JBI evidence synthesis最新文献

{"title":"Effectiveness and safety of intranasal fentanyl for pain management in infants aged 0-6 months: a systematic review protocol.","authors":"Helen McCord, Melissa Rothfus, Tim Disher, Nadeana Norris, Karlee Jones, Laila Kristoffersen, Maria Syverud, Marsha Campbell-Yeo","doi":"10.11124/JBIES-24-00376","DOIUrl":"10.11124/JBIES-24-00376","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to assess and synthesize the existing literature on the effectiveness and safety of intranasal fentanyl versus no intervention, placebo, non-pharmacological, or pharmacological interventions for pain management in infants aged 0-6 months.</p><p><strong>Introduction: </strong>Pain management in infants, especially given their exposure to frequent painful procedures, is a crucial concern. The potential benefits of intranasal fentanyl are notable, but comprehensive guidelines for its use in infants is lacking.</p><p><strong>Eligibility criteria: </strong>This review will include experimental and non-experimental quantitative studies comparing intranasal fentanyl, at any dose/frequency, for pain management in infants aged 0-6 months, against comparators such as no intervention, placebo, or other pharmacological and non-pharmacological interventions. Procedures will include those considered to be tissue-breaking, needle-related, non-tissue-breaking, or any procedure deemed to be painful. The primary outcome will be pain intensity during procedures, chosen for its relevance in evaluating the effectiveness of intranasal fentanyl. Secondary outcomes will include pain response, recovery, frequency of repeated dosing, and safety. Studies in any language will be considered.</p><p><strong>Methods: </strong>This review will adhere to the JBI methodology for systematic reviews and the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. A 3-step search strategy will be used to search databases (Cochrane Library, MEDLINE, Embase, CINAHL, Scopus) without date restrictions. The search results will be reported in a PRISMA flow diagram. Two independent reviewers will extract detailed data on participants, methods, interventions, and outcomes. Certainty will be assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) and JBI appraisal tools to evaluate study quality and bias risk. Data synthesis will combine findings using statistical models, or narrative summaries when meta-analysis is not feasible.</p><p><strong>Review registration: </strong>PROSPERO CRD42024551524.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":"1457-1471"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of selective COX-2 inhibitors in tonsillectomy patients: a systematic review protocol.","authors":"Sophie Dunmall, Lucylynn Lizarondo, Romy Menghao Jia, Eng Hooi Ooi","doi":"10.11124/JBIES-24-00381","DOIUrl":"10.11124/JBIES-24-00381","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to assess the safety of selective cyclooxygenase-2 (COX-2) inhibitors in tonsillectomy patients.</p><p><strong>Introduction: </strong>Recovery after tonsillectomy is painful and requires robust multimodal analgesia to manage; however, there is a risk of bleeding with nonsteroidal anti-inflammatory drugs (NSAIDs). Selective COX-2 inhibitors are theoretically safe due to minimal COX-1 antiplatelet effect; however, their safety as a subclass of medication in tonsillectomy patients has not been well established despite multiple published experimental studies.</p><p><strong>Eligibility criteria: </strong>The review will consider studies that assess patients of any age undergoing tonsillectomy or adenotonsillectomy, treated with an NSAID that is more selective for COX-2 than COX-1. The primary relevant outcome is the incidence of post-tonsillectomy bleeding.</p><p><strong>Methods: </strong>The review will follow the JBI methodology for systematic reviews of effectiveness. The search strategy will include searches of CINAHL (EBSCOhost), the Cochrane Library, Embase (Ovid), MEDLINE (Ovid), SciELO, and Web of Science Core Collection. Studies will be assessed by 2 reviewers independently against the eligibility criteria. Studies of any date, language, or methodological quality may be included for data extraction. The standard JBI methodology for critical appraisal will be used. Effect sizes will be expressed as odds ratios, and subgroup analyses will be used to identify and manage differences in study design and patient cohorts. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach for grading certainty of evidence will be followed.</p><p><strong>Review registration: </strong>PROSPERO CRD42024577071.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":"1434-1440"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of silver diamine fluoride application with atraumatic restorative treatment in arresting the progression of dental caries in children and adults: a systematic review and meta-analysis.","authors":"Anju Varughese, Chandrashekhar Janakiram, Vineetha Karuveettil, Anju James","doi":"10.11124/JBIES-24-00299","DOIUrl":"10.11124/JBIES-24-00299","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This systematic review aimed to evaluate the effectiveness of the application of silver diamine fluoride (SDF) with atraumatic restorative treatment (ART) in arresting the progression of dental caries in cavitated primary or permanent teeth compared with any other caries-arresting treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Dental caries is the most prevalent oral disease globally. Patient-friendly, minimally invasive therapeutic interventions are needed to prevent caries progression and restore cavitated caries lesions cost-effectively. This review assessed the effectiveness of the silver diamine fluoride with atraumatic restorative treatment (SDF-ART technique) in cavitated primary and permanent dentition.