Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0016
P. Novak
{"title":"Case 11: Postural Tachycardia Syndrome with Positive Antibodies Against the P/Q-type of Calcium Channel","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0016","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0016","url":null,"abstract":"Orthostatic symptoms in postural tachycardia syndrome (POTS) (shortness of breath, lightheadedness, fatigue, and others) are due cerebral hypoperfusion associated with reduced cerebral blood flow velocity (CBFv), which is induced by hyperventilation. Immunomodulatory therapy using immune globulins may be effective in small fiber neuropathy with a positive antibody against the P/Q-type calcium channel.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124120927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0008
P. Novak
{"title":"Case 3: Syncope Without Hyperventilation","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0008","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0008","url":null,"abstract":"This case presents syncope, neurally mediated, and mixed. Small fiber neuropathy (SFN) presented as sensory and length-dependent, and the typical hyperventilatory response with a decline of end tidal CO2 just before the syncope was absent.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116268960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0062
P. Novak
{"title":"Case 57: Small Fiber Neuropathy and Hypocapnic Cerebral Hypoperfusion with Elevated Antibodies to N-type Calcium Channel","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0062","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0062","url":null,"abstract":"Autonomic testing revealed severe small fiber neuropathy and severe hypocapnic cerebral hypoperfusion (HYCH). Both findings are relevant to patient symptoms. The dysautonomia was mild and of questionable clinical significance.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124398797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0018
P. Novak
{"title":"Case 13: Postural Tachycardia Syndrome with Syncope","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0018","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0018","url":null,"abstract":"The tilt provoked most of the patient’s symptoms, including dizziness, nausea and loss of consciousness, which was consistent with postural tachycardia syndrome and neurally mediated syncope of mixed type.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130574280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0041
P. Novak
{"title":"Case 36: Orthostatic Hypertension","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0041","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0041","url":null,"abstract":"Orthostatic hypertension is a syndrome associated with a rise in orthostatic blood pressure, for example in essential hypertension, diabetes, and dysautonomia. Therapy with calcium channel blockers may reduce hypertension and also may improve cerebral perfusion since calcium channel blockers dilate cerebral vessels.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130655102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0021
P. Novak
{"title":"Case 16: Autonomic Failure or Postural Tachycardia Syndrome?","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0021","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0021","url":null,"abstract":"Small fiber neuropathy is associated with adrenergic failure. Anxiety is common and occasionally can be identified as a transient elevation of heart rate, blood pressure, and cerebral blood flow velocity.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126933575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0012
P. Novak
{"title":"Case 7: Syncope, Double","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0012","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0012","url":null,"abstract":"Patient presents with frequent spells of passing out. Tilt test provoked two episodes of neurally mediated syncope, mixed type. Although rare, neurally mediated syncope can occur in the supine position. A second syncope can follow the first syncope almost immediately.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126295357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0051
P. Novak
{"title":"Case 46: Amyotrophic Lateral Sclerosis","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0051","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0051","url":null,"abstract":"A 61-year-old man presents with a progressive exertional dyspnea, fatigue, orthostatic intolerance, and weakness. Autonomic testing was normal. However, there was evidence of respiratory failure associated with tachypnea and hypocapnia. Respiratory failure is characteristic of amyotrophic lateral sclerosis (ALS).","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126987123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0044
P. Novak
{"title":"Case 39: Hypothermia in Frontotemporal Dementia","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0044","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0044","url":null,"abstract":"This case illustrates severe generalized autonomic failure associated with frontotemporal dementia (FTD) and hypothermia. The tilt test provoked severe sustained orthostatic hypotension associated with reduced heart rate response and a decline in cerebral blood flow velocity. Thermoregulation is a vital function of autonomic nervous system.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133166443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0048
P. Novak
{"title":"Case 44: Multiple System Atrophy","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0048","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0048","url":null,"abstract":"Multiple system atrophy (MSA) is associated with severe autonomic failure of the central nervous system. Autonomic testing showed a typical MSA pattern including severe sympathetic adrenergic and parasympathetic failure with orthostatic hypotension and cerebral hypoperfusion.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133628884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}