Chinese Neurosurgical Journal最新文献

{"title":"Multiomics and blood-based biomarkers of moyamoya disease: protocol of Moyamoya Omics Atlas (MOYAOMICS).","authors":"Peicong Ge, Zihan Yin, Chuming Tao, Chaofan Zeng, Xiaofan Yu, Shixiong Lei, Junsheng Li, Yuanren Zhai, Long Ma, Qiheng He, Chenglong Liu, Wei Liu, Bojian Zhang, Zhiyao Zheng, Siqi Mou, Zhikang Zhao, Shuang Wang, Wei Sun, Min Guo, Shuai Zheng, Jia Zhang, Xiaofeng Deng, Xingju Liu, Xun Ye, Qian Zhang, Rong Wang, Yan Zhang, Shaosen Zhang, Chengjun Wang, Ziwen Yang, Nijia Zhang, Mingxing Wu, Jian Sun, Yujia Zhou, Zhiyong Shi, Yonggang Ma, Jianpo Zhou, Shaochen Yu, Jiaxi Li, Junli Lu, Faliang Gao, Wenjing Wang, Yanming Chen, Xingen Zhu, Dong Zhang, Jizong Zhao","doi":"10.1186/s41016-024-00358-3","DOIUrl":"10.1186/s41016-024-00358-3","url":null,"abstract":"<p><strong>Background: </strong>Moyamoya disease (MMD) is a rare and complex cerebrovascular disorder characterized by the progressive narrowing of the internal carotid arteries and the formation of compensatory collateral vessels. The etiology of MMD remains enigmatic, making diagnosis and management challenging. The MOYAOMICS project was initiated to investigate the molecular underpinnings of MMD and explore potential diagnostic and therapeutic strategies.</p><p><strong>Methods: </strong>The MOYAOMICS project employs a multidisciplinary approach, integrating various omics technologies, including genomics, transcriptomics, proteomics, and metabolomics, to comprehensively examine the molecular signatures associated with MMD pathogenesis. Additionally, we will investigate the potential influence of gut microbiota and brain-gut peptides on MMD development, assessing their suitability as targets for therapeutic strategies and dietary interventions. Radiomics, a specialized field in medical imaging, is utilized to analyze neuroimaging data for early detection and characterization of MMD-related brain changes. Deep learning algorithms are employed to differentiate MMD from other conditions, automating the diagnostic process. We also employ single-cellomics and mass cytometry to precisely study cellular heterogeneity in peripheral blood samples from MMD patients.</p><p><strong>Conclusions: </strong>The MOYAOMICS project represents a significant step toward comprehending MMD's molecular underpinnings. This multidisciplinary approach has the potential to revolutionize early diagnosis, patient stratification, and the development of targeted therapies for MMD. The identification of blood-based biomarkers and the integration of multiple omics data are critical for improving the clinical management of MMD and enhancing patient outcomes for this complex disease.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"10 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10851534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodality management for chronic subdural hematoma in China: protocol and characteristics of an ambidirectional, nationwide, multicenter registry study.","authors":"Tao Liu, Zhihao Zhao, Jinhao Huang, Xide Zhu, Weiliang Chen, Kun Lin, Yunhu Yu, Zhanying Li, Yibing Fan, Mingqi Liu, Meng Nie, Xuanhui Liu, Chuang Gao, Wei Quan, Yu Qian, Chenrui Wu, Jiangyuan Yuan, Di Wu, Chuanxiang Lv, Shiying Dong, Liang Mi, Yu Tian, Ye Tian, Jianning Zhang, Rongcai Jiang","doi":"10.1186/s41016-024-00356-5","DOIUrl":"10.1186/s41016-024-00356-5","url":null,"abstract":"<p><strong>Background: </strong>Despite its prevalence, there is ongoing debate regarding the optimal management strategy for chronic subdural hematoma (CSDH), reflecting the variability in clinical presentation and treatment outcomes. This ambidirectional, nationwide, multicenter registry study aims to assess the efficacy and safety of multimodality treatment approaches for CSDH in the Chinese population.</p><p><strong>Methods/design: </strong>A multicenter cohort of CSDH patients from 59 participating hospitals in mainland China was enrolled in this study. The treatment modalities encompassed a range of options and baseline demographics, clinical characteristics, radiographic findings, and surgical techniques were documented. Clinical outcomes, including hematoma resolution, recurrence rates, neurological status, and complications, were assessed at regular intervals during treatment, 3 months, 6 months, 1 year, and 2 years follow-up.</p><p><strong>Result: </strong>Between March 2022 and August 2023, a comprehensive cohort comprising 2173 individuals who met the criterion was assembled across 59 participating clinical sites. Of those patients, 81.1% were male, exhibiting an average age of 70.12 ± 14.53 years. A historical record of trauma was documented in 48.0% of cases, while headache constituted the predominant clinical presentation in 58.1% of patients. The foremost surgical modality employed was the burr hole (61.3%), with conservative management accounting for 25.6% of cases. Notably, a favorable clinical prognosis was observed in 88.9% of CSDH patients at 3 months, and the recurrence rate was found to be 2.4%.