BMJ Nutrition, Prevention and Health最新文献

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Preventable causes of cancer in Texas by race/ethnicity: insufficient physical activity. 德克萨斯州按种族/民族划分的可预防癌症原因:缺乏体育活动。
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-28 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000087
Franciska J Gudenkauf, Aaron P Thrift
{"title":"Preventable causes of cancer in Texas by race/ethnicity: insufficient physical activity.","authors":"Franciska J Gudenkauf, Aaron P Thrift","doi":"10.1136/bmjnph-2020-000087","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000087","url":null,"abstract":"Background According to the 2018 Third Expert Report from the World Cancer Research Fund/American Institute for Cancer Research, there is strong evidence that physical activity of all types and intensities protects against colon, endometrial and breast cancers. We aimed to estimate the percentage and number of incident cancer cases diagnosed in Texas in 2015 that were attributable to insufficient physical activity, and we examined for differences across racial/ethnic subgroups to reveal important causes of and potential avenues for reductions to cancer health disparities. Methods We calculated population attributable fractions for cancers attributable to insufficient physical activity using prevalence data from the Texas Behavioral Risk Factor Surveillance System and relative risk estimates associated with insufficient physical activity from prior studies. Cancer incidence data were gathered from the Texas Cancer Registry. Results Overall, approximately 2.0% of all new cancers or 2094 excess cancer cases diagnosed in 2015 in Texans aged ≥25 years were attributable to insufficient physical activity, with more cancers in women (3.2%) than in men (0.8%). Of all cancer sites, the highest population attributable fraction for insufficient physical activity was observed for endometrial cancers (21.7% compared with 12.7% for colon cancers, 10.9% for premenopausal breast cancers and 2.0% for postmenopausal breast cancers). Hispanics (2.6%) and non-Hispanic blacks (2.5%) had higher proportions of cancers attributable to insufficient physical activity than non-Hispanic whites (1.8%). Conclusions Public health programmes should stress physical activity as a means of cancer prevention, especially among minority groups, who may have disproportionately higher percentages of cancers attributable to insufficient physical activity.","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"172-179"},"PeriodicalIF":0.0,"publicationDate":"2020-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000087","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contrasting prenatal nutrition and environmental exposures in association with birth weight and cognitive function in children at 7 years. 对比产前营养和环境暴露与7岁儿童出生体重和认知功能的关系。
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-26 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000099
Chris Gennings, Alicja Wolk, Niclas Hakansson, Christian Lindh, Carl-Gustaf Bornehag
{"title":"Contrasting prenatal nutrition and environmental exposures in association with birth weight and cognitive function in children at 7 years.","authors":"Chris Gennings,&nbsp;Alicja Wolk,&nbsp;Niclas Hakansson,&nbsp;Christian Lindh,&nbsp;Carl-Gustaf Bornehag","doi":"10.1136/bmjnph-2020-000099","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000099","url":null,"abstract":"<p><strong>Background: </strong>Good nutrition is essential for individual health, a notion that is particularly true during pregnancy. We have used a nutrition index that measures the adequacy of one's diet relative to the unique nutritional needs of individuals due to, for example, their activity level, dietary restrictions, lifestyle and body size. The use of this personalised metric of dietary nutritiousness in the analysis of prenatal environmental exposures and developmental outcomes permits testing for potential mitigating effects of good nutrition. We also provide an analysis strategy for investigating the balance in beneficial food sources which are also the source of environmental toxicants.