Structural Heart最新文献

{"title":"Outcomes of Left Atrial Appendage Occlusion in Patients With Cardiac Amyloidosis","authors":"Sonia Kshatri MD , David Lewandowski MD , Jake Luo PhD , Mohammad Assadi Shalmani , Marcie Berger MD , Jalaj Garg MBBS , Divyanshu Mohananey MBBS, MSc","doi":"10.1016/j.shj.2026.100795","DOIUrl":"10.1016/j.shj.2026.100795","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 4","pages":"Article 100795"},"PeriodicalIF":2.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146174316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bench Testing of a New, Semirigid, Saddle-Shaped, Complete Mitral Annuloplasty Ring Designed to Circularize During Transcatheter Mitral Valve-in-Ring Procedures","authors":"Keith B. Allen MD , Daniel J. Romary MD, MS , Elizabeth A. Grier MD , Chetan P. Huded MD , Duc T. Pham MD , Douglas R. Johnston MD , Panos N. Vardas MD , John R. Davis MD , Adnan K. Chhatriwalla MD","doi":"10.1016/j.shj.2025.100791","DOIUrl":"10.1016/j.shj.2025.100791","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 4","pages":"Article 100791"},"PeriodicalIF":2.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aims & Scope","authors":"","doi":"10.1016/S2474-8706(26)00048-5","DOIUrl":"10.1016/S2474-8706(26)00048-5","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 4","pages":"Article 100839"},"PeriodicalIF":2.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147649811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ischemic vs. Nonischemic Cardiomyopathy in TAVR for Moderate Aortic Stenosis: A TAVR UNLOAD Sub Analysis","authors":"Philipp von Stein MD , Henning Guthoff MD , Björn Redfors MD, PhD , Julia B. Thompson MS , Ernest Spitzer MD , Philippe Pibarot DVM, PhD , Jeroen J. Bax MD, PhD , Jan G.P. Tijssen PhD , Michael L. Chuang MD , Yukari Kobayashi MD , Arsalan Abu-Much MD , Nicole Cristell MD , Alexandra Popma MD , David J. Cohen MD, MSc , Sammy Elmariah MD, MPH , Martin B. Leon MD , Nicolas M. Van Mieghem MD, PhD , the TAVR UNLOAD trial study investigators","doi":"10.1016/j.shj.2025.100787","DOIUrl":"10.1016/j.shj.2025.100787","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 4","pages":"Article 100787"},"PeriodicalIF":2.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146070925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finerenone in Patients Undergoing TAVR for Nonrheumatic Aortic Stenosis: Insights From a Real-World Cohort","authors":"Faysal Massad MD , Osamah Badwan MD , Akiva Rosenzveig MD , Fawzi Zghyer MD , Zaid Shahrori MD , Issam Motairek MD , Taha Hatab MD , Radwan Alkhatib MD , Samir Kapadia MD","doi":"10.1016/j.shj.2025.100751","DOIUrl":"10.1016/j.shj.2025.100751","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100751"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midterm Outcomes of Transcatheter Edge-to-Edge Repair for Primary Mitral Regurgitation According to Anatomical Characteristics","authors":"Daryoush Samim MD ,&nbsp;Caroline Chong-Nguyen MD ,&nbsp;Yannick Hausammann B Med ,&nbsp;Mischa Külling MD ,&nbsp;Oliver Gaemperli MD ,&nbsp;Roberto Corti MD ,&nbsp;Joanna Bartkowiak MD ,&nbsp;Daijiro Tomii MD ,&nbsp;Domenico Angellotti MD ,&nbsp;Nicolas Brugger MD ,&nbsp;Thomas Pilgrim MD, MSc ,&nbsp;Patric Biaggi MD ,&nbsp;Fabien Praz MD ,&nbsp;Peter Martin Wenaweser MD","doi":"10.1016/j.shj.2025.100763","DOIUrl":"10.1016/j.shj.2025.100763","url":null,"abstract":"<div><h3>Background</h3><div>Mitral transcatheter edge-to-edge repair (M-TEER) is an established option for high-risk primary mitral regurgitation (PMR) patients, but data on the impact of anatomical complexity on prognosis are scarce and conflicting.</div></div><div><h3>Objectives</h3><div>The aims of this study were to characterize patients with severe PMR undergoing M-TEER, assess mid-term prognosis after M-TEER, and identify prognostic factors based on PMR mechanism.</div></div><div><h3>Methods</h3><div>Data from symptomatic PMR patients with severe PMR treated with M-TEER between July 2013 and October 2023 at two Swiss centers were collected retrospectively until 2017 and prospectively thereafter. Patients were categorized by lesion type: A2-P2 prolapse/flail vs. non-A2-P2 prolapse/flail. A subset was classified by mitral valve (MV) anatomical complexity (defined by the presence of ≥1 of the following: ≥moderate calcifications, Barlow’s disease, multiple prolapses, or commissural prolapses). Cox regression identified predictors of 1-year all-cause mortality.