swinkels, G. Zielhuis

{"title":"The Radboud Biobank: A Central Facility for Disease-Based Biobanks to Optimise Use and Distribution of Biomaterial for Scientific Research in the Radboud University Medical Center, Nijmegen","authors":"P. Manders, J. Lutomski, C. Smit, D. Swinkels, G. Zielhuis","doi":"10.5334/OJB.36","DOIUrl":"https://doi.org/10.5334/OJB.36","url":null,"abstract":"The Radboud Biobank offers disease-based biobanks a centralized facility to optimize the use and distribution of biomaterial for scientific research. Notably, two population biobanks are also included in this collection. All collections are professionally and sustainably maintained using high-quality and secure standardized protocols for ICT, legal-ethical aspects, sample collection, processing and storage, communication and distribution. The Radboud Biobank includes biomaterial (e.g. DNA, serum, plasma, tissue, urine and faeces – depending on the specific patient group), images, associated clinical data (patient, disease-specific and phenotypic data) and derived information (genotypic data, microarray gene expressions). Patient advocates and other relevant stakeholders are actively involved in the governance of the Radboud Biobank. Funding statement: The Radboud Biobank was implemented by the Radboudumc Executive Board as part of the university research infrastructure. It is a central facility for the Radboudumc, with guaranteed central support for at least 15 years. A governing strategic board, encompassing relevant stakeholder groups, oversees the operations of the Radboud Biobank. Two patient representatives are included in this strategic board, and one holds the position of chairperson.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":"5 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46190834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

The Tumour Bank at the Children’s Hospital at Westmead: An Australian Paediatric Cancer Biorepository Westmead儿童医院肿瘤库：澳大利亚癌症儿科生物库

Open Journal of Bioresources Pub Date : 2018-02-06 DOI: 10.5334/OJB.34

Li Zhou, A. Yuksel, O. Markovich, Natalie Gabrael, D. Catchpoole

{"title":"The Tumour Bank at the Children’s Hospital at Westmead: An Australian Paediatric Cancer Biorepository","authors":"Li Zhou, A. Yuksel, O. Markovich, Natalie Gabrael, D. Catchpoole","doi":"10.5334/OJB.34","DOIUrl":"https://doi.org/10.5334/OJB.34","url":null,"abstract":"The Tumor Bank at The Children’s Hospital at Westmead was established in 1998 with the purpose of facilitating research into childhood malignancy through the active provision of well annotated, ethically collected tissue samples and providing a pathway for the Children Hospital at Westmead to engage in leading research initiatives, supporting international investigations and clinical trials. Within 20 years practice as a single institute biorepository, The Tumour Bank has established standard operating procedures for collection of tissue, blood and bone marrow that were integrated into routine patient management systems. In addition, three main operational areas have been developed: collection of biospecimens and written consent; management of clinical data and biospecimen inventory database; and implementation of an open access policy to support childhood cancer research around the world. Regulatory oversight is provided by the Tumour Bank Committee, Human Research Ethics Committee and Governance Department. This concerted effort has resulted in collecting 20340 specimens from 3788 patients within 20 years, and The Tumour bank has supported over 108 national and international research projects, and contributed to over 70 peer-reviewed publications to date, with a mean time–to-publication of 19.1 ± 9.0 months and average Impact Factor of 6.11 ± 4.53. In conclusion, the Children’s Hospital at Westmead Tumour Bank has demonstrated a sustained single institutional biorepository model for facilitating translational research of rare cancer. It has provided strong evidence that integration of a single institutional biobank into standard clinical practices would be the long-term pathway of valuable bio-resource for rare cancer research.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43173565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amniotic Fluid Cells Biobank for Research on Fetal Mesenchymal Stem Cells 羊水细胞生物库用于胎儿间充质干细胞的研究

Open Journal of Bioresources Pub Date : 2018-02-06 DOI: 10.5334/OJB.35

Fecarotta Emanuela, S. Giovanna, Garofalo Giuseppa Maria, Damiani Gianfranca, Piazza Angela, Sacco Massimiliano, Renda Disma, G. Antonino, Cristian Catalano, M. Aurelio, Renda Maria Concetta

引用次数: 0

The UK Clinical Research Collaboration (UKCRC) Tissue Directory and Coordination Centre: The UK’s Centre for facilitating the Usage of Human Samples for Medical Research 英国临床研究合作组织（UKCRC）组织目录和协调中心：英国促进医学研究人类样本使用的中心

Open Journal of Bioresources Pub Date : 2017-05-18 DOI: 10.5334/OJB.31

P. Quinlan, E. Lawrence, Amir Pourabdolla, J. Sims, A. Gander, B. Fuller, B. Thomson, J. Garibaldi, B. Davidson

{"title":"The UK Clinical Research Collaboration (UKCRC) Tissue Directory and Coordination Centre: The UK’s Centre for facilitating the Usage of Human Samples for Medical Research","authors":"P. Quinlan, E. Lawrence, Amir Pourabdolla, J. Sims, A. Gander, B. Fuller, B. Thomson, J. Garibaldi, B. Davidson","doi":"10.5334/OJB.31","DOIUrl":"https://doi.org/10.5334/OJB.31","url":null,"abstract":"The UKCRC Tissue Directory and Coordination Centre was established to improve access to and utilisation of UK human tissue samples for medical research. The key output of the Centre is the creation of the UK’s first pan-disease Tissue Directory ( https://directory.biobankinguk.org/ ). Any researcher can search the Directory based on a series of simple key words including disease classification, age, sex, sample type, preservation details, quality indicators and datasets available. The Directory as of April 2017 contains 100 Bioresources. Researchers seeking fresh samples can also search for facilities that offer bespoke collection services. Future work of the Centre will be to explore greater standardisation of biobanking activities across the UK and to facilitate an inter-connected research infrastructure related to the use of human biosamples. Funding statement: The Centre is funded by a consortium, the UK Clinical Research Collaboration, and administered by the Medical Research Council, grant number: MR/M501748/1.","PeriodicalId":36769,"journal":{"name":"Open Journal of Bioresources","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48459874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4