H. Al-kuraishy, Ali I. Al-Gareeb, M. Monteiro, Heiam N. Hussein
{"title":"Covid-19 and Iraq: The exponential epidemic","authors":"H. Al-kuraishy, Ali I. Al-Gareeb, M. Monteiro, Heiam N. Hussein","doi":"10.53517/jckhh.2581-3331.422020209","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.422020209","url":null,"abstract":"The coronavirus disease 2019 (Covid-19) epidemic, which originated in Wuhan, China, has now extended to more than 200 countries and administrative regions infecting nearly 36,792,906 individuals of all ages as of 9 October 2020. Many of these articles pursue to investigate the epidemiological parameters of the disease at different locations to disseminate critical information among both modellers and policymakers for a timely control response to be implemented. Iraq has had 394,566 confirmed cases with 9,683 deaths according to the last update registration of Iraq Ministry of Health. In the infected region, despite unusual efforts to limit the movement of people at the expense of the Iraqi economy, we are dealing with an even greater fear that the number of patients who present to the emergency room will become much greater than the system can cope with. Finally, our analysis tends to suggest that measures to reduce transmission should certainly be implemented, as our government did on March 9, by inhibiting people’s movement and social activities, unless strictly required. The most effective way to contain this viral outbreak in Iraq is probably to avoid close contact at the individual level and social meetings.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130507208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of a case of Fournier’s gangrene after a perianal abscess debridement","authors":"M. Bhandari, N. Rao, P. Rao, B. Gopikrishna","doi":"10.53517/jckhh.2581-3331.422020210","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.422020210","url":null,"abstract":"Fournier’s gangrene is rapidly progressive and potentially fatal infective necrotising fasciitis affecting the external genitalia, perineal or perianal regions. Among many sources of infection, perianal surgical manipulation is one of the major contributing factors. A 45-years diabetic patient who had recently undergone surgical debridement elsewhere to treat a perianal abscess visited SDM Ayurvedic hospital with mild scrotal pain and an unhealthy surgical wound. He was treated surgically with broad-spectrum antibiotics, strict control of hyperglycemia, regular minimum debridement of wound and dressing with a Yashtimadhu taila (an herbal oil with Glycyrrhiza glabra, Emblica officinalis, Sesamum indicum and cow milk as active ingredients) famous for its wound healing property. The patient gradually recovered and the wound was gradually healed with secondary intention.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131130983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Semwal, K. Joshi, A. Pandian, P. Badoni, D. Semwal
{"title":"Biological applications and secondary metabolites of Saussurea costus (Falc.) Lipsch.","authors":"R. Semwal, K. Joshi, A. Pandian, P. Badoni, D. Semwal","doi":"10.53517/jckhh.2581-3331.412020201","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.412020201","url":null,"abstract":"Saussurea costus (Falc.) Lipsch. (Compositae), popularly known as Kuth in Ayurveda, is useful for gastrointestinal disorders in the form of a digestive agent, anti-gastric agent or an appetizer. Its roots have been used in respiratory problems like cough and asthma. The plant is also used in various other traditional medicinal systems including Unani. A number of scientific reports have proved its therapeutic importance as anti-gastric, anti-asthmatic, antispasmodic, antimicrobial and anti-inflammatory agent. A variety of secondary metabolites including sesquiterpenoid lactones, lignins, and phytosterols have been identified as bioactive principles from the roots of this plant. Today, many healthcare products are available in the market those contain S. costus roots as single or in the form of a polyherbal formulation. According to the IUCN Red List, S. lappa is under the threatened category and due to its high demand in the market, it is becoming extinct very fast from its natural habitat. Hence, there is an urgent need to protect the plant by promoting its cultivation on a large scale.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122576022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and challenges of herbal injectables – a possible emerging area of drug delivery","authors":"R. Semwal","doi":"10.53517/jckhh.2581-3331.412020204","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.412020204","url":null,"abstract":"Herbal drugs have been employed in the treatment of diseases since ancient time. People have confidence in their efficacy and safety even today. The main reason for the popularity of these drugs is their limited side-effects when consumed in the prescribed quantity. Despite their comparatively safe nature, their bioavailability and long gestation period remain challenging. This can be remedied by administering these drugs through parenteral routes in the form of herbal injectables. This article aims to draw the attention of the researcher toward the formulation and development of herbal injectables. Besides, the emphasis has given to the current scenario, challenges and perspectives of herbal injectables.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123777910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Senthamizh, R. Vidhyavathi, E. Raj, Vijaya Lobo, R. Kumar
