JBI evidence synthesis最新文献

{"title":"Paradigmatic perspectives of research on the self-regulated learning of non-western learners in health professions education: a scoping review protocol.","authors":"Farah Yoosoof, Fathima Rizka Ihsan, Steven Agius, Neil Coulson, Kate Freeman, Nicola Cooper","doi":"10.11124/JBIES-24-00144","DOIUrl":"https://doi.org/10.11124/JBIES-24-00144","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review will be to explore the paradigmatic perspectives of research on self-regulated learning in non-western learners in health professions education.</p><p><strong>Introduction: </strong>Studies show that there are significant cultural differences in self-regulated learning. However, a predominantly positivistic research paradigm, attempting to fit cross-cultural populations into pre-defined western conceptualizations of self-regulated learning, has led to the disregard of these differences. Viewed from a critical realist paradigm, emerging evidence suggests the need for generalizable, yet culturally sensitive models. Given the relevance of self-regulated learning to success in an increasingly diverse health professions setting, the first step towards achieving this is to gain a systematic understanding of the paradigms of research on self-regulated learning in non-western learners in this context.</p><p><strong>Inclusion criteria: </strong>Primary research on the self-regulated learning of non-western learners in health professions education will be included. Participants will include learners in the Global South, including learners from Japan and South Korea, based on study setting. Studies on self-regulation and self-directed learning will not be included.</p><p><strong>Methods: </strong>This review will be conducted in accordance with the JBI methodology for scoping reviews. The following databases will be searched: MEDLINE (Ovid), CINAHL (EBSCOhost), ASSIA, PsycINFO (Ovid), ERIC (EBSCOhost), Web of Science Core Collection, CKNI, Epistemonikos, and LILACS. Gray literature will be searched for in Google Scholar, ProQuest Dissertations and Theses, and DART-Europe. There will be no date or language restrictions. Following independent title and abstract screening by 2 reviewers, data will be extracted into a piloted data extraction tool, which will be iteratively revised as needed. Analyzed data will be presented in graphs and tables, accompanied by a narrative summary.</p><p><strong>Details of the review project available at open science framework: </strong>https://osf.io/gf2ez.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune biomarkers and secondary hemophagocytic lymphohistiocytosis: a scoping review protocol.","authors":"Alice Terrett, Magalie Van Loo, Krishnaswamy Sundararajan, David Brealey, Mervyn Singer, Jessica Manson, Eamon Patrick Raith","doi":"10.11124/JBIES-24-00133","DOIUrl":"https://doi.org/10.11124/JBIES-24-00133","url":null,"abstract":"<p><strong>Objective: </strong>To identify immunological pathways and markers of severity of illness associated with clinical outcomes that may represent potential therapeutic targets in the management of secondary hemophagocytic lymphohistiocytosis.</p><p><strong>Introduction: </strong>A broad range of immunomodulatory therapies is used to manage hemophagocytic lymphohistiocytosis, however the supporting evidence for these therapies is scarce. Identifying patients likely to experience more severe disease, or die, is currently extremely difficult, if not impossible. The identification of implicated cytokines in secondary disease can provide further support for the identification of high-risk patients and the development of targeted therapies.</p><p><strong>Inclusion criteria: </strong>Studies reporting immune biomarker and cytokine measurement in adult patients (age >18 years) with secondary hemophagocytic lymphohistiocytosis.</p><p><strong>Methods: </strong>The proposed review will be conducted in line with the JBI methodology for scoping reviews. The MEDLINE (Ovid) and Embase (Ovid) databases will be searched, without date limitations. Data will be extracted using a data extraction tool developed by the reviewers. Relevant sources will be retrieved, and their citation details imported into the JBI System for the Unified Management, Assessment and Review of Information.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of natural environment use by occupational therapists working in mental health care: a scoping review.","authors":"Ruth Bishop, Frazer Underwood, Fiona Fraser, Lisa Burrows, Jill Shawe","doi":"10.11124/JBIES-23-00437","DOIUrl":"https://doi.org/10.11124/JBIES-23-00437","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this review was to identify and characterize the use of the natural environment/outdoor space by occupational therapists working in mental health care. This included consideration of the characteristics of the environment used, interventions, mental health conditions being treated, and the outcomes being used.