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Barriers and facilitators to healthcare access for migrants in Morocco: A narrative review 摩洛哥移民获得医疗保健的障碍和促进因素:叙述性审查
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-01-15 DOI: 10.1016/j.gloepi.2026.100249
Amaghdour Chaimaa , Farhan Houssein Ali , Belouali Radouane , Hassouni Kenza
{"title":"Barriers and facilitators to healthcare access for migrants in Morocco: A narrative review","authors":"Amaghdour Chaimaa ,&nbsp;Farhan Houssein Ali ,&nbsp;Belouali Radouane ,&nbsp;Hassouni Kenza","doi":"10.1016/j.gloepi.2026.100249","DOIUrl":"10.1016/j.gloepi.2026.100249","url":null,"abstract":"<div><h3>Background</h3><div>International migration has increased significantly in recent decades, creating major challenges for health systems, particularly in transit and destination countries such as Morocco. Migrants, often living in precarious socio-economic conditions, face multiple obstacles to healthcare access, which heightens their vulnerability. This narrative review aims to identify the main barriers and facilitators to healthcare access for migrants in Morocco, using Levesque's conceptual framework.</div></div><div><h3>Methods</h3><div>A literature search was conducted in PubMed, Web of Science, Scopus and Google Scholar, as well as in institutional sources (WHO, IOM, UNHCR, HCP). Relevant publications published between 2013 and 2025 in French or English were critically reviewed. The analysis was structured according to the five dimensions of Levesque's framework: accessibility, acceptability, availability, affordability and appropriateness.</div></div><div><h3>Results</h3><div>Twenty-two publications were included. Findings reveal that migrants in Morocco face economic, geographical, linguistic, sociocultural, administrative and structural barriers. Financial constraints, lack of health coverage, and regional disparities are among the most significant obstacles. However, several facilitators were also identified, including NGO initiatives, community-based support, and inclusive public policies.</div></div><div><h3>Conclusion</h3><div>Migrant access to healthcare in Morocco remains shaped by complex and multidimensional challenges. Despite notable progress, greater coordination, sustainability, and cultural sensitivity are required to ensure equitable and universal access to healthcare for all migrants, regardless of legal or economic status.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100249"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety profile following mRNA-1273 COVID-19 primary vaccination in healthy adults in Indonesia 印度尼西亚健康成人接种mRNA-1273 COVID-19初级疫苗后的安全性概况
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-05-30 DOI: 10.1016/j.gloepi.2026.100269
Bernie Endyarni Medise , Nastiti Kaswandani , Nina Dwi Putri , Elcha Leonard , Putra Fajar Angkasa , Ade Putra , Rini Muliasari , Viska Indriani , Prima Yosephine , Julitasari Sundoro , Hindra Irawan Satari , Sri Rezeki Hadinegoro
{"title":"Safety profile following mRNA-1273 COVID-19 primary vaccination in healthy adults in Indonesia","authors":"Bernie Endyarni Medise ,&nbsp;Nastiti Kaswandani ,&nbsp;Nina Dwi Putri ,&nbsp;Elcha Leonard ,&nbsp;Putra Fajar Angkasa ,&nbsp;Ade Putra ,&nbsp;Rini Muliasari ,&nbsp;Viska Indriani ,&nbsp;Prima Yosephine ,&nbsp;Julitasari Sundoro ,&nbsp;Hindra Irawan Satari ,&nbsp;Sri Rezeki Hadinegoro","doi":"10.1016/j.gloepi.2026.100269","DOIUrl":"10.1016/j.gloepi.2026.100269","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the safety and benefit-risk profile of mRNA-1273 following the vaccine's authorization and the administration of over one million doses in Indonesia.</div></div><div><h3>Design</h3><div>A retrospective analytical study was conducted to assess adverse events following immunization (AEFI) within 28 days after the latest dose of primary vaccine of mRNA-1273 COVID-19 vaccine. Data collection was conducted on November 3rd - December 31st, 2022 in 18 public health centers and one hospital from five regions in Jakarta, Indonesia. All of the participants' candidates will be contacted by trained interviewers via telephone to answer the questionnaire.</div></div><div><h3>Results</h3><div>A total of 1284 subjects (response rate = 31.05%) were enrolled and interviewed, with 13 drop out subjects. The most common solicited local reactions were local pain, erythema and swelling, meanwhile for systemic systemic reaction was fever. Most solicited and systemic local reactions showed an increase in reported events on days 1–3 after vaccination and rapidly decreasing afterwards. After dose 2 of mRNA-1273 COVID-19 vaccine, local pain, was reported more frequently in females and younger age. There were four serious adverse events (SAE) reported in this study which classified as coincidence.</div></div><div><h3>Conclusion</h3><div>mRNA-1273 COVID-19 vaccination in Indonesia is safe.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100269"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148167661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AlzStack: Forecasting early-onset Alzheimer's with an explainable AI system using multiple data balancing techniques AlzStack:使用多种数据平衡技术,通过可解释的人工智能系统预测早发性阿尔茨海默病
