Structural Heart最新文献

{"title":"Re-Evaluation of Valvulo-Arterial Impedance in Aortic Stenosis: Insights From 3-Element Windkessel Analysis","authors":"Sara Hungerford MD, PhD , Ning Song MD , David Muller MD , Audrey Adji MB, MBiomedE, PhD","doi":"10.1016/j.shj.2024.100374","DOIUrl":"10.1016/j.shj.2024.100374","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100374"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Replacement Sizing: Getting It Right","authors":"Ori Ben-Yehuda MD, Ryan R. Reeves MD","doi":"10.1016/j.shj.2024.100302","DOIUrl":"10.1016/j.shj.2024.100302","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100302"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Essential Aortic Valve-in-Valve Transcatheter Aortic Valve Replacement Update: Procedural Strategies and Current Clinical Results","authors":"Matheus Simonato MD ,&nbsp;José Honório Palma MD ,&nbsp;Zaid Alirhayim MD ,&nbsp;Raviteja Guddeti MD ,&nbsp;Tsuyoshi Kaneko MD ,&nbsp;Santiago Garcia MD","doi":"10.1016/j.shj.2024.100318","DOIUrl":"10.1016/j.shj.2024.100318","url":null,"abstract":"<div><div>Valve-in-valve transcatheter aortic valve replacement is an established alternative to conventional surgical reoperation for failed aortic bioprosthetic valves. The technique has undergone significant refinements in recent years, aiming to tackle pain points of the procedure such as subpar hemodynamics and coronary obstruction. In this state-of-the-art review, we aim to discuss these refinements, including novel surgical valves, transcatheter heart valve positioning, bioprosthetic valve fracture, and prevention of coronary obstruction, among others. We also summarize key updates on clinical trial data and contemporary outcomes of valve-in-valve transcatheter aortic valve replacement.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100318"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Staging of Cardiac Damage for Aortic Stenosis: A Review","authors":"Wally Omar MD ,&nbsp;Philippe Généreux MD","doi":"10.1016/j.shj.2024.100370","DOIUrl":"10.1016/j.shj.2024.100370","url":null,"abstract":"<div><div>The advent and success of transcatheter aortic valve replacement (TAVR) for the treatment of severe, symptomatic aortic stenosis (AS) has sparked a renewed interest in the disease process associated with the valve disorder. While it is evident that untreated AS is fatal, the progressive and cumulative effects of AS on the heart have only recently been studied in a widespread fashion, after the initial pivotal TAVR trials in the United States. From these data, a novel staging system has been developed to characterize the extent of cardiac damage caused by AS. This staging system facilitates risk stratification of patients with AS using echocardiographic data and measurements to derive an assessment of morbidity and mortality. After being successfully validated using outcomes from several TAVR trials, the model has now been extrapolated to patients with moderate AS and other cardiac valve disorders as well. In this review, we explore the origins of the cardiac damage staging system, its validation, and uses in various cardiac conditions.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100370"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aims & Scope","authors":"","doi":"10.1016/S2474-8706(25)00024-7","DOIUrl":"10.1016/S2474-8706(25)00024-7","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100432"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prognostic Relevance of a New Bundle Branch Block After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis","authors":"Karan Rao MD, BMed, MPH ,&nbsp;Mohammed Ahmed BEng (Mech) ,&nbsp;Daniel Brieger MBBS ,&nbsp;Alexandra Baer BSN, MSHM ,&nbsp;Peter Hansen MBBS, PhD ,&nbsp;Ravinay Bhindi MBBS, PhD","doi":"10.1016/j.shj.2024.100392","DOIUrl":"10.1016/j.shj.2024.100392","url":null,"abstract":"<div><h3>Background</h3><div>Interference with the cardiac conduction system is common after transcatheter aortic valve implantation (TAVI), manifesting as atrioventricular block, or more commonly, new-onset persistent left bundle branch block (NOP-LBBB). Bundle branch block results in ventricular dyssynchrony and reduced cardiac output and may be associated with a poorer prognosis. This systematic review and meta-analysis evaluates the prognostic impact of a left or right bundle branch block after TAVI.</div></div><div><h3>Methods</h3><div>A systematic review was performed of the following online databases: PubMed, Medline, Scopus, and Web of Science, including English language studies from 2014 to 2024. Two separate searches for conducted for NOP-LBBB and new-onset persistent right bundle branch block (NOP-RBBB). The Newcastle-Ottawa Scale was used to evaluate risk of bias.</div></div><div><h3>Results</h3><div>Twenty-three studies totaling 18875 patients were included for NOP-LBBB, whilst 5 studies with a total of 3525 patients were included for NOP-RBBB. NOP-LBBB was associated with higher all-cause mortality at 1 year (risk ratio [RR] 1.41 [95% CI 1.12-1.78], I² = 49%, <em>p</em> &lt; 0.01), cardiovascular mortality (RR 1.34 [95% CI 1.02-1.75], I² = 60%, <em>p</em> = 0.02), heart failure-related rehospitalization (RR 1.56 [95% CI 1.31-1.84], I² = 47%, <em>p</em> &lt; 0.01), and permanent pacemaker implantation at 1 year (RR 3.05 [95% CI 2.39-3.89], I² = 14%, <em>p</em> &lt; 0.01). NOP-RBBB was not associated with higher all-cause mortality at 1 year (RR 1.74 [95% CI 0.88-3.46], I² = 93%, <em>p</em> = 0.11), however increased the risk of pacemaker implantation at 1 year (RR 4.68 [95% CI 3.60-6.08], I² = 67%, <em>p</em> &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>NOP-LBBB is associated with higher mortality and heart failure rehospitalization after TAVI, whilst both NOP-LBBB and NOP-RBBB increase the risk of permanent pacemaker implantation at 1 year after TAVI.