Chinese Neurosurgical Journal最新文献

{"title":"Clinical characteristics and survival of glioblastoma complicated with non-central nervous system tumors.","authors":"Chen Wang,&nbsp;Di Wang,&nbsp;Changqing Pan,&nbsp;Jiazheng Zhang,&nbsp;Cheng Cheng,&nbsp;You Zhai,&nbsp;Mingchen Yu,&nbsp;Zhiliang Wang,&nbsp;Guanzhang Li,&nbsp;Wei Zhang","doi":"10.1186/s41016-022-00312-1","DOIUrl":"https://doi.org/10.1186/s41016-022-00312-1","url":null,"abstract":"<p><strong>Background: </strong>Diagnosis and treatment of patients with glioblastoma (GBM) who are also diagnosed with primary non-central nervous system (CNS) tumors remain a challenge, yet little is known about the clinical characteristics and prognosis of these patients. The data presented here compared the clinical and pathological features between glioblastoma patients with or without primary non-CNS tumors, trying to further explore this complex situation.</p><p><strong>Methods: </strong>Statistical analysis was based on the clinical and pathological data of 45 patients who were diagnosed with isocitrate dehydrogenase (IDH) wild-type glioblastoma accompanied by non-CNS tumors between January 2019 and February 2022 in Beijing Tiantan Hospital. Univariate COX proportional hazard regression model was used to determine risk factors for overall survival.</p><p><strong>Results: </strong>It turned out to be no significant difference in the overall survival (OS) of the 45 patients with IDH-wild-type GBM plus non-CNS tumors, compared with the 112 patients who were only diagnosed with IDH-wild-type GBM. However, there was a significant difference in OS of GBM patients with benign tumors compared to those with malignant tumors.</p><p><strong>Conclusions: </strong>Implications for the non-central nervous system tumors on survival of glioblastomas were not found in this research. However, glioblastomas complicated with other malignant tumors still showed worse clinical outcomes.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"43"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10449913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for early seizure after revascularization in patients with moyamoya disease.","authors":"Hongchuan Niu,&nbsp;Cunxin Tan,&nbsp;Kehan Jin,&nbsp;Ran Duan,&nbsp;Guangchao Shi,&nbsp;Rong Wang","doi":"10.1186/s41016-022-00305-0","DOIUrl":"https://doi.org/10.1186/s41016-022-00305-0","url":null,"abstract":"<p><strong>Background: </strong>To investigate the risk factors for early seizure after revascularization in patients with moyamoya disease (MMD).</p><p><strong>Methods: </strong>A total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.</p><p><strong>Results: </strong>We identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR: 1.04, 95% CI 0.998-1.086; P = 0.060) and infarct side (OR: 1.92, 95% CI 0.856-4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR: 12.89, 95% CI 4.198-39.525; P = 0.000) and preoperative cerebral infarction (OR: 4.08, 95% CI 1.267-13.119; P = 0.018) were confirmed as risk factors for early seizure.</p><p><strong>Conclusions: </strong>We believe that a history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"44"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10449915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microsurgery for vestibular schwannoma: analysis of short-term clinical outcome.","authors":"Xu Wang,&nbsp;Mingchu Li,&nbsp;Xinru Xiao,&nbsp;Ge Chen,&nbsp;Jie Tang,&nbsp;Qingtang Lin,&nbsp;Hongchuan Guo,&nbsp;Gang Song,&nbsp;Xiaolong Wu,&nbsp;Yuhai Bao,&nbsp;Jiantao Liang","doi":"10.1186/s41016-022-00306-z","DOIUrl":"https://doi.org/10.1186/s41016-022-00306-z","url":null,"abstract":"<p><strong>Background: </strong>Total removal of the vestibular schwannoma when preserving the function of the facial nerve is difficult. The objective of the current study was to investigate the short-term clinical outcome of vestibular schwannoma removal via retro-sigmoid approach.</p><p><strong>Methods: </strong>One-hundred consecutive patients diagnosed with vestibular schwannoma were surgically treated between December 2018 and August 2019 in Xuanwu Hospital, Capital Medical University. The clinical classification, surgical position, gross total removal rate, the anatomical and functional preservation rates of facial nerve, and the postoperative complications were retrospectively analyzed.