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Research has demonstrated the link between human health and the environment. The benefits appear to be particularly relevant to people with mental health conditions. Occupational therapists already consider the environment when assessing and developing interventions, and therefore are well placed to consider and use the natural environment in mental health practice. However, the use of the natural environment by occupational therapists working in mental health is unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Inclusion criteria: &lt;/strong&gt;The scoping review included any publication relating to the use of the natural environment/outdoor space in mental health occupational therapy practice. All forms of the natural environment or outdoor space were included, such as hospital gardens and local parks. There were no geographical, gender, or age restrictions. All mental health diagnoses were eligible for inclusion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Seven databases were searched: Embase (Ovid), Emcare (Ovid), MEDLINE (Ovid), PsycINFO (ProQuest), AMED (Ovid), Trip Database, and CINAHL (EBSCOhost). Gray literature was also searched using a selection of websites and digital repositories. Papers written in English were searched, with no time limit set on publication. Titles and abstracts were screened by 2 independent reviewers for assessment against the inclusion criteria, followed by a full-text review and data extraction. Data were extracted using the data extraction tool developed by the authors. Findings were presented in a tabular format, accompanied by a narrative summary describing how the results relate to the review objectives and question.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of peer-reviewed publications, 7 papers used qualitative methods and 7 used mixed methodology. The remaining sources included conference abstracts, unpublished works, a book chapter, and a website article. The environments used included forests, beaches, gardens, and parks. A variety of interventions were delivered in these environments, including gardening and nature-based activities, physical activities, and animal-assisted interventions. Such activity-focused interventions are largely delivered in a group context, thus providing a social element. A diverse range of mental health conditions were treated. Several methods were used to consider the outcomes on the individual, including both qualitative measures and quantitative outcome measurement tools.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The review highlights many characteristics of how the natural environment is being used across mental health services by occupatio","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Return on investment of tobacco control measures: a systematic review protocol.","authors":"Paramita Bhattacharya, Sajda Khatoon, Suraya Roy, Nirmalya Mukherjee, Amit Yadav, Pranay Lal, Subhash Pokhrel, Denny John","doi":"10.11124/JBIES-23-00371","DOIUrl":"https://doi.org/10.11124/JBIES-23-00371","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this systematic review will be to estimate the return on investment (ROI) and social return on investment (SROI) on tobacco control measures.</p><p><strong>Introduction: </strong>Tobacco consumption has been proven to be associated with a huge epidemiological, humanistic, and economic burden. National and international organizations are making concerted efforts to control tobacco use. However, currently, there are no conclusive estimates of the ROI and SROI of such programs and policies.</p><p><strong>Inclusion criteria: </strong>This review will include all studies that evaluate the ROI or SROI on tobacco control programs and policies on tobacco users and probable tobacco users globally.</p><p><strong>Methods: </strong>This review will follow the JBI methodology for systematic reviews of economic evidence. Databases to be searched will include Embase (Ovid), MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), Health Economic Evaluation Database (HEED), National Health Service Economic Evaluation Database (NHS EED), CEA Registry, LILACS, Science Direct, Web of Science, EconLit, and Google Advanced Search. Gray literature will also be searched for in non-academic databases, including the websites of various civil societies and non-governmental organizations involved in tobacco control. Two independent reviewers will screen titles/abstracts, and later full-text studies. Critical appraisal will be conducted using the JBI checklist for economic evaluations and the SROI Quality Framework. Data will be extracted and synthesized using JBI data extraction forms and synthesis tools. The MPOWER framework will be considered for data synthesis across all selected studies using narrative synthesis, tables, and figures.