Novel Nano-Scale Computing Unit for the IoBNT: Concept and Practical Considerations

IF 2.4 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Stefan Angerbauer;Franz Enzenhofer;Tobias Pankratz;Medina Hamidovic;Andreas Springer;Werner Haselmayr
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引用次数: 0

Abstract

The Internet of Bio-Nano Things (IoBNT) is a novel framework that has the potential to enable transformative applications in healthcare and nano-medicine. It consists of artificial or natural tiny devices, so-called Bio-Nano Things (BNTs), that can be placed in the human body to carry out specific tasks (e.g., sensing) and are connected to the Internet. However, due to their small size their computation capabilities are limited, which restricts their ability to process data and make decision directly in the human body. Thus, we address this issue and propose a novel nano-scale computing architecture that performs matrix multiplications, which is one of the most important operations in signal processing and machine learning. The computation principle is based on diffusion-based propagation between connected compartments and chemical reactions within some compartments. The weights of the matrix can be set independently through adjusting the volume of the compartments. We present a stochastic and a dynamical model of the proposed structure. The stochastic model provides an analytical solution for the input-output relation in the steady state, assuming slow reaction rates. The dynamical model provides important insights into the systems temporal dynamics. Finally, micro- and mesoscopic simulations verify the proposed approach.
用于IoBNT的新型纳米级计算单元:概念和实际考虑
生物纳米物联网(IoBNT)是一个新颖的框架,具有在医疗保健和纳米医学领域实现变革性应用的潜力。它由人造或天然的微型设备组成,即所谓的生物纳米物(BNTs),可以放置在人体内执行特定的任务(例如,传感),并连接到互联网。然而,由于体积小,它们的计算能力有限,这限制了它们直接在人体中处理数据和做出决策的能力。因此,我们解决了这个问题,并提出了一种新的纳米级计算架构,可以执行矩阵乘法,这是信号处理和机器学习中最重要的操作之一。计算原理是基于连通隔室之间的扩散传播和某些隔室内的化学反应。通过调节隔室的体积,可以独立设置矩阵的权重。我们提出了该结构的随机模型和动态模型。随机模型提供了稳态条件下,假设反应速率较慢的输入输出关系的解析解。动力学模型提供了对系统时间动力学的重要见解。最后,通过微观和介观模拟验证了所提出的方法。
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来源期刊
CiteScore
3.90
自引率
13.60%
发文量
23
期刊介绍: As a result of recent advances in MEMS/NEMS and systems biology, as well as the emergence of synthetic bacteria and lab/process-on-a-chip techniques, it is now possible to design chemical “circuits”, custom organisms, micro/nanoscale swarms of devices, and a host of other new systems. This success opens up a new frontier for interdisciplinary communications techniques using chemistry, biology, and other principles that have not been considered in the communications literature. The IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (T-MBMSC) is devoted to the principles, design, and analysis of communication systems that use physics beyond classical electromagnetism. This includes molecular, quantum, and other physical, chemical and biological techniques; as well as new communication techniques at small scales or across multiple scales (e.g., nano to micro to macro; note that strictly nanoscale systems, 1-100 nm, are outside the scope of this journal). Original research articles on one or more of the following topics are within scope: mathematical modeling, information/communication and network theoretic analysis, standardization and industrial applications, and analytical or experimental studies on communication processes or networks in biology. Contributions on related topics may also be considered for publication. Contributions from researchers outside the IEEE’s typical audience are encouraged.
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