{"title":"Reserpine subdued non-small cell lung cancer cells via ROS-mediated apoptosis","authors":"N. Senthamizh, R. Vidhyavathi, E. Raj, Vijaya Lobo, R. Kumar","doi":"10.53517/jckhh.2581-3331.422020206","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.422020206","url":null,"abstract":"Non-small cell lung cancer (NSCLC) is the prevailing kind of lung cancer. Molecular target has exceptionally improved the treatment viability of lung cancer, however, new difficulties have developed, for example, drug resistance and cancer repeat. Along these lines, new chemotherapeutic operators and treatment techniques are earnestly required. Reserpine, a natural indole alkaloid, is the fundamental dynamic piece of Indian restorative plant which has been appeared to show ground-breaking hostile to cancer action in specific kinds of cancer; be that as it may, its movement in drug-safe lung cancer has never been tended to. In this investigation, we utilized 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT) measure and 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) test to examine reserpine anticancer movement. The cytotoxicity of reserpine in NSCLC cell lines was profoundly investigated. Reserpine displayed specific cytotoxicity among NSCLC at 15, 25 and 35 μM concentrations. Reserpine essentially expanded the action of ROS, which are profoundly expanded apoptosis. Improved ROS, altogether initiated customized cell passing in human NSCLC cells. The upgrade of ROS age in drug-safe NSCLC cells prompts impedance of development and acceptance of apoptosis. In this way, reserpine-prompted cell apoptosis is firmly connected with ROS rise in the cells. These discoveries show that reserpine can be a powerful mix of treating drug-safe NSCLC.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124651244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Marma therapy – a drug-less treatment for neurological disorders","authors":"Sunil Kumar Joshi","doi":"10.53517/jckhh.2581-3331.322019200","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.322019200","url":null,"abstract":"According to medical science, the specific parts of the body, which are very vulnerable to trauma, are known as Marma. Any trauma to these places may lead to death or many other complications regarding physiological functions and anatomical configuration. So, during any surgical intervention/ para-surgical procedures, one has to take care of these vital points. As we know, in accidental cases, some people die without massive outside injuries but some survive despite of having extensive injuries and become healthy later on after proper treatment. That is because the vital points (Marma) are injured and a person dies immediately. Therefore, these vital points are important for the survival of human beings. On the other hand, the stimulation of these points is important to treat a number of diseases both in acute and chronic conditions because these places are known as vital parts and are the source of energy. In the present situation where the whole of medical science is away from the reach of the common man due to its expensiveness and hazards, it is highly essential to take the privilege of making Marma science and therapy as a mainstream treatment mainly for pain management as in case of Ayurveda, instant pain management is a big issue.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134544799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A clinical study to evaluate the liver regeneration effect of L-arginine","authors":"Manal F. Al-Khaqani","doi":"10.53517/jckhh.2581-3331.322019198","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.322019198","url":null,"abstract":"The liver is important for protein synthesis, detoxification, and amino acid metabolism. Nitric oxide (NO) is a key mediator in hepatocyte proliferation during liver regeneration. It is an oxidative metabolite of L-arginine produced by enzymes called nitric oxide synthase. The aim of this study is to evaluate the effect of Larginine on the liver functions of patients with liver disorders and to explore the role of L-arginine in the pathogenesis of the liver. The biochemical tests of the liver like ALT, AST, and ALP were done in the groups. The treatment with L-arginine as a test drug showed a significant decrease in the levels of biochemical markers to the nearnormal levels. The study concluded that the treatment with formulations containing Larginine helped in regaining the normal hepatic architecture.