Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0060
P. Novak
{"title":"Case 55: Small Fiber Neuropathy with Autonomic Failure","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0060","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0060","url":null,"abstract":"This case demonstrates severe autonomic failure with orthostatic hypotension affecting cardiovagal and sympathetic adrenergic fibers and associated with small fiber neuropathy. Small fiber neuropathy is severe, mixed, and affecting sensory and autonomic fibers, non–length-dependent. Orthostatic cerebral blood flow velocity was reduced throughout the tilt, indicative of autoregulation failure.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131212047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0023
P. Novak
{"title":"Case 18: Postural Tachycardia Syndrome and Small Fiber Neuropathy in Polycystic Ovary Syndrome","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0023","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0023","url":null,"abstract":"Postural tachycardia syndrome and small fiber neuropathy can be associated with polycystic ovary syndrome or with the use of metformin.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132998943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0105
P. Novak
{"title":"Case 100: Dizziness After Concussion","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0105","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0105","url":null,"abstract":"Low cerebral blood flow velocity (CBFv) can be associated with signs of cerebral hypoperfusion with dizziness in concussion. The tilt test with CBFv monitoring can be helpful to differentiate this from other causes of dizziness.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"330 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134471582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0082
P. Novak
{"title":"Case 77: Painful Small Fiber Neuropathy in Posttreatment Lyme Disease Syndrome","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0082","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0082","url":null,"abstract":"This case illustrates autonomic failure in painful post-Lyme disease syndrome. Autonomic testing has shown supine hypertension, orthostatic hypotension, and hypocapnic cerebral hypoperfusion (HYCH). Small fiber neuropathy was painful, affecting sensory fibers. Patient noted improvement in the pain by about 40% after 12 month of intravenous immune globulins.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132356776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0039
P. Novak
{"title":"Case 34: Hypocapnic Cerebral Hypoperfusion and Effect of End Tidal CO2","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0039","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0039","url":null,"abstract":"Patient experienced symptoms of orthostatic intolerance due to cerebral hypoperfusion and to hypocapnic hyperventilation, which is typical for hypocapnic cerebral hypoventilation. (HYCH). Voluntary hyperventilation in supine position reproduced symptoms and findings.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128324838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0093
P. Novak
{"title":"Case 88: Intermittent Vision Loss After Cervical Spine Injury","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0093","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0093","url":null,"abstract":"Cervical spine injury may result in postural tachycardia syndrome and autonomic dysreflexia.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116591266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0080
P. Novak
{"title":"Case 75: Small Fiber Neuropathy, Cerebral Autoregulatory Failure, and Posttreatment Lyme Disease Syndrome","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0080","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0080","url":null,"abstract":"This patient has a history of Lyme disease with persistent cognitive and sensory symptoms, and he may have posttreatment Lyme disease syndrome (PLDS). The autonomic testing showed small fiber neuropathy and cerebral autoregulatory failure.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123826666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0002
P. Novak
{"title":"Functional Neuroanatomy of Autonomic Nervous System","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0002","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0002","url":null,"abstract":"A basic understanding of the functional and physiological structure of the autonomic nervous system (ANS) is essential in interpreting test results. This chapter summarizes the functional anatomy of the ANS. The ANS has been divided into the central autonomic system (CAN), also called preganglionic system, and the peripheral (or postganglionic system), which includes the parasympathetic system, sympathetic system, and enteric system. The anatomy and functions of the ANS and its various divisions are explained. Also described is the anatomy and functions of the baroreceptor reflex (BR), which is important in controlling the heart rate and blood pressure.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132725291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/med/9780190889227.003.0047
P. Novak
{"title":"Case 42: Multiple System Atrophy Versus Parkinson’s Disease?","authors":"P. Novak","doi":"10.1093/med/9780190889227.003.0047","DOIUrl":"https://doi.org/10.1093/med/9780190889227.003.0047","url":null,"abstract":"This patient showed evidence of mild but widespread autonomic dysfunction. These findings are nonspecific and can be seen in variety of central (α-synucleinopathies) and peripheral (autonomic neuropathy/ganglionopathy) disorders. Clinical workup for neuropathy showed elevated acetylcholine ganglionic neuronal antibodies. Immunotherapy with intravenous immunoglobulins for suspected autoimmune autonomic neuropathy was recommended.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124062713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autonomic TestingPub Date : 2019-03-01DOI: 10.1093/MED/9780190889227.003.0064
P. Novak
{"title":"Case 59: Small Fiber Neuropathy and Autonomic Failure with Elevated Voltage-Gated Potassium Channel Antibodies","authors":"P. Novak","doi":"10.1093/MED/9780190889227.003.0064","DOIUrl":"https://doi.org/10.1093/MED/9780190889227.003.0064","url":null,"abstract":"This case demonstrates severe autonomic failure associated with autoimmune small fiber neuropathy that was positive for elevated voltage-gated potassium channel (VGKC) antibodies. Adrenergic autonomic failure is associated with orthostatic hypotension. Low cerebral blood flow velocity during the tilt was associated with cerebral vasoconstriction.","PeriodicalId":358532,"journal":{"name":"Autonomic Testing","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124797834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}