Health Science Reports最新文献

{"title":"Percutaneous Pulmonary Valve Implantation In Native Right Ventricular Outflow Tract Using Myval™ Without Pre-Stenting","authors":"João Luiz Langer Manica,&nbsp;Raul Ivo Rossi Filho,&nbsp;Carlos Augusto Cardoso Pedra,&nbsp;Fabio Vieira Caovilla,&nbsp;Francisco Chamié,&nbsp;Carlo Benatti Pilla,&nbsp;Pablo Thomé,&nbsp;Vinicius Fraga,&nbsp;Marcelo Ribeiro,&nbsp;Germana Cerqueira Coimbra,&nbsp;João Henrique Aramayo Rossi,&nbsp;Ênio Guerios,&nbsp;João Vitor Slaviero,&nbsp;Santiago Raul Arrieta","doi":"10.1002/hsr2.70598","DOIUrl":"https://doi.org/10.1002/hsr2.70598","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Percutaneous pulmonary valve implantation was introduced two decades ago as a low-risk alternative for patients previously operated with conduits presenting RVOT dysfunction. Recently, Sapien valve was approved for use in the pulmonary position but this valve cannot be used for RVOT larger than 29 mm. Self-expanding valves can be used for large native RVOT, however, there are some cases not suitable for this technique. The advent of 30.5 and 32 mm Myval™ balloon expandable heart valves provided the possibility to treat these patients percutaneously. The objective of this study is to describe immediate results of 30.5 and 32 mm MyVal™ valves implantation in native and large RVOT without pre-stenting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seventeen patients underwent to percutaneous pulmonary valve implantation to treat large and native dysfunctional RVOT. The mean patient age was 26.2 ± 13.0 years, and the mean patient weight was 64.8 ± 14.8 kg. All patients had been previously submitted to at least one surgical procedure. The implantation was directly performed without pre-stenting in all patients. The mean basal RVOT diameter was 27.6 ± 2.1 mm. Five patients underwent to 30.5 mm and 12 patients underwent to 32 mm pulmonary valve implantation. All patients had satisfactory valve function immediately after valve implantation. The average hospital stay was 3.2 days.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In conclusion, the 30.5 and 32 mm MyVal™ valves have significant potential for treating patients with large native RVOTs, providing a safe and effective alternative to traditional surgical approaches and existing percutaneous options.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70598","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Analysis of Changes in Respiratory Pathogens During the Influenza Season Before and After the Relaxation of Non-Pharmaceutical Intervention Policies","authors":"Lin Zhang,&nbsp;Xiang Long,&nbsp;Yun-Ju Yuan,&nbsp;Su-Li Zhao","doi":"10.1002/hsr2.70618","DOIUrl":"https://doi.org/10.1002/hsr2.70618","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>The COVID-19 pandemic has profoundly impacted the transmission dynamics and epidemiology of respiratory pathogens, primarily due to non-pharmaceutical interventions (NPIs). This study aims to evaluate the effects of NPIs on the characteristics of winter respiratory pathogens.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study involved the collection of respiratory pathogen test results from all patients tested at our hospital during two distinct periods: September 2021 to May 2022 and September 2022 to May 2023. The comparison of positive rates was performed using the <i>χ</i>² test. A <i>p</i>-value less than 0.05 indicates no statistical significance. Data analysis was performed using SPSS version 22.0.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The predominant pathogen during the 2021/2022 flu seasons was identified as Inf B (1095/9309, 11.76%). Conversely, during the 2022/2023 flu seasons, Inf A emerged as the most prevalent pathogen (4040/18,770, 21.52%). Notably, the positive rates of parainfluenza virus and <i>M. pneumoniae</i> were lower in the 2022/2023 flu seasons, while the positive rate of <i>L. pneumophila</i> was higher. Furthermore, the number of positive SARS-CoV-2 cases in the 2022/2023 flu seasons increased nearly fivefold compared to the 2021/2022 flu seasons.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The findings of this study suggest that the relaxation of NPIs has a notable influence on the transmission of certain respiratory pathogens within the population. We propose the implementation of ongoing surveillance to monitor the epidemiology and evolutionary dynamics of various respiratory pathogens, particularly in situations where NPIs are no longer necessary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Platelet-Rich Plasma in Facial Lichen Planus Pigmentosus: A Prospective Pilot Study","authors":"Chanisa Kiatsurayanon,&nbsp;Pasinee Deeudomwongsa,&nbsp;Pitcharat Pituvong,&nbsp;Praneet Sajjachareonpong","doi":"10.1002/hsr2.70455","DOIUrl":"https://doi.org/10.1002/hsr2.70455","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus which most commonly affects middle-aged individuals with skin of color. Despite multiple treatment modalities available for LPP, their efficacies are unpredictable and often disappointing. In this study, we aimed to investigate the use of platelet-rich plasma (PRP) as a novel therapy for LPP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twelve patients received three sessions of intradermal PRP injection at a 2-week interval. Week 0, 2 and 4 were treatment sessions, while Week 6, 8 and 12 were follow-up visits. Mean melanin index (MI), physician global assessment (PGA) and clinical photographs were assessed at Week 0, 2, 4, 6, 8, and 12, while quartile grading scale (QGS) and patient satisfaction were evaluated at Week 2, 4, 6, 8, and 12. Adverse effects were also recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Initial mean MI was 448.19 (18.76) and declined to 409.64 (19.13) at week 12 (<i>p</i> = 0.045). Clinical improvement as evidenced by an increase in mean QGS from Week 2 to Week 12, and a reduction on average PGA score from 3.04 at baseline to 2.21 at Week 6, 2.04 at Week 8, and 2.23 at Week 12, was observed. At Week 12, 5 patients (41.67%) reported more than 50% improvement of LPP lesions.</p>\u0000 \u0000 <p>The adverse effects were minimal, consisting primarily of swelling and bruising, which resolved on their own within a few days without the need for treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We report the first pilot study utilizing PRP for LPP treatment. The pilot study indicated that PRP significantly improved facial LPP lesions with no significant side effects. Further well-designed studies with a larger sample size, longer follow-up duration and possible longer treatment times are necessary to confirm this preliminary observation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>Thai Clinical Trials Registry identification number: TCTR20230202004 (https://www.thaiclinicaltrials.org/show/TCTR20230202004) approved on 02 February 2023.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70455","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Extensive Study of Magnesium Deficiency, 25-(OH) Vitamin D3, Inflammatory Markers, and Parathyroid Hormone in Relation to Bone Mineral Density in Iraqi Osteoporosis Patients: A Cross-Sectional Study","authors":"Eman T. Ali,&nbsp;Ali N. Mohammed,&nbsp;Amer S. Khudairi,&nbsp;Ghassan M. Sulaiman,&nbsp;Hamdoon A. Mohammed,&nbsp;Ali M. Abomughayedh,&nbsp;Mosleh M. Abomughaid","doi":"10.1002/hsr2.70641","DOIUrl":"https://doi.org/10.1002/hsr2.70641","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Backgrounds and Aims</h3>\u0000 \u0000 <p>Magnesium is essential for bone development and mineralization and may influence osteoporosis progression. However, its relationship with low bone mineral density (BMD) and fracture risk is not well understood. This study aimed to identify the primary risk factors and the effect of magnesium deficiency on bone density in osteoporosis patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study involved 162 adults categorized into normal, osteopenia, and osteoporosis groups, plus 50 healthy individuals. BMD of the lumbar spine (L1–L4) and femur neck, body mass index, and T-scores were assessed via dual-energy X-ray absorptiometry, while serum magnesium, 25-(OH) Vitamin D3, inflammatory markers, and other clinical tests were measured. The results showed significant variations in BMD, T-scores, magnesium, and vitamin 25(OH)D levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Notably, osteoporosis patients exhibited a substantial decline in mean BMD along with an increase in mean T-scores. They also had significantly lower serum levels of magnesium, vitamin 25(OH)D, and calcium, compared to other groups, while parathyroid hormone levels slightly increased. Inflammatory markers were significantly elevated in osteoporosis patients. Magnesium and vitamin 25(OH)D showed an inverse relationship with T-scores and a direct positive correlation with BMD and bone mineral content. Additionally, a negative correlation between magnesium and inflammatory markers was observed. The findings highlighted a strong correlation between magnesium deficiency and osteoporosis, with a more significant odds ratio compared to factors like 25(OH)D, PTH, BMD, T-score, and calcium.