Middle East Journal of Rehabilitation and Health最新文献

{"title":"Ozone Decreases Biomarkers of Inflamation (C-Reactive Protein and Erytrocyte Sedimentation Rate) and Improves Pain, Function and Quality of Life in Knee Osteoarthrtitis Patients: A Before-and-After Study and Review of the Literature","authors":"M. E. Fernández-Cuadros, O. Pérez-Moro, M. Albaladejo-Florín, Ruben Algarra-López","doi":"10.5812/MEJRH.64507","DOIUrl":"https://doi.org/10.5812/MEJRH.64507","url":null,"abstract":"Objectives: Theaimof thisstudywastoevaluateif ozoneiscapableof decreasingbiomarkersof inflammation(CRP/ESR)andpain, and to improve function and quality of life in knee osteoarthrtitis (OA) patients. Methods: Aprospectivequasiexperimental(before-and-afterstudy)researchwasperformedtoinvestigatetheeffectof Ozonether-apyprotocol. Theinterventionincluded4sessions(1session/week)of anintra-articularinfiltrationof amedicalmixtureof Oxygen-Ozone (95% to 5%) at 20 ug/mL concentration. Biochemical evaluation (CRP and ESR), pain VAS, and WOMAC scales were evaluated before and after the treatment. Results: Overall, 33 patients were evaluated. Mean age was 68.18 ± 8.43 years. Female patients accounted for 75.7% (n = 25) and male patients corresponded to 24.3% (n = 8). Female: male ratio was 3:1. The most frequent radiological KL grade was 2º (n = 22, 66.7%), followed by3º (n = 8, 24.2%), and 4º (n = 3, 9.1%). Biomarkersof inflammation decreased significantly. C-reactive protein (CRP) diminished from 0.33 ± 0.32 mg/dL to 0.25 ± 0.23 mg/dL (P = 0.0456). Erythrocyte sedimentation rate (ESR) decreased from 15.06 ± 12.09 mm/h to 11.81 ± 8.32 mm/h (P = 0.01). Before treatment, pain measured by VAS was 7.33 ± 1.31 points and decreased to 2.84 ± 1.76(P=0.0000). TheWOMAC-painsubscalewas14.84 ± 2.77pointsanddiminishedto5.96 ± 3.53(P=0.0000), WOMACstiffness subscale was 3.06 ± 1.95 points and ameliorated to 1.15 ± 1.3 (P = 0.0000), WOMAC-function subscale was 41.15 ± 12.58 points and decreased to 22.3 ± 11.64 (P = 0.000). Conclusions: Ozoneiscapableof bothdecreasingpainandstiffnessandimprovingfunctionandqualityof lifeinkneeOApatients, yet decreases biomarkers of inflammation, such as CRP and ESR. inflammation hypothesized stiff-nessandQoL,andmanystudiessuggestthatozoneiscapa- bleof amelioratinginflammation(5). Therationaletoeval-uateCRP/ESRisthatinflammationbiomarkersmaypredict outcomes in OA. Elevated hs-CRP predicts loss of cartilage in knee OA and poor results after total knee arthroplasty. acute phase","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47988729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Depression Among Primary Caregivers of Stroke Survivors in Nigeria","authors":"Umeonwuka Chuka Ifeanyi, Fatimah Sa'ad, Ogbueche Chukwudi Martin, Maduagwu Stanley Monday, Nwachukwu Juliet Onyinyechukwu","doi":"10.5812/MEJRH.65080","DOIUrl":"https://doi.org/10.5812/MEJRH.65080","url":null,"abstract":"Background: Stroke has a great adverse effect not only on the lives of stroke survivors but also on the informal caregivers, as they provide care ranging from assistance in activities of daily living, leading to a high risk of depression and other psychological morbidities. Objectives: This study explored the prevalence of depression and associated factors among primary caregivers of stroke survivors in Nigeria. Methods: A cross sectional survey on the prevalence of depression among primary caregivers of stroke survivors was conducted at selected hospitals in Maiduguri, Nigeria. A sample of convenience was used to recruit participants in this study. The Beck depression inventory was used to screen for depression. Data form and patients folders were used to obtain socio-demographics and clinical characteristics of participants and stroke survivors. Result: A total of 115 primary caregivers participated, out of which 53% were male and 47% were female. The mean age and overall beck depression inventory score were 30.78 ± 9.66 and 15.42 ± 7.84, respectively. The overall prevalence of depression was found to be 46.1%. Type of stroke (P = 0.03) and post stroke duration (P = 0.02) of stroke survivors cared for was found to be associated with depression among caregivers of stroke survivors. Conclusions: Caring for the patients with stroke presents increased in the psychological impact of caregiving for stroke survivors, it is therefore recommended that information, education, and support should be provided to primary caregivers as they are key in sustaining rehabilitation gains and long term overall well-being of stroke survivors.