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2025-12-07 DOI: 10.1016/j.gloepi.2025.100235
Venkata Aditi Modali , Manohar Pavanya , R. Vijaya Arjunan , D. Cenitta , Niranjana Sampathila , Radhika Kamath , Krishnaraj Chadaga
{"title":"AlzStack: Forecasting early-onset Alzheimer's with an explainable AI system using multiple data balancing techniques","authors":"Venkata Aditi Modali ,&nbsp;Manohar Pavanya ,&nbsp;R. Vijaya Arjunan ,&nbsp;D. Cenitta ,&nbsp;Niranjana Sampathila ,&nbsp;Radhika Kamath ,&nbsp;Krishnaraj Chadaga","doi":"10.1016/j.gloepi.2025.100235","DOIUrl":"10.1016/j.gloepi.2025.100235","url":null,"abstract":"<div><div>Alzheimer's disease (AD) is a degenerative neurological disease that progresses over time, making early detection crucial for effective intervention and better patient prognosis. Traditional diagnostic methods such as cognitive assessments, neuroimaging, and biomarker analysis can be time-consuming, costly, and inconsistent. We introduce AlzStack, a soft voting ensemble model to classify AD from a richly detailed dataset containing 2149 patients across demographic, medical, lifestyle, and cognitive variables. To resolve class imbalance, we implemented a pipeline 5-fold cross-validation, randomized search for hyper parameter tuning and advanced resampling methods such as SMOTE (Synthetic Minority Oversampling Technique), ADASYN, BorderlineSMOTE, and SVMSMOTE. Soft Vote Classifier surpassed both stacking ensembles and hard voting with an AUC value of 94.27 %, accuracy of 93.26 %, precision of 89.17 %, a recall of 92.11 %, and F1-score value of 90.61 %.A secondary experiment with only resampling methods applied to data to all base models served as a baseline for comparison confirming the superior performance of cross-validation AlzStack configuration. To improve interpretability, we utilized a wide range of Explainable Artificial Intelligence (XAI methods) and these approaches yielded global and local explanations about model behavior, emphasizing key features like MMSE scores, functional measures, and behavioral markers. Combining robust predictive performance with explainable decision-making makes AlzStack is a healthcare decision-support algorithm for the early detection of AD.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100235"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review of the tuberculosis burden in prisons: Regional patterns and gaps in Latin America and the Caribbean 监狱结核病负担的系统审查:拉丁美洲和加勒比的区域模式和差距
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-01-07 DOI: 10.1016/j.gloepi.2026.100244
Ricardo Perea-Jacobo , Jose Luis Soto-Ledesma , Rafael Laniado-Laborín , Dora-Luz Flores , Rogelio Zapata-Garibay , J. Eduardo González-Fagoaga , Luis Alberto García-Sánchez , Javier Robles-Flores , Liliana Guadalupe Villa-Aviles , Raquel Muñiz-Salazar
{"title":"Systematic review of the tuberculosis burden in prisons: Regional patterns and gaps in Latin America and the Caribbean","authors":"Ricardo Perea-Jacobo ,&nbsp;Jose Luis Soto-Ledesma ,&nbsp;Rafael Laniado-Laborín ,&nbsp;Dora-Luz Flores ,&nbsp;Rogelio Zapata-Garibay ,&nbsp;J. Eduardo González-Fagoaga ,&nbsp;Luis Alberto García-Sánchez ,&nbsp;Javier Robles-Flores ,&nbsp;Liliana Guadalupe Villa-Aviles ,&nbsp;Raquel Muñiz-Salazar","doi":"10.1016/j.gloepi.2026.100244","DOIUrl":"10.1016/j.gloepi.2026.100244","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically review and synthesize the available literature on the prevalence and incidence of tuberculosis in incarcerated populations in Latin America and the Caribbean, identifying regional patterns, data gaps, and key challenges and providing recommendations for strengthening TB control strategies within prison settings.</div></div><div><h3>Methods</h3><div>A systematic review was conducted across databases and reports using the following search terms: “tuberculosis”, “prisons”, “prisoners”, “Latin America”, “Caribbean”, “inmates”, and “social readaptation center”. The review focused on prevalence rates, country-specific studies, total prison population studied by country, diagnostic methods used, and the frequency of TB reporting.