</p><p><strong>Methods: </strong>A holistic measure of nutrition, <i>My Nutrition Index</i> (MNI), measures the nutrient quality (ie, 'nutritiousness') of a specified daily diet. MNI is calculated based on quantification of dozens of macronutrients and micronutrients that are specific to an individual's nutritional needs by incorporating dietary restrictions, subject characteristics, activity level and health behaviours. The Swedish Environmental, Longitudinal, Mother and child, Asthma and allergy Study is a Swedish pregnancy cohort, with prenatal endocrine disrupting chemicals (EDCs) exposure and dietary data available. This makes it possible to test for the potential mitigating effects of good nutrition on health and development effects in offspring from EDCs.</p><p><strong>Results: </strong>Using prenatal Food Frequency Questionnaire data to construct an individual's MNI, the index was significantly and positively associated with important metabolic outcome (as measured by birth weight) and cognitive function at age 7 years (as measured by WISC IQ) in children when adjusted for covariates and prenatal concentrations of an EDC. In a stratified analysis of 'low' and 'high' fish consumption, a potential source of perfluoro-octanesulfonic acid (PFOS), the association between PFOS and birth weight was diminished in the high consumption group compared with the low consumption group.</p><p><strong>Conclusions: </strong>Thus, MNI is evidently a metric of the general nutritiousness of daily diets and is useful in environmental health studies in representing the impact of good nutrition, even during pregnancy.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"162-171"},"PeriodicalIF":0.0,"publicationDate":"2020-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Relationship between maternal body composition during pregnancy and infant's birth weight in Nairobi informal settlements, Kenya. 肯尼亚内罗毕非正式住区孕妇孕期身体成分与婴儿出生体重的关系
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-23 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2019-000060
Milkah Njeri Wanjohi, Irene Ogada, Frederick Murunga Wekesah, Christopher Khayeka-Wandabwa, Elizabeth W Kimani-Murage
{"title":"Relationship between maternal body composition during pregnancy and infant's birth weight in Nairobi informal settlements, Kenya.","authors":"Milkah Njeri Wanjohi,&nbsp;Irene Ogada,&nbsp;Frederick Murunga Wekesah,&nbsp;Christopher Khayeka-Wandabwa,&nbsp;Elizabeth W Kimani-Murage","doi":"10.1136/bmjnph-2019-000060","DOIUrl":"https://doi.org/10.1136/bmjnph-2019-000060","url":null,"abstract":"<p><strong>Background: </strong>Maternal nutrition depletion during pregnancy compromises fetal programming, and is a cause of adverse birth outcomes. Maternal body composition measurement using direct body composition assessment methods such as the deuterium dilution technique provides better prediction of birth outcomes as compared with commonly used techniques like anthropometry. This study assessed body composition of pregnant mothers in urban informal settlements in Nairobi, Kenya, and established the relationship between maternal body composition and infant birth weight.</p><p><strong>Methods: </strong>Deuterium dilution technique was used to determine body composition, including total body water (TBW), fat-free mass (FFM) and fat mass (FM), among 129 pregnant women who were enrolled into the study in their first or second trimester. Descriptive statistics and regression analysis were applied using Stata V.13.</p><p><strong>Results: </strong>The mean TBW, FFM and FM were 33.3 L (±4.7), 45.7 kg (±6.5) and 17.01 kg (±7.4), respectively. Both TBW and FFM were significantly related to maternal age and gestation/pregnancy stage during body composition assessment while FM was significantly associated with gestation stage during body composition assessment. TBW and FFM were significantly lower in younger mothers (<20 years) compared with older mothers (≥20 years). The mean birth weight was 3.3 kg±0.42 kg. There was a positive association between infant birth weight and maternal TBW (p=0.031) and FFM (p=0.027), but not FM (p=0.88).</p><p><strong>Conclusion: </strong>Non-fat components of the body (TBW and FFM) have a positive association with birth weight. Therefore, interventions to improve optimal maternal feeding practices, to enhance optimal gains in FFM and TBW during pregnancy are recommended, especially among young mothers.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"151-161"},"PeriodicalIF":0.0,"publicationDate":"2020-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2019-000060","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Empowering local communities to make lifestyle changes: is the Health Mela a potential solution? 增强当地社区改变生活方式的能力:“健康梅拉”是一个潜在的解决方案吗?
