Stomatologiya最新文献

{"title":"[Planning of occlusal load in designing the occlusal surface of posterior teeth based on 3D analysis].","authors":"A N Ryakhovsky","doi":"10.17116/stomat202410306135","DOIUrl":"https://doi.org/10.17116/stomat202410306135","url":null,"abstract":"<p><strong>The aim of the study: </strong>Was to determine the possibility of calculating the parameters of the occlusal surface of fixed dentures.</p><p><strong>Materials and methods: </strong>An analysis of dependence between the area of the occlusal surface and the area of the support structures (tooth root/implant), between the severity of the occlusal relief (tubercles of teeth) on the length of the root/implant was carried out.</p><p><strong>Results: </strong>The nearness of the Kurlandsky periodontal coefficients and Oksman masticatory coefficients with the calculated coefficients obtained on the basis of 3D analysis of the lateral teeth anatomy has been established. A method for calculating the maximum permissible vertical and lateral loads on chewing teeth is proposed.</p><p><strong>Conclusion: </strong>Recommendations are given on the design of the shape of the occlusal surface depending on the periodontal condition and the severity of the external thread of the implant.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 6","pages":"35-47"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparative analysis of the state of the microvasculature of the oral mucosa in persons with metabolic syndrome in the aspect of orthopedic dental rehabilitation].","authors":"A V Khizhuk, A A Stafeev, E K Krechina, S I Soloviev","doi":"10.17116/stomat202410306215","DOIUrl":"https://doi.org/10.17116/stomat202410306215","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the dynamics of the condition of the mucous membrane in patients with metabolic syndrome at the stage of preparation for dental prosthetics using dental implants.</p><p><strong>Material and methods: </strong>255 patients (151 women and 104 men) aged from 35 to 65 years were examined. 3 groups were formed: 2 study groups and a comparison group. Groups 1 and 2 included individuals with excess body weight and MS. The control group consisted of 88 people without MS. A dynamic analysis of the state of microcirculation in the gum mucosa was carried out using the laser Doppler flowmetry method at the stages before dental implantation and before prosthetics supported by dental implants.</p><p><strong>Results: </strong>The data obtained during the study from the analysis of microcirculation parameters indicated not only a decrease in the intensity of blood flow in people with MS, but also a decrease in vasomotor activity of blood vessels. A comparison of the indicators of these individuals with similar data in individuals without metabolic disorders showed that in patients with MS, changes in microcirculation in periodontal tissues during the inflammatory-destructive process are more pronounced, especially in the group of individuals with hypertension and/or type 2 diabetes, which manifested by a decrease in the level of tissue blood flow to 20.9%, the intensity of tissue blood flow to 46% and vasomotor activity to 33.6% as a result of a decrease in active and passive regulatory mechanisms.</p><p><strong>Conclusion: </strong>Disorders of microcirculation in the tissues of the mouth against the background of MS of varying severity led to a decrease in the activity of blood flow and tissue perfusion, which indicates a deterioration in tissue trophism, especially in persons with MS complicated by hypertension and/or type 2 diabetes. This trend predetermines a negative impact on the condition of the tissues around the DI, both before its installation and during the period of adaptation to orthopedic structures, this will be especially pronounced in persons with a burdened somatic status. Before carrying out dental rehabilitation, it is necessary to take into account all the risks of developing possible complications caused by the general condition of the organs and systems of patients with MS.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 6. Vyp. 2","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The effect of vitamin D deficiency on the content of some soluble signaling molecules in the oral fluid in individuals with dental caries].","authors":"E V Fefelova, M V Maksimenya, A S Putneva, I D Ushnitsky, M N Mishchenko, T M Karavaeva","doi":"10.17116/stomat202410302112","DOIUrl":"https://doi.org/10.17116/stomat202410302112","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the sthudy is to sthudy the level of soluble Immune Checkpoint Molecules (B7.2, CTLA-4, Tim-3, Lag-3, PD-1) in the oral fluid during dental caries with the background of a lack and/or deficiency of 25-hydroxy-vitamin D in body.</p><p><strong>Materials and methods: </strong>During the research 3 groups of people were formed, each one of them included 17 people aged from 20 to 24 years. The first group included students with high-intensity caries (above 9 DMFt index) and 25-hydroxy-vitamin D levels in blood serum >30 ng/ml, the second included students with high caries intensity and 25-hydroxy-vitamin D levels <30 ng/ml. The control group consisted of students with an average DMFt index of 1.5 (from 0 to 3) and a level of 25(OH)D in the blood more than 30 ng/ml. To determine the content of B7.2 (CD86), CTLA-4, Tim-3, Lag-3, PD-1, the Human Vascular Inflammation Panel 1 multiplex analysis kit from Biolegend (USA) was used.