JMIR Aging最新文献

{"title":"Implementation of New Technologies in an Aged Care Social Day Program: Mixed Methods Evaluation.","authors":"Dannielle Post, Kathleen Whitson, Gaynor Parfitt","doi":"10.2196/60297","DOIUrl":"10.2196/60297","url":null,"abstract":"<p><strong>Background: </strong>Australia's aging population is looking to age in place, accessing care alternatives external to the traditional model of residential aged care facilities. This evaluation is situated in a Social Day Program, delivered by an aged care organization. It is designed to cater for people living with dementia, located in an environment equipped with new technologies including age-specific interactive computer gaming, social robots, sensory stimulation, and virtual reality. The technologies are designed to support older adults, enabling them to stay connected and maintain physical and cognitive functioning, independence, and quality of life.</p><p><strong>Objective: </strong>This project aimed to undertake a multifaceted evaluation of the implementation of the new technologies, including an exploration of the barriers and enablers to uptake. The key issue is how to enhance the potential for optimizing the use of these technologies in the Social Day Program environment, to help inform decision-making regarding the implementation of these technologies at the organization's other sites, and future investment in such technologies by aged care organizations generally.</p><p><strong>Methods: </strong>Observation of technology use within the organization was conducted over a 16-week period. Surveys and semistructured interviews were used to collect information from staff related to their experiences with the technology. Thematic analysis was used to analyze the interviews. Data were triangulated across the sample.</p><p><strong>Results: </strong>Forty-eight observation periods were completed, totaling 126.5 observation hours. Technology use by clients was observed on 24 occasions, for 22 (17.4% of the observation time) hours. Nineteen staff completed surveys. Nearly three-quarters (n=14) of the staff perceived there to be barriers to the clients' use of technology, and 18 (95%) staff reported that they assisted clients to use the technology. Ten (53%) staff reported receiving training to use the technology and feeling confident in their knowledge of the technology to assist clients in using it. Twelve staff members participated in an interview. Key themes identified from the interview data were: technology has potential but is not for everyone, incorporating the subtheme technology as a placation tool, staff knowledge and confidence, and technology functionality and support.</p><p><strong>Conclusions: </strong>This evaluation identified that technology was not being used for the purposes of enrichment or experience enhancement, nor extensively. Multiple barriers to the implementation and sustained use of the technology items were identified. Recommendations to improve implementation and promote sustained use of technology, based on the findings of this evaluation and evidence from the literature, may apply to other organizations seeking to implement these technologies in similar programs.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e60297"},"PeriodicalIF":5.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to and Facilitators of Implementing Overnight Nursing Teleconsultation in Small, Rural Long-Term Care Facilities: Qualitative Interview Study.","authors":"Veronique Nabelsi, Véronique Plouffe, Marie Chantal Leclerc","doi":"10.2196/71950","DOIUrl":"10.2196/71950","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Teleconsultation has expanded rapidly in recent years, especially during the COVID-19 pandemic, and has become standard practice among physicians. The benefits of teleconsultation, namely, improving access to care, ensuring continuity and quality of care, increasing patient satisfaction, and reducing costs and wait times, are well documented. However, its use in nursing practice, especially in long-term care settings, remains underresearched despite its significant transformative potential, particularly in resource-limited and rural settings, where it could address major challenges such as nursing shortages and access to care.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to identify barriers to and facilitators of implementing overnight nursing teleconsultation in rural residential and long-term care centers in Quebec, Canada (centres d'hébergement et de soins de longue durée [CHSLDs]), with ≤50 beds.