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-21 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000067
Joseph Watson, Rajbhandari Satyan, Romesh Gupta, Martin Myers, Robert Campbell, Elizabeth Macphie
{"title":"Empowering local communities to make lifestyle changes: is the Health Mela a potential solution?","authors":"Joseph Watson,&nbsp;Rajbhandari Satyan,&nbsp;Romesh Gupta,&nbsp;Martin Myers,&nbsp;Robert Campbell,&nbsp;Elizabeth Macphie","doi":"10.1136/bmjnph-2020-000067","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000067","url":null,"abstract":"<p><strong>Background: </strong>Health Melas are community-led public health events held in the North West of England that provide health information and free health checks. This descriptive observational study evaluates whether Health Melas are able to identify undiagnosed cardiovascular disease (CVD) risk factors in hard-to-reach communities and encourage individuals to make lifestyle changes.</p><p><strong>Methods: </strong>Attendees ≥18 years at three separate Health Melas in 2016-2017 were invited to participate in screening and counselling for CVD risk factors as part of a Health MOT. Information was collected about demographics, CVD risk factors, blood pressure, total cholesterol, blood sugar and attendees' feedback. QRISK2 scoring system was used to estimate CVD risk.</p><p><strong>Results: </strong>375 attendees completed a questionnaire. The highest proportion (36.9%) of attendees were from areas of the lowest Index of Health Deprivation and Disability quintile; 38.8% were of South Asian ethnicity. Of the attendees who were eligible for a free National Health Service Health Check, 9.1% had received one. Overall, 57.5% of all attendees had a QRISK2 score ≥10% (of whom 56.9% were not on statins), 92.2% of attendees believed the Health Mela will help them to make lifestyle changes, 98.2% said they had improved their understanding of their health, and 99.6% thought the Health Mela was useful. 73.6% of those who had received a previous Health MOT reported making lifestyle changes. There was a positive correlation between South Asian ethnicity and QRISK2 score.</p><p><strong>Conclusion: </strong>This study suggests the Health Melas successfully involve South Asian populations and people from a lower Index of Health Deprivation and Disability. Attendees felt the events were useful, improved understanding of their health needs and encouraged them to make lifestyle changes. High rates of modifiable CVD risk factors were newly identified and a high proportion of attendees were found to be at intermediate to high risk of CVD.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"143-150"},"PeriodicalIF":0.0,"publicationDate":"2020-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000067","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Building on what we know: moving beyond effectiveness to consider how to implement, sustain and spread successful health interventions. 以我们所知为基础:超越有效性,考虑如何实施、维持和传播成功的卫生干预措施。
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-12 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000115
Celia Laur, Lauren Ball, Heather Keller, Noah Ivers
{"title":"Building on what we know: moving beyond effectiveness to consider how to implement, sustain and spread successful health interventions.","authors":"Celia Laur,&nbsp;Lauren Ball,&nbsp;Heather Keller,&nbsp;Noah Ivers","doi":"10.1136/bmjnph-2020-000115","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000115","url":null,"abstract":"Health research needs to demonstrate impact. It is no longer sufficient to claim that a treatment or behavioural intervention is only ‘efficacious’. There is little sense in building evidence of efficacy without systematically figuring out how to ensure it works in the real world and ensuring it continues to work over time and across contexts. This editorial provides a brief introduction into why considering implementation, sustainability and scalability can help achieve impact in health research and encourages submission of articles to a Special Collection on Implementing Effective Interventions in Healthcare . Details for submission are included in Box 1.\u0000\u0000Box 1 \u0000### Special Collection: Implementing effective interventions in healthcare\u0000\u0000To have an impact on individual and population health, we need to consider how to implement effective interventions and practice changes. This collection encourages submission of articles about how to effectively change practice with a focus on prevention across all areas of health. Articles can be from any settings (ie, community, primary care, and hospital) and any health-related topic area, particularly nutrition and physical activity, as long as there is a focus on prevention and changing practice.\u0000\u0000Types of articles that are encouraged include:\u0000\u0000Terminology used to describe the process of putting evidence into practice varies across disciplines and over time.1 Knowledge Translation (KT) is a commonly used umbrella term that encompasses both the science of how to implement a new intervention, building on evidence from previous implementation research (implementation science), and the practice of putting interventions …","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"123-125"},"PeriodicalIF":0.0,"publicationDate":"2020-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adults. 食物与情绪:补充益生元和益生菌干预治疗成人焦虑和抑郁的综述。
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-06 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2019-000053
Sanjay Noonan, Meena Zaveri, Elaine Macaninch, Kathy Martyn