</p><p><strong>Results: </strong>The results of the research showed that during dental caries with a normal level of 25-hydroxy-vitamin D there are no significant changes in the content of Immune Checkpoint Molecules. With the background of deficiency and lack of 25-hydroxy-vitamin D there is a decrease in the amount of B7.2, LAG-3, Tim-3 and PD-1. These changes are being aggravated with an increase of the caries intensity.</p><p><strong>Conclusion: </strong>Vitamin D deficiency leads to a decrease in mucosal immunity of the oral cavity, the multiplication of pathogenic microorganisms, which in turn, releasing various metabolites, including cytokine-like substances, aggravate the pathological process and intensify carious lesions.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 2","pages":"12-17"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Dental gel Cholisal at the stage of conservative treatment of inflammatory periodontal diseases].","authors":"I M Rabinovich, M V Snegirev, N B Petrukhina, O A Boriskina, M V Saltovets","doi":"10.17116/stomat2024103021","DOIUrl":"https://doi.org/10.17116/stomat2024103021","url":null,"abstract":"<p><strong>Purpose of the study: </strong>To study the effectiveness of the drug Cholisal as part of the conservative treatment of chronic periodontitis.</p><p><strong>Material and methods: </strong>We selected 100 patients aged 35 to 65 years of both sexes with a diagnosis of moderate chronic periodontitis in the acute stage with a periodontal pocket depth of 3.5-5 mm. Depending on the tactics of conservative treatment of periodontitis, patients were divided into two groups of 50 people. In the main group, Cholisal dental gel was used as part of complex conservative treatment, and in the control group, Metrogil-denta gel was used. To assess the effectiveness of treatment, a dental examination of patients was carried out with an index assessment of the condition of periodontal tissues and a biochemical analysis of the content of arachidonic acid and prostaglandin E2 in gingival blood, comparing the indicators before treatment and 14 days after the start of treatment.</p><p><strong>Results: </strong>When the drug Cholisal was included in complex treatment, 14 days from the start of treatment, patients experienced a statistically significant decrease in the depth of periodontal pockets from 4.7±0.32 mm to 3.6±0.19, and the Green-Vermillion hygiene index by 60.7%, Silness-Loe plaque index by 73.1%, PMA index by 68.8%, Muhlemann-Cowell bleeding index by 68.0% (<i>p</i><0.001 compared to baseline). When Metrogil-denta gel was used in complex therapy, the effectiveness of treatment was lower: the depth of periodontal pockets did not change significantly (from 4.5±0.22 mm to 4.2±0.17 mm, <i>p</i>>0.05), reduction in the hygiene index Green-Vermillion was 51.9%, Silness-Loe plaque index - 64.0%, PMA index - 43.7%, Muhlemann-Cowell bleeding index - 45.8% (<i>p</i><0.001 compared to baseline, <i>p</i><0.001 compared to the main group). A laboratory study showed that in patients of the main group, after completing a course of conservative treatment, the content of biomarkers of inflammation significantly decreased compared to the initial level (<i>p</i><0.05), while in patients of the control group the content of arachidonic acid and prostaglandin E2 in the gingival blood during the study period did not change significantly (<i>p</i>>0.05 compared to the initial level).</p><p><strong>Conclusions: </strong>The use of the drug Cholisal in the conservative treatment of chronic periodontitis has demonstrated more pronounced positive dynamics of clinical and biochemical parameters compared to traditional therapy, which suggests its high effectiveness.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 2","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The use of artificial intelligence in modern dentistry in the Russian Federation].","authors":"F F Losev, A A Sorokina, A K Salakhov, S P Dokin","doi":"10.17116/stomat202410305142","DOIUrl":"10.17116/stomat202410305142","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study is to identify the prospects and possibilities of using artificial intelligence (AI) and domestic software in the provision of organization dental care in the Russian Federation.</p><p><strong>Materials and methods: </strong>An analysis of the actual situation on the use of domestic computer programs using AI for the provision of medical care in the Russian Federation was carried out based on information presented on the official websites of software developers, in scientific sources of information and analytical systems of the Higher Attestation Commission, eLibrary, PubMed, Scopus, Google Scholar. Content analysis and analytical method were used, followed by interpretation of the data and conclusions obtained.