{"title":"Corrigendum to Cervical cerclage for short cervix at 24 to 26 weeks of gestation: systematic review and meta-analysis of randomized controlled trials using individual patient-level data American Journal of Obstetrics & Gynecology MFM Volume 5, Issue 6, June 2023, 100930","authors":"Moti Gulersen MD, MSc , Erez Lenchner PhD , Kypros H. Nicolaides MD , Katsufumi Otsuki MD , Orion A. Rust MD , Sietske Althuisius MD , Eran Bornstein MD , Vincenzo Berghella MD","doi":"10.1016/j.ajogmf.2024.101411","DOIUrl":"10.1016/j.ajogmf.2024.101411","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 8","pages":"Article 101411"},"PeriodicalIF":3.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Whitley MD , Julia Burd MD , Michelle Doering MLIS , Amanda Zofkie MD , Antonina Frolova MD, PHD , Jeannie Kelly MD, MS , Nandini Raghuraman MD, MSCI
{"title":"Postpartum diuretic administration and hospital readmission: a systematic review and meta-analysis","authors":"Julia Whitley MD , Julia Burd MD , Michelle Doering MLIS , Amanda Zofkie MD , Antonina Frolova MD, PHD , Jeannie Kelly MD, MS , Nandini Raghuraman MD, MSCI","doi":"10.1016/j.ajogmf.2025.101738","DOIUrl":"10.1016/j.ajogmf.2025.101738","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to determine if postpartum administration of loop diuretic therapy among patients at risk of or diagnosed with a hypertensive disorder of pregnancy impacts the rate of hospital readmission compared to typical care.</div></div><div><h3>Data sources</h3><div>This study was a systematic review and meta-analysis of randomized controlled trials (RCTs). A research librarian performed a database search using a combination of standardized terms and keywords related to postpartum hypertension and loop diuretics from database inception until February 2025. This study was registered in PROSPERO (registration number CRD42024546708).</div></div><div><h3>Study eligibility criteria</h3><div>RCTs that compared outcomes between administration of loop diuretic therapy and routine care among postpartum patients at risk of or diagnosed with a hypertensive disorder of pregnancy were included. Inclusion criteria and diagnosis of hypertensive disorder of pregnancy were defined per each trial’s protocol. Nonrandomized trials, quasi-randomized trials, and animal models were excluded. All titles and abstracts obtained through the search were independently assessed by two reviewers using the screening tool in Covidence, and full-text articles were reviewed. A total of 10 articles met inclusion criteria and were included in the systematic review and meta-analysis.</div></div><div><h3>Study appraisal and synthesis methods</h3><div>Two independent investigators independently abstracted data using a standardized template created in Covidence. The primary outcome was the rate of hospital readmission. Secondary maternal outcomes included readmission for hypertension, mean postpartum blood pressure, and severe maternal morbidity. The risk of bias in each study was assessed using the guidelines outlined in the Cochrane Handbook for Systematic Reviews of Interventions. Heterogeneity was measured using Higgins <em>I</em><sup>2</sup>. Meta-analysis was performed in Review Manager 5.4.1 to produce summary treatment effects in terms of relative risk (RR) or mean difference with 95% confidence intervals (CIs).</div></div><div><h3>Results</h3><div>Ten RCTs, including 1401 patients, were included in the meta-analysis. The rate of hospital readmission, reported in 3 studies, did not differ between administration of loop diuretic therapy and routine care (RR=2.00; 95% CI, 0.71–5.67). The rate of readmission for hypertension also did not differ between groups (3 studies, RR=0.69; 95% CI, 0.35–1.36). Additional antihypertensive requirements were lower in patients who received diuretics (6 studies, RR=0.47; 95% CI, 0.26–0.85). There were no differences in any other secondary maternal outcomes, including discharge on antihypertensives (8 studies, RR=1.00; 95% CI, 0.91–1.11), hospital length of stay (6 studies, mean difference=0.15; 95% CI, –0.18 to 0.48), or severe maternal morbidity.</div></div><div><h3>Conclusion</h3><div>There is insufficient evidence to ","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101738"},"PeriodicalIF":3.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of self-care interventions for the prevention of type 2 diabetes among women with previous gestational diabetes: a systematic review and meta-analysis","authors":"Sho Katsuragawa MD, MPH , Thuy Mai MPH , Annie R.A. McDougall PhD , Lorena Romero MBIT , Joshua P. Vogel PhD , Maureen Makama PhD","doi":"10.1016/j.ajogmf.2025.101731","DOIUrl":"10.1016/j.ajogmf.2025.101731","url":null,"abstract":"<div><h3>Objective</h3><div>Gestational diabetes (GDM) is associated with an increased risk of developing type 2 diabetes later in life. Self-care interventions are known to prevent type 2 diabetes in high-risk populations. This systematic review aimed to investigate whether self-care interventions can prevent type 2 diabetes among women with previous GDM.