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Eligibility criteria: &lt;/strong&gt;Participants of any age with cavitated dental caries lesions in either coronal or root caries of primary or permanent teeth according to International Caries Detection and Assessment System criteria were included. Tooth restoration with direct pulp capping was excluded. Eligible randomized controlled trials included primary or permanent teeth treated with the SDF-ART technique compared with a control, such as SDF application only, ART only, restoration using composite or topical application of other fluoride, placebo, or no interventions. The primary outcome assessed was caries arrest.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The review details were registered in PROSPERO, following which a primary search was conducted in MEDLINE (Ovid), Scopus, Cochrane Central Register of Controlled Trials, Dentistry and Oral Sciences Source, CINAHL (EBSCOhost), Web of Science Core Collection, ProQuest Dissertations and Theses, and Google Scholar. The search date was from January 2016 until March 31, 2024. Data were extracted from included studies regarding the main outcome variable: caries arrest. Critical appraisal was done by 2 independent reviewers to evaluate methodological quality using the JBI Critical Appraisal Checklist for Randomized Controlled Trials. The random-effects model was employed in meta-analysis. The certainty of the evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, and a Summary of Findings was created.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;After removal of duplicates, 638 records were retrieved from the databases. After screening against the eligibility criteria, 7 studies were selected for narrative synthesis after meeting the eligibility criteria requirements. A total of 611 children between 3 and 13 years were included for descriptive analysis. A meta-analysis of 4 studies, with a total sampling unit of 1085 teeth, showed no significant difference in clinical effectiveness of SDF-ART compared with ART alone for caries arrest at 12-month recall (odds ratio 0.84; 95% CI 0.64, 1.11; P =0.215), and the evidence was graded very low. Similarly, pooled results from 2 studies with a sample size of 879 teeth at","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":"1286-1307"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Systematic Review Club: an overwhelmingly successful strategy for workload and technical support during the systematic review process.","authors":"Robyn A Clark, Joyce Ramos, Orathai Suebkinorn","doi":"10.11124/JBIES-25-00219","DOIUrl":"10.11124/JBIES-25-00219","url":null,"abstract":"","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":"23 7","pages":"1510"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of respiratory rehabilitation programs for people with Parkinson's disease: a scoping review.","authors":"Ricardo Filipe de Moura Loureiro, Elaine Dos Santos Santana, Filipa Margarida Gonçalves Duque, Rafael Alves Bernardes, Filipa Isabel Quaresma Ventura, Rosa Carla Gomes da Silva, Albertina Lima de Oliveira, Margarida Pedroso de Lima, Maria de Lurdes Ferreira de Almeida, Daniela Filipa Batista Cardoso, Ana Filipa Dos Reis Marques Cardoso","doi":"10.11124/JBIES-24-00183","DOIUrl":"10.11124/JBIES-24-00183","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this review was to map the characteristics of respiratory rehabilitation programs for people with Parkinson's disease.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Parkinson's disease is a progressive and heterogeneous neurodegenerative disease. Respiratory dysfunction is highly prevalent in people with Parkinson's disease and is a major contributor to morbidity and mortality. People with Parkinson's disease may experience respiratory dysfunction such as ineffective coughing and dyspnea. Complications, such as atelectasis and respiratory infections, significantly impact their self-care and quality of life. To mitigate its impact on people's lives, various respiratory rehabilitation programs have been developed and implemented. Many studies have examined this topic, yet respiratory rehabilitation programs vary significantly in structure and evaluated outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Eligibility criteria: &lt;/strong&gt;We considered studies focused on respiratory rehabilitation programs implemented to prevent or target one or more symptoms for adults (18 years and older) with Parkinson's disease, regardless of the disease stage. The programs could be provided by any health professional in any health care setting.