{"title":"Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adults.","authors":"Sanjay Noonan,&nbsp;Meena Zaveri,&nbsp;Elaine Macaninch,&nbsp;Kathy Martyn","doi":"10.1136/bmjnph-2019-000053","DOIUrl":"https://doi.org/10.1136/bmjnph-2019-000053","url":null,"abstract":"<p><strong>Background: </strong>A bidirectional relationship exists between the brain and the gastrointestinal tract. Foods containing bacteria that positively influence the gastrointestinal microbiome are termed, probiotics; compounds that promote the flourishing of these bacteria are termed, prebiotics. Whether microbiome influencing therapies could treat psychiatric conditions, including depression and anxiety, is an area of interest. Presently, no established consensus for such treatment exists.</p><p><strong>Methods: </strong>This systematic review analyses databases and grey literature sites to investigate pre and/or probiotics as treatments for depression and/or anxiety disorders. Articles included are from within 15 years. Pre-determined inclusion exclusion criteria were applied, and articles were appraised for their quality using a modified-CASP checklist. This review focuses specifically on quantitative measures from patients with clinical diagnoses of depression and/or anxiety disorders.</p><p><strong>Results: </strong>7 studies were identified. All demonstrated significant improvements in one or more of the outcomes measuring the of effect taking pre/probiotics compared with no treatment/placebo, or when compared to baseline measurements.</p><p><strong>Discussion: </strong>Our review suggests utilising pre/probiotic may be a potentially useful adjunctive treatment. Furthermore, patients with certain co-morbidities, such as IBS, might experience greater benefits from such treatments, given that pre/probiotic are useful treatments for other conditions that were not the primary focus of this discourse. Our results are limited by several factors: sample sizes (adequate, though not robust); short study durations, long-term effects and propensity for remission undetermined.</p><p><strong>Conclusion: </strong>Our results affirm that pre/probiotic therapy warrants further investigation. Efforts should aim to elucidate whether the perceived efficacy of pre/probiotic therapy in depression and/or anxiety disorders can be replicated in larger test populations, and whether such effects are maintained through continued treatment, or post cessation. Interventions should also be investigated in isolation, not combination, to ascertain where the observed effects are attributable to. Efforts to produce mechanistic explanations for such effect should be a priority.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"351-362"},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2019-000053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25317163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 40
Is global dietary change an effective strategy to curb climate change? 全球饮食变化是遏制气候变化的有效策略吗?
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-02 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000101
James Bradfield, Helena Trigueiro, Sumantra Ray
{"title":"Is global dietary change an effective strategy to curb climate change?","authors":"James Bradfield,&nbsp;Helena Trigueiro,&nbsp;Sumantra Ray","doi":"10.1136/bmjnph-2020-000101","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000101","url":null,"abstract":"Since the dawn of agriculture, humankind has constantly strived to improve food availability and food systems. The agricultural revolution which began in the mid-17th century and continued well into the 19th century accelerated this improvement and contributed to a growth in population and improvement in health. Since then the population has continued to rise and with it, the consequent environmental complications.\u0000\u0000Global population is now estimated at 7.7 billion people1 with a potential growth to almost 11 billion by 2100,1 underlining the challenge to feed everyone. Research has shown that we are currently not doing this—822 million people are undernourished, a fact linked with almost half of child mortality globally.2 However, the solution to this problem cannot simply be to produce more food, particularly when the Food and Agriculture Organization of the United Nations estimates that one-third of all food produced for human consumption is lost or wasted.3 The need for change is reflected in the United Nations’ Sustainable Development Goal 2.4 which aims to improve the sustainability of food production, increasing productivity while maintaining ecosystems, by 2030.\u0000\u0000While food systems must be examined, it is also worth noting the differing impacts of the types of foods that we produce. Of …","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"121-122"},"PeriodicalIF":0.0,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Using the 'shit' of the current COVID-19 crisis as fertiliser for the soil to lay the foundations of a new and sustainable era: lessons from past crises to improve the future. 利用当前COVID-19危机的“屎”作为土壤的肥料,为新的可持续时代奠定基础:从过去的危机中吸取教训,改善未来。
BMJ Nutrition, Prevention and Health Pub Date : 2020-07-02 eCollection Date: 2020-12-01 DOI: 10.1136/bmjnph-2020-000122
Tessa Roseboom
