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Comparison of access to stroke diagnostics, treatment, rehabilitation, and outcome between men and women 男性和女性卒中诊断、治疗、康复和预后的比较
Global Epidemiology Pub Date : 2025-04-29 DOI: 10.1016/j.gloepi.2025.100201
Josefine Grundtvig , Katrine Sværke , Mathilde Preskou , Louisa Marguerite Christensen , Thorsten Steiner , Hanne Christensen
{"title":"Comparison of access to stroke diagnostics, treatment, rehabilitation, and outcome between men and women","authors":"Josefine Grundtvig ,&nbsp;Katrine Sværke ,&nbsp;Mathilde Preskou ,&nbsp;Louisa Marguerite Christensen ,&nbsp;Thorsten Steiner ,&nbsp;Hanne Christensen","doi":"10.1016/j.gloepi.2025.100201","DOIUrl":"10.1016/j.gloepi.2025.100201","url":null,"abstract":"<div><h3>Background</h3><div>We aimed to compare access to diagnostics, treatment, rehabilitation, and outcome in women and men with stroke.</div></div><div><h3>Methods</h3><div>In this observational study we used routinely-collected, aggregate health data from all patients admitted with a stroke in the Capital Region and Region Zealand, Denmark from May 2016 until October 2022.</div></div><div><h3>Results</h3><div>Among 28,855 stroke patients (55 % men, 45 % women), women were older (53 % women vs. 47 % men with age &gt; 75 years). Overall, women had reduced access to: magnetic resonance imaging (MRI; 40 % vs. 43 %, CI 95 %: 1.06–1.16), computer tomography (CT)-angiography (25 % vs. 28 %, CI95%: 1.07–1.19), carotid ultrasound (48 % vs. 52 %, CI95%: 1.12–1.23), thrombolysis (16 % vs. 18 %, CI95%: 1.13–1.28), and neuropsychological assessment (9 % vs. 16 %, CI95%: 1.70–1.97). Home discharge rates were lower for women (45 % vs. 47 %, CI95%: 1.04–1.15), while in-hospital mortality was higher (8 % vs. 6 %, CI95%: 0.59–0.71). For patients &gt;75 years, women had less access to MRI (34 % vs. 35 %, CI95%: 1–1.16), carotid ultrasound (46 % vs. 51 %, CI95%: 1.13–1.30), thrombolysis (15 % vs. 16 %, CI95%: 1.02–1.24), and neuropsychological assessment (2 % vs. 4 %, CI95%: 1.60–2.42). Women's in-hospital mortality remained higher also in patients &gt;75 years (12 % vs. 8 %, CI95%: 0.62–0.79).</div></div><div><h3>Conclusions</h3><div>Women had reduced access to testing, treatment, and rehabilitation across all age groups and stroke types. This disparity was most notable in interventions not included in the national quality assessment program.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100201"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Chikungunya, Dengue, and West Nile arboviruses in Iran based on enzyme-linked immunosorbent assay (ELISA): A systematic review and meta-analysis 基于酶联免疫吸附试验(ELISA)的伊朗基孔肯雅、登革热和西尼罗河虫媒病毒流行情况:一项系统综述和荟萃分析
Global Epidemiology Pub Date : 2025-04-28 DOI: 10.1016/j.gloepi.2025.100202
Ebrahim Abbasi , Mohammad Djaefar Moemenbellah-Fard
{"title":"Prevalence of Chikungunya, Dengue, and West Nile arboviruses in Iran based on enzyme-linked immunosorbent assay (ELISA): A systematic review and meta-analysis","authors":"Ebrahim Abbasi ,&nbsp;Mohammad Djaefar Moemenbellah-Fard","doi":"10.1016/j.gloepi.2025.100202","DOIUrl":"10.1016/j.gloepi.2025.100202","url":null,"abstract":"<div><h3>Introduction</h3><div>Arboviruses, including Chikungunya (CHIKV), Dengue (DENV), and West Nile (WNV) viruses, are significant viral threats that affect numerous people globally each year. This report explores the prevalence of these viruses in Iran through a systematic review and meta-analysis.</div></div><div><h3>Methods</h3><div>The present survey was performed using a systematic review and meta-analysis method on the seroprevalence of WNV, CHIKV, and DENV using the ELISA test. Accordingly, by searching Web of Science, PubMed, Scopus, Cochrane Library, Science Direct, and Google Scholar scientific databases, all relevant published papers were sorted out and reviewed. Power ratification of data was conducted with a random effects model in meta-analysis, meta-regression, <em>I</em><sup><em>2</em></sup> index, and Egger test.</div></div><div><h3>Results</h3><div>This meta-analysis report embodies twelve published papers between 2000 and 2024. The seroprevalence of positive ELISA tests for WNV in Iran was estimated at 12.9 % (CI = 95 %: 7.4–18.4) and for CHIKV at 6.2 % (CI = 95 %: 0.6–11.8). Regarding DENV, only two studies were conducted, with a zero prevalence in one study and a seroprevalence of 5.6 % in another study.