</div></div><div><h3>Results</h3><div>A total of 45 studies met the inclusion criteria, with most conducted in Brazil (60%), Colombia (13%), and Paraguay (9%). TB prevalence and incidence in prisons were found to be up to ten times higher than in the general population, with substantial variation in study design, diagnostic tools, and reporting standards. Structural risk factors such as overcrowding, HIV coinfection, and limited access to molecular diagnostics were frequently reported. Notably, no studies were found from Caribbean countries, and only one study was identified in Mexico, revealing significant regional data gaps.</div></div><div><h3>Conclusion</h3><div>TB in Latin American prisons represents a serious but underreported public health crisis. The combination of elevated incidence, limited diagnostics, and fragmented surveillance highlights the urgent need for standardized, prison-specific TB control strategies and expanded research in underrepresented regions.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpretation of the IARC quantitative bias analysis of talc and ovarian cancer 国际癌症研究机构对滑石粉与卵巢癌定量偏倚分析的解释
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-01-21 DOI: 10.1016/j.gloepi.2026.100251
Julie E. Goodman, Denali N. Boon
{"title":"Interpretation of the IARC quantitative bias analysis of talc and ovarian cancer","authors":"Julie E. Goodman,&nbsp;Denali N. Boon","doi":"10.1016/j.gloepi.2026.100251","DOIUrl":"10.1016/j.gloepi.2026.100251","url":null,"abstract":"<div><div>The International Agency for Research on Cancer (IARC) conducted a quantitative bias analysis (QBA) of talc use and ovarian cancer in Monograph 136. While the inclusion of a QBA was an important improvement compared to prior monographs, it was based on “best guesses” of sensitivity and specificity, rather than available data on talc recall. IARC incorporated some uncertainty in its analysis, but did not consider uncertainty around each sensitivity and specificity value. IARC concluded that a positive association between talc and ovarian cancer was credible but, even setting aside methodological issues, the QBA clearly showed that cohort study results were very similar before and after adjustment with various assumptions about sensitivity and specificity, and that case-control studies results were greatly attenuated. Thus, IARC's conclusions are inconsistent with the analyses presented in the Monograph, which clearly demonstrate that exposure misclassification could fully explain associations in case-control studies, and that epidemiology evidence does not support an association between talc and ovarian cancer. We propose that future IARC QBAs rely on empirical data rather than expert guesses (when possible), are fully transparent, consider all relevant information (including dose-response data), and use probabilistic and Bayesian analyses to address uncertainties.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100251"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of alcohol use and alcohol use disorders among the population of Buea, south west region, Cameroon: A survey study 喀麦隆西南地区Buea人口中酒精使用和酒精使用障碍的流行病学:一项调查研究
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2025-12-03 DOI: 10.1016/j.gloepi.2025.100236
Nadège Emégam Kouémou, Ven-Laura Atem Yega, Franklin Mbeboh Savo, Ndzweng Linda Tamanji
{"title":"Epidemiology of alcohol use and alcohol use disorders among the population of Buea, south west region, Cameroon: A survey study","authors":"Nadège Emégam Kouémou,&nbsp;Ven-Laura Atem Yega,&nbsp;Franklin Mbeboh Savo,&nbsp;Ndzweng Linda Tamanji","doi":"10.1016/j.gloepi.2025.100236","DOIUrl":"10.1016/j.gloepi.2025.100236","url":null,"abstract":"<div><h3>Background</h3><div>Alcohol consumption worldwide is associated with a range of health and societal problems. Epidemiology data are valuable tools for predicting the outcome of a given behaviour on the general population's health. This study aimed to evaluate the patterns of alcohol consumption among Buea inhabitants.</div></div><div><h3>Material and methods</h3><div>This cross-sectional study involves 422 participants (244 men and 178 women) aged 15 years and above who have been residents of the Buea municipality for more than a year. This study was conducted from March to May 2019 using a semi-structured questionnaire. The questionnaire included socio-demographic information and the 10 items of the Alcohol Use Disorder Identification Test (AUDIT).