Sunil Kumar Joshi, R. Semwal, Amit Kumar, A. Chauhan, D. Semwal
{"title":"Indian cow and A2 beta-casein – A scientific perspective on health benefits","authors":"Sunil Kumar Joshi, R. Semwal, Amit Kumar, A. Chauhan, D. Semwal","doi":"10.53517/jckhh.2581-3331.512021212","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.512021212","url":null,"abstract":"The cow has a special place in Hinduism since time immemorial due to the diverse health benefits of its products called Panchagavya. Ayurveda has well-described the medicinal benefits of cow milk, curd, ghee, dung and urine in indigestion, microbial infections, hormonal imbalance and neurological disorders. Indian cows are well-known for producing A2 beta-casein proteincontaining milk which is useful in hormonal disorders including diabetes, hypertension and dyslipidemia. On the other hand, milk containing A1 genotype of beta-casein has been considered to be harmful to health. Cow milk is proven to be a most nutritious food with the bio-protective effect which contains carotenes, vitamin A, vitamin B complex and vitamin C together with flavones, sterols and phenols. The present manuscript describes a general comparison between A1 and A2 variants of beta-casein based on scientific evidence. In view of the health benefits, the present work mainly emphasizes the conservation and propagation of indigenous Indian cow.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132841210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A retrospective survey on the relationship between Prakriti (body constitution) and mental health","authors":"A. B. Dharmarathna, W. Kulathunga","doi":"10.53517/jckhh.2581-3331.512021213","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.512021213","url":null,"abstract":"Prakriti of a person means original creation that is translated as a person’s constitution. There are two types of Prakriti viz. Shareerika and Manasika are described in ancient Ayurveda texts. While Vata, Pitta and Kapha determine the characteristics of the body (Shareere), the Sattva, Rajas and Tamo Guna are said to influence the attitudes and behaviour of an individual. Mental status can be defined as a comprehensive description or statement of a patient’s intellectual capacity, emotional state and general mental health based on the examiner's observations and directed interview including assessment of mood, behaviour, orientation, judgment, memory, problem-solving ability and contact with reality. The present study aims to establish the interrelationship between Prakriti and mental state and to find out the socio-demographic characteristics of the participants. A retrospective survey was conducted on Ayurvedic Medical Officers with the help of Bachelor of Ayurveda Medicine and Surgery graduates. All the participants were between the age group of 20-45 years. Both males and females were included in the training programme at the Institute of Indigenous Medicine, University of Colombo. A selfassessment questionnaire was used for the survey. In the present study, the majority of participants belong to the age group between 31-40 years (92.8%) of which 88% of participants were females. It has been found that the majority of the participants were living in the Suburban area (49.4%) and their education level was recorded till graduation. The present study revealed that 56.6% of participants have Sathwa Manasika Prakriti whereas 44.6 participants have PittaKapha Shareerika Prakriti. The mental state revealed 81.95% of normal, 13.3% of mild and 4.8% of moderate mental status. The study concludes that there was a significant relationship between Manasika Prakriti and mental status (p = 0.008) whereas the relationship of Shareerika Prakriti with mental status was found insignificant (p = 0.287).","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123490641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ayurvedic concept of immunity with special reference to immunomodulatory herbs","authors":"Neha Saini, Vikas Saini","doi":"10.53517/jckhh.2581-3331.512021214","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.512021214","url":null,"abstract":"A systematic literature review on immunomodulatory herbs of Ayurveda was conducted to explore their clinical potential. A variety of plant-based principles with potential immunomodulatory action have been identified, which may explain and justify their usage in traditional medicine in the past and can also serve as a foundation for future studies. This review aims to highlight the findings of research on plant-derived immunomodulators. Focusing the ethnopharmacological usage, the most relevant articles were chosen from the authentic databases of biomedical sciences. Different scientific online databases including Academic Search Premier, Embase, PubMed, Biological Abstracts, PLOS, Natural Standard, and Web of Science were used to conduct the present systematic literature search. Many plants, as well as certain phytoconstituents, have been implicated in the present study. The study also focuses on the mechanism of action of different plant medicines. The present review would be helpful in designing new research studies on medicinal plants with immunomodulatory properties.