EJVES Vascular Forum最新文献

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Anastomotic Pseudoaneurysm in an Abandoned Brachiocephalic Arteriovenous Fistula 吻合假性动脉瘤一例放弃的头臂动静脉瘘
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2024.12.002
Arianna Serra , Elisabetta Tanda
{"title":"Anastomotic Pseudoaneurysm in an Abandoned Brachiocephalic Arteriovenous Fistula","authors":"Arianna Serra , Elisabetta Tanda","doi":"10.1016/j.ejvsvf.2024.12.002","DOIUrl":"10.1016/j.ejvsvf.2024.12.002","url":null,"abstract":"","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Page 20"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143288554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender and Geographical Diversity in Authorship, Peer Reviewing, and Editorial Roles in the European Journal of Vascular and Endovascular Surgery Vascular Forum 《欧洲血管与血管内外科杂志》作者、同行评议和编辑角色的性别和地域差异
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2024.12.003
Melina Vega de Céniga , June Fernández
{"title":"Gender and Geographical Diversity in Authorship, Peer Reviewing, and Editorial Roles in the European Journal of Vascular and Endovascular Surgery Vascular Forum","authors":"Melina Vega de Céniga ,&nbsp;June Fernández","doi":"10.1016/j.ejvsvf.2024.12.003","DOIUrl":"10.1016/j.ejvsvf.2024.12.003","url":null,"abstract":"<div><h3>Objective</h3><div>Gender based disparities have been reported regarding principal investigator positions, authorship of medical published literature, reviewing roles, and representation in journal editorial boards. This study aimed to analyse gender and geographical differences in the authorship and editorial roles of the <em>European Journal of Vascular and Endovascular Surgery Vascular Forum</em> (EJVES VF).</div></div><div><h3>Methods</h3><div>An observational retrospective study was performed of all consecutive submissions to EJVES VF between 2020 – 2023. Data were gathered on: first author's gender, first author's professional country, last author's gender, number of authors per submission, article type, and final editorial decision. Gender and professional country of external reviewers and editorial staff were also analysed, as well as performance indicators. The statistical analysis was descriptive and chi squared and <em>t</em> tests were used.</div></div><div><h3>Results</h3><div>A total of 577 submitted papers were included. First authors were female (FFA) in 26.7% and 28.5% of submitted and accepted papers, and last authors (FLA) in 16.5% and 22%, respectively. The acceptance rate was 34.7% (<em>n</em> = 200), which was similar for FFA and male first authors (37% <em>vs</em>. 33.8%; <em>p</em> = .47). The FLA had a higher acceptance rate than male last authors (46.3% <em>vs</em>. 32.4%; <em>p</em> = 0.009). The acceptance rate of original research and review papers was 34.7% (<em>n =</em> 42), 28.2% (<em>n =</em> 101) for case reports, short reports, editorials, and surgical videos, and 52.2% for images, correspondence, and invited commentaries (<em>p</em> &lt; .001). The highest acceptance rate was achieved by Europe (<em>n =</em> 334; 43.1%), followed by America (<em>n =</em> 68; 33.8%) and Australasia (<em>n =</em> 20; 30%) (<em>p</em> &lt; .001). The journal had six female and ten male editors. The proportion of female reviewers rose from 12.4% in 2020 to 17% in 2023, and female editorial board members from 7% to 21%. Performance indicators were statistically similar for male and female reviewers.</div></div><div><h3>Conclusion</h3><div>Female authorship is under represented in submitted and published papers in EJVES VF, with important geographical differences. The number and percentage of female reviewers is increasing; their performance is comparable with their male colleagues.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Pages 45-51"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular Management of Upper Limb Arterial Aneurysms in a Child With Kawasaki Disease 川崎病患儿上肢动脉瘤的血管内治疗
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.04.005
Marian D. Moreno-Urías , Javier E. Anaya-Ayala , Alejandro Celis-Jiménez
