Middle East Journal of Rehabilitation and Health最新文献

{"title":"Letter to “Comparing the Lifestyle and Sexual Satisfaction of Patients Received Methadone Maintenance Therapy with Those of Patients Received and Narcotics Anonymous”","authors":"Saeid Komasi","doi":"10.5812/MEJRH.80738","DOIUrl":"https://doi.org/10.5812/MEJRH.80738","url":null,"abstract":"Letter to “Comparing the Lifestyle and Sexual Satisfaction of Patients Received Methadone Maintenance Therapy with Those of Patients Received and Narcotics Anonymous” Saeid Komasi * Lifestyle Modification Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Corresponding author: Saeid Komasi, Lifestyle Modification Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Zakarya Razi Blvd., Kermanshah, Iran, Tel/Fax: +98-8334276299, E-mail: s_komasi63@yahoo.com","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47340737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Divided Attention Dysfunction in Alzheimer’s Disease","authors":"S. S. Mirahadi, Seyyed Ahmad Reza Khatoonabadi, Fatemeh Fekar Gharamaleki","doi":"10.5812/MEJRH.64738","DOIUrl":"https://doi.org/10.5812/MEJRH.64738","url":null,"abstract":"Context: Divided attention is impaired in the early stages of Alzheimer’s disease (AD). The influence of divided attention on people with AD has been considered from different perspectives, such as motor ability, cortical responses, performance in divided attention evaluation tasks, and comparison of divided attention and directed and focused attention. The purpose of the current study was to investigate divided attention in AD patients from these different perspectives. Evidence Acquisition: An electronic search was performed in January and February 2016 in PubMed, Science Direct, Medline, Scopus, Google Scholar, and Ovid databases to obtain relevant articles published from 1980 to 2015. The keywords used included “Alzheimer’s disease”, “attention”, and “divided attention”. The articles obtained were studied using the following standard protocol for inclusion criteria written in the English language, the focus of studies was on divided attention in AD, and no other types of cognitive ability. From the 60 articles found, 10 articles that were adhered to the inclusion criteria were selected for consideration. Results: The 10 studies reviewed considered divided attention in AD from different domains. These domains showed that AD patients had impaired performance in tasks that required divided attention and showed deficits in motor tasks stemming from the negative effects of impaired divided attention on motor ability. Different types of brain deficits have been observed in neuroimaging techniques in individuals with AD during divided attention tasks. Those with AD showed greater impairment for divided attention than for directed and focused attention. Conclusions: Divided attention influences the lives of those with AD from several perspectives. These include the inability to focus on two or several relevant stimuli simultaneously that require divided attention rather than directed and focused attention and a deficit in the performance of motor tasks such as gait and other problems in daily life, such as falling. In addition, depression also had a negative effect on divided attention. Depressed AD patients had more difficulty in daily activities than AD patients without depression. The areas of the brain involved in divided attention in individuals with AD differ from those involved in unaffected people.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43957783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Work-Family Conflict and Job Satisfaction of Medical Staff after Implementing the Health System Development Plan","authors":"H. Habibian, Masoudeh Babakhanian, Gholamreza Mohammadi, Faezeh Deljo, Zeinab Safarian Moradabad, Nasrin Rezazadeh Darvishbaghal, M. Asadian","doi":"10.5812/MEJRH.57141","DOIUrl":"https://doi.org/10.5812/MEJRH.57141","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47737960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Job Burnout Among Iranian Speech and Language Pathologists","authors":"Fatemeh Kasbi, Shohre Kaviani, Maryam Mokhlessin, L. Monshizadeh, R. Noruzi, N. Kia","doi":"10.5812/MEJRH.64374","DOIUrl":"https://doi.org/10.5812/MEJRH.64374","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46367184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory Effects of Silica Nanoparticles Loaded with Hematoporphyrin on Breast Cancer Cell Line","authors":"A. Khaleghian, H. Hasanzadeh, Abdolvahab Moshtaghian, Reza Nasr, Alireza Emadi, Shima Moshfegh","doi":"10.5812/MEJRH.64843","DOIUrl":"https://doi.org/10.5812/MEJRH.64843","url":null,"abstract":"Background: Cancer is one of the main causes of death in the world. In recent years, many studies have been conducted on the usage of nanomaterials in cancer treatment. In previous studies, the anti-tumor effects of mesoporous silica nanoparticles (MSN) on cancer cells have been shown. The aim of this study was to evaluate the effect of MSN loaded with Hematoporphyrin (HpD) on the cell proliferation and invasion of MCF7 (Michigan Cancer Foundation-7) breast cancer cell line. The antioxidant effects of MSN loaded with HpD were also investigated. \u0000Methods: In this study, using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay, the proliferation and viability of cancer cells were studied after exposure to MSN loaded with HpD. The wound healing assay technique (migration test) was used for the assessment of cancer cells’ invasion. The antioxidant effects of MSN loaded with HpD were studied by DPPH (2,2-diphenyl-1-picrylhydrazyl) assay and FRAP (ferric reducing/antioxidant power) assay techniques. \u0000Results: Our results showed