</p><p><strong>Results: </strong>All 100 patients including 34 males and 66 females were operated on via retro-sigmoid approach. According to Koos vestibular schwannoma grading system, 18 cases were grade 2, 34 cases were grade 3, and 48 cases were grade 4. According to Hannover vestibular schwannoma grading system, 5 cases were T2, 6 cases were T3a, 8 cases were T3b, 30 cases were T4a, and 51 cases were T4b. Seventy-three surgeries were performed under lateral position, and 27 cases were operated under semi-sitting position. The gross total removal rate was 90.0%; the anatomic reservation rate of the facial nerve was 96.0%. According to the House-Brackman system, the facial nerve function was grades 1-2 in 78.0% cases, grade 3 in 7.0% cases, and grades 4-5 in 15% cases. For patients with effective hearing before operation, the hearing reservation rate was 19.0%. Two patients (2.0%) developed intracranial hematoma after operation.</p><p><strong>Conclusion: </strong>Most vestibular schwannoma could be completely removed with good postoperative facial nerve function. If total removal of tumor is difficult, we should give priority to the functional preservation of the nerve function.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"42"},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10768174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A falcotentorial dural arteriovenous fistula presented as carotid cavernous fistula clinically treated by transarterial embolization: case report.","authors":"Yuan Shi,&nbsp;Peixi Liu,&nbsp;Yingtao Liu,&nbsp;Kai Quan,&nbsp;Yanlong Tian,&nbsp;Wei Zhu","doi":"10.1186/s41016-022-00309-w","DOIUrl":"https://doi.org/10.1186/s41016-022-00309-w","url":null,"abstract":"<p><strong>Background: </strong>Dural arteriovenous fistulas (DAVF) represent almost 10-15% of intracranial malformations that cause intracranial hemorrhage and focal neurological deficits. Seldom tentorial DAVF cases present with ocular manifestations initially, which occur frequently in carotid-cavernous fistula (CCF) and cavernous sinus DAVF (CS DAVF).</p><p><strong>Case presentation: </strong>We report an unusual falcotentorial DAVF case draining via the superior and inferior ophthalmic veins that caused left-side increased intraocular pressure. The patient's chief complaint was swelling on the left side, pain and conjunctival congestion. He received endovascular embolization via a transarterial approach, and postoperative angiography demonstrated that the falcotentorial DAVF was occluded completely.</p><p><strong>Conclusion: </strong>Except for CCF and CS DAVF, some specific subtypes of DAVF should be considered if the patient initially presents with ocular symptoms. Differential diagnosis and definitive treatment are mandatory to avoid a delayed diagnosis and irreversible symptoms.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10353922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The risk factors of hemorrhage in stereotactic needle biopsy for brain lesions in a large cohort: 10 years of experience in a single center.","authors":"Hailong Li,&nbsp;Chunling Zheng,&nbsp;Wei Rao,&nbsp;Junzhao Sun,&nbsp;Xin Yu,&nbsp;Jianning Zhang","doi":"10.1186/s41016-022-00307-y","DOIUrl":"https://doi.org/10.1186/s41016-022-00307-y","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to identify the risk factors for hemorrhage from a large cohort who underwent stereotactic needle biopsy for brain lesions at a single center over a 10-year period.</p><p><strong>Methods: </strong>We performed a retrospective chart review of consecutive patients who underwent stereotactic biopsy at our institute between January 2010 and December 2019. Demographic characteristics and clinical variables were collected and analyzed to identify risk factors for postbiopsy hemorrhage using the chi-square test and univariable and multivariable logistic regression analyses.