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We followed JBI methodology for conducting the scoping review, and the results were reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR). A literature search was conducted across PubMed, CINAHL Complete (EBSCOhost), Cochrane Central Register of Controlled Trials (EBSCOhost), the Cochrane Database of Systematic Reviews (EBSCOhost), Scielo, Scopus, PEDro, and ClinicalTrials.gov. Unpublished studies were identified via Google Scholar, DART-Europe, and MedNar. All search strategies were conducted on April 24, 2023. Sources published in English, Spanish, and Portuguese were included and no date restrictions were applied. Study selection and data extraction were conducted independently by 2 reviewers using a standardized extraction tool.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Thirty-three studies published between 2001 and 2023 were included. Studies were conducted in the USA, Brazil, Turkey, Chile, Australia, Taiwan, Czechia, Italy, Republic of Korea, Germany, India, and Israel. The sample sizes ranged from 1 participant to 75 participants. The combined sample size of all studies was 1007 participants. Most programs integrated respiratory muscle strength training using devices, targeting people with Parkinson´s disease in Hoehn and Yahr scale stages 1-3. Speech-language pathologists, physiotherapists, and medical doctors were the health professionals responsible for delivering these programs in home-based or clinical settings. A broad spectrum of outcomes related to respiratory function was reported. Additionally, the studies assessed other outcomes such as quality of life, functional capacity, motor symptoms, an","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":"1308-1375"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of manual techniques, exercise therapy, or combined treatments in the management of ankle sprains or chronic ankle instability in adult athletes: a systematic review protocol.","authors":"Stéphanie Grosdent, François Léonard, Christophe Demoulin, Aude Aguilaniu, Benjamin Hidalgo, Nancy Durieux","doi":"10.11124/JBIES-24-00057","DOIUrl":"10.11124/JBIES-24-00057","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review will be to synthesize the evidence on the effectiveness of manual techniques, exercise therapy, or combined treatments in the management of ankle sprains and chronic ankle instability in adult athletes.</p><p><strong>Introduction: </strong>Acute ankle sprains and chronic ankle instability are common in athletes. These conditions can result in varying degrees of disability, including reduced athletic performance and time out of competition, which may have adverse psychological effects.</p><p><strong>Eligibility criteria: </strong>The review will consider randomized controlled trials evaluating the effectiveness of manual techniques and/or exercise therapy for ankle sprain or chronic ankle instability in adult athletes. The comparators will include sham treatment, no treatment, and other conservative interventions. The outcomes of interest will be pain intensity, functional disability, ankle joint range of motion, ankle muscle strength, postural control, and subjective stability.</p><p><strong>Methods: </strong>The review will follow the JBI methodology for systematic reviews of effectiveness. Searches will be conducted to locate published and unpublished studies in the following sources: MEDLINE (Ovid), CENTRAL (Ovid), Embase, SPORTDiscus (EBSCOhost), Physiotherapy Evidence Database (PEDro), Google Scholar, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform (ICTRP). Two independent reviewers will select the studies, critically appraise them, and extract data. Then, a narrative synthesis and, if appropriate, a meta-analysis will be performed. The certainty of findings will be determined using the GRADE approach.</p><p><strong>Review registration: </strong>PROSPERO CRD42023493687.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":"1501-1509"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validated geographic search filters for bibliographic databases: a scoping review.","authors":"Catharina Muente, Alexander Pachanov, Julian Hirt, Lynda Ayiku, Dawid Pieper","doi":"10.11124/JBIES-24-00395","DOIUrl":"https://doi.org/10.11124/JBIES-24-00395","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The purpose of this scoping review was to identify validated geographic search filters and report on their development and performance measures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The number of scientific publications has considerably increased. Measures to limit the search and screening efforts can be helpful to increase the efficiency of preparing systematic reviews. Search filters are useful tools for reviewers to identify reports with a common characteristic in bibliographic databases. Geographic search filters limit literature search results to a specific geographic characteristic (eg, a country or region). Searching the literature using geographic filters can be useful to find evidence about health care practices in distinct geographic regions; provide an overview of cultural, epidemiological, or health economics aspects; or to indicate inequalities in health care in a certain region. Our aim was to identify validated geographic search filters and report on their development and performance measures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Inclusion criteria: &lt;/strong&gt;We included reports on validated geographic search filters aiming to identify research from or about defined geographic features (eg, countries/regions or groups of them) with no restriction regarding the time frame and language of publication.