that the viability and proliferation of breast cancer cell line MCF7 in the presence of silica nanoparticles loaded with hematoporphyrin (HpD) significantly declined (P = 0.02). After exposure to mesoporous silica nanoparticles (MSN) loaded with hematoporphyrin (HpD), the cancer cell invasion decreased (P = 0.025). Silica nanoparticles alone and loaded with hematoporphyrin (HpD) showed considerable cytotoxic activities against cancer cell lines (IC50 = 20 - 30 μg.mL-1). The most promising result was achieved for MSN loaded with hematoporphyrin (HpD) with the minimum IC50 value. It was found that the proliferation rate of MCF7 cells decreased after treatment with this compound in a dose-dependent manner. The assessments with DPPH assay and FRAP assay techniques showed that MSN and MSN loaded with HpD have antioxidant activities. \u0000Conclusions: MSN loaded with HpD have an inhibitory effect on the growth of the MCF7 cell line. MSN alone and in combination with HpD have an inhibitory effect on cell invasion in the MCF7 cell line. MSN alone and loaded with HpD have antioxidant effects. These results indicate that MSN has the potential to be used in cancer treatment as a carrier for anticancer drugs. \u0000Keywords: Silica Nanoparticles; Hematoporphyrin; Cell Viability; Invasion; Antioxidant; Breast Cancer; Cell Line","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49296723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Reality: A Novel Approach in Rehabilitating People with Schizophrenia","authors":"M. Z. Bidaki, S. B. Mousavi","doi":"10.5812/MEJRH.80071","DOIUrl":"https://doi.org/10.5812/MEJRH.80071","url":null,"abstract":": Since the introduction of schizophrenia, different approaches have been developed to ameliorate the symptoms or improve the quality of life in patients who are diagnosed with schizophrenia. Currently, scientists around the world are developing new techniques to treat and rehabilitate people with schizophrenia. One of these techniques is virtual reality, which benefits the patient through simulating the experience of acting in a variety of settings and interacting with virtual characters. In this study, we aimed to briefly introduce this technique to scholars in the field of psychiatry and rehabilitation.","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45892503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction Model for Self-Care Behaviors among Iranian Elders with Chronic Heart Failure","authors":"A. Kamrani, M. Foroughan, J. Charati, Z. Taraghi","doi":"10.5812/MEJRH.69601","DOIUrl":"https://doi.org/10.5812/MEJRH.69601","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46412042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep and Sleep Impairment in Victims of Traumatic Brain Injury","authors":"N. Gadoth","doi":"10.5812/MEJRH.65864","DOIUrl":"https://doi.org/10.5812/MEJRH.65864","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42186620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Vitamin D on Hippocampus Brain-Derived Neurotrophic Factor Level in Chronic Mild Stress Model of Depression in Rats","authors":"Z. Yousefian, A. Khaleghian, Homan Parsaei, Abbas Ali Vafaei, A. Rashidy-Pour, K. Sedaghat","doi":"10.5812/MEJRH.63901","DOIUrl":"https://doi.org/10.5812/MEJRH.63901","url":null,"abstract":"","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48517018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BMI1 as a Potential Target of miR-330-3p in Colorectal Cancer","authors":"Mohammad Hasan Soheilifar, Abdolvahab Moshtaghian, R. Amini, Masoud Asefi, Parviz Basiri, M. Saidijam","doi":"10.5812/MEJRH.66075","DOIUrl":"https://doi.org/10.5812/MEJRH.66075","url":null,"abstract":"Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. CRC therapy is still a serious problem because of the presence of cancer stem cells (CSCs) within the tumor. BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is one of the important molecules for self-renewal of the CSCs and a component of poly comb repressive complex 1 that plays an important role in stimulating the progression of the cell cycle through epigenetic inhibition of tumor suppressors. BMI1 is a marker of colon stem cells that its expression increases in colorectal CSCs. The inhibition of BMI1 expression by miRNA could be one of the promising treatment options in CRC. Furthermore, investigating the regulation of BMI1 expression by miRNAs during tumorigenesis could be valuable in the identification of molecular mechanisms involved in CRC. Our aim was to conduct a bioinformatics analysis of known tumor suppressor miRNAs in CRC that have a potential to inhibit BMI1 expression. \u0000Methods: The presence of BMI-1, as a potential target of the selected miRNAs, was explored in various databases of miRNA target prediction including TargetScan, DIANA-microT, PicTar, miRanada, miRtar, mirMAP, and miRDB. These databases are based on algorithms such as miRNA-target interactions and thermodynamic stability (�G). miRNA with the highest score was selected according to the prediction score. \u0000Results: According to bioinformatics analysis, the highest score was derived for miR-330-3p. As a new miRNA to suppress BMI-1, miR-330-3p can be used in applied studies. \u0000Conclusions: Compared to other tumor suppressor miRNAs in CRC, miR-330-3p has the greatest probability to inhibit BMI1. Therefore, the experimental validation of miR-330-3p/BMI1 axis would be useful in identifying novel therapeutics and biomarkers in CRC. \u0000Keywords: Colorectal Cancer, miRNA, BMI1, Bioinformatics","PeriodicalId":36354,"journal":{"name":"Middle East Journal of Rehabilitation and Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47240874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}