</div></div><div><h3>Results</h3><div>The results obtained showed that many of the alcohol misusers were men. 34.6 % of the participants indicated drinking above the recommended levels. 93.8 % of the respondents admitted to consuming alcohol in the company of others, mostly in bars. Beer was the leading alcoholic beverage consumed in Buea. Alcohol intake for pleasure and to relieve stress were among the leading causes of alcohol drinking in the study population. The vast majority of participants reported misbehavior after alcohol intake. The number of women with AUDIT C score greater than 5 was also significant. Aggressivity, memory loss, and falls after drinking were also recorded in the study population.</div></div><div><h3>Conclusion</h3><div>The alcohol consumption patterns in Buea are associated with many behavioral misconducts. Therefore, there is a need for community education to curve the incidence of neurological diseases and alcohol addiction behaviour in the Buea municipality.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100236"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of completing eight or more antenatal care contacts on adverse pregnancy outcomes in a district hospital in Ghana: A propensity score–matched and doubly robust analysis 在加纳的一家地区医院,完成八次或更多的产前护理接触对不良妊娠结局的影响:倾向评分匹配和双重稳健分析
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-02-20 DOI: 10.1016/j.gloepi.2026.100253
Frederick Osei Owusu , Emmanuel Konadu , Helena Addai-Manu , Julius Kwabena Karikari , Esther Serwah Agbedinu , Nuheila Ibrahim , Lydia Asenso , Mercy Addae , Joseph Osarfo , Bernice Enyonam Akpaloo , Mawuse Kanfra , Douglas Aninng Opoku
{"title":"Effect of completing eight or more antenatal care contacts on adverse pregnancy outcomes in a district hospital in Ghana: A propensity score–matched and doubly robust analysis","authors":"Frederick Osei Owusu ,&nbsp;Emmanuel Konadu ,&nbsp;Helena Addai-Manu ,&nbsp;Julius Kwabena Karikari ,&nbsp;Esther Serwah Agbedinu ,&nbsp;Nuheila Ibrahim ,&nbsp;Lydia Asenso ,&nbsp;Mercy Addae ,&nbsp;Joseph Osarfo ,&nbsp;Bernice Enyonam Akpaloo ,&nbsp;Mawuse Kanfra ,&nbsp;Douglas Aninng Opoku","doi":"10.1016/j.gloepi.2026.100253","DOIUrl":"10.1016/j.gloepi.2026.100253","url":null,"abstract":"<div><h3>Introduction</h3><div>Evidence from low- and middle-income countries (LMICs), especially using robust causal inference techniques to estimate the association between ≥8 antenatal care (ANC) contacts and adverse pregnancy outcomes, remains limited. This study examines the association between completing eight or more ANC contacts and adverse pregnancy outcomes, specifically low birth weight (LBW) and preterm birth (PTB).</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted using retrospective delivery data at Juaben Government Hospital, Ghana. LBW and PTB were compared between women who made ≥8 ANC contacts and those who did not. Propensity score matching (1:1), inverse probability of treatment weighting, and doubly robust estimates were employed to address confounding and estimate the association between completing ≥8 ANC contacts and LBW and PTB.</div></div><div><h3>Results</h3><div>At baseline, the sample included 2156 women, of whom over half (51.3%) had ≥8 ANC contacts before delivery. After matching, women in both groups had similar characteristics. After matching on covariates, women with ≥8 ANC contacts had approximately 31.0% (ATT: 0.69; 95%CI: 0.53–0.90) and 54.0% (ATT: 0.46; 95%CI: 0.37–0.57) lower risks of delivering a LBW infant and a PTB, respectively. Inverse probability of treatment weighting and doubly robust estimates yielded comparable estimates for both outcomes. In a secondary analysis of ≥4 ANC contacts, the magnitude of the association was weaker than that observed in the ≥8 ANC model.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that completing ≥8 ANC contacts was consistently associated with lower odds of LBW and PTB among this cohort of pregnant women. This finding adds to the limited empirical evidence from LMICs on the implementation of the WHO eight-contact ANC model, suggesting that higher ANC contacts in a similar resource-constrained setting may be associated with improved maternal and infant outcomes.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100253"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147384714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are arms-based methods required to test the stable unit treatment value assumption (SUTVA) among Cochrane reviews of contagious infection prevention interventions? 在Cochrane综述传染性感染预防干预措施中,是否需要基于武器的方法来检验稳定单位治疗价值假设(SUTVA) ?