</div></div><div><h3>Conclusion</h3><div>According to these data, WNV, CHIKV, and DENV fevers have been detected in Iran using the ELISA test. Considering the seropositivity of WNV and CHIKV and their detection in several provinces, it can be assumed that these viruses are ubiquitous, while DENV fever remains sporadic in Iran.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resurgence in focus: Covid-19 dynamics and optimal control frameworks 重新聚焦:Covid-19动态和最优控制框架
Global Epidemiology Pub Date : 2025-04-22 DOI: 10.1016/j.gloepi.2025.100200
Evans O. Omorogie , Kolade M. Owolabi , Bola T. Olabode , Tunde T. Yusuf , Edson Pindza
{"title":"Resurgence in focus: Covid-19 dynamics and optimal control frameworks","authors":"Evans O. Omorogie ,&nbsp;Kolade M. Owolabi ,&nbsp;Bola T. Olabode ,&nbsp;Tunde T. Yusuf ,&nbsp;Edson Pindza","doi":"10.1016/j.gloepi.2025.100200","DOIUrl":"10.1016/j.gloepi.2025.100200","url":null,"abstract":"<div><div>The resurgence of Covid-19, accompanied by various variants of the virus, highlights the fact that Covid-19 is still present within the population. The study proposed a Covid-19 dynamical model for analyzing the effect of vaccination and the continuous use of non-medical interventions for addressing Covid-19 transmission dynamics. The Lyaponov function and Jacobian matrix techniques were used to analyze the stability of the model's equilibria. The model was transformed into a problem of optimal control with time-dependent variables, aimed at managing efforts to prevent the spread of Covid-19. Numerical assessments were deployed to assess the effect of vaccination and the continuous use of non-medical intervention strategies to mitigate the spread of Covid-19. The global sensitivity analysis of the model was used to detect the key parameters influencing the behavior of the model. In addition, numerical results showed a significant decrease in the basic reproduction rate <span><math><mfenced><msub><mi>ℛ</mi><mn>0</mn></msub></mfenced></math></span> when implementing <span><math><mi>σ</mi></math></span> and <span><math><mi>ξ</mi></math></span>, either separately or together. The optimal control results suggested that the control measures should be consistently enforced without any relaxation.</div><div>2010 Mathematics Subject Classification: 92D30, 93C95, 49 N90, 34H05, 37 N25.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100200"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive analysis of stroke epidemiology in Vietnam: Insights from GBD 1990–2019 and RES-Q 2017–2023 越南脑卒中流行病学综合分析:GBD 1990-2019和RES-Q 2017-2023的见解
Global Epidemiology Pub Date : 2025-04-10 DOI: 10.1016/j.gloepi.2025.100199
Minh Cong Tran , Lara Prisco , Phuong Minh Pham , Huy Quoc Phan , Mario Ganau , Nhat Pham , Linh Huyen Truong , Proochista Ariana , Phuong Viet Dao , Dung Tien Nguyen , Chi Van Nguyen , Hoa Thi Truong , Thang Huy Nguyen , Jeyaraj Pandian , Ton Duy Mai , Andrew Farmery
{"title":"Comprehensive analysis of stroke epidemiology in Vietnam: Insights from GBD 1990–2019 and RES-Q 2017–2023","authors":"Minh Cong Tran ,&nbsp;Lara Prisco ,&nbsp;Phuong Minh Pham ,&nbsp;Huy Quoc Phan ,&nbsp;Mario Ganau ,&nbsp;Nhat Pham ,&nbsp;Linh Huyen Truong ,&nbsp;Proochista Ariana ,&nbsp;Phuong Viet Dao ,&nbsp;Dung Tien Nguyen ,&nbsp;Chi Van Nguyen ,&nbsp;Hoa Thi Truong ,&nbsp;Thang Huy Nguyen ,&nbsp;Jeyaraj Pandian ,&nbsp;Ton Duy Mai ,&nbsp;Andrew Farmery","doi":"10.1016/j.gloepi.2025.100199","DOIUrl":"10.1016/j.gloepi.2025.100199","url":null,"abstract":"<div><h3>Background</h3><div>Stroke is a significant health burden in Vietnam, with substantial impacts on mortality, morbidity, and healthcare resources. An up-to-date report on stroke epidemiology and associated risk factors in Vietnam was missing.</div></div><div><h3>Method</h3><div>We analyzed the data published in the Global Burden of Disease (GBD) 2019, in combination with the first-time analysis of the Registry of Stroke Care Quality Improvement (RES-Q) initiative in Vietnam from 2017 to 2023.