</p><p><strong>Results: </strong>To date, information technologies and domestic software aimed at automation, improving safety and quality of medical care are being actively introduced. The requirements for AI-based programs are justified, namely: safety, accessibility for medical professionals and patients, as well as high competitiveness among developers. AI helps to process large amounts of medical data, contributes to the creation of a personalized approach to patient treatment, automates and optimizes administrative processes in healthcare, increases the accuracy of diagnosis, identification of early signs of the disease, predicts the outcome of treatment, neural networks accelerate the development of remote healthcare and telemedicine. However, it is the doctor who should be responsible for the decisions made based on the \"tips\" and recommendations of artificial intelligence.</p><p><strong>Conclusion: </strong>The use of computer programs using artificial intelligence in dentistry opens up significant prospects for improving the quality of medical care, interaction with patients and improving the level of education of doctors. The most popular programs will be in therapeutic and pediatric dentistry, aimed, among other things, at the prevention of dental diseases.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 5","pages":"42-45"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Yevdokimov's Five-Year Plan. On the 140th anniversary of his birth].","authors":"O O Yanushevich, K A Pashkov, O N Konon, V A Bondar'","doi":"10.17116/stomat202410304181","DOIUrl":"https://doi.org/10.17116/stomat202410304181","url":null,"abstract":"<p><p>The name of Alexander Ivanovich Evdokimov is widely known to dentists all over the world. An outstanding leader, teacher, scientist and doctor, a wonderful man and a wonderful family man - this is how the first and only Hero of Socialist Labor in dentistry remains in the memory of grateful descendants. In 2012, by the decision of the Minister of Health and Social Development of the Russian Federation T.A. Golikova, his name was given to the Moscow State University of Medicine and Dentistry, and the textbooks published under his pen are still relevant today, in the year when we celebrate the 140th anniversary of the coryphaeus' birth.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 4","pages":"81-88"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Need for prosthodontics of permanent teeth in children aged 8-18 years].","authors":"P S Timoshenko, M V Korolenkova","doi":"10.17116/stomat202410304167","DOIUrl":"https://doi.org/10.17116/stomat202410304167","url":null,"abstract":"<p><strong>Objective: </strong>To reveal need for prosthodontics in permanent teeth in children aged 8-18 years.</p><p><strong>Materials and methods: </strong>The study was performed in Khimki Dental Municipal Clinic. Dental examination and radiological studies were conducted in 97 primary patients aged 8-18 years. Indications for prosthodontics in permanent teeth were occlusal deterioration index more than 40% and crown decay of more than 50% in incisors and canines. Additional features were registered including DMFT index, the presence of extracted teeth and teeth after root canal treatment, as well and teeth with extensive restorations with resins and marginal seal quality.</p><p><strong>Results: </strong>From 97 primary patients (27.8%) children needed prosthodontics in permanent teeth (in average 2.3±2.1 teeth): 1 tooth in 10 children, 2 teeth in 11 children, 3 teeth in 1 child, 4 teeth in 3 children and 4 teeth in 2 children. Mean DMFT was 8.1±4.5 teeth. Six children already had extracted permanent teeth (9 teeth in total). Half of the teeth (49.2%) which needed orthodontic treatment had history of root canal treatment while 46% needed primary or secondary endodontic treatment. Occlusal deterioration index was more than 40% in 41.3% of cases, more than 60% in 49.2% of teeth and more than 80% in 9.52% of teeth. From all the teeth restored with composite resins 41.7% had good marginal seal but 58.3% showed macroscopic signs of marginal leakage.</p><p><strong>Conclusion: </strong>Our study shows high percentage of adolescents having need for prosthodontics in permanent teeth and unjustified widening of indications for direct resin restorations in this group of patients.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 4","pages":"67-69"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The use of alginate plates with a complex of antimicrobial peptides and cytokines after surgical interventions on periodontal tissues as a prevention of early postoperative complications].","authors":"V A Brizgalova, G S Runova, Z E Revazova, Z E Lalieva, M Yu Dorzhieva, A A Babanina","doi":"10.17116/stomat202410305119","DOIUrl":"10.17116/stomat202410305119","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the possibility of improving the effectiveness of early postoperative healing in patients after surgical interventions on periodontal tissues due to the topical application of alginate plates with a complex of antimicrobial peptides and cytokines.</p><p><strong>Materials and methods: </strong>40 patients who underwent periodontal surgery were examined: operations aimed at bone tissue regeneration; mucogingival operations (elimination of gum recession), corticotomy with osteoplasty, apical surgery. The patients were randomly divided into 2 groups of 20 people (main and control). At the end of the operation, alginate plates with a complex of antimicrobial peptides and cytokines were applied to the surgical intervention area to the main group. Further, 2-3 times a day, it was recommended to apply them independently for 10-14 days, after antiseptic treatment. In the control group, they were limited to double treatment with 0.05% chlorhexidine bigluconate solution daily for two weeks. Follow-up examinations and evaluation of the index of early wound healing, as well as indicators of postoperative pain, bleeding and edema were carried out on day 3, 7, 14.