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45430503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a New Method for Biological Activity Analysis of Recombinant Human Parathyroid Hormone-Related Protein","authors":"D. Nasrabadi, Siamak Rezaeiani, Ali Sayadmanesh, M. Gharaati, M. B. Eslaminejad, A. Shabani","doi":"10.5812/MEJRH.65828","DOIUrl":"https://doi.org/10.5812/MEJRH.65828","url":null,"abstract":"Background: BaParathyroid hormone-related protein (PTHrP) is a multi-functional protein with a sequence “aa 1-34” similar to that of parathyroid hormone (PTH). In spite of growth factor activity, there is no standardized analytical method to determine the biological activity of recombinant PTHrP. Methods: The current study isolated the cDNA encoding 141 N-terminal amino acid sequence of PTHrP, cloned it in plasmid vec-tor pET32a, and produced recombinant PTHrP in Escherichia coli . The biological activity analysis of the recombinant protein was evaluated using a precise and practical method that measured PTHrP-mediated cell proliferation of a breast cancer cell line MCF7. Additionally, to investigate the accuracy and precision of MCF-7 method used, chondrogenic differentiation condition of PTHrP treated mesenchymal stem cells (MSCs) was evaluated. Results: DNAsequencingand protein massspectrometryanalysisconfirmedtheaccuracy of clonedcDNAsequenceandexpressed the protein. Biological activity analysis showed the increasing effect of recombinant PTHrP on cell proliferation of cancer cell line MCF-7. Alkaline phosphatase and gene expression analysis validated the anti-hypertrophy effects of recombinant PTHrP on chondrogenic differentiation of MSCs. Conclusions: The current study method removed potential challenges and errors in comparability and reproducibility studies focusing on stem cell differentiation and pathogenesis of breast cancer arising from PTHrP biological activity analysis.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43715077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimized Storage Methods of RNA Extraction from Formalin Fixed Paraffin Embedded Tissue","authors":"Mehdi Barati, M. S. Barough, F. Pak, V. Semnani, Mehrnoosh Pashaei, P. Kokhaei","doi":"10.5812/MEJRH.63356","DOIUrl":"https://doi.org/10.5812/MEJRH.63356","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47206646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Low Back Pain in Young Population: An MRI Study","authors":"E. Ekin, M. E. Altunrende","doi":"10.5812/MEJRH.64143","DOIUrl":"https://doi.org/10.5812/MEJRH.64143","url":null,"abstract":"Background: Low back pain is a common health problem in the younger population. Spinal degeneration is the most common cause of low back pain. Objectives: The purpose of this study was to investigate the most common causes of low back pain with MRI in young people under the age of 40 and to determine gender differences, if any. Methods: This is a retrospective study on 200 consecutive patients between the ages of 17 39 who had lumbar MRI (1.5 T MRI). Patients were included in the study based on the information collected from the radiological database system and neurosurgical clinical archives between September October 2017. Spinal mass, spondylolisthesis, disc degeneration, multifidus muscular atrophy, and congenital anomalies were investigated. Studied parameters were compared in male and female patients. Results: Disc degeneration or hernia was observed in 132 patients (66%) and no gender difference was found for a disc hernia (P = 0.376 Chi-Square test). The most frequent disc hernia was detected at the level L5 S1. Multifidus muscular atrophy was identified in 54 (27%) of all patients and it was higher in women (P < 0.001, Chi-Square test). Accepted change of lumbar lordosis was detected only in 10 patients. Conclusions: Disc herniation is the most common causes of low back pain in young people under the age of 40 and there are no gender differences.