</p><p><strong>Results: </strong>A total of 3196 patients were included in this study; of these, a histological diagnosis was eventually made for 2938 (91.93%) patients. Hemorrhage occurred in 149 (4.66%) patients, and symptomatic hemorrhage occurred in 46 (1.44%) patients. In multivariable logistic regression analyses, the presence of deep-seated lesions (OR 1.272, p = 0.035), concomitant edema and enhancement on MR imaging scans (OR 1.827, p = 0.002), intraoperative hypertension without a past history (OR 1.012, p = 0.024), and the presence of high-grade glioma (OR 0.306, p = 0.003) were identified as independent predictors of hemorrhage after biopsy.</p><p><strong>Conclusion: </strong>Stereotactic needle biopsy is a safe and effective way to obtain tissue from brain lesions for histological diagnosis. The presence of deep-seated lesions, concomitant edema, and enhancement on MR imaging scans and the presence of high-grade glioma are independent predictors of hemorrhage after stereotactic biopsy.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"40"},"PeriodicalIF":0.0,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10321689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombospondin-2 promotes the proliferation and migration of glioma cells and contributes to the progression of glioma.","authors":"Tian-Lan Huang,&nbsp;Yi-Wen Mei,&nbsp;Yang Li,&nbsp;Xin Chen,&nbsp;Si-Xun Yu,&nbsp;Yong-Qin Kuang,&nbsp;Hai-Feng Shu","doi":"10.1186/s41016-022-00308-x","DOIUrl":"https://doi.org/10.1186/s41016-022-00308-x","url":null,"abstract":"<p><strong>Background: </strong>Gliomas, especially high-grade gliomas, are highly malignant with a poor prognosis. Although existing treatments have improved the survival rate of patients with glioma, the recurrence and mortality rates are still not ideal. The molecular mechanisms involved in the occurrence and development of glioma are still poorly understood. We previously reported that thrombospondin-2 (TSP2) expression was increased in tumor specimens from rat models, promoting excitatory synapse formation. However, little is known about the effect of TSP2 on the biological characteristics of glioma.</p><p><strong>Methods: </strong>Glioma and cerebral cortex tissues were collected from 33 patients, and the expression of TSP2 in them was analyzed. Next, the proliferation and migration of TSP2 on glioma cells were analyzed in vitro. At last, a glioma transplantation model was constructed to explore the growth of TSP2 on glioma in vivo.</p><p><strong>Results: </strong>The expression of TSP2 in surgical glioma specimens was increased compared to that in the normal cortex. Interestingly, the TSP2 protein level was higher in high-grade glioma (HGG, World Health Organization (WHO) grades 3-4) than in low-grade glioma (LGG, WHO grades 1-2) tissues. Exogenous addition of the TSP2 protein at an appropriate concentration promoted the migration of glioma cells but did not significantly affect their proliferation. Surprisingly, overexpression of TSP2 promoted both the migration and proliferation of cultured glioma cells. Moreover, in vivo experimental data implied that overexpression of TSP2 in C6 cells promoted the malignant growth of gliomas, while knockout of TSP2 slowed glioma growth.</p><p><strong>Conclusions: </strong>TSP2 promotes the migration and proliferation of glioma cells, which may provide new ideas for blocking glioma progression.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"39"},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10695641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plaque characteristics after endovascular treatment in patients with intracranial atherosclerotic disease.","authors":"Shun Zhang,&nbsp;Junjie Wang,&nbsp;Jun Lu,&nbsp;Peng Qi,&nbsp;Shen Hu,&nbsp;Ximeng Yang,&nbsp;Kunpeng Chen,&nbsp;Daming Wang","doi":"10.1186/s41016-022-00302-3","DOIUrl":"https://doi.org/10.1186/s41016-022-00302-3","url":null,"abstract":"<p><strong>Background: </strong>Endovascular treatment (EVT) is an alternative option for symptomatic intracranial atherosclerotic disease (ICAD). However, the effect of EVT treatment on ICAD plaques is still unclear. This study describes the ICAD plaque characteristics after EVT treatment and analyzes the effect of different EVT treatments on plaque characteristics.</p><p><strong>Method: </strong>From 2017 January to 2022 January, ICAD patients who underwent endovascular treatment and had follow-up high-resolution magnetic resonance image (HRMRI) were enrolled in the study. Multiple plaque characteristics, including plaque enhancement, plaque burden, were measured based on preoperative, and follow-up HRMRI. Plaque characteristics and postoperative plaque changes were analyzed between different treatment groups.