{"title":"Endovascular Management of Upper Limb Arterial Aneurysms in a Child With Kawasaki Disease","authors":"Marian D. Moreno-Urías ,&nbsp;Javier E. Anaya-Ayala ,&nbsp;Alejandro Celis-Jiménez","doi":"10.1016/j.ejvsvf.2025.04.005","DOIUrl":"10.1016/j.ejvsvf.2025.04.005","url":null,"abstract":"<div><h3>Background</h3><div>Kawasaki disease is an acute, self limited vasculitis that predominantly affects children under five years of age. It is clinically diagnosed by persistent fever for at least five days along with four of the main clinical features. Bilateral upper limb aneurysms are rare in Kawasaki disease, with limited literature comprising case reports and small series, leaving management guidelines unclear.</div></div><div><h3>Report</h3><div>This study presents the case of a three year old male with a history of incomplete Kawasaki disease at eight months of age. Initial treatment included two doses of gammaglobulin after which he was diagnosed with aneurysms in both the left and right coronary arteries; he remained in a stable condition under bi-annual monitoring. Six months later, the patient was referred having developed aneurysms in the left axillary and right brachial arteries. Open and endovascular approaches were discussed with his parents; endovascular management was opted for. Covered stents (6 x 56 mm and 8 x 56 mm Fluency Plus Endovascular Stent Graft, Becton Dickinson &amp; Co., New Jersey, USA) were successfully placed in the left axillary and right brachial arteries during a single procedure. The patient remained haemodynamically stable and was discharged 24 hours post-operation without complications. At the 24 month follow up, the patient was asymptomatic, and ultrasound confirmed the continued patency of the stents.</div></div><div><h3>Conclusion</h3><div>This case highlights the importance of individualised treatment strategies for paediatric patients with Kawasaki disease complicated by arterial aneurysms. The use of stent grafts in children presents unique challenges, including long-term durability, vessel growth, and thrombosis risk, necessitating careful patient selection and lifelong follow up. The successful outcome observed in this case highlights the potential of endovascular techniques as a viable alternative to open surgery, emphasising the need for further studies to establish standardised guidelines for paediatric vascular interventions.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"64 ","pages":"Pages 16-19"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iatrogenic Thoracic Aortic Injury Due to Right Intercostal Drain Insertion 右肋间引流插入致医源性胸主动脉损伤
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.03.002
Giulia Bertagna, Nicola Troisi
{"title":"Iatrogenic Thoracic Aortic Injury Due to Right Intercostal Drain Insertion","authors":"Giulia Bertagna,&nbsp;Nicola Troisi","doi":"10.1016/j.ejvsvf.2025.03.002","DOIUrl":"10.1016/j.ejvsvf.2025.03.002","url":null,"abstract":"","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Page 68"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143828802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maintenance of Functionality Without Flushing of Totally Implantable Venous Access Devices: A Presentation of Clinical Cases 不冲洗全植入式静脉通路装置的功能维持:临床病例报告
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.05.005
Martina Rapisarda , Luisa Gallo , Alessandro Terrasi , Ivan Lo Iacona , Isidoro Di Carlo , Adriana Toro
{"title":"Maintenance of Functionality Without Flushing of Totally Implantable Venous Access Devices: A Presentation of Clinical Cases","authors":"Martina Rapisarda ,&nbsp;Luisa Gallo ,&nbsp;Alessandro Terrasi ,&nbsp;Ivan Lo Iacona ,&nbsp;Isidoro Di Carlo ,&nbsp;Adriana Toro","doi":"10.1016/j.ejvsvf.2025.05.005","DOIUrl":"10.1016/j.ejvsvf.2025.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of this study was to report experience of treating patients who underwent implantation of a long term totally implantable venous access device (TIVAD) that was not flushed.</div></div><div><h3>Methods</h3><div>Patients who underwent TIVAD implantation between 1995 and 2016 were included in the present study. Sex, age, type of disease, indications, surgeon, device used, choice of venous access, type of procedure, morbidity, and follow up duration were considered.