Structural HeartPub Date : 2025-06-01DOI: 10.1016/j.shj.2025.100514
Mrinal Krishna , Chidubem Ezenna , Meghna Joseph , Mohammad Mouslmani , Armin Nouri , Raiza Rossi , Kuan Yu Chi , Luis Sanchez , Michael Nanna , Andrew Goldsweig
{"title":"71948 | Transradial vs Transfemoral Secondary Access for Transfemoral TAVR","authors":"Mrinal Krishna , Chidubem Ezenna , Meghna Joseph , Mohammad Mouslmani , Armin Nouri , Raiza Rossi , Kuan Yu Chi , Luis Sanchez , Michael Nanna , Andrew Goldsweig","doi":"10.1016/j.shj.2025.100514","DOIUrl":"10.1016/j.shj.2025.100514","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 ","pages":"Article 100514"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Structural HeartPub Date : 2025-06-01DOI: 10.1016/j.shj.2024.100408
Collin J. Brooks MD , Neal Duggal MD , Milan Seth MS , Megan S. Joseph MD , Devraj Sukul MD, MSc , Stan J. Chetcuti MD , Gorav Ailawadi MD , Himanshu Patel MD , P. Michael Grossman MD , Raed Alnajjar MD , Andrew W. Harris MD
{"title":"Quality of Life After Mitral Transcatheter Edge-to-Edge Repair According to Baseline Tricuspid Regurgitation","authors":"Collin J. Brooks MD , Neal Duggal MD , Milan Seth MS , Megan S. Joseph MD , Devraj Sukul MD, MSc , Stan J. Chetcuti MD , Gorav Ailawadi MD , Himanshu Patel MD , P. Michael Grossman MD , Raed Alnajjar MD , Andrew W. Harris MD","doi":"10.1016/j.shj.2024.100408","DOIUrl":"10.1016/j.shj.2024.100408","url":null,"abstract":"<div><h3>Background</h3><div>There is a high prevalence of significant tricuspid regurgitation (TR) in patients undergoing mitral transcatheter edge-to-edge repair (M-TEER). Significant TR is associated with poor prognosis and affects decision-making between M-TEER and concomitant mitral and tricuspid valve surgery. Improved quality of life (QoL) is an important metric for patients.</div></div><div><h3>Methods</h3><div>We analyzed data from 1838 patients undergoing M-TEER included in a multicenter statewide registry from 2015 to 2023. QoL was assessed using baseline and 30-day Kansas City Cardiomyopathy Questionnaire (KCCQ) scores. Patients were classified as no/mild TR or moderate/severe TR, and changes in KCCQ scores were compared. The primary outcome was an adjusted analysis consisting of survival to 30 days with a ≥15-point improvement in KCCQ score.</div></div><div><h3>Results</h3><div>Complete endpoint data were available for 1421 patients (77.3%). On average, patients undergoing M-TEER experienced large improvements in QoL, regardless of baseline TR group. Thirty-day mortality for patients with moderate/severe TR was higher than for those with no/mild TR (42 [4.1%] vs. 16 [2.0%], respectively, <em>p</em> = 0.018). The majority of patients survived to 30 days with ΔKCCQ ≥15 (63.8% for no/mild TR vs. 59.6% for moderate/severe TR, <em>p</em> = 0.120). Patients with moderate/severe TR exhibited no difference in the primary adjusted outcome (adjusted odds ratio: 0.851, <em>p</em> = 0.177).</div></div><div><h3>Conclusions</h3><div>The majority of patients experience a large improvement in QoL after M-TEER, regardless of baseline TR severity. Further research should explore a staged approach of M-TEER followed by tricuspid valve intervention as needed compared to concomitant mitral/tricuspid valve surgery.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 6","pages":"Article 100408"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Structural HeartPub Date : 2025-06-01DOI: 10.1016/j.shj.2025.100570
Omar Chehab , Robert Smith , Ali Vazir , Tom Cahill , Karine Grigoryan , Jim Newton , Ee Ling Heng , Russell Franks , Alison Duncan , Sam Dawkins , Bernard Prendergast , Ronak Rajani , Simon Redwood , Tiffany Patterson
{"title":"71545 | Biventricular Pressure-Volume Loops During Mitral Transcatheter Edge-to-Edge Repair: The Relationship Between Physiology and Health Status Outcomes","authors":"Omar Chehab , Robert Smith , Ali Vazir , Tom Cahill , Karine Grigoryan , Jim Newton , Ee Ling Heng , Russell Franks , Alison Duncan , Sam Dawkins , Bernard Prendergast , Ronak Rajani , Simon Redwood , Tiffany Patterson","doi":"10.1016/j.shj.2025.100570","DOIUrl":"10.1016/j.shj.2025.100570","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 ","pages":"Article 100570"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}