</p><p><strong>Results: </strong>In all patients in the early postoperative period, positive dynamics of healing were observed, however, in the main group, pain indicators, as well as bleeding and swelling, according to a patient survey, were less pronounced. The early wound healing index was also more positive in the main group - on days 3, 7 and 14 there was a more intense decrease. (1.9 points.,1.5 points., 1.2 points., respectively, and in the control group 2.3 points., 2.1 points., 1.9 points.).</p><p><strong>Conclusion: </strong>Local application of alginate plates with a complex of antimicrobial peptides and cytokines in the early postoperative period allows to improve early wound healing after surgical interventions on periodontal tissues, and can be recommended for use at a dental appointment, as well as for use at home.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 5","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Precancers of the oral mucosa: clinic, diagnostics].","authors":"O F Rabinovich, I M Rabinovich, I I Babichenko, K V Umarova, L F Bekmurzova","doi":"10.17116/stomat20241030215","DOIUrl":"https://doi.org/10.17116/stomat20241030215","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study. Improving the efficiency of diagnosis and detailing the features of the clinic of «potentially malignant» diseases of the oral mucosa.</p><p><strong>Materials and methods: </strong>Clinical and laboratory examination of 124 patients of the department of oral mucosa diseases aged 35 to 80 years, among whom there were 75 women and 49 men, with diseases such as erythroplakia - 12 patients, verrucous leukoplakia - 52 patients, erosive form of leukoplakia - 35 patients, cheilitis Manganotti - 25 patients. Histological and immunohistochemical methods of investigation were used as diagnostics. To assess the proliferative activity of epithelial cells, the determination of the Ki-67 index was used. The synthesis of keratin 15 (K15) in epithelial layers was determined as a diagnostic criterion for the severity of neoplasia. The expression of human papillomavirus type 16 (HPV 16) antigens and p16INK4a protein in epithelial cells was studied, as well as the expression of p53 protein.</p><p><strong>Results: </strong>A high prevalence of p53 mutations was observed in patients with erythroplakia. In leukoplakia, the expression of the Ki-67 protein was detected in the cell nuclei in both the basal and parabasal layers of the multilayer squamous epithelium, in 77% of cases, the expression of the p16INK4a protein in the epithelial nuclei with varying degrees of dysplastic changes was noted, and a positive reaction to HPV16 was also observed in the cell nuclei and cytoplasm of epithelial cells in the basal, parabasal and spiny epithelial layers. The appearance of K15 in the cytoplasm of cells above the basal layer with abrasive precancerous cheilitis was found in 48% of cases.</p><p><strong>Conclusion: </strong>To diagnose early manifestations of neoplastic processes in «potentially malignant» diseases of the oral mucosa, it is necessary to use both classical histological and immunohistochemical methods of investigation with various markers.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 2","pages":"5-11"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The results of vital pulpotomy in primary teeth in children with negative behavior].","authors":"E E Maslak, E N Arjenovskaya","doi":"10.17116/stomat202410302177","DOIUrl":"https://doi.org/10.17116/stomat202410302177","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study. Comparative assessment of the results of vital pulpotomy in primary teeth in children with negative behavior when using non-drug behavior correction or sedation with preserved consciousness.</p><p><strong>Materials and methods: </strong>The proportions (%), 95% Confidence Interval (CI), the Student's criterion and χ² for assessment of the difference between indicators were calculated. After 24 months, the pulpotomy efficiency in the 1^st group was lower than in the 2^nd group: 81.7% (95% CI 74.7-88.6%) and 89.2% (95% CI 83.6-94.7%), respectively, <i>p</i>>0.05.</p><p><strong>Results: </strong>The proportions (%), 95% Confidence Interval (CI), the Student's criterion and χ² for assessment of the difference between indicators were calculated. After 24 months, the pulpotomy efficiency in the 1^st group was lower than in the 2^nd group: 81.7% (95% CI 74.7-88.6%) and 89.2% (95% CI 83.6-94.7%), respectively, <i>p</i>>0.05.</p><p><strong>Conclusion: </strong>The treatment of the children aged 3-6 years with negative behavior under sedation with preserved consciousness increased the results of pulpotomy in primary teeth mainly due to the improvement of the quality of restorations.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"103 2","pages":"77-79"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}