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129527587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cultivation and sustainable use of high-altitude medicinal and aromatic plants for the socio-economic development","authors":"D. K. Semwal","doi":"10.53517/jckhh.2581-3331.322019199","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.322019199","url":null,"abstract":"The Uttarakhand Ayurved University (UAU) was established by the Government of Uttarakhand vide Uttarakhand Ayurved University Act, 2009 as a dream project of Devbhumi Uttarakhand to promote education and research on Ayurved and herbal medicine. The University is spread in 25 acres of land at Harrawala, Dehradun. Besides already established faculties (Faculty of Ayurved and Faculty of Biomedical Sciences), the University is in progress to establish faculty of Yoga and Naturopathy, Pharmaceutical sciences, Homeopathy, Unani and Siddha System of medicine. University has three Campuses; the main campus is situated at Harrawala, Dehradun and centaury old historical campuses Rishikual and Gurukul are at Haridwar Uttarakhand. The university is recognized by UGC, New Delhi and CCIM, New Delhi, and currently running almost all courses of AYUSH Education at UG, PG and PhD level including BAMS, BUMB, BHMS, MD/MS, PhD, etc.. Nineteen 19 Ayurvedic, Homoeopathic and Unani Colleges are affiliated to the University. The University has centre of excellence in Panchakarma and Marma Chikitisa.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121443237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A conceptual study of Agni with respect to disease formation (Rogotpatti)","authors":"U. Dwivedi","doi":"10.53517/jckhh.2581-3331.322019197","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.322019197","url":null,"abstract":"According to Ayurveda, Ahar sambhavam vastu rogashch ahar sambhavah, which means, body is the outcome of food and so is the disease. Under normal conditions, food provides energy for body‟s functions and building material for growth and repair. Most of the food substances require changes before utilization. These changes begin with the culinary and end in the intestine with digestion. Cooking and digestion both require heat energy given in any form. Heat energy required for digestion is known as pachakagni in Ayurveda. The entire process (digestionmetabolism) of conversion of food is performed successively by Pachakagni, Bhootagni and Dhatwagni. The present article focuses on how does the normalcy of these Agnis causes ahar sambhavam vastu and abnormality causes rogastu ahar sambhavah on the basis of Ayurvedic and modern science.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120920555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A randomized clinical trial on Guduchiyadi gana kwatha in the management of amlapitha (acid peptic disease)","authors":"Syyed Mohammed Jalaludheen","doi":"10.53517/jckhh.2581-3331.322019196","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.322019196","url":null,"abstract":"Amlapitha (acid peptic disease) has a population prevalence of 6% and a malefemale ratio of 1.7:1 in a study population of 10,096 urban dwellers. Two third of which constituted cases of duodenal ulcer and there has been a rapid rise in the 20th century globally. Amlapitha is a very common medical condition and the current management available for the same is not comprehensive. The aim of the present study is to assess the efficacy of guduchiyadi gana kwatha in the management of amlapitha. Ayurveda has a rich tradition in the management of gastroenterological disorders, but, due to reasons unknown, the full potential of Ayurvedic wisdom has not been explored so far in its management. Even the existing management is so trifled considering the plethora of management, principles and practice. So, it is highly essential that simple and cheap but effective formulation should be brought to the fore and the benefits of this great science to be extended to the suffering humanity. This would further help to popularize the system of Ayurveda. Existing treatment modalities available in Ayurveda for amlapitha are expensive, timeconsuming and results unsatisfying. So, any initiative that would curtail the high cost and enhance the efficacy would be most welcomed. The existing kalpas used for amlapitha are composed of multiple drugs out of which some drugs are not available today. So, the simple formulation of guduchiyadi gana kwatha mentioned in Ashtanga Hrudaya would be highly practical considering the low cost and high availability of the drugs. Moreover, guduchiyadi gana is the best for the management of amlapitha.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130334996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}