Hongchuan Niu, Cunxin Tan, Kehan Jin, Ran Duan, Guangchao Shi, Rong Wang
{"title":"烟雾病患者血运重建术后早期发作的危险因素。","authors":"Hongchuan Niu, Cunxin Tan, Kehan Jin, Ran Duan, Guangchao Shi, Rong Wang","doi":"10.1186/s41016-022-00305-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>To investigate the risk factors for early seizure after revascularization in patients with moyamoya disease (MMD).</p><p><strong>Methods: </strong>A total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.</p><p><strong>Results: </strong>We identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR: 1.04, 95% CI 0.998-1.086; P = 0.060) and infarct side (OR: 1.92, 95% CI 0.856-4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR: 12.89, 95% CI 4.198-39.525; P = 0.000) and preoperative cerebral infarction (OR: 4.08, 95% CI 1.267-13.119; P = 0.018) were confirmed as risk factors for early seizure.</p><p><strong>Conclusions: </strong>We believe that a history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"8 1","pages":"44"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793645/pdf/","citationCount":"0","resultStr":"{\"title\":\"Risk factors for early seizure after revascularization in patients with moyamoya disease.\",\"authors\":\"Hongchuan Niu, Cunxin Tan, Kehan Jin, Ran Duan, Guangchao Shi, Rong Wang\",\"doi\":\"10.1186/s41016-022-00305-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>To investigate the risk factors for early seizure after revascularization in patients with moyamoya disease (MMD).</p><p><strong>Methods: </strong>A total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.</p><p><strong>Results: </strong>We identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR: 1.04, 95% CI 0.998-1.086; P = 0.060) and infarct side (OR: 1.92, 95% CI 0.856-4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR: 12.89, 95% CI 4.198-39.525; P = 0.000) and preoperative cerebral infarction (OR: 4.08, 95% CI 1.267-13.119; P = 0.018) were confirmed as risk factors for early seizure.</p><p><strong>Conclusions: </strong>We believe that a history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.</p>\",\"PeriodicalId\":36700,\"journal\":{\"name\":\"Chinese Neurosurgical Journal\",\"volume\":\"8 1\",\"pages\":\"44\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793645/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Neurosurgical Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s41016-022-00305-0\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Neurosurgical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s41016-022-00305-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景:探讨烟雾病(MMD)患者血运重建后早期癫痫发作的危险因素。方法:回顾性分析2015 - 2018年我院确诊的烟雾病患者298例。我们总结了烟雾病患者血运重建后癫痫发作的特点，并分析了术后早期癫痫发作的预测因素。结果:我们确定了15例烟雾病患者，他们在血运重建术后一周内发生癫痫发作。根据logistic回归分析，年龄(OR: 1.04, 95% CI 0.998-1.086;P = 0.060)和梗死侧(OR: 1.92, 95% CI 0.856-4.290;P = 0.113)与早期癫痫发作事件无显著相关。术后梗死(OR: 12.89, 95% CI 4.198-39.525;P = 0.000)和术前脑梗死(OR: 4.08, 95% CI 1.267-13.119;P = 0.018)为早期癫痫发作的危险因素。结论:我们认为术前梗死史和新发梗死是烟雾病患者血运重建术后早期癫痫发作的独立危险因素。
Risk factors for early seizure after revascularization in patients with moyamoya disease.
Background: To investigate the risk factors for early seizure after revascularization in patients with moyamoya disease (MMD).
Methods: A total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.
Results: We identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR: 1.04, 95% CI 0.998-1.086; P = 0.060) and infarct side (OR: 1.92, 95% CI 0.856-4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR: 12.89, 95% CI 4.198-39.525; P = 0.000) and preoperative cerebral infarction (OR: 4.08, 95% CI 1.267-13.119; P = 0.018) were confirmed as risk factors for early seizure.
Conclusions: We believe that a history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