</div></div><div><h3>Findings</h3><div>Comparative analysis globally revealed that Vietnam had one of the highest stroke incidence and prevalence rates in Southeast Asia and ranked 4th in stroke mortality among 11 neighbouring countries. In the RES-Q dataset, 95,696 patients (77 %) were ischemic stroke, 23,203 (18 %) were intracerebral haemorrhage, and 2816 (2 %) were subarachnoid haemorrhage. In GBD 2019, stroke was the leading cause of death among cardiovascular diseases in Vietnam, accounting for 135,999 fatalities. The incidence of stroke was 222 (95 % UIs 206–242) per 100,000 population, with a prevalence of 1541 (1430-1679) per 100,000. Results align with the report from the RES-Q dataset in two megacities of Vietnam: Hanoi (incidence rate of 168.9, prevalence rate of 1182.2) and Ho Chi Minh City (incidence rate of 207.1, prevalence rate of 1221.8). Key risk factors for stroke mortality are high systolic blood pressure (79,000 deaths), unhealthy dietary (43,000 deaths), high fasting plasma glucose (35,000 deaths), and air pollution (33,000 deaths). Incidence is lower in rural Vietnam, but availability and quality of care are higher in megacities.</div></div><div><h3>Interpretation</h3><div>The results promote a further understanding of stroke and risk factors for the Vietnamese population and suggest prevention and treatment strategies for the Vietnamese government, including facility and capacity improvement and applications of advanced technologies.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100199"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating risk of acquiring SARS-COV2 infection in treatment-experienced PLWH: A case-control study 估计接受过治疗的PLWH感染SARS-COV2的风险:一项病例对照研究
Global Epidemiology Pub Date : 2025-03-22 DOI: 10.1016/j.gloepi.2025.100198
Pierluigi Francesco Salvo , Valentina Iannone , Francesca Lombardi , Arturo Ciccullo , Francesco Lamanna , Rosa Anna Passerotto , Gianmaria Baldin , Rebecca Jo Steiner , Andrea Carbone , Valentina Massaroni , Simona Di Giambenedetto , Alberto Borghetti
{"title":"Estimating risk of acquiring SARS-COV2 infection in treatment-experienced PLWH: A case-control study","authors":"Pierluigi Francesco Salvo ,&nbsp;Valentina Iannone ,&nbsp;Francesca Lombardi ,&nbsp;Arturo Ciccullo ,&nbsp;Francesco Lamanna ,&nbsp;Rosa Anna Passerotto ,&nbsp;Gianmaria Baldin ,&nbsp;Rebecca Jo Steiner ,&nbsp;Andrea Carbone ,&nbsp;Valentina Massaroni ,&nbsp;Simona Di Giambenedetto ,&nbsp;Alberto Borghetti","doi":"10.1016/j.gloepi.2025.100198","DOIUrl":"10.1016/j.gloepi.2025.100198","url":null,"abstract":"<div><h3>Background</h3><div>Risk factors for acquiring SARS-CoV-2 infection in people living with HIV (PLWH) and the true relationship between HIV and SARS CoV-2, are still not fully understood.</div></div><div><h3>Objectives</h3><div>The aim of this study was to identify the independent risk factors for SARS-CoV-2 acquisition in treatment experienced PLWH, shedding light on potential risk factors associated with SARS CoV-2 infection in PLWH undergoing treatment.</div></div><div><h3>Study design</h3><div>PLWH were recruited from the Infectious Diseases Outpatient Clinic of Fondazione Policlinico Universitario A.Gemelli IRCCS in Italy and randomly interviewed via a questionnaire during their follow-up visits to determine if they had experienced a SARS-CoV-2 infection between March 2020 and June 2022.</div><div>For each participant with reported history of SARS-CoV-2 (cases), two PLWH with no declared COVID-19 infection were selected (controls); PLWH had a similar potential exposure time to SARS-CoV-2. A total 220 PLWH were selected: 72 cases and 148 controls. None developed severe Covid-19 disease and only one participant required hospitalization.</div></div><div><h3>Results</h3><div>Overall, 220 PLWH were enrolled: 72 cases and 148 controls. Characteristics of cases and controls were similar, except for the ART regimen used and the last HIV-RNA concentration before the enrollment date. By an adjusted multivariable logistic regression, the estimated odds of SARS-CoV-2 infection was higher in more recent years (2022 versus 2020 aOR 20.74, 95 % CI 5.26–81.8) and in PLWH with last HIV-RNA &gt;50 cp/mL before enrollment date (versus &lt;50 aOR 4.56, 95 % CI 1.01–20.46). A reduced odds was correlated with &gt;3 vaccine doses (versus &lt;3 or not vaccinated aOR 0.08, 95 % CI 0.02–0.24).</div></div><div><h3>Conclusion</h3><div>In this cohort, the odds of SARS-CoV-2 acquisition increased over time, probably due to change in lock-down measures and in SARS-CoV-2 circulating variants.Detectable viral load was associated with increased risk of infection, highlighting the importance of HIV-RNA monitoring during pandemics.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100198"},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mpox: Characterization and clinical outcomes of patients in Colombian healthcare institutions Mpox:哥伦比亚卫生保健机构患者的特征和临床结果