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This review was conducted in accordance with JBI methodology for scoping reviews and its methods were pre-specified in an a priori protocol. We searched PubMed, Embase (Elsevier), The InterTASC Information Specialists' Sub-Group (ISSG) Search Filter resource, and Google Scholar. The study selection process was independently conducted by 2 reviewers, encompassing both abstract and full-text screening. The data extraction included basic characteristics of the geographic search filter (eg, country/region, database), methods used to develop and validate the search filters, and their performance measures. The extracted data are tabulated and summarized narratively.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Our literature search yielded 907 hits. We included 9 reports that addressed 6 search filters for a broad range of geographic regions, including Spain, the African continent, the United Kingdom, the United States, OECD countries as a group, as well as publications in high-ranking nursing journals from countries where German is spoken. The methods used for developing geographic search filters were heterogeneous. Gold standard sets were created by database searching (n = 3; 50%) and relative recall (n = 3; 50%). Only 3 filters were created using objective methods and 2 underwent internal validation. The sensitivity of the search filters ranged from 73% to nearly 100%.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The findings show that validated geographic search filters are not widely available. The identified search filters may serve as methodological outlines for the development of search filters for other countries or g","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health care worker trust in the health care system, pre- and post-COVID-19 pandemic: a scoping review protocol.","authors":"Nickolas J Cherwinski, Lorelei Newton, Lenora Marcellus, Bernadette Zakher, Jessica Mussell","doi":"10.11124/JBIES-24-00371","DOIUrl":"https://doi.org/10.11124/JBIES-24-00371","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this scoping review is to identify the team, leadership, and organizational characteristics, behaviors, and traits that have created or reduced health care worker trust in the health care system, pre- and post-COVID-19 pandemic; and to categorize the findings using the health care ecosystem as a descriptive framework (ie, teams, leadership, organizations, systems).</p><p><strong>Introduction: </strong>Trusting relationships and trustworthy organizational cultures promote employee well-being, satisfaction, and retention. High levels of trust are associated with ethical and just workplaces as well as high-functioning organizations with enhanced patient experiences. Emerging trust research in a post-pandemic climate correlates high health care worker trust with higher levels of patient trust, suggesting contributions to healthier workplaces and improved patient outcomes.</p><p><strong>Inclusion criteria: </strong>The population is health care workers, the concept is trust, and the context is the health care system. We will consider all health care workers in any health care setting, in any country, or position. All relevant published and unpublished studies will be considered, with no date or language limitations, including all primary studies, gray literature, and textual papers.</p><p><strong>Methods: </strong>This review will foll ow the JBI methodology for scoping reviews, including the JBI approach to critical appraisal, study selection, data extraction and data synthesis. Two reviewers will independently extract data from selected papers using a standardized tool modified for the review. Results will be presented using frequency tables, accompanied by a narrative summary.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral hygiene care and the management of oral symptoms in patients with cancer in palliative care: a mixed methods systematic review.","authors":"Ricardo Serra, Sofia Roque, Helena Arco","doi":"10.11124/JBIES-24-00204","DOIUrl":"10.11124/JBIES-24-00204","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this review was to examine the effectiveness of oral hygiene care for the management of oral symptoms in patients with cancer receiving specialist palliative care and the patients' experience of oral symptoms and oral hygiene care.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Oral symptoms, such as xerostomia, mouth pain, or dysgeusia, are highly prevalent in patients with cancer receiving specialist palliative care. These symptoms negatively affect patients' quality of life. Oral hygiene care can assist in the management of oral symptoms. This care could be improved with a more systematic approach, adequate guidelines, and training to properly integrate it into the care provided by specialist palliative care teams.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Eligibility criteria: &lt;/strong&gt;This review considered quantitative, qualitative, and mixed methods studies on oral hygiene care for the management of oral symptoms in adult patients with cancer, aged 18 years or older, diagnosed with any type of cancer, receiving specialist palliative care. For the quantitative component, eligible studies measured the effectiveness of oral hygiene care, of any frequency or duration, using any valid method, for the management of oral symptoms; oral hygiene care interventions were compared with standard care, another experimental care, or no comparison. For the qualitative component, eligible studies explored participants' experiences of oral symptoms and the provision of oral hygiene care. Specialist palliative care was provided in several settings, including palliative care units, inpatient hospice, home palliative care teams, or day care centers.