</p><p><strong>Result: </strong>Finally, 50 intracranial atherosclerotic plaques in 45 patients were included. Including 28 male patients and 17 female, media age 63.0 years old. Among 50 plaques, 41 received percutaneous angioplasty (including 22 plain balloons and 19 drug-coated balloons (DCB)) and the other 9 underwent stenting. Stenosis rate, plaque burden and eccentricity index at the lesion site were significantly decreased after EVT compared with preoperative periods (p <0.001). And only the DCB group showed a significant reduction in plaque enhancement at follow-up (p < 0.001). No significant preoperative and postoperative changes in other plaque characteristics were found.</p><p><strong>Conclusion: </strong>EVT treatment could compromise the characteristics of intracranial periarterial atherosclerotic plaques, and DCB treatment may result in a reduction in plaque enhancement after treatment.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10328982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradural extramedullary cervical metastasis from Merkel cell carcinoma: a case report and literature review.","authors":"Giovanni Pennisi,&nbsp;Andrea Talacchi,&nbsp;Marcello Nunzio Tirendi,&nbsp;Marco Giordano,&nbsp;Alessandro Olivi","doi":"10.1186/s41016-022-00310-3","DOIUrl":"https://doi.org/10.1186/s41016-022-00310-3","url":null,"abstract":"<p><strong>Background: </strong>Merkel cell carcinoma (MCC) is a rare aggressive primary skin carcinoma with an incidence of 44 cases per 100,000. The natural course of MCC often results in rapid growth and early metastasis. On the other hand, the spinal cord is rarely affected and frequently features the end stage of the disease. The aim of this paper was to clarify the management of patients with spine metastasis from a skin lesion and showed a case-based update.</p><p><strong>Case presentation: </strong>A 73-year-old female was admitted to the Neurosurgical Department in December 2021 for a sudden right hemiparesis with bladder dysfunction and a history of cutaneous Merkel cell carcinoma. A magnetic resonance imaging (MRI) of the central nervous system (CNS) showed an intradural-extramedullary right-sided C6-C7 tumor with mass effect and edema of the cervical cord. The patient underwent a C6-C7 laminectomy with microsurgical total resection of the intradural extramedullary lesion. The neuropathological examination identified a metastasis from Merkel cell carcinoma. Nowadays, evidence for spinal metastasis from malignities skin cancer is generally lacking, probably because they are extremely rare. The exact time of life expectancy is controversial, and some clinicians use a cutoff of 3 months to determine whether surgical intervention should be offered, while others advocate at least 6 months of life expectancy.</p><p><strong>Conclusions: </strong>To the best of our knowledge, we showed the first case of solitary intradural extramedullary cervical spine metastasis from MCC. We recommend to consider metastasis of MCC in the differential diagnosis of spinal metastasis.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"38"},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10678682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional outcome of surgical management of low mid-grade lumbar spondylolisthesis when considering the sagittal balance parameters preoperatively: a prospective study.","authors":"Sameh Elmorsy Hassan Elmorsy,&nbsp;Hazem Abdelsattar Abulnasr,&nbsp;Yousry Hassan,&nbsp;Magdy Samra,&nbsp;Ehab Mohamed Eissa","doi":"10.1186/s41016-022-00303-2","DOIUrl":"https://doi.org/10.1186/s41016-022-00303-2","url":null,"abstract":"<p><strong>Background: </strong>Prospective study objectives. A sagittal balance is a good tool to improve the functional outcome of spine spondylolisthesis surgeries, primarily noted that it has a good impact in deformity surgery and then applied to every spine surgery and the aim of this study is to evaluate its functional outcome when considered in preoperative planning for non-dysplastic low- and mid-grade spondylolisthesis surgeries.