</p><p><strong>Conclusion: </strong>This registry study provides critical insights into the multimodality treatment of CSDH in China, offering a foundation for advancing clinical practices, optimizing patient management, and ultimately, improving the quality of life for individuals suffering from this challenging neurosurgical condition.</p><p><strong>Trial registration: </strong>ChiCTR2200057179.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"10 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10809648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventriculo-atrial shunt with occlusion of the internal jugular vein: operative experience and surgical technique.","authors":"Silvia Tatiana Quintero, Felipe Ramirez-Velandia, Andres Felipe Hortua Moreno, Lina Vera, Paula Rugeles, Rafael Augusto Azuero Gonzalez","doi":"10.1186/s41016-023-00354-z","DOIUrl":"10.1186/s41016-023-00354-z","url":null,"abstract":"<p><strong>Background: </strong>Ventricular shunts are one of the most frequent techniques used for the management of hydrocephalus. The ventriculoperitoneal shunt (VPS) is the most commonly performed procedure, and the ventriculoatrial shunt (VAS) is the second option in most medical centers. The main objective of this study is to introduce and describe a surgical approach for VAS outlining our experience and comparing it with traditional shunting techniques.</p><p><strong>Methods: </strong>In this retrospective cohort comparison study, we included patients with hydrocephalus treated with a surgical procedure between January 2010 and February 2021 at a single academic institution. We categorized the procedures into two groups: patients with VPS and conventional VAS grouped together into the conventional technique (CT) group, and the second group was patients with whom we performed VAS with complete internal jugular vein occlusion (IJVOT). We compared the surgical time, postoperative complications, and occurrence of shunt failure among the groups by performing univariate analysis using the Fisher exact test.</p><p><strong>Results: </strong>Out of the 106 patients included in the analysis, IJVOT was performed in 66 patients, and CT in 40 patients. The median surgical time was 60 min (IQR 60-90) for IJVOT versus 100 min (IQR 60-120) for CT (p < 0.01). In the follow-up a month after the procedure, 83.3% of patients with IJVOT and 62.5% of patients with CT did not require shunt removal or shunt revision (p < 0.01). Shunt revision rates were 12.5% and 1.5% for CT while 1.5% and 2.5% for IJVOT at 1 and 6 months after the procedure.</p><p><strong>Conclusion: </strong>Our findings demonstrate that VAS with IJVOT is a safe method that exhibited shorter surgical times and outcomes comparable to CT. However, since the present study represents the first cohort evaluating IJVOT, it is imperative to conduct larger prospective studies, along with clinical trials, to fully explore and establish efficacy, long-term outcomes, and an in-depth comparison among shunting techniques.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"10 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10785543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal dural arteriovenous fistula: a comprehensive review of the history, classification systems, management, and prognosis.","authors":"Ali Alkhaibary, Ahoud Alharbi, Nada Alnefaie, Hajar Alammar, Alshaymaa M Arishy, Noor Alghanim, Yazeed M Aldhfyan, Arwa Albaiahy, Yahya H Khormi, Wael Alshaya, Saad AlQahatani, Ahmed Aloraidi, Ahmed Alkhani, Sami Khairy","doi":"10.1186/s41016-023-00355-y","DOIUrl":"10.1186/s41016-023-00355-y","url":null,"abstract":"<p><p>Spinal dural arteriovenous fistulas account for the majority of spinal vascular malformations. They are typically located in the thoracolumbar region and are diagnosed in the middle-aged and elderly populations. Although spinal dural arteriovenous fistulas have been postulated to be acquired, their exact development remains uncertain. Typically, the arteriovenous shunt is situated close to the spinal nerve root, inside the dura mater, where the blood from the radiculomeningeal artery and radicular vein intermix. Throughout history, there have been multiple classification systems of spinal arteriovenous shunts since 1967. Those were mainly based on the evolution of diagnostic studies as well as the treatment of these lesions. Such classification systems have undergone significant changes over the years. Unlike intracranial dural arteriovenous fistula, spinal dural arteriovenous fistula is progressive in nature. The neurological manifestations, due to venous congestion, tend to be insidious as well as non-specific. These include sensory deficits, such as paresthesia, bilateral and/or unilateral radicular pain affecting the lower limbs, and gait disturbances. Spinal dural arteriovenous fistulas can be suspected on magnetic resonance imaging/magnetic resonance angiography and confirmed by digital subtraction angiography (DSA). The management includes surgery, endovascular therapy, and in selected cases, radiotherapy. The treatment goal of spinal dural arteriovenous fistula is to halt the progression of the disease. The prognosis depends on both the duration of symptoms as well as the clinical condition prior to therapy. The present article comprehensively reviews the pathophysiology, changes in classification systems, natural history, clinical manifestations, radiological features, management, and prognosis.