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Magnesium deficiency has a more pronounced impact on bone health than vitamin D deficiency. Thus, magnesium deficiency emerges as a major risk factor for osteoporosis progression and a predictor of fracture incidence in patients with osteoporosis or osteopenia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70641","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polypharmacy and Potentially Inappropriate Medication in Iranian People With Metabolic Syndrome: Epidemiological Aspects and Related Factors, a Multi-Level Cross-Sectional National Study","authors":"Mojdeh Daneshmand,&nbsp;Hamidreza Jamshidi,&nbsp;Mohammad-Reza Malekpour,&nbsp;Erfan Ghasemi,&nbsp;Sahar Saeedi Moghaddam,&nbsp;Seyede Salehe Mortazavi,&nbsp;Mohsen Shati,&nbsp;Mohammad Hadi Farjoo,&nbsp;Farshad Farzadfar","doi":"10.1002/hsr2.70600","DOIUrl":"https://doi.org/10.1002/hsr2.70600","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Polypharmacy, characterized by the concurrent use of five or more medications in a prescription, potentially resulting in adverse outcomes, is frequently observed among individuals with metabolic syndrome, which encompasses a collection of conditions that co-occur, heightening the likelihood of heart disease, stroke, and type 2 diabetes. This study seeks to ascertain the prevalence of polypharmacy and the use of potentially inappropriate medications (PIMs) among Iranian patients with metabolic syndrome, while also evaluating the contributing individual and sociodemographic factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a population-based, cross-sectional national study. Two databases were used: (a) Iranians Health Insurance Service database and (b) Iran's STEPS 2016 survey. Patients with metabolic syndrome conjoint in both databases were selected. Among these patients, polypharmacy and PIM were evaluated, and their association with individual and sociodemographic factors was assessed. Univariate and multivariate logistic regression were used to analyze the associations. All statistical analyses were done using SPSS 22 and Python 3.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 2075 metabolic syndrome patients, 10.3% had polypharmacy. Polypharmacy significantly increased by age (OR: 4.334, adjusted for &gt; 80-year-olds vs. 25–39-year-olds [CI: 1.664–11.283], <i>p</i> &lt; 0.001), and its prevalence was significantly higher in urban areas (OR: 2.326 [CI: 1.645–3.288], <i>p</i> &lt; 0.001). Polypharmacy was 5.88% in West, 5.41% in Southeast, 5.04% in Central, and 4.83% in North-Northeast of Iran. PIM was 13.2% in ≥ 60 years and significantly higher in urban areas (OR: 2.014 [CI: 1.153–3.519], <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Since the area of residency affects polypharmacy and PIM more significantly than wealth status and education level, it is important to implement preventive measures in urban areas.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70600","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proliferative Markers in Breast Cancer and Chemotherapy Implications: A Comprehensive Review","authors":"Aryan Salahi-Niri,&nbsp;Paniz Zarand,&nbsp;Fatemeh Shojaeian,&nbsp;Negar Mansouri,&nbsp;Omid Yazdani,&nbsp;Romina Esbati,&nbsp;Seyed Amir Ahmad Safavi-Naini,&nbsp;Behnaz Jahanbin","doi":"10.1002/hsr2.70626","DOIUrl":"https://doi.org/10.1002/hsr2.70626","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Breast cancer is the most common cancer and a leading cause of cancer-related death among women globally. Determining which patients will benefit from chemotherapy remains challenging. Proliferative markers such as Ki-67, mini chromosome maintenance (MCM) proteins, and proliferating cell nuclear antigen (PCNA) offer valuable insights into tumor growth and treatment response. This review evaluates their clinical roles, with a focus on chemotherapy implications and emerging digital pathology techniques for marker quantification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A narrative review was conducted by searching PubMed, Scopus, and Google Scholar for studies related to Ki-67, MCM, PCNA, breast cancer, and chemotherapy. Studies were thematically categorized into five areas. A bibliometric analysis of publications from 2000 to April 2023 was performed using the Bibliometrix R package and VOSviewer to assess research trends and thematic evolution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eighty studies were included in the narrative synthesis. Ki-67 is the most commonly used marker, particularly useful in predicting response to neoadjuvant chemotherapy (NAC). MCM proteins show promise for identifying proliferative potential across tumor grades, while PCNA is associated with aggressive tumor features and poor prognosis. Post-chemotherapy changes in Ki-67 levels are linked to survival outcomes. Bibliometric analysis revealed a shift in research focus from basic mechanisms to clinical applications and digital quantification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Proliferative markers play an essential role in breast cancer management. Ki-67 remains a key predictor of chemotherapy response, while MCM and PCNA offer complementary prognostic insights. Integration of these markers with digital pathology and AI-driven tools may enhance diagnostic accuracy and personalized treatment strategies. Standardization of assessment methods is crucial for broader clinical application.