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A 6-month pilot project was rolled out sequentially in 3 rural CHSLDs in 2 administrative regions of Quebec between July 2022 and March 2023. A total of 38 semistructured interviews were conducted with managers (n=27, 71%), nursing staff members (n=9, 24%), and resident committee presidents (n=2, 5%) between February 2023 and July 2023.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study identified several barriers to the implementation of teleconsultation. The main barriers reported included union opposition (managers: 23/27, 85%), network instability (resident committee presidents: 2/2, 100%), limited technology skills (nursing staff members: 7/9, 78%), a perceived increase in workload (nursing staff members: 8/9, 89%; resident committee presidents: 2/2, 100%), and a low volume of teleconsultations (nursing staff members: 8/9, 89%). Despite the barriers, participants also identified key facilitators. These included the care setting (nursing staff members: 9/9, 100%; managers: 21/27, 78%), buy-in from senior management and managers (managers: 27/27, 100%; resident committee presidents: 2/2, 100%), collaboration between the departments (nursing staff members: 9/9, 100%), nursing staff motivation (nursing staff members: 9/9, 100%), and improvements in professional practices (nursing staff members: 8/9, 89%). Finally, the relative benefits of teleconsultation, such as enhanced mutual vision, faster assessment of clinical situations, improved resident care management quality, and greater flexibility and safety, were unanimously recognized (38/38, 100%) as contributing to its acceptability and potential for success.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study provides an in-depth understanding of the barriers to and facilitators of implementing overnight nursing teleconsultation in small rural CHSLDs. This constitutes a sound basis for developing tailored strategies aimed at overcoming identified barriers and optimizing facilitators. The results also provide practical guidelines for decision","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e71950"},"PeriodicalIF":5.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Older Adults' Perception of the Age-Friendliness of Their Environment and the Impact of Loneliness, Technology Use, and Mobility: Quantitative Analysis.","authors":"Eric Balki, Niall Hayes, Carol Holland","doi":"10.2196/67242","DOIUrl":"10.2196/67242","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization's (WHO) publication on age-friendly environments (AFEs) imagines future cities to become more age-friendly to harness the latent potential of older adults, especially those who have restricted mobility. AFE has important implications for older adults in maintaining social connections, independence, and successful aging-in-place. However, technology is notably absent in the 8 intersecting domains of AFEs that the WHO imagines improve older adult well-being, and we investigated whether technology should form a ninth domain. While mobility was severely restricted, the COVID-19 pandemic provided an opportunity to test how older adults' perceptions of their AFE changed and what role technology was playing.</p><p><strong>Objective: </strong>This study examined how life-space mobility (LSM), a concept for assessing patterns of functional mobility over time, and loneliness impacted perceived AFEs and the moderating effect of technology. It also explores whether technology should play a greater role as the ninth domain of the WHO's imagination of the AFE of the future.</p><p><strong>Methods: </strong>In this cross-sectional quantitative observation study, data from 92 older adults aged 65-89 years were collected in England from March 2020 to June 2021 during the COVID-19 pandemic. The Life-space Questionnaire, Technology Experience Questionnaire, UCLA (University of California, Los Angeles) Loneliness Scale, and age-friendly environment assessment tool were used. Correlation and moderation analyses were used to investigate relationships between variables.</p><p><strong>Results: </strong>Most participants (86/92, 93%) had not left their immediate town in the previous 4 weeks before the interview. Restricted LSM was positively correlated to the age-friendly environment assessment tool, that is, rising physical isolation was linked to a better perception of AFEs; however, we discovered this result was due to the moderating impact of increased use of technology, and that restricted LSM actually had a negative effect on AFEs. Loneliness was correlated negatively with the perception of AFEs, but technology use was found to moderate the impact of loneliness.