Global Epidemiology Pub Date : 2025-03-14 DOI: 10.1016/j.gloepi.2025.100197
Carlos Arturo Álvarez-Moreno , Ludovic Reveiz , Claudia Aristizabal , Jesús Quevedo , María Lucia Mesa Rubio , Leonardo Arévalo-Mora , Julián Felipe Porras Villamil , Monica Padilla , Juan Carlos Alzate-Angel , Jamie Rylance , Kurbonov Firdavs , Ilich de la Hoz , Sandra Liliana Valderrama-Beltran , Santiago Arboleda , Otto Sussmann , Javier Andrade , Carolina Murillo Velásquez , Estefania García , Ximena Galindo , Daniela Martínez , Antoine Chaillon
{"title":"Mpox: Characterization and clinical outcomes of patients in Colombian healthcare institutions","authors":"Carlos Arturo Álvarez-Moreno ,&nbsp;Ludovic Reveiz ,&nbsp;Claudia Aristizabal ,&nbsp;Jesús Quevedo ,&nbsp;María Lucia Mesa Rubio ,&nbsp;Leonardo Arévalo-Mora ,&nbsp;Julián Felipe Porras Villamil ,&nbsp;Monica Padilla ,&nbsp;Juan Carlos Alzate-Angel ,&nbsp;Jamie Rylance ,&nbsp;Kurbonov Firdavs ,&nbsp;Ilich de la Hoz ,&nbsp;Sandra Liliana Valderrama-Beltran ,&nbsp;Santiago Arboleda ,&nbsp;Otto Sussmann ,&nbsp;Javier Andrade ,&nbsp;Carolina Murillo Velásquez ,&nbsp;Estefania García ,&nbsp;Ximena Galindo ,&nbsp;Daniela Martínez ,&nbsp;Antoine Chaillon","doi":"10.1016/j.gloepi.2025.100197","DOIUrl":"10.1016/j.gloepi.2025.100197","url":null,"abstract":"<div><h3>Introduction</h3><div>In 2022, the world experienced a monkeypox outbreak caused by the Clade IIb strain of the virus. While this outbreak had widespread effects, more information is needed on mpox's specific impact in Colombia, particularly regarding how it is managed, its burden, and its epidemiology. This research seeks to examine the medical context, clinical presentation, and health outcomes of individuals diagnosed with mpox infection, with a particular focus on those with HIV in Colombia.</div></div><div><h3>Methods</h3><div>This retrospective study was conducted in fourteen Health institutions in Colombia based on computerized clinical records from Jan 2022 to Dec 2023. Clinical and epidemiological characteristics were collected from diagnosis until discharge (or death). Participants in the study were diagnosed through molecular methods (PCR) and their clinical evolution was tracked through hospital and/or outpatient medical records. Registered variables were based on the mpox 2023 Case Report Form (2023 - CRF) proposed by the World Health Organization.</div></div><div><h3>Results</h3><div>One thousand four hundred thirteen (1413, 97.2 % male) individuals, including 2.6 % identified as healthcare workers, were included in this study. The majority (54 %, 764/1413 individuals) were persons living with HIV (PWH) and almost one-third of them (30.1 %, <em>n</em> = 284) of participants had concomitant sexually transmitted diseases and HIV, with syphilis being the most prevalent (20.4 %), followed by <em>Neisseria gonorrhoeae</em> (16.4 %). Complications were infrequent, with cellulitis being the most common, and no individuals received mpox-specific treatment or vaccination. Although all individuals had skin lesions distributed across various body regions, differences were noted in lesion distribution among women. Those living with HIV showed higher emergency department attendance and reported having known mpox contacts. While complications were rare, with cellulitis being the most common, women living with HIV showed a higher rate of emergency room visits and known mpox contacts. Although not statistically significant, gastrointestinal, musculoskeletal, psychological, respiratory, and STI symptoms, including syphilis and urethritis, were more common in the virologically non-suppressed HIV group. At the same time, proctitis was more prevalent in the suppressed group. No significant differences were found based on CD4 count, using 200 cells/mm<sup>3</sup> in PWH.