</div></div><div><h3>Results</h3><div>Five hundred and forty-four patients underwent surgical TIVAD implantation. The most common type of disease was solid tumours (508 patients, 93,4%). In 503 patients, the TIVAD was implanted in the cephalic vein. Seven (1.3%) patients were diagnosed with tumour recurrence by an oncologist (5/7 male, median age 57 years). Four (57.1%) patients had recurrent colorectal cancer, and three (42.9%) had recurrent breast cancer. For several months, these patients did not return to the hospital for port flushing. None of these devices were heparinised for 18–24 months; however, no signs of occlusion were detected.</div></div><div><h3>Conclusion</h3><div>This study shows that TIVAD can remain patent without flushing. Moreover, the lack of flushing could be economically advantageous and could provide relief for patients. Therefore, a larger study of this topic is needed.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"64 ","pages":"Pages 24-27"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Waves Across the Coral Reef Aorta: Intravascular Lithotripsy in Juxtarenal Aortic Occlusive Disease 波浪穿过珊瑚礁主动脉:血管内碎石术治疗肾旁主动脉闭塞性疾病
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.04.003
Nicola Troisi, Sofia Pierozzi, Raffaella Berchiolli
{"title":"Waves Across the Coral Reef Aorta: Intravascular Lithotripsy in Juxtarenal Aortic Occlusive Disease","authors":"Nicola Troisi,&nbsp;Sofia Pierozzi,&nbsp;Raffaella Berchiolli","doi":"10.1016/j.ejvsvf.2025.04.003","DOIUrl":"10.1016/j.ejvsvf.2025.04.003","url":null,"abstract":"<div><h3>Background</h3><div>Coral reef aorta (CRA) is a rare disease characterised by rock hard intraluminal calcifications primarily localised to the visceral and juxtarenal aorta, which can cause significant stenoses, leading to visceral, renal, and lower limb ischaemia. Intravascular lithotripsy (IVL) is an innovative and promising endovascular tool for the treatment of high grade calcified stenoses.</div></div><div><h3>Report</h3><div>A 73 year old woman presented with bilateral Rutherford class 5 chronic limb threatening ischaemia and an ankle brachial pressure index (ABPI) of 0.4 right and 0.5 left. The patient had undergone kissing iliac stenting for lifestyle limiting intermittent claudication 20 years before at another centre. Computed tomography angiography showed proximal extension of the aorto-iliac occlusive disease with near occlusive CRA in the juxtarenal aorta, and patent iliac and lower limb arteries. The patient was treated with kissing balloon IVL (two 7 x 60 mm Shockwave M5 catheters; Shockwave Medical Inc, Santa Clara, CA, USA) through bilateral percutaneous femoral access, and concomitant inflation of two 4 mm balloons to protect both renal arteries through surgical left axillary access. Patency of the aorta and iliac stents was obtained with palpable femoral and peripheral pulses. No intraprocedural complication occurred. At the six month follow up, the lesions had healed, and the patient was alive with improvement in four Rutherford classes (ABPI 0.9 for both limbs).</div></div><div><h3>Conclusion</h3><div>Intravascular lithotripsy without any adjunctive iliac stenting could be a safe and effective therapeutic option in patients with juxtarenal CRA.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"64 ","pages":"Pages 28-31"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open Aortic Repair After Thoracic Endovascular Aortic Repair: Strategic Insights From a Single Centre Surgical Experience 胸腔血管内主动脉修复后的开放主动脉修复:从单中心手术经验的战略见解
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2024.12.001
Yutaka Iba, Tomohiro Nakajima, Junji Nakazawa, Tsuyoshi Shibata, Shuhei Miura, Nobuyoshi Kawaharada