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70626","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda for Managing Noncommunicable Diseases in Organisation for Economic Cooperation and Development Nations: A Qualitative Systematic Review","authors":"Patricia Egwumba,&nbsp;Haiquan Wang,&nbsp;Laura Nellums,&nbsp;Manpreet Bains,&nbsp;Kaushik Chattopadhyay","doi":"10.1002/hsr2.70624","DOIUrl":"https://doi.org/10.1002/hsr2.70624","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Ayurveda, a traditional system of medicine, has gained recognition in the Organisation for Economic Cooperation and Development (OECD) countries as a complementary and alternative medicine for managing noncommunicable diseases (NCDs). Qualitative studies have been conducted in various OECD countries regarding the use of Ayurveda for NCD management. However, no qualitative systematic review has been conducted on this topic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This review aimed to synthesize the experiences, perceptions, and perspectives of patients with NCDs and Ayurvedic practitioners on the use of Ayurveda for NCD management in OECD countries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The JBI qualitative systematic review guidelines were followed. Several databases were searched to identify published and unpublished qualitative studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 18,541 records identified, 9 studies met the eligibility criteria and were included in the review. Using the JBI checklist for qualitative research (10 criteria), the critical appraisal scores of the studies ranged from moderate to high quality. Patients turned to Ayurveda because of concerns about side effects and dissatisfaction with conventional Western treatments and were driven by the perceived gentleness and holistic qualities of Ayurveda. Complementing these patient insights, Ayurvedic practitioners emphasized that Ayurveda identifies and addresses the root causes of diseases rather than treating symptoms alone. Integration challenges, limited medication access, and regulatory constraints were identified as factors affecting Ayurveda's service delivery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Patients preferred Ayurveda because of its natural approach and fewer side effects, whereas Ayurvedic practitioners valued its holistic approach. However, its wider acceptance has been hampered by hurdles such as regulatory barriers and limited access to medicines. Strategies to overcome some of the barriers identified in this review as well as to promote the strengths discussed in this review may facilitate the effective use of Ayurveda to manage NCDs in OECD countries.</p>\u0000 \u0000 <p><b>Trial Registration:</b> PROSPERO, Registration No. CRD42023397952.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70624","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Reciting the Quran on the Anxiety of Neurosurgery Muslim Candidates","authors":"Nader Salari,&nbsp;Reza Fayzi,&nbsp;Elahe Abdipuor,&nbsp;Hooman Ghasemi,&nbsp;Shamarina Shohaimi,&nbsp;Masoud Mohammadi","doi":"10.1002/hsr2.70629","DOIUrl":"https://doi.org/10.1002/hsr2.70629","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Anxiety is very common among patients undergoing surgery. Like other forms of surgery, neurosurgery can affect patients both physically and emotionally. One of the ways to control and reduce anxiety is to pay attention to spiritual interventions and spiritual health. The present study aimed to investigate the effect of the Qur'an on the anxiety of neurosurgery Muslim candidates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study is interventional research with a pretest and posttest design with a control group. The research population included all patients who were candidates for brain and nerve surgery in the teaching-treatment hospitals in 2019. The samples were selected by probability and simple random sampling methods. The data collection tool included the Spielberger questionnaire and demographics (age, gender, marital status, education degree, job, etc.) and the vital signs checklist (blood pressure, heart rate, and respiration).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The results of this study showed that the sound of the Quran leads to a decrease in the level of anxiety in the experimental group. The effect size of the group for overt anxiety and anxiety subscales is 53.5% and 40%, respectively; blood pressure is 4.3%, breathing is 20.9%, and heart rate is 21.5%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Anxiety is an unpleasant complication that many people suffer from before various surgeries. The results of this study indicated that the sound of the Quran is a positive and effective factor in reducing anxiety before neurosurgery in Muslim patients who are candidates for this surgery, so health policymakers can use the results of this study as a research priority to reduce anxiety before surgery.