</p><p><strong>Conclusions: </strong>Pandemic-related LSM restrictions impacted perceived AFEs and loneliness negatively, but technology played a moderating role. The findings demonstrate that technology could be considered as a ninth domain in the WHO's assessment of AFEs for older adults and that there is a need for its explicit acknowledgment.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e67242"},"PeriodicalIF":5.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online Communities as a Support System for Alzheimer Disease and Dementia Care: Large-Scale Exploratory Study.","authors":"Sidharth Kaliappan, Chunyu Liu, Yoshee Jain, Ravi Karkar, Koustuv Saha","doi":"10.2196/68890","DOIUrl":"10.2196/68890","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer disease (AD) is the leading type of dementia, demanding comprehensive understanding and intervention strategies. In the United States, where over 6 million people are impacted, the prevalence of AD and related dementias (AD/ADRD) presents a growing public health challenge. However, individuals living with AD/ADRD and their caregivers frequently express feelings of marginalization, describing interactions characterized by perceptions of patient infantilization and a lack of respect.</p><p><strong>Objective: </strong>This study aimed to address 2 key research questions (RQs). For RQ1, we investigated the needs and concerns expressed by participants in online social communities focused on AD/ADRD, specifically on 2 platforms-Reddit's r/Alzheimers and ALZConnected. For RQ2, we examined the prevalence and distribution of social support corresponding to these needs and concerns, and the association between these needs and received support.</p><p><strong>Methods: </strong>We collected 13,429 posts and comments from the r/Alzheimers subreddit spanning July 2014 to November 2023, and 90,113 posts and comments from ALZConnected between December 2020 (the community's earliest post) and November 2023. We conducted topic modeling using latent Dirichlet allocation (LDA), followed by labeling to identify the major topical themes of discussions. We used transfer learning classifiers to identify the occurrences of emotional support (ES) and informational support (IS) in the comments (or responses) in the discussions. We built regression models to examine how various topical themes are associated with the kinds of support received.</p><p><strong>Results: </strong>Our analysis revealed a diverse range of topics reflecting community members' varying needs and concerns of individuals affected by AD/ADRD. These themes encapsulate the primary discussions within the online communities: memory care, nursing and caregiving, gratitude and acknowledgment, and legal and financial considerations. Our findings indicated a higher prevalence of IS compared to ES. Regression models revealed that ES primarily occurs in posts relating to nursing and caring, and IS primarily occurs in posts concerning medical conditions and diagnosis, legal and financial, and caregiving at home.</p><p><strong>Conclusions: </strong>This study reveals that online communities dedicated to AD/ADRD support engage in discussions on a wide range of topics, such as memory care, nursing, caregiving, and legal and financial challenges. The findings shed light on the key pain points and concerns faced by individuals managing AD/ADRD in their households, revealing how they leverage online platforms for guidance and support. These insights underscore the need for targeted institutional and social interventions to address the specific needs of AD/ADRD patients, caregivers, and other family members.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e68890"},"PeriodicalIF":5.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual Response Problems and Their Correlates Among Older Adults From the Sexual Well-Being (SWELL) Study in China: Multicenter Cross-Sectional Study.","authors":"Bingyu Liang, Chen Xu, Bingyi Wang, Xinyi Li, Xin Peng, Ying Wang, Hui Li, Yong Lu, Xiaopei Shen, Lin Ouyang, Guohui Wu, Maohe Yu, Jiewei Liu, Xiaojun Meng, Yong Cai, Huachun Zou","doi":"10.2196/66772","DOIUrl":"https://doi.org/10.2196/66772","url":null,"abstract":"<p><strong>Background: </strong>Sexual response problems among older adults are not an inevitable consequence of aging but rather a response to sexual health. However, there is a lack of recent and multicenter data on this issue in China.</p><p><strong>Objective: </strong>This study aims to assess the prevalence of sexual response problems and their correlates among older adults.