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125917816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Witchcraft and Myths about Covid-19 in Iraq","authors":"H. Al-kuraishy","doi":"10.53517/jckhh.2581-3331.512021211","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.512021211","url":null,"abstract":"Coronavirus disease (Covid-19) is an infectious disease caused by the SARS-CoV-2 virus that has recently appeared in China and had caused a million of infections and thousands of deaths. This epidemic has spread widely, such as wildfire and lethality in European countries and the United States of America. Those countries have faced this epidemic in scientific ways, and have taken measures of regional isolation and quarantine, as well as experimental and clinical research in pursuit of a successful drug or vaccine (Al-Kuraishy et al., 2020a; 2020b).","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128436755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. A. Owonaro, J. Arute, Benedicta C. Uweru, J. Eniojukan
{"title":"Health seeking behavior among tertiary school female students with Dysmenorrhea in Delta State, South-South, Nigeria","authors":"P. A. Owonaro, J. Arute, Benedicta C. Uweru, J. Eniojukan","doi":"10.53517/jckhh.2581-3331.512021215","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.512021215","url":null,"abstract":"Dysmenorrhea, also referred to as painful menstruation, is a common chronic pelvic pain syndrome that affects women that are of childbearing age and it is positively linked with recurrent short-term absence from school among adolescent girls accompanied by diminished health-related quality of life. This study examined various correlates of healthcare-seeking behavior for dysmenorrhea among female students in three tertiary institutions in the Delta state of Nigeria. The research design was cross-sectional employing the questionnaire as a research instrument. A total of 400 female students randomly selected in the three tertiary institutions, filled and returned the questionnaire. Descriptive and inferential methods were used to analyze the data. The most recurring age groups in COE and DELSU were 16-21years (49.3% and 54% respectively) while DSSH was 22-27years (39%). Over 75% of all respondents were single;. Across the institutions, the majority (26.3%) visited the chemist, 22.3% the pharmacy, 13.0% the hospital and 1.5% sought health care from herbal and spiritual homes. For self-medication, 59.8% used Paracetamol and 1.5% resorted to herbs to relieve menstrual pain. Generally, more people patronized private health facilities; there was a significant difference across educational institutions (p<0.05) in the first point of call during menstrual pains/cramps, Self-medication usage, Herbal preparation usage and Effectiveness of self-medication. The use of self-medication had a relationship with the severity of cramps in all institutions, [COE (p=0.009), DELSU (p=0.036) and DSSH (p=0.036). Overall, the magnitude of appropriate healthcare-seeking behavior was satisfactory","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117279092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronil – What is dispute if it is developed from time-tested Ayurvedic Science?","authors":"D. Semwal","doi":"10.53517/jckhh.2581-3331.412020202","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.412020202","url":null,"abstract":"The discussion about Coronil, a new COVID-19 herbal medicine of Patanjali Ayurved, Ltd. (Times of India, 2020) is on all over the world. Some groups are challenging its efficacy and some its process of development (Business Standard, 2020). However, we need to understand the actual facts about the product, Coronil (Fig. 1) and its effectiveness before participating in any of the arguments related to this drug.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133507751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preliminary phytochemical analysis and antibacterial study of crude extract from Hamelia patens stems","authors":"V. Kanchana, G. Kumar, R. Shalini","doi":"10.53517/jckhh.2581-3331.422020207","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.422020207","url":null,"abstract":"The present study aimed to analyse the phytochemical and antibacterial activity of different extracts of the tropical plant Hamelia patens Jacq. (Rubiaceae). The antimicrobial activity was carried out using agar well diffusion method. Hexane, petroleum ether, ethanol and chloroform stem extracts (100 μL of 50 mg/mL each) were introduced into the wells separately and allowed it to undergo incubation. After the incubation time was over, the plates were observed for zones of inhibition and compared with positive control ciprofloxacin at a concentration of 30 μM. These results provided evidence that the tested plant extracts possess antimicrobial properties which can be tested further in the development of novel antimicrobial agents.