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100392"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal Trends in Utilization of Structural Heart Interventions Among Patients With Amyloidosis","authors":"Shashank Shekhar MD ,&nbsp;Akiva Rosenzveig MD ,&nbsp;Osamah Badwan MD,&nbsp;Ankit Agrawal MD,&nbsp;Amar Krishnaswamy MD,&nbsp;Grant Reed MD, MSc,&nbsp;Rishi Puri MD, PhD,&nbsp;Mazen Hanna MD,&nbsp;Samir Kapadia MD","doi":"10.1016/j.shj.2024.100397","DOIUrl":"10.1016/j.shj.2024.100397","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100397"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of 30% or More Volume Reduction Achieved by Surgical Ventricular Reconstruction for Ischemic Cardiomyopathy: A Systematic Review","authors":"Harun Osmani MSc ,&nbsp;Paulien Christine Hoefsmit MD ,&nbsp;Romy R.M.J.J. Hegeman MD ,&nbsp;George Louis Burchell MSc ,&nbsp;Jolanda Kluin MD, PhD ,&nbsp;Patrick Klein MD, PhD ,&nbsp;Reinier Zandbergen MD, PhD","doi":"10.1016/j.shj.2024.100390","DOIUrl":"10.1016/j.shj.2024.100390","url":null,"abstract":"<div><h3>Background</h3><div>Ischemic cardiomyopathy, commonly attributable to coronary artery disease, leads to ventricular remodeling. Surgical ventricular reconstruction (SVR) aims to reverse this by restoring cardiac morphology. This review evaluates SVR's influence on ventricular volume reduction, comparing &lt;30% to &gt;30% reduction effects on left ventricular ejection fraction (LVEF) and patient outcomes.</div></div><div><h3>Methods</h3><div>A systematic search following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines was performed in PubMed, Embase, Web of Science, and the Cochrane Collaboration. Data extracted included left ventricular end systolic volume, LVEF, New York Heart Association classification, mitral regurgitation grade, and mortality rates.</div></div><div><h3>Results</h3><div>Of the 37 articles included, 29 reported a mean volume reduction of &gt;30%, while 8 reported a reduction &lt;30%. A total of 4975 participants were included across all studies. Mean volume reduction was 43% in group 1 (&gt;30%) and 28% in group 2 (&lt;30%). The mean relative increase in LVEF for group 1 was 38%, which was larger compared to group 2 with 30%. Additionally, mean reduction in New York Heart Association class was 1.5 in group 1 and 1.2 in group 2. There was no difference in mitral regurgitation grade reduction between the 2 groups. Postoperative mortality within 30 days was 5.8% in group 1 vs. 5.2% in group 2.</div></div><div><h3>Conclusions</h3><div>Both volume reduction groups showed improved LVEF and outcomes post-SVR, indicating the efficacy of SVR. The majority of studies achieved a volume reduction exceeding 30%, surpassing the 19% reported in the Surgical Treatment for Ischemic Heart Failure trial. Further meta-analysis can determine optimal volume reduction for enhanced cardiac function and outcomes.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100390"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Therapy of Valvular Heart Disease?","authors":"Anthony DeMaria MD","doi":"10.1016/j.shj.2025.100429","DOIUrl":"10.1016/j.shj.2025.100429","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 3","pages":"Article 100429"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Ultrasound-Based Therapies in Cardiovascular Diseases","authors":"Amit Bansal MBBS, PGDip, MPhil, GCert ,&nbsp;Bernard Bulwer MD ,&nbsp;Ricarda von Krüchten Priv.-Doz., Dr. M. ,&nbsp;Jagkirat Singh MD ,&nbsp;Rajan Rehan MBBS, MPH ,&nbsp;Ata Doost MD, MPhil","doi":"10.1016/j.shj.2024.100349","DOIUrl":"10.1016/j.shj.2024.100349","url":null,"abstract":"<div><div>Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality globally, placing an immense burden on health care costs worldwide. The emergence of therapeutic ultrasound-based therapies in the CVD management represents a promising innovative strategy beyond current established approaches. This paper explores three distinct modalities of ultrasound-based therapies—high-intensity focused ultrasound, extracorporeal shock wave therapy, and low-intensity pulsed ultrasound—each characterized by unique acoustic parameters and mechanisms of action tailored to specific therapeutic outcomes. High-intensity focused ultrasound was shown to be beneficial as an adjunct in the treatment of myocardial infarction and arrhythmias. It has also been investigated for the <em>in vivo</em> treatment of resistant hypertension, symptomatic aortic valve stenosis, arterial stenosis, tumors, hypertrophic cardiomyopathy, and external cardiac pacing. Extracorporeal shock wave therapy was shown to be beneficial in the treatment of chronic refractory angina pectoris, while low-intensity pulsed ultrasound was shown to be beneficial in dissolving blood clots and improving blood flow in the treatment of acute pulmonary embolism, despite its association with an increased risk of bleeding. Ultrasound-based therapies are, therefore, a potential adjunct and comparatively safe adjuncts for managing challenging CVD cases. Further investigations are essential to validate their long-term effectiveness and safety, particularly for high-risk individuals susceptible to postprocedural complications.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 2","pages":"Article 100349"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141844108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}