</p><p><strong>Methods: </strong>A multicenter cross-sectional study on sexual well-being was conducted among individuals aged more than 50 years in China between June 2020 and December 2022. Data on sociodemographics, physical health, psychological health, and sexual response problems were collected through face-to-face interviews. We included sexually active older adults who reported either vaginal, oral, or anal sex in the past 12 months for this study. Sexual response problems included a lack of interest or enjoyment in sex; feeling anxious, having pain, or no excitement during sex; no desire or orgasms; and the lack of lubrication in sex. The stepwise logistic regression models were used to examine the correlates of sexual response problems.</p><p><strong>Results: </strong>A total of 1317 sexually active older adults (842 men, 475 women) were included. Older women reported a higher prevalence of sexual response problems than older men (52.0% [247/475] vs 43.1% [363/842]). Common factors associated with at least one of the sexual response problems included living in rural areas (men: adjusted odds ratio [aOR]=0.31, 95% CI 0.22-0.43; women: aOR=0.29, 95% CI 0.19-0.43) and abnormal BMI (aOR=men: 1.52, 95% CI1.11-2.07; women: aOR=2.19, 95% CI 1.47-3.28). Among older men, sleep quality (aOR=1.87, 95% CI 1.30-2.68), emotional connection with sex partners during sexual intercourse (aOR=0.69, 95% CI 0.50-0.96), frequently experienced fatigue (aOR=2.47, 95% CI 1.59-3.90), anxiety (aOR=4.26, 95% CI 1.12-21.27), and seeking professional help for sex life (aOR=1.58, 95% CI 1.14-2.21) were associated with sexual response problems. Among older women, sexual response problems were associated with a lack of physical exercise (aOR=1.69, 95% CI 1.13-2.54), poor sex-partner relationships (aOR=1.70, 95% CI 1.12-2.60), and depressive symptoms (aOR=3.18, 95% CI 1.18-10.24).</p><p><strong>Conclusions: </strong>Sexual response problems are common among older adults. These problems were associated with adverse physical health, mental health, and poor sex-partner relationships. These findings highlight the importance for health care providers to take into account the physical and psychological health of older adults, as well as the quality of their relationships with sexual partners when diagnosing and addressing sexual response problems.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e66772"},"PeriodicalIF":5.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Machine Learning to Predict Cognitive Decline in Older Adults From the Chinese Longitudinal Healthy Longevity Survey: Model Development and Validation Study.","authors":"Hao Ren, Yiying Zheng, Changjin Li, Fengshi Jing, Qiting Wang, Zeyu Luo, Dongxiao Li, Deyi Liang, Weiming Tang, Li Liu, Weibin Cheng","doi":"10.2196/67437","DOIUrl":"https://doi.org/10.2196/67437","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment, indicative of Alzheimer disease and other forms of dementia, significantly deteriorates the quality of life of older adult populations and imposes considerable burdens on families and health care systems worldwide. The early identification of individuals at risk for cognitive impairment through a convenient and rapid method is crucial for the timely implementation of interventions.</p><p><strong>Objective: </strong>The objective of this study was to explore the application of machine learning (ML) to integrate blood biomarkers, life behaviors, and disease history to predict the decline in cognitive function.</p><p><strong>Methods: </strong>This approach uses data from the Chinese Longitudinal Healthy Longevity Survey. A total of 2688 participants aged 65 years or older from the 2008-2009, 2011-2012, and 2014 Chinese Longitudinal Healthy Longevity Survey waves were included, with cognitive impairment defined as a Mini-Mental State Examination (MMSE) score below 18. The dataset was divided into a training set (n=1331), an internal test set (n=333), and a prospective validation set (n=1024). Participants with a baseline MMSE score of less than 18 were excluded from the cohort to ensure a more accurate assessment of cognitive function. We developed ML models that integrate demographic information, health behaviors, disease history, and blood biomarkers to predict cognitive function at the 3-year follow-up point, specifically identifying individuals who are at risk of experiencing significant declines in cognitive function by that time. Specifically, the models aimed to identify individuals who would experience a significant decline in their MMSE scores (less than 18) by the end of the follow-up period. The performance of these models was evaluated using metrics including accuracy, sensitivity, and the area under the receiver operating characteristic curve.