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133561819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative clinical study of khakhasa beeja lepa and nimba patra churna lepa in the management of darunaka (dandruff)","authors":"Bhavana Vinayak Bhat, J. Nagaraja","doi":"10.53517/jckhh.2581-3331.422020208","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.422020208","url":null,"abstract":"Dandruff, a scalp disorder, affects the population of worldwide which is although not a transmitted disease but caused a social or self-esteem problem. Itching and flakiness are the common causes of dandruff which can also affect the facial skin if not treated in time. As per Ayurveda texts, dandruff can be correlated with Darunaka and vata and kapha doshas might be responsible for its development. This study used a paste of khakasa beeja (Papaver somniferum) and godugdha (cow milk) to treat dandruff which is also mentioned in Ayurvedic Samhitas for the treatment of darunaka condition. A total of 60 patients have been enrolled for this study in which 30 patients were given above treatment while the rest of the 30 patients were treated with neem paste. The study suggested that the khakasa beej and godugdha paste has the potential to treat dandruff.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"53 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113971695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic and culinary uses of Benincasa hispida (Alupuhul)","authors":"S. Waidyarathna, E. Ediriweera","doi":"10.53517/jckhh.2581-3331.412020203","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.412020203","url":null,"abstract":"Benincasa hispida (Thunb.) Cogn. (Cucurbitaceae) is commonly called as winter melon or ash melon. It is a popular vegetable crop, especially among Asian communities both for nutritional and medicinal purposes. It has been used as a medicinal plant by Ayurvedic and Sri Lankan traditional physicians since antiquity. It is used singly or in various formulations in combination with different medicaments in Ayurveda and traditional medicine. The literature for the present review was gathered from Ayurvedic texts, traditional medical texts, books on plant science, modern medicinal texts, journals and online scientific tools. The fruits, pericarp, seeds, stems, roots and leaves of this plant are used in various preparations. It is used in internal treatment for urinary disorders including calculi, dysuria, pain in pelvis and genitals, disorders like gastritis, gastric ulcers, worm infestation, hiccough, hyperdipsea, anaemia, jaundice, diabetes mellitus, piles, fever, internal haemorrhages, hemoptysis, general debility, epilepsy, cough, hoarseness, all kinds of asthma, bronchitis, tuberculosis, ulceration of lungs, heart diseases, testosterone-induced prostatic hypertrophy and especially in the vitiated condition of Pitta Dosha. Externally, it showed anti-inflammatory, anti-asthmatic and antimicrobial effects. Rejuvenate, antioxidant, anti-ageing, nutritive, tonic, diuretic, aphrodisiac, nephron protective, styptic, vermin fugue, antidiabetic, hyperlipidemic, anxiolytic, muscle relaxant, antidepressant and antimicrobial in properties of Benincasa hispida are scientifically proven. It is concluded that Benincasa hispida is with multi-faceted medicinal values.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116825872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Chandravadhana, Vijaya Lobo, R. Vidhyavathi, E. Raj, Arun Kumar Ramu
{"title":"Tea flavonoid theaflavin induces apoptosis in hepatocellular carcinoma cells through improving ROS level","authors":"V. Chandravadhana, Vijaya Lobo, R. Vidhyavathi, E. Raj, Arun Kumar Ramu","doi":"10.53517/jckhh.2581-3331.412020205","DOIUrl":"https://doi.org/10.53517/jckhh.2581-3331.412020205","url":null,"abstract":"Flavonoids, a class of normal polyphenolic mixes, restrain cell cycle movement and instigate apoptosis. This examination was performed to explore the anticancer effect of theaflavin, a natural flavonoid found in the leaves of tea plant Camellia sinensis. Although this molecule was found to inhibit several cancer cells, the specific anticancer action in liver cancer remains unexplored, especially in human hepatocellular carcinoma (HepG2) cells. Henceforth, the present study was designed to elucidate the anticancer activity in HepG2 cells, level of reactive oxygen species (ROS) in the cancer cells and tumour cell apoptosis. The action of theaflavin in provocation apoptosis was explored through the improved ROS by MTT assay and 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) method. As per the results obtained from the MTT assay, theaflavin had cell hindrance effect on HepG2 cells. The IC50 estimation of theaflavin to hindered cell development at 25, 50 and 75 μM concentration and instigating apoptosis through ROS improvement. The progressions in mitochondrial morphology, portion conditionally that diminished cell expansion, were seen in various concentrations of the drug treatment. In this manner, theaflavin might be useful as a chemotherapeutic agent for the treatment of liver cancer.","PeriodicalId":365000,"journal":{"name":"JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134324681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}