Katherine Klein, Herney Andrés García-Perdomo, Cristhiam M Rojas Hernandez
{"title":"Navigating Limited Evidence on Thromboprophylaxis for Pregnant Patients with Mild-Risk Thrombophilia While Highlighting the Need for Future Studies.","authors":"Katherine Klein, Herney Andrés García-Perdomo, Cristhiam M Rojas Hernandez","doi":"10.1016/j.ajogmf.2026.102139","DOIUrl":"https://doi.org/10.1016/j.ajogmf.2026.102139","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102139"},"PeriodicalIF":3.6,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian A Burnett, Christian M Parobek, Westley Pollard, Cara Buskmiller, Roopali V Donepudi, Magdalena Sanz Cortes, Ahmed A Nassr, Michael A Belfort, Jessian L Munoz
{"title":"Clinical outcomes associated with abnormal middle cerebral artery Doppler velocities in fetal sacrococcygeal teratoma.","authors":"Brian A Burnett, Christian M Parobek, Westley Pollard, Cara Buskmiller, Roopali V Donepudi, Magdalena Sanz Cortes, Ahmed A Nassr, Michael A Belfort, Jessian L Munoz","doi":"10.1016/j.ajogmf.2026.102141","DOIUrl":"https://doi.org/10.1016/j.ajogmf.2026.102141","url":null,"abstract":"<p><strong>Background: </strong>Sacrococcygeal teratoma is a rare fetal tumor that may cause progressive hemodynamic compromise, fetal anemia, hydrops, and perinatal death. Although middle cerebral artery peak systolic velocity is widely used to assess fetal anemia, its prognostic value in pregnancies complicated by sacrococcygeal teratoma is not well established.</p><p><strong>Objective: </strong>To evaluate the association between abnormal fetal middle cerebral artery (MCA) Doppler velocities and neonatal outcomes in pregnancies complicated by fetal sacrococcygeal teratoma (SCT).</p><p><strong>Study design: </strong>We conducted a retrospective cohort study of prenatally diagnosed sacrococcygeal teratomas managed at a tertiary fetal center between January 2014 and January 2026. Cases were stratified by fetal middle cerebral artery (MCA) Doppler status (normal vs abnormal), with abnormal defined as a peak systolic velocity ≥ 1.5 multiples of the median (MoM). Prenatal sonographic findings, fetal interventions, and perinatal outcomes were compared between groups. The primary outcome was neonatal hemoglobin concentration at birth. Secondary outcomes included platelet count, neonatal mortality, Apgar score < 7 at 5 minutes, gestational age at delivery, age at postnatal surgical resection, and histopathologic findings from postnatal tumor specimens.</p><p><strong>Results: </strong>Among 36 fetuses with prenatally diagnosed SCT, 14 (39%) had abnormal MCA Doppler velocities. Neonates with abnormal MCA Dopplers had markedly lower hemoglobin concentrations at birth compared with those with normal MCA Dopplers (median 8.4 vs 16.9 g/dL, p < 0.01), accompanied by lower hematocrit (25% vs 51%, p < 0.01) and platelet counts (148 vs 220 × 10³/µL, p < 0.01), with increasing MCA peak systolic velocity associated with higher odds of neonatal anemia. Abnormal MCA Dopplers were also associated with higher neonatal mortality (40% vs 0%, p < 0.01), and, in the full cohort, with increased odds of perinatal death (OR 13.3, 95% CI 2.55-106), 5-minute Apgar < 7 (50% vs 10%, p = 0.03), and earlier gestational age at delivery (28 vs 36 weeks, p < 0.01). Final tumor histopathology differed between groups, with immature teratoma present in all liveborn neonates with abnormal MCA Dopplers compared with 45% in the normal MCA group (p < 0.01). Prenatal disease was also more severe in the abnormal MCA group, including higher tumor-to-fetal weight ratio (median 0.67 vs 0.15, p < 0.01), cardiomegaly (93% vs 27%, p < 0.01), hydrops (71% vs 9.1%, p < 0.01), and placentomegaly (50% vs 9.1%, p = 0.01).</p><p><strong>Conclusions: </strong>In this small retrospective cohort of fetuses with sacrococcygeal teratoma, abnormal MCA Doppler velocities were associated with severe neonatal anemia, thrombocytopenia, distinct tumor histopathology, and adverse neonatal outcomes. These findings suggest that MCA Doppler assessment may help identify higher-risk cases but require validation in larger","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102141"},"PeriodicalIF":3.6,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabrizio Zullo, Aaron W Roberts, Kristen Cagino, Elizabeth Wright-Jin, Yossi Bart, Hector Mendez-Figueroa, Mikko Tarvonen, Suneet P Chauhan, Daniele Di Mascio