{"title":"Using the 'shit' of the current COVID-19 crisis as fertiliser for the soil to lay the foundations of a new and sustainable era: lessons from past crises to improve the future.","authors":"Tessa Roseboom","doi":"10.1136/bmjnph-2020-000122","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000122","url":null,"abstract":"<p><p>Studies of past crises have demonstrated that adverse experiences during critical periods of human development hamper the individual's ability to reach its full potential and leaves lasting marks on health, behaviour, productivity and society as a whole. The COVID-19 crisis has severely worsened the environment in which we live and in which our future generations are being shaped, and will lead to loss of future human potential and capital. It is clear that the COVID-19 pandemic does not only harm the current world population, but also affects our future, as well as that of future generations. The science of transgenerational plasticity demonstrates that investments in early life hold the promise of having beneficial effects across multiple generations. As governments are reopening societies and prioritising policies, their overarching goal should be to improve the environment in which future generations grow and develop, learn and live. This will change the lifetime trajectories of children for the better and affect future health, school success, behaviour, productivity and well-being. This prioritisation will prove to be the most effective intervention to build sustainable futures but will also yield returns many times the original investment. It is a promising way to break the intergenerational cycle of adversity and accelerate progress on achieving the Sustainable Development Goals.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"416-418"},"PeriodicalIF":0.0,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Zinc as nutritional intervention and prevention measure for COVID-19 disease. 锌作为COVID-19疾病的营养干预和预防措施
BMJ Nutrition, Prevention and Health Pub Date : 2020-06-17 eCollection Date: 2020-01-01 DOI: 10.1136/bmjnph-2020-000095
J P Mossink
{"title":"Zinc as nutritional intervention and prevention measure for COVID-19 disease.","authors":"J P Mossink","doi":"10.1136/bmjnph-2020-000095","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000095","url":null,"abstract":"<p><p>The present spread of severe acute respiratory syndrome coronavirus 2, provoking COVID-19 disease, progresses rapidly worldwide. In current absence of a curative treatment and an effective, safe vaccine, there is a pressing need to focus on identifying and correcting deficits in immune function in order to reduce risk of severe progress of the disease and to lower the number of infections and fatalities. This paper evaluates the most recent literature on zinc status related to antiviral immunity and its possible role in COVID-19. It is concluded that zinc is a critical factor for antiviral immunity. There is ample evidence suggesting that zinc depletion, also prevalent in high-income nations, compromises immune functions. Notably, major risk groups for COVID-19, the elderly, men more than women, obese individuals and patients with diabetes are all at risk of zinc deficiency. Moreover, various widely used antihypertensive drugs and statin therapy have been reported to negatively influence zinc status. As zinc depletion impairs antiviral immunity, it is hypothesised to increase susceptibility for COVID-19. Therefore, dietary preventive measures and prompt implementation of zinc supplementation for risk groups should be considered. Large-scale studies are urgently needed to investigate the role of micronutrients and antiviral immunity, in particular drug-micronutrient immunity interaction.</p>","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"111-117"},"PeriodicalIF":0.0,"publicationDate":"2020-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38640453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 45
Knowledge synthesis and translation in global food and nutrition security to evaluate and accelerate priority actions. 全球粮食和营养安全方面的知识综合和转化,以评估和加快优先行动。
BMJ Nutrition, Prevention and Health Pub Date : 2020-06-10 eCollection Date: 2020-01-01 DOI: 10.1136/bmjnph-2020-000104
Jørgen Torgerstuen Johnsen, Luke Buckner, Sumantra Ray
{"title":"Knowledge synthesis and translation in global food and nutrition security to evaluate and accelerate priority actions.","authors":"Jørgen Torgerstuen Johnsen,&nbsp;Luke Buckner,&nbsp;Sumantra Ray","doi":"10.1136/bmjnph-2020-000104","DOIUrl":"https://doi.org/10.1136/bmjnph-2020-000104","url":null,"abstract":"As highlighted in the global nutrition report (GNR) 2020, amidst the COVID-19 pandemic, there is increasing emphasis on the central role of nutrition in health and well-being.1 As the pandemic has challenged our food and health systems, the necessary measures to contain the spread of the disease have impacted and tested the food supply and agriculture sector. In the long term, if we fail to act, there will be untold impacts on food security, nutrition and the livelihoods of farmers, fishers and other workers in the food supply chain. Furthermore, the impact will be felt even harder in food security ‘hot spots’, including fragile and conflict-affected states, countries affected by multiple crises, the marginalised and vulnerable as well as countries with significant currency depreciation.2 3 The United Nations (UN) World Food Programme has warned that an estimated 265 million people could face food insecurity by the end of 2020, up from an estimated number of 135 million people before the crisis.4 However, while the pandemic poses serious challenges for the food security in the short term, it provides a unique opportunity to transform the food and agriculture sector in the long term to establish resilient food systems to …","PeriodicalId":36307,"journal":{"name":"BMJ Nutrition, Prevention and Health","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjnph-2020-000104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38738000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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