IEEE Transactions on Molecular, Biological, and Multi-Scale Communications最新文献

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An Ultrasonic Power Splitting Receiver With Improved Complexity-Reliability Trade-Off for Intra-Body Communications 用于体内通信的具有改进的完整性-可靠性权衡的超声波功率分配接收器
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-09-14 DOI: 10.1109/TMBMC.2023.3315517
Yuankun Tang;Qianqian Wang;Miaowen Wen;Quansheng Guan;Fei Ji;Julian Cheng
{"title":"An Ultrasonic Power Splitting Receiver With Improved Complexity-Reliability Trade-Off for Intra-Body Communications","authors":"Yuankun Tang;Qianqian Wang;Miaowen Wen;Quansheng Guan;Fei Ji;Julian Cheng","doi":"10.1109/TMBMC.2023.3315517","DOIUrl":"10.1109/TMBMC.2023.3315517","url":null,"abstract":"Data transmission that is reliable and relies on low-complexity transceiver techniques is of practical importance for ultrasonic intra-body communications (IBCs). Considering the trade-off between reliability and computational complexity, this paper proposes an ultrasonic dynamic power splitting (UDPS) scheme. UDPS consists of statistic power splitting (SPS) and time switching (TS), where SPS splits the received signal to coherent detection (CD) and energy detection (ED) with an adjustable power splitting ratio, and TS switches between CD and ED with an adjustable power coefficient. Therefore, the proposed UDPS can exploit the reliability of CD and meanwhile benefit from the low complexity of ED. We also derive the theoretical bit-error rate (BER) of UDPS. Both theoretical and simulated results demonstrate that due to the linear noise in CD and non-linear noise in ED, the optimal power splitting ratio of SPS is 1 and the optimal power coefficient of TS is within (0, 1). More importantly, UDPS can achieve much lower complexity than CD at the cost of a slight BER loss for IBCs.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 4","pages":"483-488"},"PeriodicalIF":2.2,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135441898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Si3N4-SiO2-Based Silicon Photonics Nano-Biosensor for Molecular Communication 用于分子通信的Si3N4-SiO2基硅光子纳米生物传感器
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-31 DOI: 10.1109/TMBMC.2023.3308695
Shelma Cheeran Sajan;Anamika Singh;Prabhat Kumar Sharma;Santosh Kumar
{"title":"Si3N4-SiO2-Based Silicon Photonics Nano-Biosensor for Molecular Communication","authors":"Shelma Cheeran Sajan;Anamika Singh;Prabhat Kumar Sharma;Santosh Kumar","doi":"10.1109/TMBMC.2023.3308695","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3308695","url":null,"abstract":"In molecular communication (MC), information is conveyed between nano-scale transmitters and receivers using molecules. The environment sensing is a significant component of any MC system. The design of biological sensors thus is an important aspect for implementing MC systems. This paper presents a novel \u0000<inline-formula> <tex-math>$textit {Si}_{{3}}{N}_{{4}}$ </tex-math></inline-formula>\u0000-\u0000<inline-formula> <tex-math>$textit {SiO}_{{2}}$ </tex-math></inline-formula>\u0000 silicon photonics (SiPh) nano-biosensor for detection of cancer cells. This design utilizes a micro-ring resonator (MRR) structure and takes advantage of the distinct optical characteristics of various cancer cells and MC by leveraging the interaction between cancer cells and CD47 proteins. The proposed sensor design can be used in artificial nano-machines deployed in a MC system for the applications like cancer cell detection and targeted drug delivery.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"340-345"},"PeriodicalIF":2.2,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67982993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Network Medicine: From Conceptual Frameworks to Applications and Future Trends 网络医学:从概念框架到应用和未来趋势
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-25 DOI: 10.1109/TMBMC.2023.3308689
Enes Sefa Ayar;Sina Dadmand;Nurcan Tuncbag
{"title":"Network Medicine: From Conceptual Frameworks to Applications and Future Trends","authors":"Enes Sefa Ayar;Sina Dadmand;Nurcan Tuncbag","doi":"10.1109/TMBMC.2023.3308689","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3308689","url":null,"abstract":"The intricate nature of biological processes is orchestrated by molecular interactions. The complexity of these interactions stems from the sheer number of components involved and their relationships. To overcome this complexity, network medicine adopts a holistic, integrative approach at multiple levels. The human interactome involves over 100,000 molecules, including proteins, RNAs, and metabolites, all interconnected by a network of connections. One challenge in understanding the human interactome is associating specific parts of this network with biological phenomena such as diseases, drug resistance, and other abnormalities. Although molecular measurements can quantitatively identify many altered molecules, making sense of these molecular changes within the broader network context is a formidable task. Notably, alterations in the human interactome often occur in closely connected regions of the network. By using prior biological knowledge and applying the context-specific molecular interplays, specific sub-networks can be extracted. These network modules can provide valuable insights into complex biological questions. Furthermore, a range of learning and graph-based methodologies are employed to deduce meaningful clinical outcomes in these modules. In this context, we present a comprehensive overview of the standard workflows utilized in network medicine, along with a discussion of its applications and future directions.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"374-381"},"PeriodicalIF":2.2,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67981861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Complexity Timing Methods for Molecular Communication via Diffusion 通过扩散实现分子通信的低复杂度计时方法
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-15 DOI: 10.1109/TMBMC.2023.3305390