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The search was conducted in PubMed (NLM), CINAHL Complete (EBSCOhost), Cochrane Central Register of Controlled Trial, Dentistry and Oral Sciences Source (EBSCOhost), and MedicLatina (EBSCOhost). Sources of unpublished studies and gray literature searched included Networked Digital Library of Theses and Dissertations and Repositórios Científicos de Acesso Aberto de Portugal. Studies in English, Portuguese, and Spanish from 2000 to October 2023 were considered. Methodological quality was assessed and data were extracted by 2 reviewers. Synthesis and integration followed the JBI convergent segregated approach for mixed methods reviews. Meta-analysis of quantitative studies was not possible and findings were reported narratively. Meta-aggregation was used to pool findings of qualitative studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Six studies (2 randomized controlled trials, 2 quasi-experimental studies, and 2 qualitative studies) were included, involving 451 participants. Studies that had a methodological quality of 75% or higher, based on affirmative answers in the respective critical assessment tool, were included in the review. Evidence indicated that oral hygiene care may be effective for the management of oral symptoms. Patients reported a reduction in oral symptoms, such as ","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of conditional cash transfers for uptake and retention in HIV prevention of mother-to-child transmission services in low- and middle-income countries: a systematic review and meta-analysis.","authors":"Mamuye Hadis, Tesfaye Dagne, Sabit Ababor, Dagmawit Solomon, Samson Mideksa, Zelalem Kebede, Yosef Gebreyohannes, Firmaye Bogale","doi":"10.11124/JBIES-24-00099","DOIUrl":"10.11124/JBIES-24-00099","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this systematic review was to synthesize the best available evidence on the effectiveness of conditional cash transfers for the uptake and retention in the prevention of mother-to-child transmission (PMTCT) services in pregnant and/or breastfeeding women with HIV infection in low- and middle-income countries (LMIC).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Regardless of the effectiveness of PMTCT services, uptake, and retention in such services remains poor in LMIC. Conditional cash transfers are considered an important strategy to improve the uptake of preventive services in pregnant women and children. This review evaluated the effectiveness of conditional cash transfers in improving uptake and retention in the PMTCT services for pregnant and/or breastfeeding women with HIV infection.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Inclusion criteria: &lt;/strong&gt;Studies that compared the impact of conditional cash transfers on uptake and retention in the prevention of mother-to-child services with standard care or with another intervention in pregnant and/or breastfeeding women with HIV were considered for inclusion. The primary outcomes of this review were retention and uptake of pregnant women with HIV in PMTCT programs, reported as the percentage of pregnant and/or breastfeeding women with HIV enrolled in antiretroviral therapy; and the number of facility-based deliveries. The secondary outcomes included the percentage of infants completing post-exposure HIV testing at 4 to 6 weeks after birth or early infant diagnosis; the percentage of infants exposed to HIV testing positive for HIV; and the percentage of infants exposed to HIV with health defects (eg, neural tube defects, heart defects, major limb malformations).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Databases searched included: Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase (Ovid), and CINAHL (EBSCOhost). Sources of unpublished studies/gray literature included ProQuest Dissertations and Theses, OpenGrey, WHO International Clinical Trials Registry Platform, and Clinical-Trials.gov. Studies published in English since 2000 were considered. The JBI Critical Appraisal Checklist for Randomized Controlled Trials was used to assess the methodological quality of the included studies. Data were extracted from the included studies and studies were pooled in a statistical meta-analysis. Effect sizes were presented as odds ratios (OR) and CI (95%) were calculated. The standard χ2 and I2 tests were used to assess heterogeneity statistically. Statistical analyses were conducted using fixed effects based on established guidance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Two randomized controlled studies were included in this review with a total of 950 participants. Two outcomes were pooled and assessed for the effects of conditional cash transfer: facility-based delivery and early infant diagnosis. Conditional cash transfer has significant positive effects on both outcomes compared to ","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}