{"title":"Hypoxic-ischemic encephalopathy and maternal adverse outcomes.","authors":"Fabrizio Zullo, Aaron W Roberts, Kristen Cagino, Elizabeth Wright-Jin, Yossi Bart, Hector Mendez-Figueroa, Mikko Tarvonen, Suneet P Chauhan, Daniele Di Mascio","doi":"10.1016/j.ajogmf.2026.102136","DOIUrl":"10.1016/j.ajogmf.2026.102136","url":null,"abstract":"<p><strong>Background: </strong>There is a paucity of publications on the composite maternal adverse outcomes (CMAO) among deliveries complicated with vs without neonatal hypoxic-ischemic encephalopathy (HIE).</p><p><strong>Objective: </strong>To compare the CMAO among deliveries complicated with vs without HIE.</p><p><strong>Study design: </strong>This is a secondary analysis of data from Assessment of Perinatal EXcellence (APEX), an observational study (from March 2008 to February 2011) conducted across 25 hospitals by the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. The inclusion criteria for our analysis were nonanomalous live-born singletons who were at least 35 weeks, who did not have scheduled cesarean delivery, and had information on whether the newborn had or did not have HIE. CMAO included any of the following: postpartum endometritis, obstetrical anal sphincter injury, blood transfusion, admission to intensive care unit (ICU), hysterectomy, or maternal death during hospitalization. Sensitivity analysis included CMAO among low- vs high-risk pregnancies. A low-risk pregnancy was defined as delivery at ≥37.0 weeks, without maternal comorbidity. Unadjusted and adjusted risk ratios (aRR) with 95% confidence intervals (CI) were estimated using Poisson regression with robust error variance, adjusting for variables significant in univariate analysis.</p><p><strong>Results: </strong>Among the 118,422 cohorts in the APEX database, 93,031 (78.6%) met the inclusion criteria, and among them, 871 (0.9%) had HIE. The overall rate of CMAO was 4.8% (4442/93,031). CMAO occurred in 8.7% of deliveries complicated by HIE compared with 4.8% of those without HIE (aRR 1.54, 95% CI 1.24, 1.91). The components of CMAO that differed significantly between the two groups included postpartum endometritis, blood transfusion, and admission to ICU. In this cohort, 80,942 pregnancies (87.1%) were classified as low-risk, and 691 of the 871 cases of hypoxic-ischemic encephalopathy (79.3%) occurred in this group. In low-risk pregnancies, CMAO occurred in 7.8% of deliveries complicated by HIE vs 4.5% of those without HIE (aRR 1.51; 95% CI 1.17, 1.96). Similarly, among high-risk pregnancies, CMAO occurred in 12.2% vs 6.2%, respectively (aRR 1.93; 95% CI 1.30,2.88).</p><p><strong>Conclusion: </strong>The CMAO occurred in ∼1 out of 10 deliveries complicated by HIE, and it was 1.5-fold higher rate than deliveries without HIE. These findings suggest that neonatal HIE and maternal morbidity frequently coexist, including among pregnancies otherwise classified as low risk.</p>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102136"},"PeriodicalIF":3.6,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannaneh Mirmozaffari, Matthew Fuller, Madison Calvert, Kim Boggess, Jaye Boissiere, Maya Patel, Sally Kuehn, Brooke Schroeder, Jerome Federspiel, Johanna Quist-Nelson, Marie-Louise Meng
{"title":"Association between diagnostic criteria of preeclampsia with severe features and adverse perinatal outcomes.","authors":"Hannaneh Mirmozaffari, Matthew Fuller, Madison Calvert, Kim Boggess, Jaye Boissiere, Maya Patel, Sally Kuehn, Brooke Schroeder, Jerome Federspiel, Johanna Quist-Nelson, Marie-Louise Meng","doi":"10.1016/j.ajogmf.2026.102135","DOIUrl":"10.1016/j.ajogmf.2026.102135","url":null,"abstract":"<p><strong>Background: </strong>Preeclampsia with severe features (PEC-SF) is a hypertensive disorder of pregnancy associated with significant maternal and perinatal morbidity. It is defined by heterogenous criteria, including severe hypertension and signs of end-organ dysfunction. Whether individual criteria confer differential risk for adverse perinatal outcomes remains unclear. This gap limits clinicians' ability to risk stratify patients, guide management decisions, and provide individualized counseling regarding prognosis.</p><p><strong>Objective: </strong>To estimate the association between individual diagnostic criteria in preeclampsia with severe features and adverse perinatal outcomes.</p><p><strong>Study design: </strong>This is a retrospective cohort study of patients with antepartum PEC-SF who delivered at two academic medical centers from 2016-2017. Exposures included the number and type of severe criteria present at diagnosis. Our primary outcome was a composite of placental abruption, preterm birth < 34 weeks, a small for gestational age infant, or fetal demise. Secondary outcomes included preterm birth < 37 weeks, delivery type, or < 7 days of latency from diagnosis to delivery among those diagnosed at < 33 weeks. A multivariate logistic regression model adjusted for maternal age, race, and pre-existing medical conditions estimated the adjusted odds ratios (aOR) and 95% confidence interval (CI) for the primary outcome.