American Journal of Obstetrics & Gynecology Mfm最新文献

{"title":"Breast stimulation vs low dose oxytocin for labor augmentation in women with a previous cesarean delivery, a randomized controlled trial","authors":"Raneen Abu Shqara MD , Gabriela Goldinfeld MD , Tikva Assulyn MD , Inshirah Sgayer MD , Nadir Ganem MD , Lior Lowenstein MD , Maya Frank Wolf MD","doi":"10.1016/j.ajogmf.2025.101658","DOIUrl":"10.1016/j.ajogmf.2025.101658","url":null,"abstract":"<div><h3>Background</h3><div>Oxytocin and breast stimulation are methods used for labor augmentation in women with a previous cesarean delivery (CD). Compared to spontaneous labor, labor augmentation has been shown to increase the risk of uterine rupture in women with a previous CD. The optimal method of labor augmentation for women with a prior CD has not been established.</div></div><div><h3>Objective</h3><div>In a cohort of patients with one previous CD, we aimed to compare maternal and neonatal outcomes according to the method of labor augmentation; breast stimulation or intravenous oxytocin.</div></div><div><h3>Study Design</h3><div>This randomized controlled trial (RCT) was conducted at a single, tertiary, university-affiliated hospital. The participants had one previous CD and a cervical dilatation of 2 to 6 cm, had inadequate uterine contractions, defined as less than 3 per 10 minutes, and were candidates for labor augmentation. They were randomized for augmentation by breast stimulation using a breast pump, or by intravenous low-dose oxytocin starting at 0.5 to 2 milliunits/min and increasing incrementally by 1 to 2 milliunits/min every 15 to 40 minutes. An intrauterine pressure catheter was inserted. Both augmentation treatments were continued for a maximum of 12 hours. If active labor did not occur within 12 hours, the intervention was deemed a failure. An intention-to-treat analysis was performed. The co-primary outcomes were the time from augmentation to delivery, and uterine contraction intensity as measured by Montevideo units (MVU). Secondary outcomes included intervention failure, meconium-stained amniotic fluid, vaginal delivery after cesarean section, uterine rupture, infectious outcomes, postpartum hemorrhage, and maternal hospitalization length. The neonatal outcomes included: Apgar score at 5 minutes, umbilical cord pH<7.1, neonatal intensive care unit admission, asphyxia, and perinatal death.</div></div><div><h3>Results</h3><div>The breast stimulation and the intravenous oxytocin groups included 33 and 34 patients, respectively. The participants’ demographic and obstetric characteristics were similar. The median time from augmentation to delivery was longer in the breast stimulation than the oxytocin group: 10.9 hours (total range 1.5–63.2) vs 5.1 hours (0.8–30), <em>P</em><.001. The median (range) contraction intensity as measured by MVU was similar between the groups in the first stage of labor, 125 (70–270) vs 180 (80–280), <em>P</em>=.110; and in the second stage of labor, 145 (30–280), vs 175 (50–290), <em>P</em>=.164. The tachysystole rate was lower, with statistical significance, in the breast stimulation than the oxytocin group, 6% vs 27%, <em>P</em>=.044; while the rates of tachysystole-associated nonreassuring fetal heart rates did not differ significantly, 6% vs 21%, <em>P</em>=.427. Similar proportions of patients delivered within 24 hours of intervention. Uterine rupture occurred in two patients in the ox","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 5","pages":"Article 101658"},"PeriodicalIF":3.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor regarding \"Does combining warm perineal compresses with perineal massage during the second stage of labor reduce perineal trauma? A randomized controlled trial\": reevaluating perineal protection: the impact of warm compresses and perineal massage during the second stage of labor.","authors":"Ruijuan Chen, Jingni Zhao, Binglin Li","doi":"10.1016/j.ajogmf.2025.101662","DOIUrl":"10.1016/j.ajogmf.2025.101662","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"101662"},"PeriodicalIF":3.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Warm compresses during labor: addressing clinical considerations.","authors":"Raneen Abu Shqara, Lior Lowenstein, Susana Mustafa Mikhail","doi":"10.1016/j.ajogmf.2025.101661","DOIUrl":"10.1016/j.ajogmf.2025.101661","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":" ","pages":"101661"},"PeriodicalIF":3.