</div></div><div><h3>Conclusion</h3><div>Over half of the participants were people living with HIV (PWH), with a significant presence of STIs like syphilis. While skin lesions and complications varied, no significant differences were linked to CD4 count or viral load suppression. Mpox symptomatology was not significantly associated with unsuppressed viral loads or low CD4 levels, highlighting the need for further research.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100197"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns and Associated Factors of Congenital Anomalies Among Neonates in 14 Yemeni Governorates 2021–2023: A Case: Control Study 也门14个省份2021-2023年新生儿先天性异常的模式和相关因素:一个病例:对照研究
Global Epidemiology Pub Date : 2025-03-14 DOI: 10.1016/j.gloepi.2025.100196
Hiam Al-Atnah , Anas Al-Qubati , Amir Addin Al-Hashedi , Muath Al-Saidy , Saleh Al-Shawish , Moamer M. Badi , Najeeb Al-Qubati , Yasser Ghaleb , Maha Al-Muntaser
{"title":"Patterns and Associated Factors of Congenital Anomalies Among Neonates in 14 Yemeni Governorates 2021–2023: A Case: Control Study","authors":"Hiam Al-Atnah ,&nbsp;Anas Al-Qubati ,&nbsp;Amir Addin Al-Hashedi ,&nbsp;Muath Al-Saidy ,&nbsp;Saleh Al-Shawish ,&nbsp;Moamer M. Badi ,&nbsp;Najeeb Al-Qubati ,&nbsp;Yasser Ghaleb ,&nbsp;Maha Al-Muntaser","doi":"10.1016/j.gloepi.2025.100196","DOIUrl":"10.1016/j.gloepi.2025.100196","url":null,"abstract":"<div><h3>Background</h3><div>Long-term disability and a reduced quality of life are often associated with congenital anomalies (CAs), which present as structural, functional, or metabolic defects. This study provides a comprehensive view of neonatal congenital anomalies in 14 Yemeni governorates, a significant but often overlooked public health concern. The current study aimed to determine the patterns and associated factors of congenital anomalies in 14 Yemeni governorates between 2021 and 2023.</div></div><div><h3>Methods</h3><div>An unmatched case-control 1:2 design was conducted using secondary data collected from various health facilities across 14 Yemeni governorates during 2021–2023. Sample size was calculated and data was analyzed using Epi Info version 7.2, with 612 neonates with documented diagnosis of congenital anomalies and 1224 healthy neonates. Binary and multiple logistic regression were used to identify factors associated with congenital anomalies, alongside the chi-square test.</div></div><div><h3>Results</h3><div>The majority of the congenital anomalies identified were located in Al Hudaydah (34 %), Ibb (17.2 %), and Sana'a (13.1 %). Most were isolated 518 (84.64 %), whereas 94 (15.36 %) were multiple. The predominant system was the nervous system (33.9 %), followed by the skeletal system (14.8 %) and orofacial anomalies (10.6 %). Furthermore, strong associations were found with positive consanguinity (OR = 28.82), low socioeconomic status (OR = 10.70), maternal age ≥ 35 years old (OR = 7.66), stress (OR = 4.95), acute diseases (OR = 3.56), gestational age &lt; 37 weeks (OR = 3.32), maternal age &lt; 20 years old (OR = 2.32), positive family history (OR = 1.74), low birth weight (OR = 1.27), grand-multiparity (OR = 0.71) and male sex (OR = 0.10).</div></div><div><h3>Interpretation</h3><div>This broad research identified significant patterns, maternal and neonatal associations, and protective variables for congenital anomalies. These results can help inform national interventions and policies for prevention and improving neonatal care.</div></div><div><h3>Funding</h3><div>This study was self-funded by the authors and did not receive any external funding or any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and characteristics of tobacco use among adults in Kazakhstan: A cross-sectional National Survey 哈萨克斯坦成年人烟草使用的流行率和特征:一项横断面全国调查
Global Epidemiology Pub Date : 2025-03-06 DOI: 10.1016/j.gloepi.2025.100194
Anel Ibrayeva , Marat Shoranov , Rassulbek Aipov , Adil Katarbayev , Shynar Tanabayeva , Ildar Fakhradiyev