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Low-Cost Alternative Technique for Eye Protection During Prone Positioning in Spinal Surgery","authors":"John Emelifeonwu,&nbsp;Douglas Duncan,&nbsp;Jay J. Park,&nbsp;Andreas K. Demetriades","doi":"10.1002/hsr2.70601","DOIUrl":"https://doi.org/10.1002/hsr2.70601","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Although rare, anaesthetising patinets in prone position for spinal surgery carries a risk of serious complications. Among these, postoperative visual loss (POVL) is of significant concern. Preventing POVL requires close collaboration between spinal surgeons and anaesthetists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In our centre, we practiced a cost-effective method to ensure proper patient positioning, eye protection, and consistent assessment of eye position during prone spinal surgery. An affordable telescopic inspection mirror was used in conjunction with standard protective eye padding secured with sleek tape. This approach facilitated regular intraoperative eye checks without disrupting the surgical workflow.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The proposed approach offers an affordable and practical alternative to expensive commercial headrest options while maintaining effectiveness in reducing the risk of POVL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The method provides a viable, low-cost solution for mitigating POVL risk in prone-anaesthetised spinal surgery patients, highlighting the importance of interdisciplinary coordination and continuous monitoring.</p>\u0000 </section>\u0000 </div>","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monkeypox: Prevention Strategies and Challenges: Updated Review","authors":"Abate Wondesen Tsige,&nbsp;Siraye Genzeb Ayele","doi":"10.1002/hsr2.70640","DOIUrl":"https://doi.org/10.1002/hsr2.70640","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background and Aims&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The mpox virus, sometimes known as MPXV, is the cause of the disease mpox. The Monkeypox virus is a different Poxviridae family member from the orthopoxvirus (OPXV) group. Clades I and II are the two varieties of the Monkeypox virus. The mpox can spread from person to person through direct contact with infectious skin or other lesions, such as those on the mouth or genitalia. The mpox virus is spread from animal to people by bites or scratches, as well as through tasks including skinning, trapping, cooking, playing with carcasses, and eating animals. People with compromised immune systems, small children, those with a history of eczema, and pregnant women may be more susceptible to serious mpox illness. This review aimed to identify the challenges of mpox, treatment alternatives, and prevention modalities.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This review addressed mpox virus etiology, epidemiology, risk factors, clinical presentations, clinical evaluation techniques, currently available treatments, and preventative measures. An analysis of the narrative data was conducted instead of a pooled analysis. Complete data published in English was included in a comprehensive literature search conducted across relevant databases pertaining to the mpox.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The recommended laboratory test for mpox is polymerase chain reaction detection of viral DNA. It is crucial to differentiate measles, scabies, herpes, syphilis, chickenpox, measles, bacterial skin infections, and allergies related to medications from mpox. The ability to distinguish between chickenpox and mpox is made by lymphadenopathy. The JYNNEOS vaccine, ACAM2000 vaccine, and MVABN also known as Imvamune vaccinations have now been investigated and authorized for usage during mpox epidemics in different locations. Tecovirimat, brincidofovir, and cidofovir which had previously shown promise against OPXV were used as antivirals during the 2022 outbreak.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This review provides a brief overview of current vaccinations and antiviral medications that have been assessed for their potential as treatments since the mpox threat came into existence will be provided. It is useful to increase awareness and recognize the common clinical manifestations of mpox, diagnose, and its prevention methods. To effectively reduce the global transmission of mpox, the WHO should prioritize strategies that enhance early detection of the illness, careful administration of antiviral trea","PeriodicalId":36518,"journal":{"name":"Health Science Reports","volume":"8 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.70640","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}