</p><p><strong>Method: </strong>Forty patients diagnosed as low- or mid-grade non-dysplastic spondylolisthesis had undergone surgery at Cairo University after failed medical treatment had been evaluated preoperatively by measuring the sagittal balance parameters which include SVA, spinopelvic angles, lumbar lordosis, pelvic tilt, sacral slope, and pelvic incidence and then measure it along a follow-up period of 1 year postoperatively started from February 2018 and correlate it with functional outcome using Oswestry score (ODI)and VAS. Correction of parameters has been estimated preoperatively by manual estimation and Surgimap application then applied during the operation.</p><p><strong>Results: </strong>All patients were treated by surgical treatment through posterior transpedicular screw fixation with conventional or reduction screws and fusion ± TLIF cages. The mean of lumbar lordosis and mean spinopelvic angles were increased in a statistically significant manner. Pelvis tilt was decreased in a statistically insignificant manner. The mean of pelvic incidence was not changed and statistically insignificant, and this is matching the fact that pelvic incidence is a constant parameter. The sacral slope was increased in a statistically insignificant manner. Final results showed that 37 had a statistically significant improvement in their ODI >20% at the last visit. Three patients had a poor clinical outcome with ODI scorFinal results showed that 37 had a statistically significant improvement in their ODI >20% at the last visit. Three patients had a poor clinical outcome with ODI score of >20% improvement, and we noticed that the level of pathology was at the level of L4L5, SVA was positive and worsen postoperatively, and also, it is accompanied by decreased lumbar lordosis. Change in ODI means statistically significant improvement when considering sagittal parameters preoperation and during operation.</p><p><strong>Conclusion: </strong>Sagittal balance parameters should be considered in the surgical management of low-grade spondylolisthesis cases to improve their functional outcome.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10337876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic surgery versus craniotomy in the treatment of spontaneous intracerebral hematoma: a systematic review and meta-analysis.","authors":"Xiaolin Du,&nbsp;Xiaoning Lin,&nbsp;Cheng Wang,&nbsp;Kun Zhou,&nbsp;Yigong Wei,&nbsp;Xinhua Tian","doi":"10.1186/s41016-022-00304-1","DOIUrl":"https://doi.org/10.1186/s41016-022-00304-1","url":null,"abstract":"<p><strong>Background: </strong>Spontaneous intracerebral hemorrhage (SICH) has high morbidity and mortality, with no clear standard of treatment available. Compared with the craniotomy approach, neuroendoscopy is a relatively minimally invasive treatment method, and may be an efficient alternative. Therefore, this meta-analysis aimed to assess the clinical efficacy of neuroendoscopy and craniotomy in SICH patients.</p><p><strong>Methods: </strong>The electronic databases Web of Science, PubMed, EmBase, MEDLINE, and the Cochrane Library were systematically searched. According to the PRISMA template, we finally selected and analyzed 14 eligible studies that evaluated neuroendoscopy versus craniotomy. Primary outcomes included operation time, intraoperative blood loss volume, evacuation rate, residual hematoma, complications, hospital stay duration, clinical outcomes, and other parameters.</p><p><strong>Results: </strong>A total of 4 randomized controlled trials (RCTs) and 10 retrospective studies (non-RCTs) involving 1652 patients were included in the final analysis. In the neuroendoscopy (NE) group, operation time (p < 0.00001), intraoperative blood loss volume (p < 0.0001), hematoma evacuation rate (p = 0.0002), complications (p < 0.00001), hospitalization days (p = 0.004), and mortality (p < 0.0001) were significantly different from those of the craniotomy (C) group, with a higher rate of good recovery compared with the craniotomy group (P < 0.00001).</p><p><strong>Conclusions: </strong>These findings suggest that patients with SICH and physicians may benefit more from neuroendoscopic surgery than craniotomy.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"36"},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}