{"title":"Prevalence and characteristics of tobacco use among adults in Kazakhstan: A cross-sectional National Survey","authors":"Anel Ibrayeva ,&nbsp;Marat Shoranov ,&nbsp;Rassulbek Aipov ,&nbsp;Adil Katarbayev ,&nbsp;Shynar Tanabayeva ,&nbsp;Ildar Fakhradiyev","doi":"10.1016/j.gloepi.2025.100194","DOIUrl":"10.1016/j.gloepi.2025.100194","url":null,"abstract":"<div><h3>Background</h3><div>Smoking remains a major public health concern worldwide, contributing significantly to morbidity and mortality. Despite the implementation of tobacco control measures, smoking prevalence in Kazakhstan remains high. This study aims to assess the prevalence, demographic characteristics, and regional variations in smoking habits among adults in Kazakhstan.</div></div><div><h3>Methods</h3><div>A cross-sectional national survey was conducted from October 2021 to May 2022, covering all 17 regions of Kazakhstan. A total of 6720 adults aged 18–69 years participated, selected using a weighted multistage cluster sampling method. Data were collected through structured interviews based on the WHO STEPwise approach. Smoking status, tobacco consumption patterns, and smoking cessation attempts were analyzed. The results were reported as means with 95 % confidence intervals (CI).</div></div><div><h3>Findings</h3><div>The overall smoking prevalence was 19.1 %. Smoking was significantly more common among men (30.3 %) than women (7.9 %). The highest smoking prevalence was observed in the 30–44 age group (44.2 %) and among private-sector employees (53.2 %). Regional differences were notable, with the lowest smoking prevalence in Atyrau (9.2 %) and the highest in Pavlodar (30.4 %). Among current smokers, 89.1 % smoked daily, with an average of 11.8 cigarettes per day (95 % CI: 11.4–12.2). Only 36.7 % of smokers who visited healthcare professionals in the past year received advice to quit. Additionally, 42.8 % attempted to quit smoking in the past 12 months. Passive smoking exposure was common, with 26.8 % of women and 22.3 % of men exposed at home, and 30.2 % of men and 14.4 % of women exposed at work. The prevalence of smokeless tobacco use was low (1 %).</div></div><div><h3>Interpretation</h3><div>Smoking remains prevalent among adults in Kazakhstan, with significant differences by gender, age, occupation, and region. The high prevalence of daily smoking and the low frequency of smoking cessation advice from healthcare professionals indicate the need for stronger tobacco control policies, targeted public health campaigns, and enhanced smoking cessation support programs. These findings provide a basis for future research and policy-making efforts aimed at reducing tobacco consumption and its associated health risks.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100194"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An overview of reviews of breastfeeding barriers and facilitators: Analyzing global research trends and hotspots 母乳喂养障碍和促进因素综述:分析全球研究趋势和热点
Global Epidemiology Pub Date : 2025-03-06 DOI: 10.1016/j.gloepi.2025.100192
Agustín Ramiro Miranda , Paula Eugenia Barral , Ana Veronica Scotta , Mariela Valentina Cortez , Elio Andrés Soria
{"title":"An overview of reviews of breastfeeding barriers and facilitators: Analyzing global research trends and hotspots","authors":"Agustín Ramiro Miranda ,&nbsp;Paula Eugenia Barral ,&nbsp;Ana Veronica Scotta ,&nbsp;Mariela Valentina Cortez ,&nbsp;Elio Andrés Soria","doi":"10.1016/j.gloepi.2025.100192","DOIUrl":"10.1016/j.gloepi.2025.100192","url":null,"abstract":"<div><div>Breastfeeding is the most cost-effective intervention for reducing infant morbidity and mortality, offering benefits for infants and mothers. Despite extensive promotion, global adherence remains below 50 %, resulting in significant clinical, economic, and environmental impacts. Thus, this overview of reviews aims to synthesize barriers and facilitators of breastfeeding, analyze research trends, and identify gaps to guide future research. A comprehensive literature search was conducted, including systematic reviews that examine these factors. The search covered seven electronic data repositories. The methodological quality was assessed using the Risk of Bias in Systematic Reviews tool. Bibliometric analysis focused on identifying top journals, authors, and countries, assessing their impact, and exploring trends over time. Findings were