</p><p><strong>Systematic review registration number: </strong>PROSPERO CRD42023391591.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated care for adults with chronic musculoskeletal disorders: a scoping review protocol.","authors":"Mulugeta Bayisa Chala, Jacobi Elliott, G Ross Baker, David M Walton, Micheline Steele, Siobhan Schabrun","doi":"10.11124/JBIES-23-00534","DOIUrl":"https://doi.org/10.11124/JBIES-23-00534","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this scoping review is to describe the current evidence exploring integrated care for people with chronic musculoskeletal disorders.</p><p><strong>Introduction: </strong>The integrated model of care is an emerging approach to delivering person-centered care. Integrated care supports the management of people with major chronic health conditions; however, the evidence behind its use to support people with chronic musculoskeletal disorders is scant. This scoping review will synthesize how integrated care is conceptualized, delivered, and evaluated for people with chronic musculoskeletal disorders. The review will also synthesize the attributes, components, elements, goals, frequently evaluated outcomes, theories/frameworks, and facilitators and barriers to delivering this model among people with musculoskeletal disorders.</p><p><strong>Inclusion criteria: </strong>Studies conducted on the delivery and/or evaluation of integrated care for people with chronic musculoskeletal disorders in any health care setting (eg, primary, secondary, tertiary) and/or geographical location (countries, cultures) will be considered.</p><p><strong>Methods: </strong>The review will follow the JBI scoping review methodology. Databases such as MEDLINE (Ovid), CINAHL (EBSCOhost), Scopus, Embase (Ovid), PsycINFO (Ovid), the JBI EBP Database, PEDRO, Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and Web of Science, as well as sources of gray literature will be thoroughly searched. Papers published in all languages will be considered. Two reviewers will independently review the selected articles and extract data using a data extraction tool developed for this scoping review. The analysis will involve numerical and descriptive summaries of the selected articles and will be presented using graphs and tables, in line with Preferred Reported Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR).</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informal caregivers' feeding experiences for children with cancer: a qualitative systematic review protocol.","authors":"Donruedee Kamkhoad, Tippawan Srichalerm, Porawan Witwaranukool","doi":"10.11124/JBIES-24-00081","DOIUrl":"https://doi.org/10.11124/JBIES-24-00081","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review is to synthesize the experiences of informal caregivers' feeding practices for children with cancer.</p><p><strong>Introduction: </strong>Changes in eating among children with cancer impact their nutritional status, leading to several negative outcomes. In addition to interventions given by health care providers, informal caregivers' experiences in feeding these children are worth exploring.</p><p><strong>Inclusion criteria: </strong>This review will include qualitative studies or the qualitative component of mixed method studies examining informal caregivers' experiences of feeding children with cancer under 18 years old, published in English or Thai in any year up to the present.</p><p><strong>Methods: </strong>This review will follow the JBI approach for qualitative systematic reviews. A full search strategy for MEDLINE (PubMed) was developed from an initial limited search of MEDLINE (PubMed) and CINAHL (EBSCOhost) to identify articles on the topic. The search strategy will be adapted for each database, including Embase (Ovid), MEDLINE (PubMed), CINAHL (EBSCOhost), Cochrane Library (CENTRAL), LILACS (BVS), PsycINFO (Ovid), Web of Science, Scopus, and ThaiJO (TCI). The reference lists of studies included in the review will be hand-searched for additional studies. Sources of unpublished studies and gray literature will also be searched. Two reviewers will separately screen for eligible studies, perform the critical appraisal, and extract data. They will then synthesize via meta-aggregation and summarize the data. The final synthesized findings will be graded using the ConQual approach to establish confidence in the qualitative research synthesis.</p><p><strong>Review registration: </strong>PROSPERO CRD42024501382.