Umut Eren Usturalı;Bayram Cevdet Akdeniz;Tuna Tuğcu;Ali Emre Pusane
{"title":"Low-Complexity Timing Methods for Molecular Communication via Diffusion","authors":"Umut Eren Usturalı;Bayram Cevdet Akdeniz;Tuna Tuğcu;Ali Emre Pusane","doi":"10.1109/TMBMC.2023.3305390","DOIUrl":"10.1109/TMBMC.2023.3305390","url":null,"abstract":"Molecular communication is expected to be instrumental in the advancement of nanotechnology. Implementation of robust molecular communication channels that work in conjunction with other nanodevices necessitates the development of synchronization techniques for such systems. Although a number of works exist in this area, most of the proposed solutions are infeasible given the computational limitations of the components. In this paper, we propose two related methods within the framework of molecular communication via diffusion (MCvD) paradigm. These methods require only the most basic computational resources. We assess their performance analytically and computationally, indicate the error margins for each one, and discuss when one is more useful than the other.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 4","pages":"478-482"},"PeriodicalIF":2.2,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79312616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wearable Electrochemical Sensors for Healthcare Monitoring: A Review of Current Developments and Future Prospects 医疗监护用可穿戴电化学传感器的发展现状与展望
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-10 DOI: 10.1109/TMBMC.2023.3304240
Fariborz Mirlou;Levent Beker
{"title":"Wearable Electrochemical Sensors for Healthcare Monitoring: A Review of Current Developments and Future Prospects","authors":"Fariborz Mirlou;Levent Beker","doi":"10.1109/TMBMC.2023.3304240","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3304240","url":null,"abstract":"Wearable devices and biosensors have gained significant attention due to their high potential to continuously monitor the biomarkers in human body biofluids through non-invasive and minimally invasive methods and give feedback to the users in real-time. Numerous developments have been made in the electrochemical devices field for the non-invasive measurements of the desired biomarkers, including detecting different electrolytes, metabolites, and hormones. Integrating multiplexed human health monitoring, using biosensors, and transmitting the acquired data using wireless systems has been achieved and miniaturized. These systems have been combined with flexible materials to enhance their conformability and easy use. Such precise monitoring of the target biomarker and physiological data through wearable devices would significantly improve life quality by providing critical health-related information in real time. On the other hand, there needs to be an in-depth understanding of analyte concentrations in blood and their correlation to other biofluids, which will help improve the biosensors’ reliability. Thus, conducting large-scale in-vivo studies on different subjects using wearable biosensors and clinical equipment is an essential validation factor for the biosensors. Here, we focus on wearable electrochemical devices that can non-invasively measure and track the human body’s vital health information and transmit it to the users’ mobile devices.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"364-373"},"PeriodicalIF":2.2,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67981862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Molecular Robotics to Molecular Cybernetics: The First Step Toward Chemical Artificial Intelligence 从分子机器人到分子控制论:迈向化学人工智能的第一步
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-10 DOI: 10.1109/TMBMC.2023.3304243
Akinori Kuzuya;Shin-Ichiro M. Nomura;Taro Toyota;Takashi Nakakuki;Satoshi Murata
{"title":"From Molecular Robotics to Molecular Cybernetics: The First Step Toward Chemical Artificial Intelligence","authors":"Akinori Kuzuya;Shin-Ichiro M. Nomura;Taro Toyota;Takashi Nakakuki;Satoshi Murata","doi":"10.1109/TMBMC.2023.3304243","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3304243","url":null,"abstract":"“Molecular Cybernetics” is an emerging research field aiming the development of “Chemical AI”, artificial intelligence with memory and learning capabilities based on molecular communication. It is originated from “Molecular Robotics,” which studies molecular systems that comprise of the three basic elements of robots; Sensing, Planning, and Acting. Development of an Amoeba-type molecular robot (unicellular artificial cell,) motivated the construction of multicellular artificial cell systems mimicking nerve systems. The major challenges in molecular cybernetics are molecular communication over two lipid-bilayer compartments, amplification of molecular information in a compartment, and large deformation of the compartment triggered by molecular signal, etc. Recently reported molecular devices and systems that contributes to the realization of Chemical AI are overviewed.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"354-363"},"PeriodicalIF":2.2,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/iel7/6687308/10255331/10214301.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67982995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distance Estimation From a Diffusive Process: Theoretical Limits and Experimental Results 扩散过程的距离估计:理论极限和实验结果
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-08 DOI: 10.1109/TMBMC.2023.3303363
Fabio Broghammer;Siwei Zhang;Thomas Wiedemann;Peter A. Hoeher