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"10 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fully endoscopic far-lateral supracerebellar infratentorial approach for trigeminal neuralgia: illustrative case reports.","authors":"Hong Yao, Wenlei Yang, Hao Tang, Yijun Cheng, Shaojian Lin, Zhe Bao Wu","doi":"10.1186/s41016-023-00353-0","DOIUrl":"10.1186/s41016-023-00353-0","url":null,"abstract":"<p><strong>Background: </strong>Trigeminal neuralgia (TN) is a common cause of craniofacial pain. The retrosigmoid approach is usually used to treat TN, but no cases of endoscopic far-lateral supracerebellar infratentorial approach (EF-SCITA) were used to undergo operation for TN.</p><p><strong>Case presentation: </strong>Two patients were presented with severe facial pain and preliminary diagnosis was TN. Preoperative magnetic resonance imaging revealed that a superior cerebellar artery (SCA) compressed the trigeminal nerve in case 1, and a tumor located in the petrous apex extending into the Meckel's cave compressed the trigeminal nerve in case 2. Operations were achieved through the EF-SCITA. The pain was totally relieved with no postsurgical complications in both cases.</p><p><strong>Conclusions: </strong>We present the first two case reports of EF-SCITA to relieve classical and secondary TN successfully. The EF-SCITA can be a promising approach for treating TN.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"10 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10759323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification and treatment strategy for Moyamoya disease-related aneurysms.","authors":"Yangchun Hu, Xiaojian Wang, Chao Li, Liang Zhao, Jing Luo, Lei Ye, Baochun Cheng","doi":"10.1186/s41016-023-00352-1","DOIUrl":"10.1186/s41016-023-00352-1","url":null,"abstract":"<p><strong>Background: </strong>Moyamoya disease (MMD) is a cerebrovascular disorder characterized by progressive unilateral or bilateral stenosis of the distal internal carotid artery. As hemodynamic features in MMD patients alter, the comorbidity of intracranial aneurysm (IA) is sometimes observed clinically. We aim to investigate clinical characteristics and therapeutic strategies for the comorbidity of Moyamoya disease with intracranial aneurysms (MMD-IA).</p><p><strong>Methods: </strong>A total of 13 MMD-IA patients were recruited in this study and were manifested to be intracranial hemorrhage. We reviewed the surgical technique notes for all patients.</p><p><strong>Results: </strong>According to the locations of an aneurysm, MMD-IA could be divided into several categories: (1) MMD-IA at a circle of Willis-aneurysms usually located at the trunk of Willis circle; (2) MMD-IA at collateral anastomosis-aneurysms located at the distal end of collateral anastomosis; and (3) MMA-IA at basal ganglia region. In this report, aneurysms in 10 patients located at Willis circle, 2 at the pericallosal artery, and 1 at the basal ganglia region. Among them, endovascular embolism was performed among 5 patients. Aneurysm clipping was conducted among 7 patients. A patient with an aneurysm at the basal ganglia region just accepted revascularization treatment. All the treatments were successful. Follow-up studies, ranging from 6 to 24 months, demonstrated all patients received satisfactory curative effects.</p><p><strong>Conclusion: </strong>Diverse clinical presentations could be observed among MMD-IA patients. Individualized neurosurgical treatments should be chosen according to the locations of the aneurysm.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"9 1","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10731890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical, radiological, and surgical characteristics of anterior perforated substance glioma: a retrospective study.","authors":"Zhiliang Wang, Lianwang Li, Zheng Wang, Xuzhu Chen, Zhong Zhang","doi":"10.1186/s41016-023-00349-w","DOIUrl":"10.1186/s41016-023-00349-w","url":null,"abstract":"<p><strong>Background: </strong>To explore the clinical, radiological, and surgical characteristics of anterior perforated substance (APS) gliomas.</p><p><strong>Methods: </strong>Twenty patients with APS glioma who were treated with surgery between March 2019 and January 2022 from Tiantan hospital were retrospectively reviewed. The clinical, histological and radiological data were collected.</p><p><strong>Results: </strong>Twenty patients, including 7 males (55%) and 13 females (45%), with a mean age at diagnosis of 37.9 years (range, 28-53 years) underwent operative intervention for APS. Headaches and dizziness were the most common preoperative symptoms in the majority patients (14, 70%). Based on radiological features of MRI, the APS was classified into two subtypes, type A and type B. Seven patients (40%) in type A indicated a clear tumor margin, while 13 patients (60%) in type B showed an ill-defined margin. The surgical approach including frontal, temporal, and coronal frontal incisions for type A and type B tumors, respectively. Three patients in type A received total resection, while one patient in type B were total resected. Pathologically, 12 cases (60%, 12/20) were diagnosed as astrocytoma and 8 cases (20%, 8/20) were oligodendroglioma. Meanwhile, 17 cases (85%, 17/20) had MGMT promotor methylation.