</p><p><strong>Results: </strong>There were 704 patients with PEC-SF. Of these, 608 (86.4%) had severe hypertension, 246 (34.9%) reported neurological symptoms, and 332 (47.2%) presented with ≥ 2 severe criteria. Of 704, 371 (52.7%) had a single criterion, most often severe hypertension (81.1%). The primary outcome was associated with severe hypertension (aOR: 1.36, 95% CI: 1.22, 1.52), thrombocytopenia (aOR 1.28, 95% CI 1.13, 1.45), progressive renal insufficiency (aOR 1.16, 95% CI 1.03, 1.31), and impaired liver function (aOR 1.15, 95% CI 1.04, 1.28). Unplanned cesarean delivery was associated with severe hypertension (aOR:1.42, 95% CI: 1.02, 1.98) and impaired liver function (aOR: 1.13, 95% CI: 1.02, 1.25). The odds of the primary composite outcome increased with each additional criterion; among patients with severe hypertension, the association between the primary outcome was significant among those with two to three additional severe features (aOR 1.47, 95% CI 1.30, 1.67).</p><p><strong>Conclusion: </strong>Our findings demonstrate that not all severe features carry equal odds of adverse pregnancy outcome and highlight the importance of considering both the type and number of criteria when risk stratifying patients and guiding clinical management.</p>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102135"},"PeriodicalIF":3.6,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valerie Stålberg, Marie Bladh, Barbro Krevers, Louise Möller, Nina Lindell, Ann Josefsson, Caroline Lilliecreutz
{"title":"Maternal and neonatal outcomes in a reduced visit antenatal care program for women at low risk for complications.","authors":"Valerie Stålberg, Marie Bladh, Barbro Krevers, Louise Möller, Nina Lindell, Ann Josefsson, Caroline Lilliecreutz","doi":"10.1016/j.ajogmf.2026.102134","DOIUrl":"10.1016/j.ajogmf.2026.102134","url":null,"abstract":"<p><strong>Background: </strong>Public healthcare operates with constrained resources, creating a need to reallocate capacity toward the growing population of pregnant women at high risk for complications. Therefore, a modified antenatal care program with a reduced number of in-person visits supplemented with telemedicine consultations was introduced for low-risk women in Southeast Sweden.</p><p><strong>Objective: </strong>To evaluate whether a modified antenatal care program is noninferior to a standard antenatal care program regarding maternal and neonatal outcomes.</p><p><strong>Study design: </strong>A modified antenatal care program was evaluated at five antenatal care centers through a step-wedge cluster randomization design. The evaluation period extended from October 2020 to September 2024. Women at low-risk for complications were identified at gw 11 to 15 through comprehensive risk assessment, including risk of developing preterm preeclampsia using the Fetal-Medicine-Foundation method. The standard antenatal care program included eight in-person visits to a midwife and the modified antenatal care program comprised four in-person visits plus two telemedicine consultations. All women received two routine ultrasounds and standardized lifestyle counselling. The primary outcome was a composite of maternal outcomes (preterm birth, pregnancy-induced hypertension, preeclampsia, eclampsia and anemia). Secondary outcome was a composite of neonatal outcomes (Apgar <7 at 5 min, being small for gestational age or large for gestational age, and intrauterine fetal demise). Analyses followed the intention-to-treat principle, using logistic regression models adjusted for parity, education, and region of origin.</p><p><strong>Results: </strong>The study population included 5374 women: 2768 in the standard antenatal care program and 2606 in the modified antenatal care program. The median number of in-person visits was 8 vs 4 (P<.001). No significant differences were found for the maternal composite (10.9% vs 10.5%, P=.640) or neonatal composite (6.8% vs 6.8%, P=.472) between the modified and standardized programs. The modified antenatal care program was associated with lower induction of labor rates (15.6% vs 19.0%, P<.001) and higher rates of spontaneous vaginal births (87.9% vs 84.8%, P=.001).</p><p><strong>Conclusion: </strong>The modified antenatal care program with fewer in-person visits supplemented by telemedicine did not differ from standard care with respect to maternal and neonatal safety among women at low-risk for complications. Moreover, the modified antenatal care program was associated with fewer obstetric interventions and represented a safe and efficient alternative in a high-welfare healthcare setting.