{"title":"Distance Estimation From a Diffusive Process: Theoretical Limits and Experimental Results","authors":"Fabio Broghammer;Siwei Zhang;Thomas Wiedemann;Peter A. Hoeher","doi":"10.1109/TMBMC.2023.3303363","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3303363","url":null,"abstract":"Estimating the distance between the source of a diffusive process and a receiver has a variety of applications, ranging from gas source localization at the macro-scale to molecular communication at the micro-scale. Distance information can be extracted from features of the observed particle concentration, e.g., its peak. This paper derives the Cramér-Rao lower bound (CRB) for distance estimation given the advection-diffusion model for absorbing receivers, which is the fundamental limit of any distance estimator. Furthermore, CRBs are obtained for estimators using only information about the observed peak. A maximum-likelihood estimator using the entire signal and two estimators based on peak detection are deduced. The derived CRBs are used to study the effect of channel parameters on the estimation performance. Finally, the performance of the proposed estimators is verified by comparing the root mean squared errors with their theoretical bounds in a simulation, and preliminary experimental results are presented.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"312-317"},"PeriodicalIF":2.2,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/iel7/6687308/10255331/10210712.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67982986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectangular Concentration-Based Nanomachine Localization in Molecular Communication Networks With Unknown Emission Time 发射时间未知的分子通信网络中基于矩形浓度的纳米机器定位
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-08 DOI: 10.1109/TMBMC.2023.3302798
Ajit Kumar;Akarsh Yadav;Sudhir Kumar
{"title":"Rectangular Concentration-Based Nanomachine Localization in Molecular Communication Networks With Unknown Emission Time","authors":"Ajit Kumar;Akarsh Yadav;Sudhir Kumar","doi":"10.1109/TMBMC.2023.3302798","DOIUrl":"10.1109/TMBMC.2023.3302798","url":null,"abstract":"Localization of nanomachines is essential for optimal functionality, including optimizing transmission rates and detecting irregular cells. The sampling concentration received by the nanomachines can be used for this purpose. The localization based on received sampling concentration requires the emission time of molecules to improve the accuracy and establish synchronization among the nanomachine. In this paper, we derive the maximum likelihood estimation for localizing nanomachine in two scenarios, that is, known and unknown emission times. In contrast to the existing model, the proposed model considers a generic input (rectangular) concentration that can accommodate both non-zero emission duration and instantaneous emission, making it more practical for many applications. The model also considers multiple symbols and challenges like inter-symbol interference. Even with the rectangular input concentration, the proposed model achieves comparable individual localization performance to the impulse concentration. Additionally, the proposed model allows for joint estimation of location and emission time using correlated observations, making it a practical and generic solution for applications.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 4","pages":"472-477"},"PeriodicalIF":2.2,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79160542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of Plasmodesmata Number and Opening State on Molecular Transports in Plants 质粒数量和开放状态对植物分子转运的影响
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-04 DOI: 10.1109/TMBMC.2023.3301038
Beatrice Ruzzante;Alessandro Piscopo;Svyatoslav Salo;Maurizio Magarini;Gabriele Candiani
{"title":"The Influence of Plasmodesmata Number and Opening State on Molecular Transports in Plants","authors":"Beatrice Ruzzante;Alessandro Piscopo;Svyatoslav Salo;Maurizio Magarini;Gabriele Candiani","doi":"10.1109/TMBMC.2023.3301038","DOIUrl":"https://doi.org/10.1109/TMBMC.2023.3301038","url":null,"abstract":"Molecular Communication (MC) studies the transport of information encoded in signaling molecules. To date, its application field is mainly restrained to health-related uses. However, MC in plants has been gaining increasing interest. The primary transport route in plant cell-to-cell communication are Plasmodesmata (PDs), pore-like structures dotting the plant cell wall. PDs opening state is influenced by several environmental damaging factors (i.e., plant viruses), and plant cells try to restore homeostasis through defense mechanisms. In this letter, we seek to depict the complexity of plant-based communication, and we propose a simple model that proves the influence of the PDs number and opening state in the transport of information in plants.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 3","pages":"329-333"},"PeriodicalIF":2.2,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/iel7/6687308/10255331/10208114.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67982990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Speed Molecular Communication in Vacuum 真空中的高速分子通信
IF 2.2
IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2023-08-01 DOI: 10.1109/TMBMC.2023.3298429
Taha Sajjad;Andrew W. Eckford
{"title":"High-Speed Molecular Communication in Vacuum","authors":"Taha Sajjad;Andrew W. Eckford","doi":"10.1109/TMBMC.2023.3298429","DOIUrl":"10.1109/TMBMC.2023.3298429","url":null,"abstract":"Existing molecular communication systems, both theoretical and experimental, are characterized by low information rates. In this paper, inspired by time-of-flight mass spectrometry (TOFMS), we consider the design of a molecular communication system in which the channel is a vacuum and demonstrate that this method has the potential to increase achievable information rates by many orders of magnitude. We use modelling results from TOFMS to obtain arrival time distributions for accelerated ions and use them to analyze several species of ions, including hydrogen, nitrogen, argon, and benzene. We show that the achievable information rates can be increased using a velocity (Wien) filter, which reduces uncertainty in the velocity of the ions. Using a simplified communication model, we show that data rates well above 1 Gbit/s/molecule are achievable.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"9 4","pages":"382-390"},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135784881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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