Global Epidemiology Pub Date : 2026-06-01 DOI: 10.1016/j.gloepi.2026.100270
James C. Hurley
{"title":"Are arms-based methods required to test the stable unit treatment value assumption (SUTVA) among Cochrane reviews of contagious infection prevention interventions?","authors":"James C. Hurley","doi":"10.1016/j.gloepi.2026.100270","DOIUrl":"10.1016/j.gloepi.2026.100270","url":null,"abstract":"<div><div>Herd (spillover) effects of infection prevention interventions are of increasing interest and are usually presumed beneficial. Their presence invalidates the Stable Unit Treatment Value Assumption (SUTVA) but testing for them is not simple. Moreover, in deriving causal inference from randomized concurrent controlled trials (RCCT) SUTVA, whilst difficult to verify, must still be considered.</div><div>The effects of various interventions for preventing intensive care unit (ICU) acquired infections in high quality RCCTs were summarized in thirteen Cochrane reviews. Topical antibiotic prophylaxis or Selective digestive decontamination (TAP/SDD) appears the most effective intervention towards preventing pneumonia and mortality but what of SUTVA? Originally, TAP/SDD was presumed to mediate both direct and spillover (herd) effects with both presumed beneficial but four studies to estimate the TAP/SDD spillover effects were underpowered.</div><div>TAP/SDD is mediated through decolonization which, unlike vaccination interventions, rebounds on TAP/SDD cessation. Are TAP/SDD spillover effects harmful? A trial to demonstrate that TAP/SDD herd effects are safe, being logistically complex and ethically fraught, would be infeasible. This commentary explores whether the 13 Cochrane reviews might present a natural experiment with which to evaluate the spillover (herd) effects of TAP/SDD to establish its population safety. Failure to consider SUTVA within Cochrane and similar systematic reviews of prevention interventions for contagious infections represents a major threat as any apparent summary effect size might have conflated spillover and direct effects. Summary effects derived from RCCTs with harmful spillover effects would cause profoundly misleading inferences.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100270"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148167567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Undetected circulation of monkeypox virus in Portugal: Evidence for a 50-day gap before first detection 葡萄牙未被发现的猴痘病毒传播:首次发现前50天间隔的证据
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2025-12-15 DOI: 10.1016/j.gloepi.2025.100238
Rita Cordeiro , Fernando da Conceição Batista , Ana Pelerito , Isabel Lopes de Carvalho , Sílvia Lopo , Raquel Neves , Raquel Rocha , Paula Palminha , Maria José Borrego , Maria Sofia Núncio , João Paulo Gomes
{"title":"Undetected circulation of monkeypox virus in Portugal: Evidence for a 50-day gap before first detection","authors":"Rita Cordeiro ,&nbsp;Fernando da Conceição Batista ,&nbsp;Ana Pelerito ,&nbsp;Isabel Lopes de Carvalho ,&nbsp;Sílvia Lopo ,&nbsp;Raquel Neves ,&nbsp;Raquel Rocha ,&nbsp;Paula Palminha ,&nbsp;Maria José Borrego ,&nbsp;Maria Sofia Núncio ,&nbsp;João Paulo Gomes","doi":"10.1016/j.gloepi.2025.100238","DOIUrl":"10.1016/j.gloepi.2025.100238","url":null,"abstract":"<div><div>As mpox continues to spread globally, proactive monitoring and preparedness are crucial to minimize impact and enhance response strategies. Using a mathematical model combining a negative binomial distribution with Richards' logistic curve, we reconstructed the hidden phase of mpox transmission in Portugal, offering insights into the timing and dynamics of the initial outbreak. The analysis of 950 PCR-positive and 986 negative cases suggested that symptom onset occurred between March 24 and April 2, 2022, with March 27 identified as the most probable date. This study delineates the likely period of silent circulation of MPXV in Portugal, providing a clearer understanding of early outbreak dynamics and surveillance performance. Possible imperfections in early diagnostic testing and limited awareness of mpox may have contributed to delayed recognition of the outbreak. By demonstrating how retrospective mathematical modelling can estimate undetected transmission periods, our findings highlight the value of such approaches in epidemic reconstruction and underscore the importance of strengthening early surveillance systems to detect undiagnosed transmission of mpox in non-endemic countries.</div></div>","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Estimation of the global number of nicotine vapers in 2025” [Global Epidemiology 11 (2026) 100257] “估计2025年全球吸尼古丁电子烟人数”的勘误表[全球流行病学11 (2026)100257]
Global Epidemiology Pub Date : 2026-06-01 Epub Date: 2026-05-11 DOI: 10.1016/j.gloepi.2026.100263
Tomasz Jerzyński , Giorgi Mzhavanadze , Gerry V. Stimson
{"title":"Corrigendum to “Estimation of the global number of nicotine vapers in 2025” [Global Epidemiology 11 (2026) 100257]","authors":"Tomasz Jerzyński ,&nbsp;Giorgi Mzhavanadze ,&nbsp;Gerry V. Stimson","doi":"10.1016/j.gloepi.2026.100263","DOIUrl":"10.1016/j.gloepi.2026.100263","url":null,"abstract":"","PeriodicalId":36311,"journal":{"name":"Global Epidemiology","volume":"11 ","pages":"Article 100263"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148230805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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