</div></div><div><h3>Data sources</h3><div>A systematic search of MEDLINE, Embase, Cochrane Library, CINAHL, and PsycINFO was conducted on December 2, 2024.</div></div><div><h3>Study eligibility criteria</h3><div>Randomised, cluster-randomised, and non-randomised controlled trials that compared the effects of self-care interventions with standard/usual care or no intervention for preventing type 2 diabetes among women with previous GDM were included. The primary outcomes were the incidence of type 2 diabetes, the composite incidence of any type of diabetes, glycated hemoglobin, fasting blood glucose, blood glucose level 2 hours after the oral glucose tolerance test, and body weight.</div></div><div><h3>Study appraisal and synthesis methods</h3><div>Risk of bias for included studies was assessed using the Cochrane risk-of-bias tool (ROB2) or the Risk of Bias In Non-Randomized Studies of Interventions tool (ROBINS-I). Random effects models were employed for meta-analyses. The certainty of evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation approach.</div></div><div><h3>Results</h3><div>The search identified 35 trials including 6624 women. Only one randomised trial (<em>n</em>=1601) reported the incidence of type 2 diabetes, indicating that the lifestyle intervention focusing on diet and physical activity may have little to no effect (hazard ratio 0.89 [95% confidence interval 0.65–1.22], low certainty of evidence). The effects of self-care interventions on the other primary outcomes—composite incidence of any type of diabetes (three trials), glycated hemoglobin (three trials), fasting blood glucose (11 trials), blood glucose level 2 hours after the oral glucose tolerance test (six trials), and body weight (18 trials) were uncertain (very low certainty of evidence). Downgrading of the certainty of evidence was predominantly due to high risk of bias, imprecision, and inconsistency.</div></div><div><h3>Conclusion</h3><div>Available evidence on the effect of self-care interventions for the prevention of type 2 diabetes among women with previous GDM is insufficient to draw strong conclusions, necessitating further research.</div></div>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101731"},"PeriodicalIF":3.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to editor regarding Acupuncture before planned admission for induction of labor (ACUPUNT study): a randomized controlled trial","authors":"Han Zhang PhD, Yang Yu MD, Yi-Jie Hu MD","doi":"10.1016/j.ajogmf.2025.101733","DOIUrl":"10.1016/j.ajogmf.2025.101733","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101733"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The argument for normalizing nonsevere pregnancy hypertension : let us not repeat the CHIPS to CHAP delay","authors":"Laura A. Magee MD, Peter von Dadelszen DPhil","doi":"10.1016/j.ajogmf.2025.101702","DOIUrl":"10.1016/j.ajogmf.2025.101702","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101702"},"PeriodicalIF":3.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline Fryar MD, MPH , Tingting Liu BS , Neill Bates MPH , Dmitry Tumin PhD , Kelly Bear DO , Rachel Taylor MD , James L. Whiteside MD
{"title":"Antenatal corticosteroid administration among infants born at 22 weeks’ gestation after a practice advisory endorsing its consideration","authors":"Caroline Fryar MD, MPH , Tingting Liu BS , Neill Bates MPH , Dmitry Tumin PhD , Kelly Bear DO , Rachel Taylor MD , James L. Whiteside MD","doi":"10.1016/j.ajogmf.2025.101728","DOIUrl":"10.1016/j.ajogmf.2025.101728","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>In response to an accumulation of evidence supporting antenatal steroid administration at 22 weeks of gestation with planned neonatal resuscitation, the American College of Obstetricians and Gynecologists, alongside the Society for Maternal-Fetal Medicine, published a clinical practice advisory recommending consideration of antenatal steroids at 22 weeks of gestation in September 2021.</div></div><div><h3>OBJECTIVE</h3><div>This study aimed to determine whether the 2021 American College of Obstetricians and Gynecologists practice advisory was associated with an increase in the use of antenatal corticosteroids among infants born at 22 weeks of gestation.