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44373741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and Validity of Sedentary Behavior Questionnaire in Turkish Population: Evaluation of Psychometric Properties","authors":"Y. Bakar, A. Tuğral, A. Ozel, Y. D. Altuntaş, Y. Yakut","doi":"10.5812/MEJRH.63576","DOIUrl":"https://doi.org/10.5812/MEJRH.63576","url":null,"abstract":"Background: Inactivityandsedentarylifestyleareawell-knownriskfactorsforhealtheffects. Manyquestionnairesevaluatephysi-calactivity(PA)level;however,theevaluationof sedentarybehaviorneedsmoreattention. Sedentarybehaviorquestionnaire(SBQ) isareliable,valid,andeasy-to-administertool. Thecurrentstudyaimedatcross-culturallyadaptingandassessingthereliabilityand validity of the Turkish version of SBQ. Methods: SBQ consists of 9 items related to sedentary lifestyle both on weekdays and weekends. SBQ was administrated to 235 participantswiththeattritionrateof 24%,followedbyarepeatedadministrationafter7daystoassessitsreliability. Criterion-related validitywasanalyzedwiththeinternationalphysicalactivityquestionnaire-shortform(IPAQ-SF)withintheconstructvalidityof the SBQ.Test-retestreliabilitywasassessedbytheintraclasscorrelationcoefficient(ICC),whiletheSpearmanrhowasusedforcriterion-related validity. Results: The ICC scores for each parameter ranged from 0.388 to 0.771. The obtained results showed moderate to good test-retest reliability. The validity results of SBQ somewhat violated the standards, which are generally accepted. Items of SBQ “watching TV (includingvideosonVCD/DVD)”,“sittingandtalkingonthephoneorbeingbusyonthephone”,and“doingpaperworkorcomputer work (office work, e-mails, paying bills, etc.)” correlated significantly with body mass index (BMI) (r = -0.138 to 0.247, P < 0.05). Conclusions: The SBQ had good reliability and acceptable validity to assess sedentary behaviors in a Turkish population.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49037257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Ultrasound on Musculoskeletal Pathology in Hands of a Rehabilitation Specialist: A Review of the Literature","authors":"M. E. Fernández-Cuadros, O. Pérez-Moro, M. Albaladejo-Florín, Carmen Ramos-Gonzalez, Laura Cabrera-Rodriguez, Ruben Algarra-López","doi":"10.5812/MEJRH.65931","DOIUrl":"https://doi.org/10.5812/MEJRH.65931","url":null,"abstract":"Musculoskeletal (MSK) disorders are very prevalent in a rehabilitation setting. These disorders involve muscle, tendon, ligaments, as well as nerves, and are related to overuse due to work or sports, and degeneration due to aging. These conditions are usually diagnosedbasedonclinicalsignsandsymptoms;however,amoreaccuratediagnosisisrequired. Theimagingtechniquesfordiag-nosis include radiography, magnetic resonance imaging (MRI), and ultrasounds (US). In this review article, US is proposed to be an effective technique in diagnosing MSK pathologies, which, in hands of a Rehabilitation specialist, constitute a dynamic, accurate, economic, and cost-effective tool.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43106090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Walking with Aids on Walking Speed and Selected Cardiovascular Parameters in Apparently Healthy Elderly Individuals","authors":"C. B. Aiyejusunle, A. Akodu, Oluwadamilola Jarinat Giwa","doi":"10.5812/MEJRH.62803","DOIUrl":"https://doi.org/10.5812/MEJRH.62803","url":null,"abstract":"Background: Elderly individuals make up a large part of the population, many of whom use walking aids and also tend to have a higher percentage of cardiovascular complications. There is a need to document the effects of walking with different aids on walking speed and selected cardiovascular parameters. Objectives: Thisstudyaimedatdeterminingandcomparingtheeffectsof walkingwithcane,tripod,andwalkingframeonwalking speed and selected cardiovascular parameters in apparently healthy elderly individuals. Methods: Thirty-five (35) elderly individuals participated in this study. Participants’ systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured after ambulation with and without walking aids. Walking speed (WS) was measured as each participant walked at their normal comfortable pace without aid and with 3 walking aids on separate days. Analysis of variance (ANOVA) was used to find a significant difference between variables. Results: Participants’ meanagewas74.89 ± 7.15years. Systolicbloodpressure(SBP)(138.57 ± 16.62mmHg),diastolicbloodpressure (DBP),(80.37 ± 9.57mmHg),andheartrate(HR)(75.51 ± 9.54beats/min)afterwalkingframeambulationwerehigherthanwithcane (132.91 ± 18.97 mmHg; 78.74 ± 8.59 mmHg; 75.37 ± 10.28 beats/min) and tripod (130.40 ± 16.59 mmHg; 77.31 ± 9.13 mmHg; 74.63 ± 9.92beats/min)ambulation,respectively. Walkingspeed(0.58 ± 0.21m/s)withacanewassignificantlyhigher(P=0.001)thanwith frame (0.31 ± 0.12 m/s), and tripod (0.50 ± 0.19 m/s). Conclusions: Walking frame ambulation elicited a higher blood pressure, a higher HR and a slower WS than cane and tripod ambulation, respectively. The participants walked significantly faster with a cane than tripod and walking frame.