</p>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102134"},"PeriodicalIF":3.6,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pericerclage tocolytics, antibiotics, or their combination and risk of preterm birth: a systematic review and meta-analysis.","authors":"Ilaria Paladino, Carly Friedman, Teresa Cobo, Vincenzo Berghella","doi":"10.1016/j.ajogmf.2026.102140","DOIUrl":"https://doi.org/10.1016/j.ajogmf.2026.102140","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether adjunctive pericerclage therapy with tocolytics, antibiotics, or combination therapy is associated with reduced preterm birth (PTB) and improved maternal and neonatal outcomes according to therapy type and cerclage indication.</p><p><strong>Data sources: </strong>A systematic search of PubMed, Scopus, MEDLINE, and CENTRAL was conducted from database inception through March 4, 2026.</p><p><strong>Study eligibility criteria: </strong>Randomized and nonrandomized controlled studies evaluating singleton or twin pregnancies undergoing transvaginal cervical cerclage were included. Eligible studies compared perioperative adjunctive therapy, including tocolytics, antibiotics, or both, administered within 24 hours before, during, or within 48 hours after cerclage placement, with cerclage without adjunctive therapy. Studies involving transabdominal cerclage, higher-order multifetal gestations, or non-extractable cerclage-specific data were excluded.</p><p><strong>Study appraisal and synthesis methods: </strong>Risk of bias was assessed using RoB-2 and ROBINS-I tools. Random-effects meta-analyses with restricted maximum likelihood estimation (REML) were performed to calculate pooled odds ratios (OR) and mean differences with 95% confidence intervals (CI). The primary analysis compared any adjunctive pericerclage therapy vs no adjunctive therapy. Prespecified subgroup analyses were conducted according to adjunctive therapy type (tocolytics and antibiotics alone or in combination) and cerclage indication, including ultrasound-indicated cerclage (UIC) and physical examination-indicated cerclage (PEIC). The primary outcome was PTB <37 weeks of gestation.</p><p><strong>Results: </strong>Seven studies met inclusion criteria, and 6 were included in the quantitative analysis, involving 878 patients. Adjunctive pericerclage therapy was not associated with reduced PTB <37 weeks compared with cerclage alone (OR 0.92; 95% CI 0.65-1.31). No significant differences were observed for PTB <32, <28, or <24 weeks, gestational age at delivery, gestational latency, chorioamnionitis, preterm premature rupture of membranes, birthweight, or neonatal survival. Similarly, subgroup analyses according to therapy type, including tocolytics alone, antibiotics alone, and combination therapy, similarly showed no significant effect. In the UIC subgroup, no association between adjunctive therapy and PTB <37 weeks was observed (OR, 1.14; 95% CI, 0.71-1.85). In the PEIC subgroup, adjunctive therapy was associated with a nonsignificant trend toward reduced PTB <37 weeks (OR, 0.72; 95% CI, 0.43-1.21), PTB <28 weeks (OR, 0.70; 95% CI, 0.37-1.34), and PTB <24 weeks (OR, 0.44; 95% CI, 0.18-1.08), as well a longer (by >1 week) latency.</p><p><strong>Conclusions: </strong>Adjunctive pericerclage therapy with tocolysis and/or antibiotics was not associated with reduced PTB or improved maternal and neonatal outcomes. Indication-specific analyses did ","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102140"},"PeriodicalIF":3.6,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to editor regarding \"Ultrasound-first, anatomy-based algorithm to tailor the extent of hysterectomy in placenta accreta spectrum\".","authors":"Yalda Afshar, Helena C Bartels, Eric Jauniaux","doi":"10.1016/j.ajogmf.2026.102126","DOIUrl":"10.1016/j.ajogmf.2026.102126","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"102126"},"PeriodicalIF":3.6,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expression of concern \"Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials\".","authors":"","doi":"10.1016/j.ajogmf.2026.102065","DOIUrl":"https://doi.org/10.1016/j.ajogmf.2026.102065","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 9","pages":"102065"},"PeriodicalIF":3.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Fay MD (Associate Professor of Obstetrics and Gynecology), Stephanie Fonda (Vice President, Research Initiatives), Nicole Ehrhardt MD (Assistant Professor of Medicine, Medical Director)
{"title":"Letter to Editor regarding “A randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) for self-management of gestational diabetes”","authors":"Emily Fay MD (Associate Professor of Obstetrics and Gynecology), Stephanie Fonda (Vice President, Research Initiatives), Nicole Ehrhardt MD (Assistant Professor of Medicine, Medical Director)","doi":"10.1016/j.ajogmf.2026.102069","DOIUrl":"10.1016/j.ajogmf.2026.102069","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"8 9","pages":"Article 102069"},"PeriodicalIF":3.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}