</div></div><div><h3>STUDY DESIGN</h3><div>This retrospective, secondary analysis used data from the United States Centers for Disease Control and Prevention’s National Vital Statistics System from 2017 to 2023. The primary outcome was antenatal steroid use as recorded on the birth certificate, and our main exposure was the birth year that was dichotomized as after (2022–2023) vs before (2017–2020) practice guideline implementation. The chi-square and rank-sum tests were used to compare gestational age before and after the implementation of the guideline, respectively. A multivariate regression using a difference-in-difference specification model was used to determine antenatal steroid use among births at 22 and 24 to 25 weeks of gestation, and a separate multivariate model was included using live births at 23 weeks of gestation for sensitivity analysis.</div></div><div><h3>RESULTS</h3><div>After applying our exclusion criteria, a total of 11,203 live births in the United States at 22 to 25 weeks of gestation between 2017–2020 and 2022–2023 were available for analysis. Our bivariate analysis indicated an increased use of antenatal steroids in live births at 22 weeks of gestation from 48% (178/368) before to 61% (216/356) after the American College of Obstetricians and Gynecologists guideline implementation (<em>P</em>=.001). However, steroid administration did not change at 23 weeks of gestation (<em>P</em>=.385), with only a slight increase from 63% to 66% at 24 to 25 weeks of gestation (<em>P</em>=.033) in our bivariate analysis. Our multivariate analysis found similar patterns, with 65% higher odds of steroid use in births at 22 weeks of gestation (<em>P</em>=.001), with no significant change in births at 24 to 25 weeks of gestation (<em>P</em>=.061). Similar results were found in our sensitivity analysis of births at 22 weeks of gestation (<em>P</em>=.001), but no significant association was identified for births at 23 weeks of gestation (<em>P</em>=.710).</div></div><div><h3>CONCLUSION</h3><div>The recommendation by the American College of Obstetricians and Gynecologists to consider antenatal corticosteroid administration in preterm deliveries at 22 weeks of gestation has led to an increase in this clinical practice. This significant association highlights the valu","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101728"},"PeriodicalIF":3.8,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aya Mudrik BS , Romi Levy BS , Alessandro Petrecca MD , Moti Gulersen MD, MSc , Suneet P. Chauhan MD, Hon DSc , Offer Erez MD, MBA , Misgav Rottenstreich MD, MBA
{"title":"Guidelines on cerclage placement: a comparative systematic review","authors":"Aya Mudrik BS , Romi Levy BS , Alessandro Petrecca MD , Moti Gulersen MD, MSc , Suneet P. Chauhan MD, Hon DSc , Offer Erez MD, MBA , Misgav Rottenstreich MD, MBA","doi":"10.1016/j.ajogmf.2025.101727","DOIUrl":"10.1016/j.ajogmf.2025.101727","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>Variability among professional society guidelines for cervical and abdominal cerclage may lead to inconsistent clinical practice and outcomes.</div></div><div><h3>OBJECTIVE</h3><div>This study aimed to systematically identify, summarize, and compare professional medical-society guidelines on cervical and abdominal cerclage.</div></div><div><h3>STUDY DESIGN</h3><div>Guidelines were independently screened and selected by 2 reviewers. Quality was assessed using the AGREE II instrument. Data were extracted into a standardized form and synthesized narratively, focusing on comparing recommendations regarding indications, contraindications, timing, technique, and perioperative management of cerclage placement.</div></div><div><h3>RESULTS</h3><div>Twenty guidelines from ten professional societies were included. Consensus existed on several key indications, including history-indicated cerclage for ≥3 second-trimester losses, ultrasound-indicated cerclage for cervical lengths under 10 mm, and abdominal cerclage in cases of prior transvaginal cerclage failure or insufficient cervical tissue. However, disagreements remain. For instance, ACOG (American College of Obstetricians and Gynecologists) recommends considering cerclage after one loss, whereas most guidelines require 3. There is also variation regarding the timing of physical examination cerclage beyond 24 weeks, with NICE (National Institute for Health and Care Excellence) extending the window to 28 weeks. Additionally, recommendations diverge on cerclage for prolapsed membranes, with some guidelines advising against the procedure due to a high risk of failure, while others support considering it.</div></div><div><h3>CONCLUSION</h3><div>Guidelines agree on history-indicated cerclage for ≥3 second-trimester losses, ultrasound-indicated cerclage for cervical lengths under 10 mm, and abdominal cerclage in cases of prior transvaginal cerclage failure or insufficient cervical tissue. While agreement exists on key indications and contraindications, notable divergences remain in certain recommendations. This review emphasizes the need for congruent recommendations to enhance consistency.</div></div>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101727"},"PeriodicalIF":3.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dante Varotsis MD , Jordan Beacham BS , Julie Gomez MD , Zain Hannan BA , Rupsa C. Boelig MD , Vincenzo Berghella MD , Moti Gulersen MSc