</div></div><div><h3>Results</h3><div>Among 315 patients (mean age 82.2 ± 6.3 years, 46.3% female, European System for Cardiac Operative Risk Evaluation II 5.1% ± 4.1%) followed for a median (interquartile range [IQR]) of 13 months (5-33), technical success was 93.0%. Compared with the non-A2-P2 prolapse/flail group (n = 186), the A2-P2 prolapse/flail group (n = 129) had better echocardiographic outcomes at discharge (residual mitral regurgitation [MR] ≤ 1+: 70.5 vs. 60.4%; <em>p</em> = 0.031) and superior symptomatic improvement at 1 year (New York Heart Association class ≤ II: 91.4 vs. 74.5%; <em>p</em> = 0.017) but similar 1-year all-cause mortality (15.1 vs. 18.8%; <em>p</em> = 0.492). Among patients classified by MV anatomical complexity (n = 143), patients with complex MV anatomy (n = 68) had a higher mortality at a median (IQR) follow-up of 22 months (9-36) compared to those with noncomplex MV anatomy (n = 75) (51.5 vs. 34.7%; <em>p</em> = 0.042). Multivariate analysis identified complex MV anatomy and severe renal failure as predictors of 1-year all-cause mortality.</div></div><div><h3>Conclusions</h3><div>MV anatomical characteristics have a significant influence on symptomatic improvement and all-cause mortality at 1 year and should be carefully considered during the selection of PMR patients for M-TEER.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100763"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Response After Mitral Valve Repair: Clinically Meaningful Relationship","authors":"Luis Nombela-Franco MD, PhD","doi":"10.1016/j.shj.2025.100757","DOIUrl":"10.1016/j.shj.2025.100757","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100757"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Electrosurgical Balloon-Assisted Leaflet Modification to Prevent Coronary Obstruction During Transcatheter Aortic Valve Replacement","authors":"Mostafa Naguib MD,&nbsp;Chantal Y. Asselin MSc, MD,&nbsp;Robert Kipperman MD,&nbsp;Leo Marcoff MD,&nbsp;Kostantinos P. Koulogiannis MD,&nbsp;Linda Gillam MD, MPH,&nbsp;Benjamin van Boxtel MD,&nbsp;John Brown III MD,&nbsp;Philippe Généreux MD,&nbsp;Gennaro Giustino MD","doi":"10.1016/j.shj.2025.100790","DOIUrl":"10.1016/j.shj.2025.100790","url":null,"abstract":"<div><h3>Background</h3><div>Coronary obstruction (CO) during transcatheter aortic valve replacement (TAVR) is associated with significant morbidity and mortality. UNICORN (Undermining Iatrogenic Coronary Obstruction with Radiofrequency Needle) is a novel technique designed to prevent CO by performing electrosurgical leaflet traversal followed by intraleaflet valve implantation or complete leaflet laceration accomplished using noncompliant balloons. However, its efficacy and safety are not well established.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed all patients who underwent UNICORN-assisted TAVR for both valve-in-valve and native valve procedures at a single high-volume center between September 2024 and September 2025. Patients were selected based on preprocedural cardiac computed tomography demonstrating high anatomic risk for CO. In all cases, the target leaflet was traversed using an electrified 0.014″ wire, followed by serial noncompliant balloon dilatations of the leaflet to either achieve complete leaflet laceration or to accommodate for intra-leaflet valve implantation. Balloon-expandable valves were used in all procedures.</div></div><div><h3>Results</h3><div>Fifteen patients underwent UNICORN-assisted TAVR. Twelve were valve-in-valve cases, and 3 involved native valves. The right coronary cusp was targeted in 11 procedures and the left in 6, including 2 requiring bileaflet modification. Technical success was achieved in all cases (100%). Procedural success was achieved in 93.3%. One patient developed acute CO due to skirt-related occlusion after a high implant in a degenerated self-expanding valve, requiring single-vessel coronary artery bypass surgery. No bailout coronary stenting was required. There were no in-hospital deaths or disabling strokes. All patients were alive at 30-day follow-up.</div></div><div><h3>Conclusions</h3><div>In this single-center experience, UNICORN appears technically reproducible, effective in preventing CO, and safe in TAVR patients at high-risk for CO.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100790"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re-Examining Patient–Prosthesis Mismatch After Transcateter Aortic Valve Replacement: The Role of Flow, Remodeling, and Expansion Dynamics","authors":"Ashish H. Shah MD, MD-Research (UK)","doi":"10.1016/j.shj.2025.100761","DOIUrl":"10.1016/j.shj.2025.100761","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100761"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Replacement for Severe Native Aortic Valve Regurgitation: A Multicenter and International Registry","authors":"Sant Kumar MD ,&nbsp;Ashish Pershad MD ,&nbsp;David Elison MD ,&nbsp;EiEi Thwe MD ,&nbsp;Jacopo Farina MD ,&nbsp;Ahmad Jabri MD ,&nbsp;Ivan Hanson MD ,&nbsp;Amr Abbas MD ,&nbsp;Pedro A. Villablanca MD ,&nbsp;Nezar Falluji MD ,&nbsp;Simone Biscaglia MD ,&nbsp;Carlo Tumscitz MD ,&nbsp;Timothy Byrne DO ,&nbsp;Francesco Saia MD ,&nbsp;Soundos Moualla MD ,&nbsp;Hursh Naik MD","doi":"10.1016/j.shj.2025.100762","DOIUrl":"10.1016/j.shj.2025.100762","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"10 3","pages":"Article 100762"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}