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological burden of inborn errors of metabolism in low- and middle-income countries: a systematic review protocol.","authors":"Kavita Kachroo, Annie NithiyaVathani Johnson, S A K Moinudeen, Jitendra Sharma, Cheryl Holly","doi":"10.11124/JBIES-23-00540","DOIUrl":"https://doi.org/10.11124/JBIES-23-00540","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review examines the evidence on the incidence and prevalence of inborn errors of metabolism (IEMs) in low- and middle-income countries (LMICs).</p><p><strong>Introduction: </strong>IEMs are a set of conditions that can either be inherited or result from spontaneous mutations. Although each condition is rare in isolation, various specific disorders within the IEM group have an estimated global prevalence of 50.9 per 100,000 live births. A precise estimate of the prevalence and incidence of IEM in LMICs can help determine the necessity for extensive newborn screening programs.</p><p><strong>Inclusion criteria: </strong>This review will cover studies conducted in LMICs, reporting on IEMs in infants and children under the age of 5 years. Studies that calculate birth prevalence and incidence of IEM will be included. Studies that provide information on the causes, clinical characteristics, treatment, case fatality rates, mortality rates, and other outcomes will also be considered.</p><p><strong>Methods: </strong>The databases to be searched include PubMed, MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Scopus, and gray literature sources. No date or language restrictions will be applied. Our search will encompass analytical and descriptive observational studies, which will be critically appraised by 2 independent reviewers. Data will be extracted using JBI data extraction tools. If sufficient data are available, a meta-analysis will be performed. Alternatively, if data are limited, we will present our findings in narrative format using tables and figures.</p><p><strong>Review registration: </strong>PROSPERO CRD42023457421.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing strategies to address health disparities in genomics-informed care: a scoping review.","authors":"Jacqueline Limoges, Patrick Chiu, Dzifa Dordunoo, Rebecca Puddester, April Pike, Tessa Wonsiak, Bernadette Zakher, Lindsay Carlsson, Jessica K Mussell","doi":"10.11124/JBIES-24-00009","DOIUrl":"10.11124/JBIES-24-00009","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this review was to map the available global evidence on strategies that nurses can use to facilitate genomics-informed health care to address health disparities to inform the development of a research and action agenda.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The integration of genomics into health care is improving patient outcomes through better prevention, diagnostics, and treatment; however, scholars have noted concerns with widening health disparities. Nurses work across the health system and can address health disparities from a clinical, research, education, policy, and leadership perspective. To do this, a comprehensive understanding of existing genomics-informed strategies is required.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Inclusion criteria: &lt;/strong&gt;Published (qualitative, quantitative, mixed methods studies, systematic and literature reviews and text and opinion papers) and unpublished (gray) literature that focuses on genomics-informed nursing strategies to address health disparities over the last 10 years were included. No limitations were placed on language.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The review was conducted in accordance with the JBI methodology for scoping reviews. A search was undertaken on May 25, 2023, across 5 databases: MEDLINE (Ovid), Embase, Cochrane Library (Ovid), APA PsycINFO (EBSCOhost), and CINAHL (EBSCOhost). Gray literature was searched through websites, including the International Society of Nurses in Genetics and the Global Genomics Nursing Alliance. Abstracts, titles, and full texts were screened by 2 or more independent reviewers. Data were extracted using a data extraction tool. The coded data were analyzed by 2 or more independent reviewers using conventional content analysis and the summarized results are presented using descriptive statistics and evidence tables.