</p><p><strong>Results: </strong>All ML models outperformed the MMSE alone. The balanced random forest achieved the highest accuracy (88.5% in the internal test set and 88.7% in the prospective validation set), albeit with a lower sensitivity, while logistic regression recorded the highest sensitivity. SHAP (Shapley Additive Explanations) analysis identified instrumental activities of daily living, age, and baseline MMSE scores as the most influential predictors for cognitive impairment.</p><p><strong>Conclusions: </strong>The incorporation of blood biomarkers, along with demographic, life behavior, and disease history into ML models offers a convenient, rapid, and accurate approach for the early identification of older adult individuals at risk of cognitive impairment. This method presents a valuable tool for health care professionals to facilitate timely interventions and underscores the importance of integrating diverse data types in predictive health models.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e67437"},"PeriodicalIF":5.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of the Use of Mobile Apps to Assess Sleep-Dependent Memory in Older Adults With Subjective and Objective Cognitive Impairment: Focus Group Approach.","authors":"Aaron Lam, Simone Simonetti, Angela D'Rozario, David Ireland, DanaKai Bradford, Jurgen Fripp, Sharon L Naismith","doi":"10.2196/68147","DOIUrl":"https://doi.org/10.2196/68147","url":null,"abstract":"<p><strong>Background: </strong>Sleep-dependent memory (SDM) is the phenomenon where newly obtained memory traces are consolidated from short-term memory stores to long-term memory, underpinning memory for daily life. Administering SDM tasks presents considerable challenges, particularly for older adults with memory concerns, due to the need for sleep laboratories and research staff being present to administer the task. In response, we have developed a prototype mobile app aimed at automating the data collection process.</p><p><strong>Objective: </strong>This study investigates the perspectives of older adults, with subjective or objective cognitive impairment, regarding barriers and facilitators to using a new mobile app for at-home assessment of SDM.</p><p><strong>Methods: </strong>In total, 11 participants aged 50 years and older were recruited from the Healthy Brain Ageing memory clinic, a specialized research memory clinic that focuses on the assessment and early intervention of cognitive decline. Two focus groups were conducted and thematically analyzed using NVivo (version 13; Lumivero).</p><p><strong>Results: </strong>On average, participants were aged 68.5 (SD 5.1) years, and 4/11 were male. Eight participants had subjective cognitive impairment, and 3 participants had mild cognitive (objective) impairment. Two main themes emerged from the focus groups, shedding light on participants' use of mobile phones and the challenges and facilitators associated with transitioning from traditional laboratory-based assessments to home assessments. These challenges include maintaining accurate data, engaging with humans versus robots, and ensuring accessibility and task compliance. Additionally, potential solutions to these challenges were identified.</p><p><strong>Conclusions: </strong>Our findings underscore the importance of app flexibility in accommodating diverse user needs and preferences as well as in overcoming barriers. While some individuals required high-level assistance, others expressed the ability to navigate the app independently or with minimal support. In conclusion, older adults provided valuable insights into the app modifications, user needs, and accessibility requirements enabling home-based SDM assessment.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e68147"},"PeriodicalIF":5.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Within-Session Digital Motor Skill Acquisition and Alzheimer Disease Risk Factors Among the MindCrowd Cohort: Cross-Sectional Descriptive Study.","authors":"Andrew Hooyman, Matt J Huentelman, Matt De Both, Lee Ryan, Kevin Duff, Sydney Y Schaefer","doi":"10.2196/67298","DOIUrl":"https://doi.org/10.2196/67298","url":null,"abstract":"<p><strong>Background: </strong>Previous research has shown that in-lab motor skill acquisition (supervised by an experimenter) is sensitive to biomarkers of Alzheimer disease (AD). However, remote unsupervised screening of AD risk through a skill-based task via the web has the potential to sample a wider and more diverse pool of individuals at scale.</p><p><strong>Objective: </strong>The purpose of this study was to examine a web-based motor skill game (\"Super G\") and its sensitivity to risk factors of AD (eg, age, sex, APOE ε4 carrier status, and verbal learning deficits).