{"title":"Stillbirth is associated with postpartum severe maternal morbidity compared with gestational age matched and term live births","authors":"Dante Varotsis MD , Jordan Beacham BS , Julie Gomez MD , Zain Hannan BA , Rupsa C. Boelig MD , Vincenzo Berghella MD , Moti Gulersen MSc","doi":"10.1016/j.ajogmf.2025.101725","DOIUrl":"10.1016/j.ajogmf.2025.101725","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>The rates of severe maternal morbidity in the United States continue to increase. The American College of Obstetricians and Gynecologists recommends close postpartum follow-up for patients at increased risk for severe maternal morbidity and mortality, such as those who suffer from preeclampsia or hypertension. Data on the association between stillbirth and severe maternal morbidity are limited.</div></div><div><h3>OBJECTIVE</h3><div>This study aimed to evaluate the association between stillbirth and severe maternal morbidity in comparison with gestational age–matched and term live births.</div></div><div><h3>STUDY DESIGN</h3><div>This was a multicenter, retrospective cohort study that was performed at 3 centers within a hospital system from 2017 to 2023. Severe maternal morbidity was defined with guidance from the indicators outlined by the Centers for Disease Control and Prevention. The inclusion criteria for the stillbirth group were delivery of a fetus that showed no signs of life at 20 weeks’ gestation or later. Cases with antepartum preeclampsia, multiple gestations, maternal age less than 18 years, duplicate records, and voluntary terminations of the pregnancy after 20 weeks’ gestation were excluded. We selected gestational age- and term-matched live births as the control groups. A logistic regression analysis was performed to evaluate the odds of the composite severe maternal morbidity in stillbirths vs gestational age–matched and term-matched live births, separately, with adjustment for potential confounders. The data were presented as the adjusted odds ratios with 95% confidence intervals, and statistical significance was set at a <em>P</em> value of <.05.</div></div><div><h3>RESULTS</h3><div>Of the 29,060 deliveries during the study period, there were 129 (0.44%) stillbirths. Stillbirth was associated with significantly higher odds of severe maternal morbidity than term (adjusted odds ratio, 4.35; 95% confidence interval, 1.75–10.84) and gestational age matched livebirths (adjusted odds ratio, 3.39; 95% confidence interval, 1.72–6.66). There was no significant difference in the rate of postpartum hemorrhage when stillbirths were compared with gestational age–matched live births (10.1% vs 7.3%; <em>P</em>=.42), however, there were significantly more transfusions needed in the stillbirth group (10.1% vs 1.6%; <em>P</em>=.017). When compared with the term live births, there were significantly more transfusions (10.1% vs 1.6%; <em>P</em><.001), intensive care admissions (2.3% vs 0%; <em>P</em>=.007), postpartum preeclampsia (2.3% vs 0%; <em>P</em>=.007), and sepsis (2.3% vs 0%; <em>P</em>=.007).</div></div><div><h3>CONCLUSION</h3><div>Stillbirth is associated with an increased risk for severe maternal morbidity when compared with gestational age- and term-matched live births. Increased postpartum surveillance should be implemented into practice, and preventative interventions, such as tranexamic acid admin","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 9","pages":"Article 101725"},"PeriodicalIF":3.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Whitley MD, Karen George MD, MPH, Jeannie C. Kelly MD, MS, Megan L. Lawlor MD, Erika Banks MD, Phillip Ma MD, Jillian Catalanotti MD, MPH
{"title":"The state of residency training in treatment of opioid use disorder in obstetrics and gynecology","authors":"Julia Whitley MD, Karen George MD, MPH, Jeannie C. Kelly MD, MS, Megan L. Lawlor MD, Erika Banks MD, Phillip Ma MD, Jillian Catalanotti MD, MPH","doi":"10.1016/j.ajogmf.2025.101723","DOIUrl":"10.1016/j.ajogmf.2025.101723","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 8","pages":"Article 101723"},"PeriodicalIF":3.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter in reply re: comparative effectiveness of low molecular weight heparin on live birth for recurrent spontaneous abortion: systematic review and network meta-analysis","authors":"Wenrui Huang MD, PhD, Xuelian Du MD, PhD","doi":"10.1016/j.ajogmf.2025.101720","DOIUrl":"10.1016/j.ajogmf.2025.101720","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 8","pages":"Article 101720"},"PeriodicalIF":3.8,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}