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In total, we screened 818 records and 31 were included in the review. The majority of papers were published in either 2019 (n=5, 16%), 2020 (n=5, 16%), or 2021 (n=5, 16%). Most papers came from the United States (n=25, 81%) followed by the Netherlands (n=3, 10%), United Kingdom (n=1, 3%), Tanzania (n=1, 3%) and written from a global perspective (n=1, 3%). Nearly half the papers discussed cancer-related conditions (n=14, 45%) and most of the others did not specify a disease or condition (n=12, 30%). In terms of population, nurse clinicians were mentioned the most frequently (n=16, 52%) followed by nurse researchers, scholars, or scientists (n=8, 26%). The patient population varied, with African American patients or communities (n=7, 23%) and racial or ethnic minorities (n=6, 19%) discussed most frequently. The majority of equity issues focused on inequitable access to genetic and genomics health services amongst ethnic and racial groups (n=14, 45%), individuals with lower educational attainment or health literacy (n=6, 19%), individuals with lower socioeconomic status (n=3, 10%), migrants (n=","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies to increase accessibility for students with disabilities in health professional programs: a scoping review protocol.","authors":"Shaminder Dhillon, Michelle Ira Roque, Dina Brooks, Sarah Wojkowski","doi":"10.11124/JBIES-23-00484","DOIUrl":"https://doi.org/10.11124/JBIES-23-00484","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this scoping review will be to identify strategies in the literature that may increase the accessibility of health professional programs for students with disabilities.</p><p><strong>Introduction: </strong>The number of students with disabilities in health professional programs is increasing. However, since students with disabilities experience barriers to education, their retention rates are potentially lower, and their attrition rates are potentially higher compared with their non-disabled peers.</p><p><strong>Inclusion criteria: </strong>Academic and gray literature that identifies strategies intended to increase accessibility to health professional programs for students with disabilities will be included. Only articles published from 2000 onward will be considered for inclusion.</p><p><strong>Methods: </strong>This review will follow the JBI methodology for scoping reviews. Databases to be searched will include Embase (Ovid), MEDLINE (Ovid), PsycINFO (Ovid), CINAHL (EBSCOhost), ERIC (ProQuest), and Web of Science. Gray literature will be searched for using Google. Websites of known disability organizations will also be searched. There will be no language limitations. Paired reviewers will independently screen titles and abstracts, and then full-text articles. Data will be extracted using a tool developed by the reviewers. The extracted data will be synthesized and reported in tabular format, accompanied by a narrative summary connecting the results to the objective of the review.</p><p><strong>This scoping review protocol was registered in open science framework: </strong>https://doi.org/10.17605/OSF.IO/BSYRT.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining the exit meta-analysis.","authors":"Jazeel Abdulmajeed, Luis Furuya-Kanamori, Tawanda Chivese, Chang Xu, Lukman Thalib, Suhail A R Doi","doi":"10.11124/JBIES-24-00155","DOIUrl":"https://doi.org/10.11124/JBIES-24-00155","url":null,"abstract":"<p><strong>Introduction: </strong>In recent decades, clinical research has seen significant advancements, both in the generation and synthesis of evidence through meta-analyses. Despite these methodological advancements, there is a growing concern about the accumulation of repetitive and redundant literature, potentially contributing to research waste. This highlights the necessity for a mechanism to determine when a meta-analysis has conclusively addressed a research question, signaling no further need for additional studies-a concept we term an \"exit\" meta-analysis.</p><p><strong>Methods: </strong>We introduced a convergence index, the Doi-Abdulmajeed Trial Stability (DAts) index, and a convergence plot to determine the exit status of a meta-analysis. The performance of DAts was examined through simulation and applied to two real-world meta-analyses.</p><p><strong>Results: </strong>The DAts index and convergence plot demonstrate highly effective discriminative ability across varying study scenarios. This represents the first attempt to define an exit meta-analysis using a quantitative measurement of stability (as opposed to sufficiency) and its corresponding plot. The application to real-world scenarios further validated the utility of DAts and the convergence plot in identifying a conclusive (exit) meta-analyses.</p><p><strong>Conclusion: </strong>The new development of DAts and the convergence plot provide a promising tool for investigating the conclusiveness of meta-analyses. By identifying an exit status for meta-analysis, the scientific community may be equipped to make better-informed decisions on the continuation of research on a specific topic, thereby preventing research waste and focusing efforts on areas with unresolved questions.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}