{"title":"Open Aortic Repair After Thoracic Endovascular Aortic Repair: Strategic Insights From a Single Centre Surgical Experience","authors":"Yutaka Iba,&nbsp;Tomohiro Nakajima,&nbsp;Junji Nakazawa,&nbsp;Tsuyoshi Shibata,&nbsp;Shuhei Miura,&nbsp;Nobuyoshi Kawaharada","doi":"10.1016/j.ejvsvf.2024.12.001","DOIUrl":"10.1016/j.ejvsvf.2024.12.001","url":null,"abstract":"<div><h3>Objective</h3><div>Thoracic endovascular aortic repair (TEVAR) is widely used in thoracic aortic surgery. However, for various reasons some patients require secondary open aortic repair. Herein, the surgical outcomes and problems of such open conversion surgery after TEVAR are investigated.</div></div><div><h3>Methods</h3><div>This was a retrospective and observational study. From January 2010 to June 2022, 20 patients who underwent open aortic repair after TEVAR were included. The indications for open conversion surgery were as follows: aortic enlargement due to endoleak (EL) in seven patients (type Ia: <em>n</em> = 4, type II: <em>n</em> = 1, type V: <em>n</em> = 2; 35%), stent graft infection including aorto-oesophageal fistula (AEF) in six (30%), retrograde type A aortic dissection (RTAD) in three (15%), and dilatation of adjacent distal aorta or false lumen in four (20%).</div></div><div><h3>Results</h3><div>Seven patients with type Ia EL or RTAD required open aortic arch repair. Four underwent thoraco-abdominal aortic repair for distal aortic enlargement. Descending thoracic aortic replacement was performed in all six infection cases and two patients with type V EL. Furthermore, three patients with AEF received concomitant oesophagectomy. One patient with persistent type II EL underwent intercostal artery ligation and aneurysmorrhaphy via thoracotomy. There were two in hospital deaths (10%), all with AEF. Thus, the rates of in hospital death were 0% in non-infected cases, 33% in graft infections, with 66% in those with AEF. Stroke and paraplegia were observed in two patients (10%).</div></div><div><h3>Conclusion</h3><div>When open conversion surgery is required after TEVAR, the indications are complex, often associated with infectious pathology, and are necessarily high risk particularly in patients with AEF. Surgical strategy has to be individualised based on the nature or cause of the complication and extent of aortic involvement.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Pages 32-40"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When and How to Perform Open Aortic Repair After Thoracic Endovascular Repair Complications? 胸血管内修复并发症后何时及如何进行主动脉切开修复?
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.01.004
Paulo Eduardo Ocke Reis , Arindam Chaudhuri
{"title":"When and How to Perform Open Aortic Repair After Thoracic Endovascular Repair Complications?","authors":"Paulo Eduardo Ocke Reis ,&nbsp;Arindam Chaudhuri","doi":"10.1016/j.ejvsvf.2025.01.004","DOIUrl":"10.1016/j.ejvsvf.2025.01.004","url":null,"abstract":"","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Pages 30-31"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proximal Relining with Custom Made Double Branch Aortic Arch Graft to treat a type Ia Endoleak after Zone 2 Branched TEVAR 定制双支主动脉弓近端修补治疗2区支化TEVAR术后Ia型腔隙
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2025.04.004
Simona Sica , Jonathan Sobocinski
{"title":"Proximal Relining with Custom Made Double Branch Aortic Arch Graft to treat a type Ia Endoleak after Zone 2 Branched TEVAR","authors":"Simona Sica ,&nbsp;Jonathan Sobocinski","doi":"10.1016/j.ejvsvf.2025.04.004","DOIUrl":"10.1016/j.ejvsvf.2025.04.004","url":null,"abstract":"<div><h3>Objective</h3><div>Thoracic endovascular aortic repair (TEVAR) including a branch or fenestration offers a less invasive alternative to open surgery in the treatment of aortic arch pathologies. Nevertheless, the occurrence of a proximal type I endoleak (EL) in this specific setting may be particularly challenging to fix. This study presents the case of a type Ia endoleak after a zone 2 single branched TEVAR that was successfully treated with a proximal endovascular relining using a custom made double branch aortic arch graft.