</p><p><strong>Conclusion: </strong>In this study, we performed the first systematic research of patients with APS glioma. Most of patients with APS presented headaches and dizziness symptoms. The APS glioma was further divided into two major radiological subtypes with relevant different surgical approaches. The APS glioma in type A were more likely to receive total resection.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"9 1","pages":"36"},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aquaporin 1 overexpression may enhance glioma tumorigenesis by interacting with the transcriptional regulation networks of Foxo4, Maz, and E2F families.","authors":"Ying Guan, Jinhua Han, Die Chen, Yuefu Zhan, Jianqiang Chen","doi":"10.1186/s41016-023-00342-3","DOIUrl":"10.1186/s41016-023-00342-3","url":null,"abstract":"<p><strong>Background: </strong>The glioblastoma has served as a valuable experimental model system for investigating the growth and invasive properties of glioblastoma. Aquaporin-1 (AQP1) in facilitating cell migration and potentially contributing to tumor progression. In this study, we analyzed the role of AQP1 overexpression in glioblastoma and elucidated the main mechanisms involved.</p><p><strong>Methods: </strong>AQP1 overexpression recombinant vector was introduced into C6 rat glioma cells to construct an AQP1 overexpression C6 cell line, and its effect on cell viability and migration ability was detected by MTT and Transwell. RNA was extracted by Trizol method for gene sequencing and transcriptomics analysis, and the differentially expressed genes (DEGs) were enriched for up- and downregulated genes by Principal component analysis (PCA), and the molecular mechanism of AQP1 overexpression was analyzed in comparison with the control group using the NCBI GEO database. Statistical analysis was performed using Mann-Whitney paired two tailed t test.</p><p><strong>Results: </strong>The cell viability of AQP1-transfected cell lines increased by 23% and the mean distance traveled increased by 67% compared with the control group. Quantitative analysis of gene expression showed that there were 12,121 genes with an average transcripts per million (TPM) value greater than 1. DEGs accounted for 13% of the genes expressed, with the highest correlation with upregulated genes being FOXO4 and MAZ, and the highest with downregulated genes being E2F TFs.</p><p><strong>Conclusions: </strong>AQP1 may be implicated in glioma formation by interacting with the transcriptional regulation networks involving the FOXO4, MAZ, and E2F1/2. These findings shed light on the potential significance of AQP1 in glioma pathogenesis and warrant further investigations to unravel the underlying molecular mechanisms.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"9 1","pages":"34"},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10698900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glibenclamide pretreatment attenuates early hematoma expansion of warfarin-associated intracerebral hemorrhage in rats by alleviating perihematomal blood–brain barrier dysfunction","authors":"Zongwei Zeng, Liang Liang, Zhou Feng, Peiwen Guo, Xiaoke Hao, Jishu Xian, Hua Feng, Yujie Chen, Zhi Chen","doi":"10.1186/s41016-023-00351-2","DOIUrl":"https://doi.org/10.1186/s41016-023-00351-2","url":null,"abstract":"","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"139 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of intraoperative neurophysiological monitoring in intramedullary spinal cord tumor surgery.","authors":"Kai Liu, Chengyuan Ma, Dapeng Li, Haisong Li, Xuechao Dong, Bo Liu, Ying Yu, Yuxiang Fan, Hongmei Song","doi":"10.1186/s41016-023-00348-x","DOIUrl":"https://doi.org/10.1186/s41016-023-00348-x","url":null,"abstract":"<p><p>Intramedullary tumors are a class of central nervous system tumors with an incidence of 2 to 4%. As they are located very deep and frequently cause postoperative neurological complications, surgical resection is difficult. In recent years, many surgeons have performed electrophysiological monitoring to effectively reduce the occurrence of postoperative neurological complications. Modern electrophysiological monitoring technology has advanced considerably, leading to the development of many monitoring methods, such as SSEPs, MEPs, DCM, and EMG, to monitor intramedullary tumors. However, electrophysiological monitoring in tumor resection is still being studied. In this article, we discussed the different monitoring methods and their role in monitoring intramedullary tumors by reviewing previous studies. Intratumorally tumors need to be monitored for a summary of the condition of the patient. Only by using various monitoring methods flexibly and through clear communication between surgeons and neurophysiological experts can good decisions be made during surgery and positive surgical results be achieved.</p>","PeriodicalId":36700,"journal":{"name":"Chinese Neurosurgical Journal","volume":"9 1","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}