classified and analyzed thematically through line-by-line coding, theme description, and analytical formulation. A total of 123 reviews were included, mostly of high quality and published in top journals. Key trends comprised a growing focus on psychosocial and cultural factors, increased representation from low- and middle-income countries, and improved methodological rigor. However, geographical representation remains biased towards high-income countries, and some breastfeeding outcomes need further exploration. Thematic analysis revealed four categories: Therapeutic and care interventions; Support networks and education; Maternal-infant health issues; and Societal and environmental context. In conclusion, this overview of reviews identifies barriers and facilitators of breastfeeding and emphasizes the need for more inclusive research and tailored support. Addressing gaps in evidence for enhancing healthcare systems and policies can improve breastfeeding practices and outcomes worldwide.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100192"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reproductive health services utilization and associated factors among university youth students in Ethiopia: A mixed-methods study 埃塞俄比亚大学生生殖健康服务利用及其相关因素:一项混合方法研究
Global Epidemiology Pub Date : 2025-03-06 DOI: 10.1016/j.gloepi.2025.100195
Tsiyon Birhanu Wube , Solomon Gebremichael Asgedom , Dawit Gebregziabher Abrha , Lielt Gebreselassie Gebrekirstos
{"title":"Reproductive health services utilization and associated factors among university youth students in Ethiopia: A mixed-methods study","authors":"Tsiyon Birhanu Wube ,&nbsp;Solomon Gebremichael Asgedom ,&nbsp;Dawit Gebregziabher Abrha ,&nbsp;Lielt Gebreselassie Gebrekirstos","doi":"10.1016/j.gloepi.2025.100195","DOIUrl":"10.1016/j.gloepi.2025.100195","url":null,"abstract":"<div><h3>Background</h3><div>Reproductive health services utilization among youth university students is essential for their sexual and reproductive well-being. Despite growing awareness, students often face barriers—cultural, social, and economic—that limit their access to these services. Understanding service utilization patterns and associated factors is crucial for addressing unmet needs, such as limited access to family planning, maternal care, and sexual health services, as well as the lack of resources and awareness, which affect the quality of care and access to services. The study investigated the utilization of the services among youth university students, aiming to provide insights for targeted interventions and enhanced service delivery.</div></div><div><h3>Methods</h3><div>We conducted an institutional-based cross-sectional study with 768 youth university students, using a mixed-methods approach. Participants were selected via a multistage sampling technique. Data were collected through a self-administered questionnaire, supplemented by key informant interviews and in-depth interviews. Quantitative analysis was performed using SPSS version 25, and qualitative data were transcribed and analyzed narratively through content analysis. Logistic regression was employed to identify associations with service utilization.</div></div><div><h3>Results</h3><div>The study found that the prevalence of adequate reproductive health service utilization rate was 42.5 % (95 % CI: 38.81 % - 46.20 %), which is comparable to similar studies conducted in other low- and middle-income countries. Key factors included open discussions about reproductive health (AOR = 4.1, 95 % CI: 2.14–7.16), positive attitudes towards services (AOR = 6.03, 95 % CI: 3.72–9.75), and perceived HIV risk (AOR = 4.32, 95 % CI: 2.39–7.77).</div></div><div><h3>Conclusion</h3><div>Utilization of reproductive health services is relatively low, with only 42.5 % reporting usage. Key factors influencing utilization include open discussions, positive attitudes towards services, and perceived HIV risk. Addressing barriers through inclusive, youth-friendly interventions such as peer education programs could significantly improve outcomes.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"9 ","pages":"Article 100195"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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