</p><p><strong>Methods: </strong>Emails were sent to 662 previous MindCrowd participants who had agreed to be contacted for future research and have their APOE ε4 carrier status recorded and those who were at least 45 years of age or older. Participants who chose to participate were redirected to the Super G site where they completed the Super G task using their personal computer remotely and unsupervised. Once completed, different Super G variables were derived. Linear and logistic multivariable regression was used to examine the relationship between available AD risk factors (age, sex, APOE ε4 carrier status, and verbal learning) and distinct Super G performance metrics.</p><p><strong>Results: </strong>Fifty-four participants (~8% response rate) from the MindCrowd web-based cohort (mean age of 62.39 years; 39 females; and 23 APOE ε4 carriers) completed 75 trials of Super G. Results show that Super G performance was significantly associated with each of the targeted risk factors. Specifically, slower Super G response time was associated with being an APOE ε4 carrier (odds ratio 0.12, 95% CI 0.02-0.44; P=.006), greater Super G time in target (TinT) was associated with being male (odds ratio 32.03, 95% CI 3.74-1192,61; P=.01), and lower Super G TinT was associated with greater age (β -3.97, 95% CI -6.64 to -1.30; P=.005). Furthermore, a sex-by-TinT interaction demonstrated a differential relationship between Super G TinT and verbal learning depending on sex (βmale:TinT 6.77, 95% CI 0.34-13.19; P=.04).</p><p><strong>Conclusions: </strong>This experiment demonstrated that this web-based game, Super G, has the potential to be a skill-based digital biomarker for screening of AD risk on a large scale with relatively limited resources.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e67298"},"PeriodicalIF":5.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Sleep Duration and Cognitive Frailty in Older Chinese Adults: Prospective Cohort Study.","authors":"Ruixue Cai, Jianqian Chao, Chenlu Gao, Lei Gao, Kun Hu, Peng Li","doi":"10.2196/65183","DOIUrl":"10.2196/65183","url":null,"abstract":"<p><strong>Background: </strong>Disturbed sleep patterns are common among older adults and may contribute to cognitive and physical declines. However, evidence for the relationship between sleep duration and cognitive frailty, a concept combining physical frailty and cognitive impairment in older adults, is lacking.</p><p><strong>Objective: </strong>This study aimed to examine the associations of sleep duration and its changes with cognitive frailty.</p><p><strong>Methods: </strong>We analyzed data from the 2008-2018 waves of the Chinese Longitudinal Healthy Longevity Survey. Cognitive frailty was rendered based on the modified Fried frailty phenotype and Mini-Mental State Examination. Sleep duration was categorized as short (<6 h), moderate (6-9 h), and long (>9 h). We examined the association of sleep duration with cognitive frailty status at baseline using logistic regressions and with the future incidence of cognitive frailty using Cox proportional hazards models. Restricted cubic splines were used to explore potential nonlinear associations.</p><p><strong>Results: </strong>Among 11,303 participants, 1298 (11.5%) had cognitive frailty at baseline. Compared to participants who had moderate sleep duration, the odds of having cognitive frailty were higher in those with long sleep duration (odds ratio 1.71, 95% CI 1.48-1.97; P<.001). A J-shaped association between sleep duration and cognitive frailty was also observed (P<.001). Additionally, during a mean follow-up of 6.7 (SD 2.6) years among 5201 participants who were not cognitively frail at baseline, 521 (10%) participants developed cognitive frailty. A higher risk of cognitive frailty was observed in participants with long sleep duration (hazard ratio 1.32, 95% CI 1.07-1.62; P=.008).</p><p><strong>Conclusions: </strong>Long sleep duration was associated with cognitive frailly in older Chinese adults. These findings provide insights into the relationship between sleep duration and cognitive frailty, with potential implications for public health policies and clinical practice.</p>","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e65183"},"PeriodicalIF":5.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Machine Learning Models for Frailty Classification of Older Adults in Northern Thailand: Model Development and Validation Study.","authors":"Natthanaphop Isaradech, Wachiranun Sirikul, Nida Buawangpong, Penprapa Siviroj, Amornphat Kitro","doi":"10.2196/75690","DOIUrl":"https://doi.org/10.2196/75690","url":null,"abstract":"","PeriodicalId":36245,"journal":{"name":"JMIR Aging","volume":"8 ","pages":"e75690"},"PeriodicalIF":5.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}