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“The role of pravastatin in preventing preeclampsia in high-risk pregnant women: a meta-analysis with trial sequential analysis”","authors":"Muhammad Ilham Aldika Akbar MD, PhD, Gustaaf Dekker MD, PhD","doi":"10.1016/j.ajogmf.2024.101585","DOIUrl":"10.1016/j.ajogmf.2024.101585","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 3","pages":"Article 101585"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to letter to the editor regarding “The preeclampsia and hypertension target treatment study: a multicenter prospective study to evaluate the effectiveness of the antihypertensive therapy based on maternal hemodynamic findings”","authors":"Elvira di Pasquo MD, Tullio Ghi MD, PhD","doi":"10.1016/j.ajogmf.2025.101601","DOIUrl":"10.1016/j.ajogmf.2025.101601","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 3","pages":"Article 101601"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonsevere hypertensive disorders of pregnancy and oral antihypertensive medications: an argument in favor of use","authors":"Lorena Carolina Martinez-King MD, MAS,&nbsp;Leah M Savitsky MD,&nbsp;Sherill Rose MD,&nbsp;Catherine Albright MD, MS","doi":"10.1016/j.ajogmf.2024.101561","DOIUrl":"10.1016/j.ajogmf.2024.101561","url":null,"abstract":"<div><div>Hypertensive disorders of pregnancy are a common complication of pregnancy and a major contributor to both immediate and long-term morbidity and mortality. Recent data support the treatment of chronic hypertension during pregnancy to a blood pressure goal of &lt;140/90 mmHg. Treatment of severe range blood pressures (<span><math><mo>≥</mo></math></span>160/110 mmHg) in the setting of gestational hypertension is recommended to prevent severe morbidity and mortality; however, there remains clinical equipoise regarding treatment of gestational hypertension with blood pressures <span><math><mo>≥</mo></math></span>140/90 but &lt;160/110. While there is limited data to support the treatment of gestational hypertension, we believe that treatment of gestational hypertension to a blood pressure of &lt;140/90, similar to the recommendations for chronic hypertension, will lead to a reduction in severe maternal and neonatal morbidity and mortality related to hypertensive disorders of pregnancy. In this expert review, we summarize the available data regarding the treatment of gestational hypertension and offer recommendations for the treatment of gestational hypertension based on our clinical experience.</div></div>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 1","pages":"Article 101561"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the letter regarding “systematic review on music interventions during pregnancy in favor of the well-being of mothers and eventually their offspring”","authors":"Johanna Maul MD,&nbsp;Birgit Arabin MD, PhD","doi":"10.1016/j.ajogmf.2024.101588","DOIUrl":"10.1016/j.ajogmf.2024.101588","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 3","pages":"Article 101588"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of single vs double-blind peer review: a difference-in-difference analysis","authors":"Rula Atwani MD,&nbsp;Carole Barake MD,&nbsp;Misooja Lee MD,&nbsp;George Saade MD,&nbsp;Hugh Taylor MD,&nbsp;Jim C. Huang PhD,&nbsp;Tetsuya Kawakita MD, MS","doi":"10.1016/j.ajogmf.2024.101582","DOIUrl":"10.1016/j.ajogmf.2024.101582","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 3","pages":"Article 101582"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaginal progesterone for prevention of preterm birth in women with a history of preterm birth regardless of cervical length: an argument for use","authors":"Charlette E. Williams MD,&nbsp;Rupsa C. Boelig MD, MS","doi":"10.1016/j.ajogmf.2024.101565","DOIUrl":"10.1016/j.ajogmf.2024.101565","url":null,"abstract":"<div><div>It is well understood that preterm birth accounts for a substantial amount of poor neonatal outcomes. In 2022, preterm birth affected about 1 of every 10 infants born in the United States with complications ranging from mild respiratory distress syndrome to neonatal death. The complexity of the treatment is secondary to the fact that preterm birth is a multifactorial syndrome with intricate sociocultural factors that influence our racially disproportionate poor outcomes. One of the key risk factors for preterm birth is a history of spontaneous preterm birth. Currently, there are conflicting recommendations regarding the use of vaginal progesterone prophylactically for the prevention of recurrent preterm birth. As described in Practice Bulletin number 234 of the American College of Obstetricians and Gynecologists, the current recommendation is that patients with a singleton pregnancy and previous spontaneous preterm birth should be assessed with serial endovaginal ultrasound cervical length measurements to determine eligibility for vaginal progesterone. In contrast, the Society for Maternal-Fetal Medicine suggests the use of prophylactic vaginal progesterone with patient-centered counseling and shared decision-making. We aimed to present the rationale for the use of prophylactic vaginal progesterone in patients with singleton gestations and a history of spontaneous preterm birth.</div></div>","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 1","pages":"Article 101565"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum care receipt among parents of preterm infants admitted to the neonatal intensive care unit","authors":"Kristan Scott MD,&nbsp;Rachel F. Ledyard MPH,&nbsp;Niesha Darden,&nbsp;Celeste Durnwald MD,&nbsp;Sara C. Handley MD, MSCE,&nbsp;Timothy D. Nelin MD,&nbsp;Maggie Power CNM, MSN,&nbsp;Taneisha R. Sinclair MD,&nbsp;Heather H. Burris MD, MPH","doi":"10.1016/j.ajogmf.2025.101659","DOIUrl":"10.1016/j.ajogmf.2025.101659","url":null,"abstract":"","PeriodicalId":36186,"journal":{"name":"American Journal of Obstetrics & Gynecology Mfm","volume":"7 5","pages":"Article 101659"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}