</div></div><div><h3>Case</h3><div>A 74 year old male presented with a 70 mm thoracic aortic aneurysm and a type Ia EL 7 years after a zone 2 TEVAR including a retrograde left subclavian artery branch. After multidisciplinary discussion, the patient underwent a hybrid repair with left carotid subclavian bypass and a custom made double branch aortic arch graft to extend proximal sealing into zone 0. The device that was used featured two antegrade inner branches for the brachiocephalic trunk and left common carotid artery. Post-operatively, the patient recovered well without neurological deficit. Follow-up imaging at three months confirmed patency of the supra-aortic trunks and favourable aortic remodelling without any residual endoleak.</div></div><div><h3>Conclusion</h3><div>This case suggests that proximal endovascular relining in zone 0 with a custom made double branch aortic arch for treating type Ia endoleak following left subclavian artery branch endograft is feasible and effective in experienced aortic centres.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"64 ","pages":"Pages 20-23"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between the Effectiveness and Magnitude of Foot Microcirculation Assessed by Radionuclide Angiography and One Year Limb Outcomes in Patients with Chronic Limb Threatening Ischaemia 放射性核素血管造影评估的慢性肢体威胁性缺血患者足部微循环的有效性和强度与一年肢体预后之间的关系
IF 1.4
EJVES Vascular Forum Pub Date : 2025-01-01 DOI: 10.1016/j.ejvsvf.2024.11.002
Takuya Hashimoto , Yoshitaka Kumakura , Kenichi Ichikawa , Satoshi Yamamoto , Takashi Endo , Masaya Sano , Osamu Sato , Juno Deguchi
{"title":"Association Between the Effectiveness and Magnitude of Foot Microcirculation Assessed by Radionuclide Angiography and One Year Limb Outcomes in Patients with Chronic Limb Threatening Ischaemia","authors":"Takuya Hashimoto ,&nbsp;Yoshitaka Kumakura ,&nbsp;Kenichi Ichikawa ,&nbsp;Satoshi Yamamoto ,&nbsp;Takashi Endo ,&nbsp;Masaya Sano ,&nbsp;Osamu Sato ,&nbsp;Juno Deguchi","doi":"10.1016/j.ejvsvf.2024.11.002","DOIUrl":"10.1016/j.ejvsvf.2024.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>Microcirculation focused evaluations may provide physiological insights that complement those of the established clinical criteria for patients with chronic limb threatening ischaemia (CLTI), since complex treatments are needed in this high risk population. However, current methods for quantitatively assessing foot microcirculation are limited. Thus, in this study, the aim was to demonstrate a proof of concept non-invasive method with novel parameters for assessing foot microcirculation.</div></div><div><h3>Methods</h3><div>This was a single centre prospective cohort pilot study. The lower limbs of 13 patients diagnosed with CLTI were evaluated by radionuclide (RN) angiography with <sup>99m</sup>Tc-tetrofosmin two weeks after revascularisation or non-revascularisation procedures. Novel parameters (pedal transit time and peak pedal count) were derived by processing the time–activity curves of the detected tracers in each region of interest in the limbs. The Mann–Whitney <em>U</em> test was used for the analysis of associations between these two parameters and limb fate at one year, and Pearson and Spearman tests were used to analyse associations with transcutaneous partial oxygen pressure (tcPO<sub>2</sub>), a conventional perfusion test result.</div></div><div><h3>Results</h3><div>The mean pedal transit time of the affected limbs in the non-healing group was longer than that in the healing group (19.1 ± 18.6 <em>vs</em>. 2.9 ± 2.1 seconds, <em>p</em> = .001). The mean peak pedal count of nucleotides in the non-healing group was lower than that in the healing group (24.4 ± 19.0 <em>vs</em>. 72.0 ± 36.1 counts/sec/GBq, <em>p</em> = .008). The pedal transit time and peak pedal count showed little to no correlation with the conventional tcPO<sub>2</sub> at the midfoot (<em>r</em> = 0.26 for pedal transit time; <em>r</em> = −0.11 for peak pedal count).</div></div><div><h3>Conclusion</h3><div>Two novel microcirculation parameters derived from RN angiography were associated with one year limb outcomes in patients with CLTI. Non-invasive radiotracer imaging derived parameters may provide an additional dimension to indices of pathophysiological microcirculation in CLTI.</div></div>","PeriodicalId":36502,"journal":{"name":"EJVES Vascular Forum","volume":"63 ","pages":"Pages 11-19"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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