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41568912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and Challenges Experienced by Seniors in Using Online Social Networks: A Phenomenological Study","authors":"Marjan Momeni, N. Hariri, Monir Nobahar, F. Noshinfard","doi":"10.5812/MEJRH.65310","DOIUrl":"https://doi.org/10.5812/MEJRH.65310","url":null,"abstract":"Background: Many studies have indicated that the use of social networks and online communication by seniors can improve their general health and social welfare as well as promote the quality of their lives. However, problems with the use of online social networks may prevent them from using the networks. This study aims to explain the experiences of older adults when facing barriers and challenges of using social networks. Methods: This qualitative study takes a phenomenological approach and was carried out in 2016 using purposive sampling. We collected the in-depth semi-structured interviews with 9 seniors) 3 males and 6 females) with an average age of 68.3 years. Subjects confirmed to be active members in at least 1 of the online social networks. The data were analyzed using Colaizzi’s 7-step method. Results: Two main themes of “preconditions of use” and “individual concerns” were extracted from the data analysis. A total of 6 relevant subthemes were as follows: “need for equipment and facilities,” “adequate income”, “need for technical knowledge”, “trust in information”, “trust in other users”, and “security and privacy”. Conclusions: People of older age reported barriers and difficulties using online social networks. It seems that the elderly can be encouraged to use these social networks and improve the quality of their lives through educational planning.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48328422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Sublingual Misoprostol and Intravenous Oxytocin in the Management of Postpartum Hemorrhage After Cesarean Delivery: A Randomized Controlled Trial","authors":"N. Rahbar, Neda Mirjan, R. Ghorbani","doi":"10.5812/MEJRH.62025","DOIUrl":"https://doi.org/10.5812/MEJRH.62025","url":null,"abstract":"Background: Postpartumhemorrhage(PPH)isoneof themostimportantcausesof maternalmorbidityandmortality. Ithasbeen accepted that an effective way for preventing PPH is active management of third stage of labor. Objectives: Thisstudyaimedatfindingtheeffectof 800 µ gofsublingualmisoprostolcomparedto60unitsofintravenousoxytocin in Ringer-lactate to reduce PPH after cesarean delivery. Methods: This single blind randomized clinical trial was conducted at Amir Al-Momenin hospital in Semnan, Iran, from June 2013 to April 2014. A total of 100 pregnant (Gravidity 1, 2) women entered the study. They were randomized into 2 groups. One group received800 µ gsublingualmisoprostol(n=50)andtheothergroupreceived60IUoxytocinintravenously(n=50)inthecesarean section under spinal anesthesia, immediately after the opening of the peritoneum. Results: The mean ± SD decline in hematocrit level after 24 hours of delivery was 2.6% ± 2.3% in misoprostol group and it was 3.2% ± 2.5% in oxytocin group, and the difference was not significant (P = 0.27). The need for the additional uterotonic drug was significantly higher in the oxytocin group (16%) than in the misoprostol group (2.1%) one hour after delivery (P = 0.031). During one hour after delivery, the incidence of shivering was significantly lower in oxytocin group (P = 0.001), but on the contrary, the incidence of hypotension in the oxytocin received patients was higher (P = 0.003). Conclusions: The effectiveness of sublingual misoprostol is similar to intravenous oxytocin in reducing cesarean section hemorrhage. Moreover,becauseshiveringasanuntreatableadverseeffectof misoprostolwasverybothersomeforthepatients,werecom-mend that sublingual misoprostol not be used in high dosage.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46355692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}